Charles Brenner

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 31

Top Venues

The EMBO journal

Science advances

Molecular cancer therapeutics

Nature metabolism

University of Iowa

Stanford University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Iowa

United States

Professor and Head :: Biochemistry

Dartmouth College Geisel School of Medicine

United States

associate and full professor :: Norris Cotton Cancer Center

Thomas Jefferson University

United States

assistant and associate professor :: Kimmel Cancer Center

Brandeis University

United States

post-doctoral fellow :: Rosenstiel Center

DNAX Research Institute

United States

research assistant :: Molecular Biology

Chiron Corporation

United States

research assistant

Education History

Stanford University

United States

PHD :: Biochemistry & Program in Cancer Biology

Publications

Quanjiang Zhang, Zhonggang Li, Qiuxia Li, Samuel A J Trammell, Mark S Schmidt, Karla Maria Pires, Jinjin Cai, Yuan Zhang, Helena Kenny, Sihem Boudina, Charles Brenner, E Dale Abel
Control of NAD + homeostasis by autophagic flux modulates mitochondrial and cardiac function. The EMBO journal 43 (3) (2024)
Matthew A Murray, Katelyn J Noronha, Yazhe Wang, Anna P Friedman, Sateja Paradkar, Hee Won Suh, Ranjini K Sundaram, Charles Brenner, W Mark Saltzman, Ranjit S Bindra
Exploiting Metabolic Defects in Glioma with Nanoparticle-Encapsulated NAMPT Inhibitors. Molecular cancer therapeutics 23 (8) (2024)
Quanjiang Zhang, Zhonggang Li, Qiuxia Li, Samuel A J Trammell, Mark S Schmidt, Karla Maria Pires, Jinjin Cai, Yuan Zhang, Helena Kenny, Sihem Boudina, Charles Brenner, E Dale Abel
Control of NAD + homeostasis by autophagic flux modulates mitochondrial and cardiac function. The EMBO journal (2024)
Matthew A Murray, Katelyn J Noronha, Yazhe Wang, Anna P Friedman, Sateja Paradkar, Hee Won Suh, Ranjini K Sundaram, Charles Brenner, W Mark Saltzman, Ranjit S Bindra
Exploiting Metabolic Defects in Glioma with Nanoparticle Encapsulated NAMPT Inhibitors. Molecular cancer therapeutics (2024)
Matthew A Murray, Katelyn J Noronha, Yazhe Wang, Anna P Friedman, Sateja Paradkar, Hee Won Suh, Ranjini K Sundaram, Charles Brenner, W Mark Saltzman, Ranjit S Bindra
Exploiting Metabolic Defects in Glioma with Nanoparticle-Encapsulated NAMPT Inhibitors. Molecular cancer therapeutics 23 (8) (2024)
Quanjiang Zhang, Zhonggang Li, Qiuxia Li, Samuel A J Trammell, Mark S Schmidt, Karla Maria Pires, Jinjin Cai, Yuan Zhang, Helena Kenny, Sihem Boudina, Charles Brenner, E Dale Abel
Control of NAD + homeostasis by autophagic flux modulates mitochondrial and cardiac function. The EMBO journal 43 (3) (2024)
Matthew A Murray, Katelyn J Noronha, Yazhe Wang, Anna P Friedman, Sateja Paradkar, Hee Won Suh, Ranjini K Sundaram, Charles Brenner, W Mark Saltzman, Ranjit S Bindra
Exploiting Metabolic Defects in Glioma with Nanoparticle-Encapsulated NAMPT Inhibitors. Molecular cancer therapeutics 23 (8) (2024)
Quanjiang Zhang, Zhonggang Li, Qiuxia Li, Samuel A J Trammell, Mark S Schmidt, Karla Maria Pires, Jinjin Cai, Yuan Zhang, Helena Kenny, Sihem Boudina, Charles Brenner, E Dale Abel
Control of NAD + homeostasis by autophagic flux modulates mitochondrial and cardiac function. The EMBO journal 43 (3) (2024)
Matthew A Murray, Katelyn J Noronha, Yazhe Wang, Anna P Friedman, Sateja Paradkar, Hee Won Suh, Ranjini K Sundaram, Charles Brenner, W Mark Saltzman, Ranjit S Bindra
Exploiting Metabolic Defects in Glioma with Nanoparticle-Encapsulated NAMPT Inhibitors. Molecular cancer therapeutics 23 (8) (2024)
Quanjiang Zhang, Zhonggang Li, Qiuxia Li, Samuel A J Trammell, Mark S Schmidt, Karla Maria Pires, Jinjin Cai, Yuan Zhang, Helena Kenny, Sihem Boudina, Charles Brenner, E Dale Abel
Control of NAD + homeostasis by autophagic flux modulates mitochondrial and cardiac function. The EMBO journal 43 (3) (2024)
Helena A K Lapatto, Minna Kuusela, Aino Heikkinen, Maheswany Muniandy, Birgitta W van der Kolk, Swetha Gopalakrishnan, Noora Pöllänen, Martin Sandvik, Mark S Schmidt, Sini Heinonen, Sina Saari, Juho Kuula, Antti Hakkarainen, Janne Tampio, Tuure Saarinen, Marja-Riitta Taskinen, Nina Lundbom, Per-Henrik Groop, Marja Tiirola, Pekka Katajisto, Marko Lehtonen, Charles Brenner, Jaakko A Kaprio, Satu Pekkala, Miina Ollikainen, Kirsi H Pietiläinen, Eija Pirinen
Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study. Science advances 9 (2) (2023)
Helena A K Lapatto, Minna Kuusela, Aino Heikkinen, Maheswany Muniandy, Birgitta W van der Kolk, Swetha Gopalakrishnan, Noora Pöllänen, Martin Sandvik, Mark S Schmidt, Sini Heinonen, Sina Saari, Juho Kuula, Antti Hakkarainen, Janne Tampio, Tuure Saarinen, Marja-Riitta Taskinen, Nina Lundbom, Per-Henrik Groop, Marja Tiirola, Pekka Katajisto, Marko Lehtonen, Charles Brenner, Jaakko A Kaprio, Satu Pekkala, Miina Ollikainen, Kirsi H Pietiläinen, Eija Pirinen
Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study. Science advances 9 (2) (2023)
Helena A K Lapatto, Minna Kuusela, Aino Heikkinen, Maheswany Muniandy, Birgitta W van der Kolk, Swetha Gopalakrishnan, Noora Pöllänen, Martin Sandvik, Mark S Schmidt, Sini Heinonen, Sina Saari, Juho Kuula, Antti Hakkarainen, Janne Tampio, Tuure Saarinen, Marja-Riitta Taskinen, Nina Lundbom, Per-Henrik Groop, Marja Tiirola, Pekka Katajisto, Marko Lehtonen, Charles Brenner, Jaakko A Kaprio, Satu Pekkala, Miina Ollikainen, Kirsi H Pietiläinen, Eija Pirinen
Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study. Science advances 9 (2) (2023)
Shu Zhang, Na Xie, Yongzhen Liu, Chao Qin, Ali Can Savas, Ting-Yu Wang, Shutong Li, Youliang Rao, Alexandra Shambayate, Tsui-Fen Chou, Charles Brenner, Canhua Huang, Pinghui Feng
The Interferon-inducible NAMPT acts as a protein phosphoribosylase to restrict viral infection. bioRxiv : the preprint server for biology (2023)
Helena A K Lapatto, Minna Kuusela, Aino Heikkinen, Maheswany Muniandy, Birgitta W van der Kolk, Swetha Gopalakrishnan, Noora Pöllänen, Martin Sandvik, Mark S Schmidt, Sini Heinonen, Sina Saari, Juho Kuula, Antti Hakkarainen, Janne Tampio, Tuure Saarinen, Marja-Riitta Taskinen, Nina Lundbom, Per-Henrik Groop, Marja Tiirola, Pekka Katajisto, Marko Lehtonen, Charles Brenner, Jaakko A Kaprio, Satu Pekkala, Miina Ollikainen, Kirsi H Pietiläinen, Eija Pirinen
Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study. Science advances 9 (2) (2023)
Helena A K Lapatto, Minna Kuusela, Aino Heikkinen, Maheswany Muniandy, Birgitta W van der Kolk, Swetha Gopalakrishnan, Noora Pöllänen, Martin Sandvik, Mark S Schmidt, Sini Heinonen, Sina Saari, Juho Kuula, Antti Hakkarainen, Janne Tampio, Tuure Saarinen, Marja-Riitta Taskinen, Nina Lundbom, Per-Henrik Groop, Marja Tiirola, Pekka Katajisto, Marko Lehtonen, Charles Brenner, Jaakko A Kaprio, Satu Pekkala, Miina Ollikainen, Kirsi H Pietiläinen, Eija Pirinen
Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study. Science advances 9 (2) (2023)
Charles Brenner
Viral infection as an NAD + battlefield. Nature metabolism 4 (1) (2022)
Charles Brenner
Comment on "Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women". Science (New York, N.Y.) 373 (6554) (2021)
Maria Gerasimenko, Stanislav M Cherepanov, Kazumi Furuhara, Olga Lopatina, Alla B Salmina, Anna A Shabalova, Chiharu Tsuji, Shigeru Yokoyama, Katsuhiko Ishihara, Charles Brenner, Haruhiro Higashida
Nicotinamide riboside supplementation corrects deficits in oxytocin, sociability and anxiety of CD157 mutants in a mouse model of autism spectrum disorder. Scientific reports 10 (1) (2020)
Anthony J Covarrubias, Abhijit Kale, Rosalba Perrone, José Alberto López-Domínguez, Angela Oliveira Pisco, Herbert G Kasler, Mark S Schmidt, Indra Heckenbach, Ryan Kwok, Christopher D Wiley, Hoi-Shan Wong, Eddy Gibbs, Shankar S Iyer, Nathan Basisty, Qiuxia Wu, Ik-Jung Kim, Elena Silva, Kaitlyn Vitangcol, Kyong-Oh Shin, Yong-Moon Lee, Rebeccah Riley, Issam Ben-Sahra, Melanie Ott, Birgit Schilling, Morten Scheibye-Knudsen, Katsuhiko Ishihara, Stephen R Quake, John C Newman, Charles Brenner, Judith Campisi, Eric Verdin
Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages. Nature metabolism 2 (11) (2020)
Anthony J Covarrubias, Abhijit Kale, Rosalba Perrone, José Alberto López-Domínguez, Angela Oliveira Pisco, Herbert G Kasler, Mark S Schmidt, Indra Heckenbach, Ryan Kwok, Christopher D Wiley, Hoi-Shan Wong, Eddy Gibbs, Shankar S Iyer, Nathan Basisty, Qiuxia Wu, Ik-Jung Kim, Elena Silva, Kaitlyn Vitangcol, Kyong-Oh Shin, Yong-Moon Lee, Rebeccah Riley, Issam Ben-Sahra, Melanie Ott, Birgit Schilling, Morten Scheibye-Knudsen, Katsuhiko Ishihara, Stephen R Quake, John C Newman, Charles Brenner, Judith Campisi, Eric Verdin
Author Correction: Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages. Nature metabolism (2020)
Rahul Ghugari, Sarah Tsao, Mark S Schmidt, Éric Bonneil, Charles Brenner, Alain Verreault
Mechanisms to reduce the cytotoxicity of pharmacological nicotinamide concentrations in the pathogenic fungus Candida albicans. The FEBS journal 288 (11) (2020)
Richard Parker, Mark S Schmidt, Owen Cain, Bridget Gunson, Charles Brenner
Nicotinamide Adenine Dinucleotide Metabolome Is Functionally Depressed in Patients Undergoing Liver Transplantation for Alcohol-Related Liver Disease. Hepatology communications 4 (8) (2020)
Charles Brenner
Why Is Mom Stressed: Homeorhesis as the Potential Problem and Nicotinamide Riboside as the Potential Solution. Journal of experimental neuroscience 13 (2019)
Nathan R Fons, Ranjini K Sundaram, Gregory A Breuer, Sen Peng, Ryan L McLean, Aravind N Kalathil, Mark S Schmidt, Diana M Carvalho, Alan Mackay, Chris Jones, Angel Montero Carcaboso, Javad Nazarian, Michael E Berens, Charles Brenner, Ranjit S Bindra
PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma. Nature communications 10 (1) (2019)
Mark S Schmidt, Charles Brenner
Absence of evidence that Slc12a8 encodes a nicotinamide mononucleotide transporter. Nature metabolism 1 (7) (2019)
Dietrich Conze, Charles Brenner, Claire L Kruger
Safety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults. Scientific reports 9 (1) (2019)
Hui-Wen Liu, Chadwick B Smith, Mark S Schmidt, Xiaolu A Cambronne, Michael S Cohen, Marie E Migaud, Charles Brenner, Richard H Goodman
Pharmacological bypass of NAD+ salvage pathway protects neurons from chemotherapy-induced degeneration. Proceedings of the National Academy of Sciences of the United States of America 115 (42) (2018)
Samuel Aj Trammell, Liping Yu, Philip Redpath, Marie E Migaud, Charles Brenner
Nicotinamide Riboside Is a Major NAD+ Precursor Vitamin in Cow Milk. The Journal of nutrition 146 (5) (2016)
Joanna Ratajczak, Magali Joffraud, Samuel A J Trammell, Rosa Ras, Núria Canela, Marie Boutant, Sameer S Kulkarni, Marcelo Rodrigues, Philip Redpath, Marie E Migaud, Johan Auwerx, Óscar Yanes, Charles Brenner, Carles Canto
NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells. Nature communications 7 (2016)
Samuel A J Trammell, Mark S Schmidt, Benjamin J Weidemann, Philip Redpath, Frank Jaksch, Ryan W Dellinger, Zhonggang Li, E Dale Abel, Marie E Migaud, Charles Brenner
Nicotinamide riboside is uniquely and orally bioavailable in mice and humans. Nature communications 7 (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Charles Brenner