Beat Ernst

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 24

Top Topics

Urinary Tract Infection

Molecular Docking

Binding Protein

Regulatory T Cells

Top Venues

Journal of medicinal chemistry

Chemistry (Weinheim an der Bergstrasse, Germany)

Journal of the American Chemical Society

This page only lists publications with an associated author ORCID identifier.

Publications

Dilara D Nemli, Xiaohua Jiang, Roman P Jakob, Laura Muñoz Gloder, Oliver Schwardt, Said Rabbani, Timm Maier, Beat Ernst, Jonathan Cramer
Thermodynamics-Guided Design Reveals a Cooperative Hydrogen Bond in DC-SIGN-targeted Glycomimetics. Journal of medicinal chemistry 67 (16) (2024)
Dilara D Nemli, Xiaohua Jiang, Roman P Jakob, Laura Muñoz Gloder, Oliver Schwardt, Said Rabbani, Timm Maier, Beat Ernst, Jonathan Cramer
Thermodynamics-Guided Design Reveals a Cooperative Hydrogen Bond in DC-SIGN-targeted Glycomimetics. Journal of medicinal chemistry (2024)
Dilara D Nemli, Xiaohua Jiang, Roman P Jakob, Laura Muñoz Gloder, Oliver Schwardt, Said Rabbani, Timm Maier, Beat Ernst, Jonathan Cramer
Thermodynamics-Guided Design Reveals a Cooperative Hydrogen Bond in DC-SIGN-targeted Glycomimetics. Journal of medicinal chemistry 67 (16) (2024)
Jonathan Cramer, Xiaohua Jiang, Butrint Aliu, Beat Ernst
Combating DC-SIGN-mediated SARS-CoV-2 dissemination by glycan-mimicking polymers. Archiv der Pharmazie (2023)
Tiago Bozzola, Mariafrancesca Scalise, Christer U Larsson, Michael C Newton-Vesty, Caterina Rovegno, Ankita Mitra, Jonathan Cramer, Weixiao Yuan Wahlgren, Partha Radhakrishnan Santhakumari, Richard E Johnsson, Oliver Schwardt, Beat Ernst, Rosmarie Friemann, Renwick C J Dobson, Cesare Indiveri, Jenny Schelin, Ulf J Nilsson, Ulf Ellervik
Sialic Acid Derivatives Inhibit SiaT Transporters and Delay Bacterial Growth. ACS chemical biology 17 (7) (2022)
Jonathan Cramer, Butrint Aliu, Xiaohua Jiang, Timothy Sharpe, Lijuan Pang, Adrian Hadorn, Said Rabbani, Beat Ernst
Poly-l-lysine Glycoconjugates Inhibit DC-SIGN-mediated Attachment of Pandemic Viruses. ChemMedChem 16 (15) (2021)
Chao Gao, Kathrin Stavenhagen, Barbara Eckmair, Tanya R McKitrick, Akul Y Mehta, Yasuyuki Matsumoto, Alyssa M McQuillan, Melinda S Hanes, Deniz Eris, Kelly J Baker, Nan Jia, Mohui Wei, Jamie Heimburg-Molinaro, Beat Ernst, Richard D Cummings
Differential recognition of oligomannose isomers by glycan-binding proteins involved in innate and adaptive immunity. Science advances 7 (24) (2021)
Robert Wawrzinek, Eike-Christian Wamhoff, Jonathan Lefebre, Mareike Rentzsch, Gunnar Bachem, Gary Domeniconi, Jessica Schulze, Felix F Fuchsberger, Hengxi Zhang, Carlos Modenutti, Lennart Schnirch, Marcelo A Marti, Oliver Schwardt, Maria Bräutigam, Mónica Guberman, Dirk Hauck, Peter H Seeberger, Oliver Seitz, Alexander Titz, Beat Ernst, Christoph Rademacher
A Remote Secondary Binding Pocket Promotes Heteromultivalent Targeting of DC-SIGN. Journal of the American Chemical Society 143 (45) (2021)
Jonathan Cramer, Adem Lakkaichi, Butrint Aliu, Roman P Jakob, Sebastian Klein, Ivan Cattaneo, Xiaohua Jiang, Said Rabbani, Oliver Schwardt, Gert Zimmer, Matias Ciancaglini, Tiago Abreu Mota, Timm Maier, Beat Ernst
Sweet Drugs for Bad Bugs: A Glycomimetic Strategy against the DC-SIGN-Mediated Dissemination of SARS-CoV-2. Journal of the American Chemical Society 143 (42) (2021)
Philipp Dätwyler, Xiaohua Jiang, Beatrice Wagner, Norbert Varga, Tobias Mühlethaler, Katja Hostettler, Said Rabbani, Oliver Schwardt, Beat Ernst
Prodrugs of E-selectin Antagonists with Enhanced Pharmacokinetic Properties. ChemMedChem (2021)
Ana M de Matos, M Teresa Blázquez-Sánchez, Andreia Bento-Oliveira, Rodrigo F M de Almeida, Rafael Santana Nunes, Pedro E M Lopes, Miguel Machuqueiro, Joana S Cristóvão, Cláudio M Gomes, Cleide S Souza, Imane G El Idrissi, Nicola Antonio Colabufo, Ana Diniz, Filipa Marcelo, M Conceição Oliveira, Óscar López, José G Fernández-Bolaños, Philipp Dätwyler, Beat Ernst, Ke Ning, Claire Garwood, Beining Chen, Amélia Pilar Rauter
Glucosylpolyphenols as Inhibitors of Aβ-Induced Fyn Kinase Activation and Tau Phosphorylation: Synthesis, Membrane Permeability, and Exploratory Target Assessment within the Scope of Type 2 Diabetes and Alzheimer's Disease. Journal of medicinal chemistry 63 (20) (2020)
Blijke S Kroezen, Gabriele Conti, Benedetta Girardi, Jonathan Cramer, Xiaohua Jiang, Said Rabbani, Jennifer Müller, Maja Kokot, Enrico Luisoni, Daniel Ricklin, Oliver Schwardt, Beat Ernst
A Potent Mimetic of the Siglec-8 Ligand 6'-Sulfo-Sialyl Lewisx. ChemMedChem 15 (18) (2020)
Jonathan Cramer, Xiaohua Jiang, Wojciech Schönemann, Marleen Silbermann, Pascal Zihlmann, Stefan Siegrist, Brigitte Fiege, Roman Peter Jakob, Said Rabbani, Timm Maier, Beat Ernst
Enhancing the enthalpic contribution of hydrogen bonds by solvent shielding. RSC chemical biology 1 (4) (2020)
Butrint Aliu, Delphine Demeestere, Emilie Seydoux, José Boucraut, Emilien Delmont, Alexandre Brodovitch, Thomas Oberholzer, Shahram Attarian, Marie Théaudin, Pinelopi Tsouni, Thierry Kuntzer, Tobias Derfuss, Andreas J Steck, Beat Ernst, Ruben Herrendorff, Pascal Hänggi
Selective inhibition of anti-MAG IgM autoantibody binding to myelin by an antigen-specific glycopolymer. Journal of neurochemistry 154 (5) (2020)
Jonathan Cramer, Christoph P Sager, Beat Ernst
Hydroxyl Groups in Synthetic and Natural-Product-Derived Therapeutics: A Perspective on a Common Functional Group. Journal of medicinal chemistry 62 (20) (2019)
Wojciech Schönemann, Jonathan Cramer, Tobias Mühlethaler, Brigitte Fiege, Marleen Silbermann, Said Rabbani, Philipp Dätwyler, Pascal Zihlmann, Roman P Jakob, Christoph P Sager, Martin Smieško, Oliver Schwardt, Timm Maier, Beat Ernst
Improvement of Aglycone π-Stacking Yields Nanomolar to Sub-nanomolar FimH Antagonists. ChemMedChem 14 (7) (2019)
Maximilian M Sauer, Roman P Jakob, Thomas Luber, Fabia Canonica, Giulio Navarra, Beat Ernst, Carlo Unverzagt, Timm Maier, Rudi Glockshuber
Binding of the Bacterial Adhesin FimH to Its Natural, Multivalent High-Mannose Type Glycan Targets. Journal of the American Chemical Society 141 (2) (2018)
Priska Frei, Rachel Hevey, Beat Ernst
Dynamic Combinatorial Chemistry: A New Methodology Comes of Age. Chemistry (Weinheim an der Bergstrasse, Germany) 25 (1) (2018)
Tianlin Guo, Philipp Dätwyler, Ekaterina Demina, Michele R Richards, Peng Ge, Chunxia Zou, Ruixiang Zheng, Anne Fougerat, Alexey V Pshezhetsky, Beat Ernst, Christopher W Cairo
Selective Inhibitors of Human Neuraminidase 3. Journal of medicinal chemistry 61 (5) (2018)
Pascal Zihlmann, Marleen Silbermann, Timothy Sharpe, Xiaohua Jiang, Tobias Mühlethaler, Roman P Jakob, Said Rabbani, Christoph P Sager, Priska Frei, Lijuan Pang, Timm Maier, Beat Ernst
KinITC-One Method Supports both Thermodynamic and Kinetic SARs as Exemplified on FimH Antagonists. Chemistry (Weinheim an der Bergstrasse, Germany) 24 (49) (2018)
Christoph P Sager, Deniz Eriş, Martin Smieško, Rachel Hevey, Beat Ernst
What contributes to an effective mannose recognition domain? Beilstein journal of organic chemistry 13 (2017)
Christoph P Sager, Brigitte Fiege, Pascal Zihlmann, Raghu Vannam, Said Rabbani, Roman Peter Jakob, Roland C Preston, Adam Zalewski, Timm Maier, Mark W Peczuh, Beat Ernst
The price of flexibility - a case study on septanoses as pyranose mimetics. Chemical science 9 (3) (2017)
Katharina Mayer, Deniz Eris, Oliver Schwardt, Christoph P Sager, Said Rabbani, Simon Kleeb, Beat Ernst
Urinary Tract Infection: Which Conformation of the Bacterial Lectin FimH Is Therapeutically Relevant? Journal of medicinal chemistry 60 (13) (2017)
Thomas Aeschbacher, Mirko Zierke, Martin Smieško, Mayeul Collot, Jean-Maurice Mallet, Beat Ernst, Frédéric Hai-Trieu Allain, Mario Schubert
A Secondary Structural Element in a Wide Range of Fucosylated Glycoepitopes. Chemistry (Weinheim an der Bergstrasse, Germany) 23 (48) (2017)