Alexander Titz (Matthias Gehringer)

Scopus Author ID ResearcherID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 31

Top Venues

Journal of medicinal chemistry

Beilstein journal of organic chemistry

Chemical science

Nature reviews. Chemistry

Helmholtz-Zentrum für Infektionsforschung GmbH

University of Basel (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Helmholtz-Zentrum für Infektionsforschung GmbH

Germany

Group Leader :: Chemical Biology of Carbohydrates

Universität Konstanz Fachbereich Chemie

Germany

Research Fellow Zukunftskolleg :: Chemistry

Education History

University of Basel

Switzerland

PHD :: Pharmacy

Publications

Olga Metelkina, Jelena Konstantinović, Andreas Klein, Roya Shafiei, Mario Fares, Alaa Alhayek, Samir Yahiaoui, Walid A M Elgaher, Jörg Haupenthal, Alexander Titz, Anna Katharina Herta Hirsch
Dual inhibitors of Pseudomonas aeruginosa virulence factors LecA and LasB. Chemical science 15 (33) (2024)
Stefan A Laufer, Alexander Titz, Alexander Titz
Journal of Medicinal Chemistry Collection: Drug Discovery in Germany. Journal of medicinal chemistry (2024)
Stefan A Laufer, Alexander Titz, Alexander Titz
Journal of Medicinal Chemistry Collection: Drug Discovery in Germany. Journal of medicinal chemistry 67 (4) (2024)
Stefan A Laufer, Alexander Titz, Alexander Titz
Journal of Medicinal Chemistry Collection: Drug Discovery in Germany. Journal of medicinal chemistry 67 (4) (2024)
Olga Metelkina, Jelena Konstantinović, Andreas Klein, Roya Shafiei, Mario Fares, Alaa Alhayek, Samir Yahiaoui, Walid A M Elgaher, Jörg Haupenthal, Alexander Titz, Anna Katharina Herta Hirsch
Dual inhibitors of Pseudomonas aeruginosa virulence factors LecA and LasB. Chemical science 15 (33) (2024)
Karolina Wojtczak, Eva Zahorska, Ian J Murphy, Finnja Koppel, Gordon Cooke, Alexander Titz, Joseph P Byrne
Switch-on luminescent sensing of unlabelled bacterial lectin by terbium(III) glycoconjugate systems. Chemical communications (Cambridge, England) (2023)
Steffen Leusmann, Petra Ménová, Elena Shanin, Alexander Titz, Christoph Rademacher
Glycomimetics for the inhibition and modulation of lectins. Chemical Society reviews (2023)
Janina Sponsel, Yubing Guo, Lutfir Hamzam, Alice C Lavanant, Annia Pérez-Riverón, Emma Partiot, Quentin Muller, Julien Rottura, Raphaël Gaudin, Dirk Hauck, Alexander Titz, Vincent Flacher, Winfried Römer, Christopher G Mueller
Pseudomonas aeruginosa LecB suppresses immune responses by inhibiting transendothelial migration. EMBO reports (2023)
Caroline Hoffmann, Matthias Jourdain, Alexander Grandjean, Alexander Titz, Gregor Jung
β-Boronic Acid-Substituted Bodipy Dyes for Fluorescence Anisotropy Analysis of Carbohydrate Binding. Analytical chemistry 94 (16) (2022)
Joscha Meiers, Katharina Rox, Alexander Titz
Lectin-Targeted Prodrugs Activated by Pseudomonas aeruginosa for Self-Destructive Antibiotic Release. Journal of medicinal chemistry 65 (20) (2022)
Patrycja Mała, Eike Siebs, Joscha Meiers, Katharina Rox, Annabelle Varrot, Anne Imberty, Alexander Titz
Discovery of N -β-l-Fucosyl Amides as High-Affinity Ligands for the Pseudomonas aeruginosa Lectin LecB. Journal of medicinal chemistry 65 (20) (2022)
Marina Borisova, Katja Balbuchta, Andrew Lovering, Alexander Titz, Christoph Mayer
NamZ1 and NamZ2 from the Oral Pathogen Tannerella forsythia Are Peptidoglycan Processing Exo-β- N -Acetylmuramidases with Distinct Substrate Specificities. Journal of bacteriology 204 (3) (2022)
Olga Metelkina, Benedikt Huck, Jonathan S O'Connor, Marcus Koch, Andreas Manz, Claus-Michael Lehr, Alexander Titz
Targeting extracellular lectins of Pseudomonas aeruginosa with glycomimetic liposomes. Journal of materials chemistry. B 10 (4) (2022)
Elena Shanina, Sakonwan Kuhaudomlarp, Eike Siebs, Felix F Fuchsberger, Maxime Denis, Priscila da Silva Figueiredo Celestino Gomes, Mads Hartvig Clausen, Peter H Seeberger, Didier Rognan, Alexander Titz, Anne Imberty, Christoph Rademacher
Targeting undruggable carbohydrate recognition sites through focused fragment library design. Communications chemistry 5 (1) (2022)
Elena Shanina, Sakonwan Kuhaudomlarp, Eike Siebs, Felix F Fuchsberger, Maxime Denis, Priscila da Silva Figueiredo Celestino Gomes, Mads Hartvig Clausen, Peter H Seeberger, Didier Rognan, Alexander Titz, Anne Imberty, Christoph Rademacher
Targeting undruggable carbohydrate recognition sites through focused fragment library design. Communications chemistry 5 (1) (2022)
Marcus Miethke, Marco Pieroni, Tilmann Weber, Mark Brönstrup, Peter Hammann, Ludovic Halby, Paola B Arimondo, Philippe Glaser, Bertrand Aigle, Helge B Bode, Rui Moreira, Yanyan Li, Andriy Luzhetskyy, Marnix H Medema, Jean-Luc Pernodet, Marc Stadler, José Rubén Tormo, Olga Genilloud, Andrew W Truman, Kira J Weissman, Eriko Takano, Stefano Sabatini, Evi Stegmann, Heike Brötz-Oesterhelt, Wolfgang Wohlleben, Myriam Seemann, Martin Empting, Anna K H Hirsch, Brigitta Loretz, Claus-Michael Lehr, Alexander Titz, Jennifer Herrmann, Timo Jaeger, Silke Alt, Thomas Hesterkamp, Mathias Winterhalter, Andrea Schiefer, Kenneth M Pfarr, Achim Hoerauf, Heather Graz, Michael Graz, Mika Lindvall, Savithri Ramurthy, Anders Karlén, Maarten van Dongen, Hrvoje Petkovic, Andreas Keller, Frédéric Peyrane, Stefano Donadio, Laurent Fraisse, Laura J V Piddock, Ian H Gilbert, Heinz E Moser, Daniel Krug
Towards the sustainable discovery and development of new antibiotics. Nature reviews. Chemistry 5 (10) (2021)
Eike Siebs, Elena Shanin, Sakonwan Kuhaudomlarp, Priscila da Silva Figueiredo Celestino Gomes, Cloé Fortin, Peter H Seeberger, Didier Rognan, Christoph Rademacher, Anne Imberty, Alexander Titz
Targeting the Central Pocket of the Pseudomonas aeruginosa Lectin LecA. Chembiochem : a European journal of chemical biology (2021)
Sakonwan Kuhaudomlarp, Eike Siebs, Elena Shanin, Jérémie Topin, Ines Joachim, Priscila da Silva Figueiredo Celestino Gomes, Annabelle Varrot, Didier Rognan, Christoph Rademacher, Anne Imberty, Alexander Titz
Non-Carbohydrate Glycomimetics as Inhibitors of Calcium(II)-Binding Lectins. Angewandte Chemie (International ed. in English) 60 (15) (2021)
Marcus Miethke, Marco Pieroni, Tilmann Weber, Mark Brönstrup, Peter Hammann, Ludovic Halby, Paola B Arimondo, Philippe Glaser, Bertrand Aigle, Helge B Bode, Rui Moreira, Yanyan Li, Andriy Luzhetskyy, Marnix H Medema, Jean-Luc Pernodet, Marc Stadler, José Rubén Tormo, Olga Genilloud, Andrew W Truman, Kira J Weissman, Eriko Takano, Stefano Sabatini, Evi Stegmann, Heike Brötz-Oesterhelt, Wolfgang Wohlleben, Myriam Seemann, Martin Empting, Anna K H Hirsch, Brigitta Loretz, Claus-Michael Lehr, Alexander Titz, Jennifer Herrmann, Timo Jaeger, Silke Alt, Thomas Hesterkamp, Mathias Winterhalter, Andrea Schiefer, Kenneth M Pfarr, Achim Hoerauf, Heather Graz, Michael Graz, Mika Lindvall, Savithri Ramurthy, Anders Karlén, Maarten van Dongen, Hrvoje Petkovic, Andreas Keller, Frédéric Peyrane, Stefano Donadio, Laurent Fraisse, Laura J V Piddock, Ian H Gilbert, Heinz E Moser, Daniel Krug
Towards the sustainable discovery and development of new antibiotics. Nature reviews. Chemistry 5 (10) (2021)
Robert Wawrzinek, Eike-Christian Wamhoff, Jonathan Lefebre, Mareike Rentzsch, Gunnar Bachem, Gary Domeniconi, Jessica Schulze, Felix F Fuchsberger, Hengxi Zhang, Carlos Modenutti, Lennart Schnirch, Marcelo A Marti, Oliver Schwardt, Maria Bräutigam, Mónica Guberman, Dirk Hauck, Peter H Seeberger, Oliver Seitz, Alexander Titz, Beat Ernst, Christoph Rademacher
A Remote Secondary Binding Pocket Promotes Heteromultivalent Targeting of DC-SIGN. Journal of the American Chemical Society 143 (45) (2021)
Apurva Panjla, Grace Kaul, Sidharth Chopra, Alexander Titz, Sandeep Verma
Short Peptides and Their Mimetics as Potent Antibacterial Agents and Antibiotic Adjuvants. ACS chemical biology (2021)
Marcus Miethke, Marco Pieroni, Tilmann Weber, Mark Brönstrup, Peter Hammann, Ludovic Halby, Paola B Arimondo, Philippe Glaser, Bertrand Aigle, Helge B Bode, Rui Moreira, Yanyan Li, Andriy Luzhetskyy, Marnix H Medema, Jean-Luc Pernodet, Marc Stadler, José Rubén Tormo, Olga Genilloud, Andrew W Truman, Kira J Weissman, Eriko Takano, Stefano Sabatini, Evi Stegmann, Heike Brötz-Oesterhelt, Wolfgang Wohlleben, Myriam Seemann, Martin Empting, Anna K H Hirsch, Brigitta Loretz, Claus-Michael Lehr, Alexander Titz, Jennifer Herrmann, Timo Jaeger, Silke Alt, Thomas Hesterkamp, Mathias Winterhalter, Andrea Schiefer, Kenneth M Pfarr, Achim Hoerauf, Heather Graz, Michael Graz, Mika Lindvall, Savithri Ramurthy, Anders Karlén, Maarten van Dongen, Hrvoje Petkovic, Andreas Keller, Frédéric Peyrane, Stefano Donadio, Laurent Fraisse, Laura J V Piddock, Ian H Gilbert, Heinz E Moser, Daniel Krug
Towards the sustainable discovery and development of new antibiotics. Nature reviews. Chemistry (2021)
Eva Zahorska, Sakonwan Kuhaudomlarp, Saverio Minervini, Sultaan Yousaf, Martin Lepsik, Thorsten Kinsinger, Anna Katharina Herta Hirsch, Anne Imberty, Alexander Titz
A rapid synthesis of low-nanomolar divalent LecA inhibitors in four linear steps from d-galactose pentaacetate. Chemical communications (Cambridge, England) 56 (62) (2021)
Joscha Meiers, Eva Zahorska, Teresa Röhrig, Dirk Hauck, Stefanie Wagner, Alexander Titz
Directing Drugs to Bugs: Antibiotic-Carbohydrate Conjugates Targeting Biofilm-Associated Lectins of Pseudomonas aeruginosa. Journal of medicinal chemistry 63 (20) (2020)
Roman Sommer, Katharina Rox, Stefanie Wagner, Dirk Hauck, Sarah S Henrikus, Shelby Newsad, Tatjana Arnold, Thomas Ryckmans, Mark Brönstrup, Anne Imberty, Annabelle Varrot, Rolf Wolfgang Hartmann, Alexander Titz
Anti-biofilm Agents against Pseudomonas aeruginosa: A Structure-Activity Relationship Study of C-Glycosidic LecB Inhibitors. Journal of medicinal chemistry 62 (20) (2019)
David C B Siebert, Roman Sommer, Domen Pogorevc, Michael Hoffmann, Silke C Wenzel, Daniel Krug, Alexander Titz
Chemical synthesis of tripeptide thioesters for the biotechnological incorporation into the myxobacterial secondary metabolite argyrin via mutasynthesis. Beilstein journal of organic chemistry 15 (2019)
Matthew B Calvert, Varsha R Jumde, Alexander Titz
Pathoblockers or antivirulence drugs as a new option for the treatment of bacterial infections. Beilstein journal of organic chemistry 14 (2018)
Roman Sommer, Stefanie Wagner, Katharina Rox, Annabelle Varrot, Dirk Hauck, Eike-Christian Wamhoff, Janine Schreiber, Thomas Ryckmans, Thomas Brunner, Christoph Rademacher, Rolf Wolfgang Hartmann, Mark Brönstrup, Anne Imberty, Alexander Titz
Glycomimetic, Orally Bioavailable LecB Inhibitors Block Biofilm Formation of Pseudomonas aeruginosa. Journal of the American Chemical Society 140 (7) (2018)
Stefanie Wagner, Dirk Hauck, Michael Hoffmann, Roman Sommer, Ines Joachim, Rolf Müller, Anne Imberty, Annabelle Varrot, Alexander Titz
Covalent Lectin Inhibition and Application in Bacterial Biofilm Imaging. Angewandte Chemie (International ed. in English) 56 (52) (2017)
Matthew B Calvert, Christoph Mayer, Alexander Titz
An efficient synthesis of 1,6-anhydro-N-acetylmuramic acid from N-acetylglucosamine. Beilstein journal of organic chemistry 13 (2017)
Roman Sommer, Stefanie Wagner, Annabelle Varrot, Corwin M Nycholat, Ariane Khaledi, Susanne Häussler, James C Paulson, Anne Imberty, Alexander Titz
The virulence factor LecB varies in clinical isolates: consequences for ligand binding and drug discovery. Chemical science 7 (8) (2016)

Alexander Titz.css-eqlu8i{font-size:small;padding-left:4px;} (Matthias Gehringer)

Publication Activity (10 Years)

Top Topics

Top Venues

Alexander Titz (Matthias Gehringer)