Ian A Wilson (Ian Wilson)

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 99

Top Topics

Structural Basis

Plasmodium Falciparum

Hepatitis C Virus

Top Venues

Nature communications

Science (New York, N.Y.)

Science advances

Proceedings of the National Academy of Sciences of the United States of America

This page only lists publications with an associated author ORCID identifier.

Publications

Martin F Flajnik, Robyn L Stanfield, Elena N Pokidysheva, Sergei P Boudko, Ian A Wilson, Yuko Ohta
An Ancient MHC-Linked Gene Encodes a Nonrearranging Shark Antibody, UrIg, Convergent with IgG. Journal of immunology (Baltimore, Md. : 1950) (2023)
Gregory M Martin, Jonathan L Torre, Tossapol Pholcharee, David Oyen, Yevel Flores-Garcia, Grace Gibson, Re'em Moskovitz, Nathan Beutler, Diana D Jung, Jeffrey Copps, Wen-Hsin Lee, Gonzalo Gonzalez-Paez, Daniel Emerling, Randall S MacGill, Emily Locke, C Richter King, Fidel Zavala, Ian A Wilson, Andrew B Ward
Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection. Nature communications 14 (1) (2023)
Laetitia E Misson, Hejun Liu, Gabriel Ozorowski, Quoc Tran, Jordan L Woehl, Irene Khalek, Jessica M Smith, Shawn Barman, Fangzhu Zhao, Celina Keating, Oliver Limbo, Megan Verma, Jingjia Liu, Robyn L Stanfield, Xueyong Zhu, Hannah L Turner, Devin Sok, Po-Ssu Huang, Dennis R Burton, Andrew B Ward, Ian A Wilson, Joseph G Jardine
Fully synthetic platform to rapidly generate tetravalent bispecific nanobody-based immunoglobulins. Proceedings of the National Academy of Sciences of the United States of America 120 (24) (2023)
Ruiqi Huang, Gabrielle F Warner, Yunjeong Kim, Robyn L Stanfield, Amrinder Singh, Maria A Martinez-Yamout, Gerard J Kroon, Jonathan L Torre, Abigail M Jackson, Abigail Kelley, Namir Shaabani, Baisen Zeng, Michael Bacica, Wen Chen, Christopher Warner, Jasmina Radoicic, Joongho Joh, Krishani Dinali Perera, Huldah Sang, Tae Kim, Jianxiu Yao, Fangzhu Zhao, Devin Sok, Dennis R Burton, Jeff Allen, William Harriman, Waithaka Mwangi, Donghoon Chung, John R Teijaro, Andrew B Ward, H Jane Dyson, Peter E Wright, Ian A Wilson, Kyeong-Ok Chang, Duncan McGregor, Vaughn V Smider
The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2. Proceedings of the National Academy of Sciences of the United States of America 120 (39) (2023)
Meng Yuan, Ziqi Feng, Huibin Lv, Natalie So, Ivana R Shen, Timothy J C Tan, Qi Wen Teo, Wenhao O Ouyang, Logan Talmage, Ian A Wilson, Nicholas C Wu
Widespread impact of immunoglobulin V gene allelic polymorphisms on antibody reactivity. bioRxiv : the preprint server for biology (2023)
Timothy J C Tan, Zongjun Mou, Ruipeng Lei, Wenhao O Ouyang, Meng Yuan, Sophie Ge Song, Raiees Andrabi, Ian A Wilson, Collin Kieffer, Xinghong Dai, Kenneth A Matreyek, Nicholas C Wu
High-throughput identification of prefusion-stabilizing mutations in SARS-CoV-2 spike. Nature communications 14 (1) (2023)
Yupeng Feng, Meng Yuan, John M Powers, Mengyun Hu, Jennifer E Munt, Prabhu S Arunachalam, Sarah R Leist, Lorenza Bellusci, Junghyun Kim, Kaitlin R Sprouse, Lily E Adams, Sumana Sundaramurthy, Xueyong Zhu, Lisa M Shirreff, Michael L Mallory, Trevor D Scobey, Alberto Moreno, Derek T O'Hagan, Harry Kleanthous, Francois J Villinger, David J Veesler, Neil P King, Mehul S Suthar, Surender Khurana, Ralph S Baric, Ian A Wilson, Bali Pulendran
Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine. Science translational medicine 15 (695) (2023)
Gregory M Martin, Monica L Fernández-Quintero, Wen-Hsin Lee, Tossapol Pholcharee, Lisa Eshun-Wilson, Klaus R Liedl, Marie Pancera, Robert A Seder, Ian A Wilson, Andrew B Ward
Structural basis of epitope selectivity and potent protection from malaria by PfCSP antibody L9. Nature communications 14 (1) (2023)
Yi-Nan Zhang, Jennifer Paynter, Aleksandar Antanasijevic, Joel D Allen, Mor Eldad, Yi-Zong Lee, Jeffrey Copps, Maddy L Newby, Linling He, Deborah Chavez, Pat Frost, Anna Goodroe, John Dutton, Robert Lanford, Christopher Chen, Ian A Wilson, Max Crispin, Andrew B Ward, Jiang Zhu
Single-component multilayered self-assembling protein nanoparticles presenting glycan-trimmed uncleaved prefusion optimized envelope trimmers as HIV-1 vaccine candidates. Nature communications 14 (1) (2023)
Meng Yuan, Linghang Peng, Deli Huang, Amanda Gavin, Fangkun Luan, Jenny Tran, Ziqi Feng, Xueyong Zhu, Jeanne Matteson, Ian A Wilson, David Nemazee
Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4. bioRxiv : the preprint server for biology (2023)
Gregory M Martin, Monica L Fernández-Quintero, Wen-Hsin Lee, Tossapol Pholcharee, Lisa Eshun-Wilson, Klaus R Liedl, Marie Pancera, Robert A Seder, Ian A Wilson, Andrew B Ward
Structural basis of epitope selectivity and potent protection from malaria by PfCSP antibody L9. Nature communications 14 (1) (2023)
Gregory M Martin, Monica L Fernández-Quintero, Wen-Hsin Lee, Tossapol Pholcharee, Lisa Eshun-Wilson, Klaus R Liedl, Marie Pancera, Robert A Seder, Ian A Wilson, Andrew B Ward
Structural basis of epitope selectivity and potent protection from malaria by PfCSP antibody L9. Nature communications 14 (1) (2023)
Yupeng Feng, Meng Yuan, John M Powers, Mengyun Hu, Jennifer E Munt, Prabhu S Arunachalam, Sarah R Leist, Lorenza Bellusci, Junghyun Kim, Kaitlin R Sprouse, Lily E Adams, Sumana Sundaramurthy, Xueyong Zhu, Lisa M Shirreff, Michael L Mallory, Trevor D Scobey, Alberto Moreno, Derek T O'Hagan, Harry Kleanthous, Francois J Villinger, David J Veesler, Neil P King, Mehul S Suthar, Surender Khurana, Ralph S Baric, Ian A Wilson, Bali Pulendran
Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine. Science translational medicine 15 (695) (2023)
Fangzhu Zhao, Meng Yuan, Celina Keating, Namir Shaabani, Oliver Limbo, Collin Joyce, Jordan L Woehl, Shawn Barman, Alison Burns, Quoc Tran, Xueyong Zhu, Michael J Ricciardi, Linghang Peng, Jessica Smith, Deli Huang, Bryan Briney, Devin Sok, David Nemazee, John R Teijaro, Ian A Wilson, Dennis R Burton, Joseph G Jardine
Broadening a SARS-CoV-1-neutralizing antibody for potent SARS-CoV-2 neutralization through directed evolution. Science signaling 16 (798) (2023)
Eduard Puente-Massaguer, Kirill A Vasilyev, Annika Beyer, Madhumathi Loganathan, Benjamin Francis, Michael J Scherm, Guha Asthagiri Arunkumar, Irene González Domínguez, Xueyong Zhu, Ian A Wilson, Lynda Coughlan, Weina Sun, Peter Palese, Florian Krammer
Chimeric hemagglutinin split vaccines elicit broadly cross-reactive antibodies and protection against group 2 influenza viruses in mice. Science advances 9 (37) (2023)
Chang-Ki Oh, Tomohiro Nakamura, Nathan Beutler, Xu Zhang, Juan Piña-Crespo, Maria Talantova, Swagata Ghatak, Dorit Trudler, Lauren N Carnevale, Scott R McKercher, Malina A Bakowski, Jolene K Diedrich, Amanda J Roberts, Ashley K Woods, Victor Chi, Anil K Gupta, Mia A Rosenfeld, Fiona L Kearns, Lorenzo Casalino, Namir Shaabani, Hejun Liu, Ian A Wilson, Rommie Elizabeth Amaro, Dennis R Burton, John Yates Iii, Cyrus Becker, Thomas F Rogers, Arnab K Chatterjee, Stuart A Lipton
Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection. Nature chemical biology (2022)
Linling He, Anshul Chaudhary, Xiaohe Lin, Cindy Sou, Tanwee Alkutkar, Sonu Kumar, Timothy Ngo, Ezra Kosviner, Gabriel Ozorowski, Robyn L Stanfield, Andrew B Ward, Ian A Wilson, Jiang Zhu
Author Correction: Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines. Nature communications 13 (1) (2022)
Hejun Liu, Ian A Wilson
Protective neutralizing epitopes in SARS-CoV-2. Immunological reviews 310 (1) (2022)
Cherrelle Dacon, Courtney Tucker, Linghang Peng, Chang-Chun David Lee, Ting-Hui Lin, Meng Yuan, Yu Cong, Lingshu Wang, Lauren Purser, Jazmean K Williams, Chul-Woo Pyo, Ivan Košík, Zhe Hu, Ming Zhao, Divya Mohan, Andrew J R Cooper, Mary E Peterson, Jeff Skinner, Saurabh Dixit, Erin Kollins, Louis Huzella, Donna Perry, Russell Byrum, Sanae Lembirik, David Drawbaugh, Brett Eaton, Yi Zhang, Eun Sung Yang, Man Chen, Kwanyee Leung, Rona Singer Weinberg, Amarendra Pegu, Daniel E Geraghty, Edgar Davidson, Iyadh Douagi, Susan L Moir, Jonathan W Yewdell, Connie S Schmaljohn, Peter Dobbs Crompton, Michael R Holbrook, David Nemazee, John R Mascola, Ian A Wilson, Joshua Tan
Broadly neutralizing antibodies target the coronavirus fusion peptide. Science (New York, N.Y.) 377 (6607) (2022)
Huibin Lv, Ray T Y So, Qi Wen Teo, Meng Yuan, Hejun Liu, Chang-Chun David Lee, Garrick K Yip, Wilson W Ng, Ian A Wilson, Malik Peiris, Nicholas C Wu, Chris Ka Pun Mok
Neutralizing Antibody Response to Sarbecovirus Is Delayed in Sequential Heterologous Immunization. Viruses 14 (7) (2022)
Wan-Ting He, Meng Yuan, Sean Callaghan, Rami Musharrafieh, Sophie Ge Song, Murillo Silva, Nathan Beutler, Wen-Hsin Lee, Peter Yong, Jonathan L Torre, Mariane B Melo, Panpan Zhou, Fangzhu Zhao, Xueyong Zhu, Linghang Peng, Deli Huang, Fabio Anzanello, James Ricketts, Mara Parren, Elijah Garcia, Melissa Ferguson, William Rinaldi, Stephen A Rawlings, David Nemazee, Davey M Smith, Bryan Briney, Yana Safonova, Thomas F Rogers, Jennifer M Dan, Zeli Zhang, Daniela Weiskopf, Alessandro Sette, Shane Crotty, Darrell J Irvine, Andrew B Ward, Ian A Wilson, Dennis R Burton, Raiees Andrabi
Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques. Science translational medicine 14 (657) (2022)
Daniel Stadlbauer, Meagan McMahon, Hannah L Turner, Xueyong Zhu, Hongquan Wan, Juan Manuel Carreño, George O'Dell, Shirin Strohmeier, Zain Khalil, Marta Luksza, Harm van Bakel, Viviana Simon, Ali H Ellebedy, Ian A Wilson, Andrew B Ward, Florian Krammer
Antibodies targeting the neuraminidase active site inhibit influenza H3N2 viruses with an S245N glycosylation site. Nature communications 13 (1) (2022)
Daniel Stadlbauer, Meagan McMahon, Hannah L Turner, Xueyong Zhu, Hongquan Wan, Juan Manuel Carreño, George O'Dell, Shirin Strohmeier, Zain Khalil, Marta Luksza, Harm van Bakel, Viviana Simon, Ali H Ellebedy, Ian A Wilson, Andrew B Ward, Florian Krammer
Antibodies targeting the neuraminidase active site inhibit influenza H3N2 viruses with an S245N glycosylation site. Nature communications 13 (1) (2022)
Hejun Liu, Chengzi I Kaku, Ge Song, Meng Yuan, Raiees Andrabi, Dennis R Burton, Laura M Walker, Ian A Wilson
Human antibodies to SARS-CoV-2 with a recurring YYDRxG motif retain binding and neutralization to variants of concern including Omicron. Communications biology 5 (1) (2022)
S Momsen Reincke, Meng Yuan, Hans-Christian Kornau, Victor Max Corman, Scott van Hoof, Elisa Sánchez-Sendin, Melanie Ramberger, Wenli Yu, Yuanzi Hua, Henry Tien, Marie Luisa Schmidt, Tatjana Schwarz, Lara Maria Jeworowski, Sarah E Brandl, Helle Foverskov Rasmussen, Marie A Homeyer, Laura Stöffler, Martin Barner, Désirée Kunkel, Shufan Huo, Johannes Horler, Niels von Wardenburg, Inge Kroidl, Tabea M Eser, Andreas Wieser, Christof Geldmacher, Michael Hoelscher, Hannes Gänzer, Guenter Weiss, Dietmar Schmitz, Christian Drosten, Harald Prüss, Ian A Wilson, Jakob Kreye
SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies. Science (New York, N.Y.) 375 (6582) (2022)
Jonathan L Torre, Gabriel Ozorowski, Emanuele Andreano, Hejun Liu, Jeffrey Copps, Giulia Piccini, Lorena Donnici, Matteo Conti, Cyril Planchais, Delphine Planas, Noemi Manganaro, Elisa Pantano, Ida Paciello, Piero Pileri, Timothee Bruel, Emanuele Montomoli, Hugo Mouquet, Olivier Schwartz, Claudia Sala, Raffaele De Francesco, Ian A Wilson, Rino Rappuoli, Andrew B Ward
Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody. Proceedings of the National Academy of Sciences of the United States of America 119 (20) (2022)
Panpan Zhou, Meng Yuan, Sophie Ge Song, Nathan Beutler, Namir Shaabani, Deli Huang, Wan-Ting He, Xueyong Zhu, Sean Callaghan, Peter Yong, Fabio Anzanello, Linghang Peng, James Ricketts, Mara Parren, Elijah Garcia, Stephen A Rawlings, Davey M Smith, David Nemazee, John R Teijaro, Thomas F Rogers, Ian A Wilson, Dennis R Burton, Raiees Andrabi
A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection. Science translational medicine 14 (637) (2022)
Nathan Beutler, Tossapol Pholcharee, David Oyen, Yevel Flores-Garcia, Randall S MacGill, Elijah Garcia, Jaeson Santos Calla-Choque, Mara Parren, Linlin Yang, Wayne Volkmuth, Emily Locke, Jason A Regules, Sheetij Dutta, Daniel Emerling, Angela M Early, Daniel E Neafsey, Elizabeth A Winzeler, C Richter King, Fidel Zavala, Dennis R Burton, Ian A Wilson, Thomas F Rogers
A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum. PLoS pathogens 18 (3) (2022)
Daniel Stadlbauer, Meagan McMahon, Hannah L Turner, Xueyong Zhu, Hongquan Wan, Juan Manuel Carreño, George O'Dell, Shirin Strohmeier, Zain Khalil, Marta Luksza, Harm van Bakel, Viviana Simon, Ali H Ellebedy, Ian A Wilson, Andrew B Ward, Florian Krammer
Antibodies targeting the neuraminidase active site inhibit influenza H3N2 viruses with an S245N glycosylation site. Nature communications 13 (1) (2022)
Xueyong Zhu, Julianna Han, Weina Sun, Eduard Puente-Massaguer, Wenli Yu, Peter Palese, Florian Krammer, Andrew B Ward, Ian A Wilson
Influenza chimeric hemagglutinin structures in complex with broadly protective antibodies to the stem and trimer interface. Proceedings of the National Academy of Sciences of the United States of America 119 (21) (2022)
Daniel Stadlbauer, Meagan McMahon, Hannah L Turner, Xueyong Zhu, Hongquan Wan, Juan Manuel Carreño, George O'Dell, Shirin Strohmeier, Zain Khalil, Marta Luksza, Harm van Bakel, Viviana Simon, Ali H Ellebedy, Ian A Wilson, Andrew B Ward, Florian Krammer
Antibodies targeting the neuraminidase active site inhibit influenza H3N2 viruses with an S245N glycosylation site. Nature communications 13 (1) (2022)
Daniel Stadlbauer, Meagan McMahon, Hannah L Turner, Xueyong Zhu, Hongquan Wan, Juan Manuel Carreño, George O'Dell, Shirin Strohmeier, Zain Khalil, Marta Luksza, Harm van Bakel, Viviana Simon, Ali H Ellebedy, Ian A Wilson, Andrew B Ward, Florian Krammer
Antibodies targeting the neuraminidase active site inhibit influenza H3N2 viruses with an S245N glycosylation site. Nature communications 13 (1) (2022)
Meng Yuan, Xueyong Zhu, Wan-Ting He, Panpan Zhou, Chengzi I Kaku, Tazio Capozzola, Connie Y Zhu, Xinye Yu, Hejun Liu, Wenli Yu, Yuanzi Hua, Henry Tien, Linghang Peng, Ge Song, Christopher A Cottrell, William R Schief, David Nemazee, Laura M Walker, Raiees Andrabi, Dennis R Burton, Ian A Wilson
A broad and potent neutralization epitope in SARS-related coronaviruses. Proceedings of the National Academy of Sciences of the United States of America 119 (29) (2022)
Wan-Ting He, Rami Musharrafieh, Ge Song, Katharina Dueker, Longping V Tse, David R Martinez, Alexandra Schaefer, Sean Callaghan, Peter Yong, Nathan Beutler, Jonathan L Torre, Reid M Volk, Panpan Zhou, Meng Yuan, Hejun Liu, Fabio Anzanello, Tazio Capozzola, Mara Parren, Elijah Garcia, Stephen A Rawlings, Davey M Smith, Ian A Wilson, Yana Safonova, Andrew B Ward, Thomas F Rogers, Ralph S Baric, Lisa E Gralinski, Dennis R Burton, Raiees Andrabi
Targeted isolation of diverse human protective broadly neutralizing antibodies against SARS-like viruses. Nature immunology 23 (6) (2022)
Longxing Cao, Brian Coventry, Inna Goreshnik, Buwei Huang, William Sheffler, Joon Sung Park, Kevin M Jude, Iva Marković, Rameshwar U Kadam, Koen H G Verschueren, Kenneth Verstraete, Scott Thomas Russell Walsh, Nathaniel Bennett, Ashish Phal, Aerin Yang, Lisa Kozodoy, Michelle DeWitt, Lora K Picton, Lauren Miller, Eva-Maria Strauch, Nicholas D DeBouver, Allison Pires, Asim K Bera, Samer Halabiya, Bradley Hammerson, Wei Yang, Steffen Bernard, Lance J Stewart, Ian A Wilson, Hannele Ruohola-Baker, Joseph Schlessinger, Sangwon Lee, Savvas N Savvides, K Christopher Garcia, Julien S Baker
Design of protein-binding proteins from the target structure alone. Nature 605 (7910) (2022)
Jelle van Schooten, Elinaz Farokhi, Anna Schorcht, Tom L G M van den Kerkhof, Hongmei Gao, Patricia van der Woude, Judith A Burger, Tim G Rijkhold Meesters, Tom Bijl, Riham Ghalaiyini, Hannah L Turner, Jessica Dorning, Barbera D C van Schaik, Antoine H C van Kampen, Celia C LaBranche, Robyn L Stanfield, Devin Sok, David C Montefiori, Dennis R Burton, Michael S Seaman, Gabriel Ozorowski, Ian A Wilson, Rogier W Sanders, Andrew B Ward, Marit J VAN Gils
Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein. Nature communications 13 (1) (2022)
Chang-Chun David Lee, Yasunori Watanabe, Nicholas C Wu, Julianna Han, Sonu Kumar, Tossapol Pholcharee, Gemma E Seabright, Joel D Allen, Chih-Wei Lin, Ji-Rong Yang, Ming-Tsan Liu, Chung-Yi Wu, Andrew B Ward, Max Crispin, Ian A Wilson
A cross-neutralizing antibody between HIV-1 and influenza virus. PLoS pathogens 17 (3) (2021)
Meng Yuan, Deli Huang, Chang-Chun David Lee, Nicholas C Wu, Abigail M Jackson, Xueyong Zhu, Hejun Liu, Linghang Peng, Marit J VAN Gils, Rogier W Sanders, Dennis R Burton, S Momsen Reincke, Harald Prüss, Jakob Kreye, David Nemazee, Andrew B Ward, Ian A Wilson
Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants. Science (New York, N.Y.) 373 (6556) (2021)
Tossapol Pholcharee, David Oyen, Yevel Flores-Garcia, Gonzalo E González-Páez, Zhen Han, Katherine L Williams, Wayne Volkmuth, Daniel Emerling, Emily Locke, C Richter King, Fidel Zavala, Ian A Wilson
Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum. Nature communications 12 (1) (2021)
Xiaojie Shi, Yue Wan, Nan Wang, Jiangchao Xiang, Tao Wang, Xiaofeng Yang, Ju Wang, Xuxue Dong, Liang Dong, Lei Yan, Yu Li, Lili Liu, Shinchen Hou, Zhenwei Zhong, Ian A Wilson, Bei Yang, Guang Yang, Richard A Lerner
Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms. Nature communications 12 (1) (2021)
Paul-Albert Koenig, Hrishikesh Das, Hejun Liu, Beate M Kümmerer, Florian N Gohr, Lea-Marie Jenster, Lisa D J Schiffelers, Yonas M Tesfamariam, Miki Uchima, Jennifer Deborah Wuerth, Karl Gatterdam, Natalia Ruetalo, Maria H Christensen, Caroline I Fandrey, Sabine Normann, Jan M P Tödtmann, Steffen Pritzl, Leo Hanke, Jannik Boos, Meng Yuan, Xueyong Zhu, Jonathan L Schmid-Burgk, Hiroki Kato, Michael Schindler, Ian A Wilson, Matthias Geyer, Kerstin U Ludwig, B Martin Hällberg, Nicholas C Wu, Florian Ingo Schmidt
Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape. Science (New York, N.Y.) 371 (6530) (2021)
Timothy J C Tan, Meng Yuan, Kaylee Kuzelka, Gilberto C Padron, Jacob R Beal, Xin Chen, Yiquan Wang, Joel Rivera-Cardona, Xueyong Zhu, Beth M Stadtmueller, Christopher B Brooke, Ian A Wilson, Nicholas C Wu
Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain. Nature communications 12 (1) (2021)
Min Qiang, Peixiang Ma, Yu Li, Hejun Liu, Adam Harding, Chenyu Min, Fulian Wang, Lili Liu, Meng Yuan, Qun Ji, Pingdong Tao, Xiaojie Shi, Zhean Li, Teng Li, Xian Wang, Yu Zhang, Nicholas C Wu, Chang-Chun David Lee, Xueyong Zhu, Javier Gilbert Jaramillo, Chuyue Zhang, Abhishek Saxena, Xingxu Huang, Hou Wang, William S James, Raymond A Dwek, Ian A Wilson, Guang Yang, Richard A Lerner
Neutralizing Antibodies to SARS-CoV-2 Selected from a Human Antibody Library Constructed Decades Ago. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2021)
Rajasree Kalagiri, Robyn L Stanfield, Jill Meisenhelder, James J La Clair, Stephen R Fuhs, Ian A Wilson, Tony Hunter
Structural basis for differential recognition of phosphohistidine-containing peptides by 1-pHis and 3-pHis monoclonal antibodies. Proceedings of the National Academy of Sciences of the United States of America 118 (6) (2021)
Tanya R McKitrick, Steffen M Bernard, Alexander J Noll, Bernard C Collins, Christoffer Knak Goth, Alyssa M McQuillan, Jamie Heimburg-Molinaro, Brantley R Herrin, Ian A Wilson, Max D Cooper, Richard D Cummings
Novel lamprey antibody recognizes terminal sulfated galactose epitopes on mammalian glycoproteins. Communications biology 4 (1) (2021)
Joshua Tan, Hyeseon Cho, Tossapol Pholcharee, Lais S Pereira, Safiatou Doumbo, Didier Doumtabe, Barbara J Flynn, Arne Schön, Sachie Kanatani, Samantha O Aylor, David Oyen, Rachel Vistein, Lawrence T Wang, Marlon Dillon, Jeff Skinner, Mary E Peterson, Shanping Li, Azza H Idris, Alvaro Molina-Cruz, Ming Zhao, Lisa Renee Olano, Patricia J Lee, Alison Roth, Photini Sinnis, Carolina Barillas-Mury, Kassoum Kayentao, Aissata Ongoiba, Joseph R Francica, Boubacar Traore, Ian A Wilson, Robert A Seder, Peter Dobbs Crompton
Functional human IgA targets a conserved site on malaria sporozoites. Science translational medicine 13 (599) (2021)
Linling He, Anshul Chaudhary, Xiaohe Lin, Cindy Sou, Tanwee Alkutkar, Sonu Kumar, Timothy Ngo, Ezra Kosviner, Gabriel Ozorowski, Robyn L Stanfield, Andrew B Ward, Ian A Wilson, Jiang Zhu
Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines. Nature communications 12 (1) (2021)
Pauline Maisonnasse, Yoann Aldon, Aurélien Marc, Romain Marlin, Nathalie Bosquet, Natalia A Kuzmina, Alec W Freyn, Jonne L Snitselaar, Antonio Gonçalves, Tom G Caniels, Judith A Burger, Meliawati Poniman, Ilja Bontjer, Virginie Chesnais, Ségolène Diry, Anton Iershov, Adam J Ronk, Sonia Jangra, Raveen Rathnasinghe, Philip J M Brouwer, Tom P L Bijl, Jelle van Schooten, Mitch Brinkkemper, Hejun Liu, Meng Yuan, Chad E Mire, Mariëlle J van Breemen, Vanessa Contreras, Thibaut Naninck, Julien Lemaître, Nidhal Kahlaoui, Francis Relouzat, Catherine Chapon, Raphaël Ho Tsong Fang, Charlene McDanal, Mary Osei-Twum, Natalie St-Amant, Luc Gagnon, David C Montefiori, Ian A Wilson, Eric Ginoux, Godelieve J de Bree, Adolfo García-Sastre, Michael Schotsaert, Lynda Coughlan, Alexander Bukreyev, Sylvie van der Werf, Jeremie Guedj, Rogier W Sanders, Marit J van Gils, Roger Le Grand
COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models. Nature communications 12 (1) (2021)
Yiquan Wang, Meng Yuan, Jian Peng, Ian A Wilson, Nicholas C Wu
A large-scale systematic survey of SARS-CoV-2 antibodies reveals recurring molecular features. bioRxiv : the preprint server for biology (2021)
Linling He, Xiaohe Lin, Ying Wang, Ciril Abraham, Cindy Sou, Timothy Ngo, Yi Zhang, Ian A Wilson, Jiang Zhu
Single-component, self-assembling, protein nanoparticles presenting the receptor binding domain and stabilized spike as SARS-CoV-2 vaccine candidates. Science advances 7 (12) (2021)
Hyeseon Cho, Kristina Kay Gonzales-Wartz, Deli Huang, Meng Yuan, Mary E Peterson, Janie Liang, Nathan Beutler, Jonathan L Torre, Yu Cong, Elena Postnikova, Sandhya Bangaru, Chloe Adrienna Talana, Wei Shi, Eun Sung Yang, Yi Zhang, Kwanyee Leung, Lingshu Wang, Linghang Peng, Jeff Skinner, Shanping Li, Nicholas C Wu, Hejun Liu, Cherrelle Dacon, Thomas Moyer, Melanie Cohen, Ming Zhao, Frances Eun-Hyung Lee, Rona Singer Weinberg, Iyadh Douagi, Robin Gross, Connie S Schmaljohn, Amarendra Pegu, John R Mascola, Michael R Holbrook, David Nemazee, Thomas F Rogers, Andrew B Ward, Ian A Wilson, Peter Dobbs Crompton, Joshua Tan
Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern. Science translational medicine 13 (616) (2021)
Nicholas C Wu, Andrew J Thompson, Juhye M Lee, Wen Su, Britni M Arlian, Jia Xie, Richard A Lerner, Hui Ling Yen, Jesse D Bloom, Ian A Wilson
Different genetic barriers for resistance to HA stem antibodies in influenza H3 and H1 viruses. Science (New York, N.Y.) 368 (6497) (2020)
Yasunori Watanabe, Zachary T Berndsen, Jayna Raghwani, Gemma E Seabright, Joel D Allen, Oliver G Pybus, Jason S Mclellan, Ian A Wilson, Thomas A Bowden, Andrew B Ward, Max Crispin
Vulnerabilities in coronavirus glycan shields despite extensive glycosylation. Nature communications 11 (1) (2020)
Netanel Tzarum, Erick Giang, Rameshwar U Kadam, Fang Chen, Kenna Nagy, Elias H Augestad, Rodrigo Velázquez-Moctezuma, Zhen-Yong Keck, Yuanzi Hua, Robyn L Stanfield, Marlène Dreux, Jannick Prentoe, Steven K H Foung, Jens Bukh, Ian A Wilson, Mansun Law
An alternate conformation of HCV E2 neutralizing face as an additional vaccine target. Science advances 6 (30) (2020)
Thomas F Rogers, Fangzhu Zhao, Deli Huang, Nathan Beutler, Alison Burns, Wan-Ting He, Oliver Limbo, Chloe Smith, Sophie Ge Song, Jordan L Woehl, Linlin Yang, Robert K Abbott, Sean Callaghan, Elijah Garcia, Jonathan Hurtado, Mara Parren, Linghang Peng, Sydney I Ramirez, James Ricketts, Michael J Ricciardi, Stephen A Rawlings, Nicholas C Wu, Meng Yuan, Davey M Smith, David Nemazee, John R Teijaro, James E Voss, Ian A Wilson, Raiees Andrabi, Bryan Briney, Elise Landais, Devin Sok, Joseph G Jardine, Dennis R Burton
Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model. Science (New York, N.Y.) 369 (6506) (2020)
Meng Yuan, Hejun Liu, Nicholas C Wu, Chang-Chun David Lee, Xueyong Zhu, Fangzhu Zhao, Deli Huang, Wenli Yu, Yuanzi Hua, Henry Tien, Thomas F Rogers, Elise Landais, Devin Sok, Joseph G Jardine, Dennis R Burton, Ian A Wilson
Structural basis of a shared antibody response to SARS-CoV-2. Science (New York, N.Y.) 369 (6507) (2020)
Nicholas C Wu, Ian A Wilson
Structural Biology of Influenza Hemagglutinin: An Amaranthine Adventure. Viruses 12 (9) (2020)
Nicholas C Wu, Jakub Otwinowski, Andrew J Thompson, Corwin M Nycholat, Armita Nourmohammad, Ian A Wilson
Major antigenic site B of human influenza H3N2 viruses has an evolving local fitness landscape. Nature communications 11 (1) (2020)
Meng Yuan, Nicholas C Wu, Xueyong Zhu, Chang-Chun David Lee, Ray T Y So, Huibin Lv, Chris Ka Pun Mok, Ian A Wilson
A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV. Science (New York, N.Y.) 368 (6491) (2020)
David Oyen, Jonathan L Torre, Phillip C Aoto, Yevel Flores-Garcia, Špela Binter, Tossapol Pholcharee, Sean Carroll, Sini Reponen, Rachael Wash, Qi Liang, Franck Lemiale, Emily Locke, Allan Bradley, C Richter King, Daniel Emerling, Paul Kellam, Fidel Zavala, Andrew B Ward, Ian A Wilson
Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein. PLoS pathogens 16 (3) (2020)
Sonu Kumar, Bin Ju, Benjamin Shapero, Xiaohe Lin, Li Ren, Lei Zhang, Dan Li, Zehua Zhou, Yi Feng, Cindy Sou, Colin J Mann, Yanling Hao, Anita Sarkar, Jiali Hou, Christian Nunnally, Kunxue Hong, Shuo Wang, Xiangyang Ge, Bin Su, Elise Landais, Devin Sok, Michael B Zwick, Linling He, Jiang Zhu, Ian A Wilson, Yiming Shao
A VH1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite. Science advances 6 (38) (2020)
Bing Meng, Keke Lan, Jia Xie, Richard A Lerner, Ian A Wilson, Bei Yang
Inhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enteroviruses. Proceedings of the National Academy of Sciences of the United States of America 117 (24) (2020)
Robyn L Stanfield, Zachary T Berndsen, Ruiqi Huang, Devin Sok, Gabrielle F Warner, Jonathan L Torre, Dennis R Burton, Andrew B Ward, Ian A Wilson, Vaughn V Smider
Structural basis of broad HIV neutralization by a vaccine-induced cow antibody. Science advances 6 (22) (2020)
Nicholas C Wu, Meng Yuan, Hejun Liu, Chang-Chun David Lee, Xueyong Zhu, Sandhya Bangaru, Jonathan L Torre, Tom G Caniels, Philip J M Brouwer, Marit J VAN Gils, Rogier W Sanders, Andrew B Ward, Ian A Wilson
An alternative binding mode of IGHV3-53 antibodies to the SARS-CoV-2 receptor binding domain. bioRxiv : the preprint server for biology (2020)
Daniel Stadlbauer, Xueyong Zhu, Meagan McMahon, Jackson S Turner, Teddy J Wohlbold, Aaron J Schmitz, Shirin Strohmeier, Wenli Yu, Raffael Nachbagauer, Philip A Mudd, Ian A Wilson, Ali H Ellebedy, Florian Krammer
Broadly protective human antibodies that target the active site of influenza virus neuraminidase. Science (New York, N.Y.) 366 (6464) (2020)
Yao Yao, Rameshwar U Kadam, Chang-Chun David Lee, Jordan L Woehl, Nicholas C Wu, Xueyong Zhu, Seiya Kitamura, Ian A Wilson, Dennis W Wolan
An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen. Proceedings of the National Academy of Sciences of the United States of America 117 (31) (2020)
Linling He, Netanel Tzarum, Xiaohe Lin, Benjamin Shapero, Cindy Sou, Colin J Mann, Armando Stano, Lei Zhang, Kenna Nagy, Erick Giang, Mansun Law, Ian A Wilson, Jiang Zhu
Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines. Science advances 6 (16) (2020)
Nicholas C Wu, Meng Yuan, Sandhya Bangaru, Deli Huang, Xueyong Zhu, Chang-Chun David Lee, Hannah L Turner, Linghang Peng, Linlin Yang, Dennis R Burton, David Nemazee, Andrew B Ward, Ian A Wilson
A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody. PLoS pathogens 16 (12) (2020)
Lei Zhang, Adriana Irimia, Lingling He, Elise Landais, Kimmo Rantalainen, Daniel P Leaman, Thomas Vollbrecht, Armando Stano, Daniel I Sands, Arthur S Kim, null null, Pascal Poignard, Dennis R Burton, Ben Murrell, Andrew B Ward, Jiang Zhu, Ian A Wilson, Michael B Zwick
An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nature communications 10 (1) (2019)
Charles D Murin, Ian A Wilson, Andrew B Ward
Antibody responses to viral infections: a structural perspective across three different enveloped viruses. Nature microbiology 4 (5) (2019)
Maria J P van Dongen, Rameshwar U Kadam, Jarek Juraszek, Edward Lawson, Boerries Brandenburg, Frederike Schmitz, Wim B G Schepens, Bart Stoops, Harry A van Diepen, Mandy Jongeneelen, Chan Tang, Jan Vermond, Alida van Eijgen-Obregoso Real, Sven Blokland, Divita Garg, Wenli Yu, Wouter Goutier, Ellen Lanckacker, Jaco M Klap, Daniëlle C G Peeters, Jin Wu, Christophe Buyck, Tim H M Jonckers, Dirk Roymans, Peter Roevens, Ronald Vogels, Wouter Koudstaal, Robert H E Friesen, Pierre Raboisson, Dashyant Dhanak, Jaap Goudsmit, Ian A Wilson
A small-molecule fusion inhibitor of influenza virus is orally active in mice. Science (New York, N.Y.) 363 (6431) (2019)
Hannah L Turner, Jesper Pallesen, Shanshan Lang, Sandhya Bangaru, Sarah Urata, Sheng Li, Christopher A Cottrell, Charles A Bowman, James E Crowe, Ian A Wilson, Andrew B Ward
Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains. PLoS biology 17 (2) (2019)
Kwinten Sliepen, Byung Woo Han, Ilja Bontjer, Petra Mooij, Fernando Garces, Anna-Janina Behrens, Kimmo Rantalainen, Sonu Kumar, Anita Sarkar, Philip J M Brouwer, Yuanzi Hua, Monica Tolazzi, Edith Schermer, Jonathan L Torre, Gabriel Ozorowski, Patricia van der Woude, Alba Torrents de la Peña, Mariëlle J van Breemen, Juan Miguel Camacho-Sánchez, Judith A Burger, Max Medina-Ramírez, Nuria Gonzalez, Jose Alcami, Celia LaBranche, Gabriella Scarlatti, Marit J VAN Gils, Max Crispin, David C Montefiori, Andrew B Ward, Gerrit Koopman, John P Moore, Robin J Shattock, Willy M Bogers, Ian A Wilson, Rogier W Sanders
Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence. Nature communications 10 (1) (2019)
Senlian Hong, Yujie Shi, Nicholas C Wu, Geramie Grande, Lacey Douthit, Hua Wang, Wen Zhou, K Barry Sharpless, Ian A Wilson, Jia Xie, Peng Wu
Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification. Nature communications 10 (1) (2019)
Colin Havenar-Daughton, Anita Sarkar, Daniel W Kulp, Laura Toy, Xiaozhen Hu, Isaiah Deresa, Oleksandr Kalyuzhniy, Kirti Kaushik, Amit A Upadhyay, Sergey Menis, Elise Landais, Liwei Cao, Jolene K Diedrich, Sonu Kumar, Torben Schiffner, Samantha M Reiss, Grégory Seumois, John Yates Iii, James C Paulson, Steven E Bosinger, Ian A Wilson, William R Schief, Shane Crotty
The human naive B cell repertoire contains distinct subclasses for a germline-targeting HIV-1 vaccine immunogen. Science translational medicine 10 (448) (2019)
Jon M Steichen, Ying-Cing Lin, Colin Havenar-Daughton, Simone Pecetta, Gabriel Ozorowski, Jordan R Willis, Laura Toy, Devin Sok, Alessia Liguori, Sven Kratochvil, Jonathan L Torre, Oleksandr Kalyuzhniy, Eleonora Melzi, Daniel W Kulp, Sebastian Rämisch, Xiaozhen Hu, Steffen M Bernard, Erik Georgeson, Nicole Phelps, Yumiko Adachi, Michael Kubitz, Elise Landais, Jeffrey Umotoy, Amanda M Robinson, Bryan Briney, Ian A Wilson, Dennis R Burton, Andrew B Ward, Shane Crotty, Facundo D Batista, William R Schief
A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses. Science (New York, N.Y.) 366 (6470) (2019)
Qingping Xu, Matthew Biancalana, Joanna C Grant, Hsiu-Ju Chiu, Lukasz Jaroszewski, Mark W Knuth, Scott A Lesley, Adam Godzik, Marc-André Elsliger, Ashley M Deacon, Ian A Wilson
Structures of single-layer β-sheet proteins evolved from β-hairpin repeats. Protein science : a publication of the Protein Society 28 (9) (2019)
Sonu Kumar, Anita Sarkar, Pavel Pugach, Rogier W Sanders, John P Moore, Andrew B Ward, Ian A Wilson
Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide. Nature communications 10 (1) (2019)
Netanel Tzarum, Erick Giang, Leopold Kong, Linling He, Jannick Prentoe, Elias H Augestad, Yuanzi Hua, Shaun Castillo, Georg M Lauer, Jens Bukh, Jiang Zhu, Ian A Wilson, Mansun Law
Genetic and structural insights into broad neutralization of hepatitis C virus by human VH1-69 antibodies. Science advances 5 (1) (2019)
Phillip C Aoto, Robyn L Stanfield, Ian A Wilson, H Jane Dyson, Peter E Wright
A Dynamic Switch in Inactive p38γ Leads to an Excited State on the Pathway to an Active Kinase. Biochemistry 58 (51) (2019)
Shuai Xia, Lei Yan, Wei Xu, Anurodh Shankar Agrawal, Abdullah Algaissi, Chien-Te K Tseng, Qian Wang, Lanying Du, Wenjie Tan, Ian A Wilson, Shibo Jiang, Bei Yang, Lu Lu
A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike. Science advances 5 (4) (2019)
Linling He, Sonu Kumar, Joel D Allen, Deli Huang, Xiaohe Lin, Colin J Mann, Karen L Saye-Francisco, Jeffrey Copps, Anita Sarkar, Gabrielle S Blizard, Gabriel Ozorowski, Devin Sok, Max Crispin, Andrew B Ward, David Nemazee, Dennis R Burton, Ian A Wilson, Jiang Zhu
HIV-1 vaccine design through minimizing envelope metastability. Science advances 4 (11) (2018)
Nicholas C Wu, Andrew J Thompson, Jia Xie, Chih-Wei Lin, Corwin M Nycholat, Xueyong Zhu, Richard A Lerner, James C Paulson, Ian A Wilson
A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nature communications 9 (1) (2018)
Nicholas C Wu, Ian A Wilson
Structural insights into the design of novel anti-influenza therapies. Nature structural & molecular biology 25 (2) (2018)
David Oyen, Jonathan L Torre, Christopher A Cottrell, C Richter King, Ian A Wilson, Andrew B Ward
Cryo-EM structure of P. falciparum circumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts. Science advances 4 (10) (2018)
Anita Sarkar, Shridhar Bale, Anna-Janina Behrens, Sonu Kumar, Shailendra Kumar Sharma, Natalia de Val, Jesper Pallesen, Adriana Irimia, Devan C Diwanji, Robyn L Stanfield, Andrew B Ward, Max Crispin, Richard T Wyatt, Ian A Wilson
Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer. Nature communications 9 (1) (2018)
Per Johan Klasse, Thomas J Ketas, Christopher A Cottrell, Gabriel Ozorowski, Gargi Debnath, Diawoye Camara, Erik Francomano, Pavel Pugach, Rajesh P Ringe, Celia C LaBranche, Marit J VAN Gils, Christine A Bricault, Dan H Barouch, Shane Crotty, Guido Silvestri, Sudhir Kasturi, Bali Pulendran, Ian A Wilson, David C Montefiori, Rogier W Sanders, Andrew B Ward, John P Moore
Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques. PLoS pathogens 14 (2) (2018)
Robert P de Vries, Netanel Tzarum, Wenjie Peng, Andrew J Thompson, Iresha N Ambepitiya Wickramasinghe, Alba T Torrents de la Pena, Marielle J van Breemen, Kim M Bouwman, Xueyong Zhu, Ryan McBride, Wenli Yu, Rogier W Sanders, Monique H Verheije, Ian A Wilson, James C Paulson
A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human-type receptors. EMBO molecular medicine 9 (9) (2018)
Joshua Tan, Brandon K Sack, David Oyen, Isabelle Zenklusen, Luca Piccoli, Sonia Barbieri, Mathilde Foglierini, Chiara Silacci Fregni, Jessica Marcandalli, Said Jongo, Salim Abdulla, Laurent Perez, Giampietro Corradin, Luca Varani, Federica Sallusto, Betty Kim Lee Sim, Stephen L Hoffman, Stefan H I Kappe, Claudia A Daubenberger, Ian A Wilson, Antonio Lanzavecchia
A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein. Nature medicine 24 (4) (2018)
Nick Stub Laursen, Robert H E Friesen, Xueyong Zhu, Mandy Jongeneelen, Sven Blokland, Jan Vermond, Alida van Eijgen, Chan Tang, Harry A van Diepen, Galina Obmolova, Marijn van der Neut Kolfschoten, David Zuijdgeest, Roel Straetemans, Ryan M B Hoffman, Travis Nieusma, Jesper Pallesen, Hannah L Turner, Steffen M Bernard, Andrew B Ward, Jinquan Luo, Leo L M Poon, Anna P Tretiakova, James M Wilson, Maria P Limberis, Ronald Vogels, Boerries Brandenburg, Joost A Kolkman, Ian A Wilson
Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin. Science (New York, N.Y.) 362 (6414) (2018)
Sandhya Bangaru, Heng Zhang, Iuliia M Gilchuk, Thomas G Voss, Ryan P Irving, Pavlo Gilchuk, Pranathi Matta, Xueyong Zhu, Shanshan Lang, Travis Nieusma, Juergen A Richt, Randy A Albrecht, Hillary A Vanderven, Robin Bombardi, Stephen J Kent, Andrew B Ward, Ian A Wilson, James E Crowe
A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA. Nature communications 9 (1) (2018)
Nicholas C Wu, Geramie Grande, Hannah L Turner, Andrew B Ward, Jia Xie, Richard A Lerner, Ian A Wilson
In vitro evolution of an influenza broadly neutralizing antibody is modulated by hemagglutinin receptor specificity. Nature communications 8 (2017)
Xiaozhou Luo, Guangsen Fu, Rongsheng E Wang, Xueyong Zhu, Claudio Zambaldo, Renhe Liu, Tao Liu, Xiaoxuan Lyu, Jintang Du, Weimin Xuan, Anzhi Yao, Sean A Reed, Mingchao Kang, Yuhan Zhang, Hui Guo, Chunhui Huang, Peng-Yu Yang, Ian A Wilson, Peter G Schultz, Feng Wang
Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria. Nature chemical biology 13 (8) (2017)
Adriana Irimia, Andreia M Serra, Anita Sarkar, Ronald Jacak, Oleksandr Kalyuzhniy, Devin Sok, Karen L Saye-Francisco, Torben Schiffner, Ryan Tingle, Michael Kubitz, Yumiko Adachi, Robyn L Stanfield, Marc C Deller, Dennis R Burton, William R Schief, Ian A Wilson
Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design. PLoS pathogens 13 (2) (2017)
Eva-Maria Strauch, Steffen M Bernard, David La, Alan J Bohn, Peter S Lee, Caitlin E Anderson, Travis Nieusma, Carly A Holstein, Natalie K Garcia, Kathryn A Hooper, Rashmi Ravichandran, Jorgen W Nelson, William Sheffler, Jesse D Bloom, Kelly K Lee, Andrew B Ward, Paul Yager, Deborah H Fuller, Ian A Wilson, David Baker
Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site. Nature biotechnology 35 (7) (2017)
Kathrin Koch, Sarah Kalusche, Jonathan L Torres, Robyn L Stanfield, Welbeck Danquah, Kamal Khazanehdari, Hagen von Briesen, Eric R Geertsma, Ian A Wilson, Ulrich Wernery, Friedrich Koch-Nolte, Andrew B Ward, Ursula Dietrich
Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers. Scientific reports 7 (1) (2017)
Ralph Pantophlet, Nino Trattnig, Sasha Murrell, Naiomi Lu, Dennis Chau, Caitlin Rempel, Ian A Wilson, Paul Kosma
Bacterially derived synthetic mimetics of mammalian oligomannose prime antibody responses that neutralize HIV infectivity. Nature communications 8 (1) (2017)
Radhika Gopal, Kelli Jackson, Netanel Tzarum, Leopold Kong, Andrew Ettenger, Johnathan Guest, Jennifer M Pfaff, Trevor Barnes, Andrew Honda, Erick Giang, Edgar Davidson, Ian A Wilson, Benjamin J Doranz, Mansun Law
Probing the antigenicity of hepatitis C virus envelope glycoprotein complex by high-throughput mutagenesis. PLoS pathogens 13 (12) (2017)
Rameshwar U Kadam, Jarek Juraszek, Boerries Brandenburg, Christophe Buyck, Wim B G Schepens, Bart Kesteleyn, Bart Stoops, Rob J Vreeken, Jan Vermond, Wouter Goutier, Chan Tang, Ronald Vogels, Robert H E Friesen, Jaap Goudsmit, Maria J P van Dongen, Ian A Wilson
Potent peptidic fusion inhibitors of influenza virus. Science (New York, N.Y.) 358 (6362) (2017)