Jean-Philippe Julien

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 28

Top Venues

Nature communications

EMBO molecular medicine

eLife

Antibodies (Basel, Switzerland)

University of Toronto

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Toronto Sep 01 2014

Canada

Assistant Professor :: Biochemsitry and Immunology

The Hospital for Sick Children Sep 01 2014

Canada

Scientist :: Molecular Medicine

Publications

Audrey Kassardjian, Danton Ivanochko, Brian Barber, Arif Jetha, Jean-Philippe Julien
Humanization of Pan-HLA-DR mAb 44H10 Hinges on Critical Residues in the Antibody Framework. Antibodies (Basel, Switzerland) 13 (3) (2024)
Audrey Kassardjian, Danton Ivanochko, Brian Barber, Arif Jetha, Jean-Philippe Julien
Humanization of Pan-HLA-DR mAb 44H10 Hinges on Critical Residues in the Antibody Framework. Antibodies (Basel, Switzerland) 13 (3) (2024)
Prabhu S Arunachalam, NaYoung Ha, S Moses Dennison, Rachel L Spreng, Kelly E Seaton, Peng Xiao, Yupeng Feng, Veronika I Zarnitsyna, Dmitri Kazmin, Mengyun Hu, Jordan M Santagata, Xia Xie, Kenneth A Rogers, Lisa M Shirreff, Claire Chottin, Alexandra J Spencer, Sheetij Dutta, Katherine Prieto, Jean-Philippe Julien, Mark Tomai, Christopher B Fox, François J Villinger, Adrian V S Hill, Georgia D Tomaras, Bali Pulendran
A comparative immunological assessment of multiple clinical-stage adjuvants for the R21 malaria vaccine in nonhuman primates. Science translational medicine 16 (758) (2024)
Julia Ludwig, Stephen W Scally, Giulia Costa, Sandro Hoffmann, Rajagopal Murugan, Jana Lossin, Katherine Prieto, Anna Obraztcova, Nina Lobeto, Blandine Franke-Fayard, Chris J Janse, Celia Lebas, Nicolas Collin, Spela Binter, Paul Kellam, Elena A Levashina, Hedda Wardemann, Jean-Philippe Julien
Author Correction: Glycosylated nanoparticle-based PfCSP vaccine confers long-lasting antibody responses and sterile protection in mouse malaria model. NPJ vaccines 8 (1) (2023)
Opeyemi Ernest Oludada, Giulia Costa, Clare Burn Aschner, Anna S Obraztsova, Katherine Prieto, Caterina Canetta, Stephen L Hoffman, Peter G Kremsner, Benjamin Mordmüller, Rajagopal Murugan, Jean-Philippe Julien, Elena A Levashina, Hedda Wardemann
Molecular and functional properties of human Plasmodium falciparum CSP C-terminus antibodies. EMBO molecular medicine (2023)
Clare Burn Aschner, Krithika Muthuraman, Iga Kucharska, Hong Cui, Katherine Prieto, Manoj S Nair, Maple Wang, Yaoxing Huang, Natasha Christie-Holmes, Betty Poon, Jessica Lam, Azmiri Sultana, Robert Kozak, Samira Mubareka, John L Rubinstein, Edurne Rujas, Bebhinn Treanor, David D Ho, Arif Jetha, Jean-Philippe Julien
A multi-specific, multi-affinity antibody platform neutralizes sarbecoviruses and confers protection against SARS-CoV-2 in vivo. Science translational medicine 15 (697) (2023)
Julia Ludwig, Stephen W Scally, Giulia Costa, Sandro Hoffmann, Rajagopal Murugan, Jana Lossin, Katherine Prieto, Anna Obraztcova, Nina Lobeto, Blandine Franke-Fayard, Chris J Janse, Celia Lebas, Nicolas Collin, Spela Binter, Paul Kellam, Elena A Levashina, Hedda Wardemann, Jean-Philippe Julien
Glycosylated nanoparticle-based PfCSP vaccine confers long-lasting antibody responses and sterile protection in mouse malaria model. NPJ vaccines 8 (1) (2023)
Opeyemi Ernest Oludada, Giulia Costa, Clare Burn Aschner, Anna S Obraztsova, Katherine Prieto, Caterina Canetta, Stephen L Hoffman, Peter G Kremsner, Benjamin Mordmüller, Rajagopal Murugan, Jean-Philippe Julien, Elena A Levashina, Hedda Wardemann
Molecular and functional properties of human Plasmodium falciparum CSP C-terminus antibodies. EMBO molecular medicine (2023)
Opeyemi Ernest Oludada, Giulia Costa, Clare Burn Aschner, Anna S Obraztsova, Katherine Prieto, Caterina Canetta, Stephen L Hoffman, Peter G Kremsner, Benjamin Mordmüller, Rajagopal Murugan, Jean-Philippe Julien, Elena A Levashina, Hedda Wardemann
Molecular and functional properties of human Plasmodium falciparum CSP C-terminus antibodies. EMBO molecular medicine (2023)
Edurne Rujas, Hong Cui, Jonathan Burnie, Clare Burn Aschner, Tiantian Zhao, Sara Insausti, Krithika Muthuraman, Anthony Semesi, Jasper Ophel, Jose L Nieva, Michael S Seaman, Christina Guzzo, Bebhinn Treanor, Jean-Philippe Julien
Engineering pan-HIV-1 neutralization potency through multispecific antibody avidity. Proceedings of the National Academy of Sciences of the United States of America 119 (4) (2022)
Robin Hallett, Ester Bonfill-Teixidor, Raffaella Iurlaro, Alexandra Arias, Swetha Raman, Peter E Bayliss, Olga Egorova, Almudena Neva-Alejo, A J Robert McGray, Esther Lau, Alexandre Bosch, Melissa Beilschmidt, Dorothea Maetzel, Johan Fransson, Isabel Huber-Ruano, Judit Anido, Jean-Philippe Julien, Patricia A Giblin, Joan Seoane
Therapeutic targeting of LIF overcomes macrophage mediated immunosuppression of the local tumor microenvironment. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Iga Kucharska, Špela Binter, Rajagopal Murugan, Stephen W Scally, Julia Ludwig, Katherine Prieto, Elaine Thai, Giulia Costa, Kan Li, Gillian Q Horn, Yevel Flores-Garcia, Alexandre Bosch, Taylor Sicard, John L Rubinstein, Fidel Zavala, S Moses Dennison, Georgia D Tomaras, Elena A Levashina, Paul Kellam, Hedda Wardemann, Jean-Philippe Julien
High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire. PLoS pathogens 18 (11) (2022)
Iga Kucharska, Lamia Hossain, Danton Ivanochko, Qiren Yang, John L Rubinstein, Régis Pomès, Jean-Philippe Julien
Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats. eLife 11 (2022)
Edurne Rujas, Iga Kucharska, Yong Zi Tan, Samir Benlekbir, Hong Cui, Tiantian Zhao, Gregory A Wasney, Patrick Budylowski, Furkan Guvenc, Jocelyn C Newton, Taylor Sicard, Anthony Semesi, Krithika Muthuraman, Amy Nouanesengsy, Clare Burn Aschner, Katherine Prieto, Stephanie A Bueler, Sawsan Youssef, Sindy Liao-Chan, Jacob Glanville, Natasha Christie-Holmes, Samira Mubareka, Scott D Gray-Owen, John L Rubinstein, Bebhinn Treanor, Jean-Philippe Julien
Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers. Nature communications 12 (1) (2021)
Moustafa T Mabrouk, Kevin Chiem, Edurne Rujas, Wei-Chiao Huang, Dushyant Jahagirdar, Breandan Quinn, Meera Surendran Nair, Ruth H Nissly, Victoria S Cavener, Nina R Boyle, Ty A Sornberger, Suresh V Kuchipudi, Joaquin Ortega, Jean-Philippe Julien, Luis Martinez-Sobrido, Jonathan F Lovell
Lyophilized, thermostable Spike or RBD immunogenic liposomes induce protective immunity against SARS-CoV-2 in mice. Science advances 7 (49) (2021)
Emily Rodrigues, Jaesoo Jung, Heajin Park, Caleb Loo, Sepideh Soukhtehzari, Elena N Kitova, Fahima Mozaneh, Gour Daskhan, Edward N Schmidt, Vivian Aghanya, Susmita Sarkar, Laura Streith, Chris D St Laurent, Linh Nguyen, Jean-Philippe Julien, Lori J West, Karla C Williams, John S Klassen, Matthew Scott Macauley
A versatile soluble siglec scaffold for sensitive and quantitative detection of glycan ligands. Nature communications 11 (1) (2020)
Rajagopal Murugan, Stephen W Scally, Giulia Costa, Ghulam Mustafa, Elaine Thai, Tizian Decker, Alexandre Bosch, Katherine Prieto, Elena A Levashina, Jean-Philippe Julien, Hedda Wardemann
Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs. Nature medicine 26 (7) (2020)
Fabian Sesterhenn, Che Yang, Jaume Bonet, Johannes T Cramer, Xiaolin Wen, Yimeng Wang, Chi-I Chiang, Luciano Andrés Abriata, Iga Kucharska, Giacomo Castoro, Sabrina S Vollers, Marie Galloux, Elie Dheilly, Stéphane Rosset, Patricia Corthésy, Sandrine Georgeon, Mélanie Villard, Charles-Adrien Richard, Delphyne Descamps, Teresa Delgado, Elisa Oricchio, Marie-Anne Rameix-Welti, Vicente Más, Sean Ervin, Jean-François Eleouet, Sabine Riffault, John T Bates, Jean-Philippe Julien, Yuxing Li, Theodore S Jardetzky, Thomas Krey, Bruno E Correia
De novo protein design enables the precise induction of RSV-neutralizing antibodies. Science (New York, N.Y.) 368 (6492) (2020)
Iga Kucharska, Elaine Thai, Ananya Srivastava, John L Rubinstein, Régis Pomès, Jean-Philippe Julien
Structural ordering of the Plasmodium berghei circumsporozoite protein repeats by inhibitory antibody 3D11. eLife 9 (2020)
Edurne Rujas, Hong Cui, Taylor Sicard, Anthony Semesi, Jean-Philippe Julien
Structural characterization of the ICOS/ICOS-L immune complex reveals high molecular mimicry by therapeutic antibodies. Nature communications 11 (1) (2020)
Taylor Sicard, Audrey Kassardjian, Jean-Philippe Julien
B cell targeting by molecular adjuvants for enhanced immunogenicity. Expert review of vaccines 19 (11) (2020)
Brandon McLeod, Kazutoyo Miura, Stephen W Scally, Alexandre Bosch, Ngan Nguyen, Hanjun Shin, Dongkyoon Kim, Wayne Volkmuth, Sebastian Rämisch, Jessica A Chichester, Stephen Streatfield, Colleen Woods, William R Schief, Daniel Emerling, C Richter King, Jean-Philippe Julien
Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25. Nature communications 10 (1) (2019)
Jean-Philippe Julien, Hedda Wardemann
Antibodies against Plasmodium falciparum malaria at the molecular level. Nature reviews. Immunology 19 (12) (2019)
Swetha Raman, Melissa Beilschmidt, Minh To, Kevin Lin, Francine Lui, Yazen Jmeian, Mark Ng, Minerva Fernandez, Ying Fu, Keith Mascall, Alejandro Duque, Xiaowei Wang, Guohua Pan, Stephane Angers, Jason Moffat, Sachdev S Sidhu, Jeanne Magram, Angus M Sinclair, Johan Fransson, Jean-Philippe Julien
Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies. Proceedings of the National Academy of Sciences of the United States of America 116 (14) (2019)
Pablo Carravilla, Jakub Chojnacki, Edurne Rujas, Sara Insausti, Eneko Largo, Dominic Waithe, Beatriz Apellaniz, Taylor Sicard, Jean-Philippe Julien, Christian Eggeling, José L Nieva
Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions. Nature communications 10 (1) (2019)
Prasun Kundu, Anthony Semesi, Matthijs M Jore, Merribeth J Morin, Virginia L Price, Alice Liang, Jingxing Li, Kazutoyo Miura, Robert W Sauerwein, C Richter King, Jean-Philippe Julien
Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45. Nature communications 9 (1) (2018)
Katharina Imkeller, Stephen W Scally, Alexandre Bosch, Gemma Pidelaserra Martí, Giulia Costa, Gianna Triller, Rajagopal Murugan, Valerio Renna, Hassan Jumaa, Peter G Kremsner, Betty Kim Lee Sim, Stephen L Hoffman, Benjamin Mordmüller, Elena A Levashina, Jean-Philippe Julien, Hedda Wardemann
Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope. Science (New York, N.Y.) 360 (6395) (2018)
Stephen W Scally, Rajagopal Murugan, Alexandre Bosch, Gianna Triller, Giulia Costa, Benjamin Mordmüller, Peter G Kremsner, B Kim Lee Sim, Stephen L Hoffman, Elena A Levashina, Hedda Wardemann, Jean-Philippe Julien
Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection. The Journal of experimental medicine 215 (1) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Jean-Philippe Julien