Chia-Ju Hsieh

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 20

Top Topics

Oxidative Stress

Top Venues

International journal of molecular sciences

Journal of medicinal chemistry

Molecules (Basel, Switzerland)

Chemical science

This page only lists publications with an associated author ORCID identifier.

Publications

Evan Gallagher, Catherine Hou, Yi Zhu, Chia-Ju Hsieh, Hsiaoju Lee, Shihong Li, Kuiying Xu, Patrick Henderson, Rea Chroneos, Malkah Sheldon, Shaipreeah Riley, Kelvin C Luk, Robert H Mach, Meagan J McManus
Positron Emission Tomography with [ 18 F]ROStrace Reveals Progressive Elevations in Oxidative Stress in a Mouse Model of Alpha-Synucleinopathy. International journal of molecular sciences 25 (9) (2024)
Evan Gallagher, Catherine Hou, Yi Zhu, Chia-Ju Hsieh, Hsiaoju Lee, Shihong Li, Kuiying Xu, Patrick Henderson, Rea Chroneos, Malkah Sheldon, Shaipreeah Riley, Kelvin C Luk, Robert H Mach, Meagan J McManus
Positron Emission Tomography with [ 18 F]ROStrace Reveals Progressive Elevations in Oxidative Stress in a Mouse Model of Alpha-Synucleinopathy. International journal of molecular sciences 25 (9) (2024)
Evan Gallagher, Catherine Hou, Yi Zhu, Chia-Ju Hsieh, Hsiaoju Lee, Shihong Li, Kuiying Xu, Patrick Henderson, Rea Chroneos, Malkah Sheldon, Shaipreeah Riley, Kelvin C Luk, Robert H Mach, Meagan J McManus
Positron Emission Tomography with [ 18 F]ROStrace Reveals Progressive Elevations in Oxidative Stress in a Mouse Model of Alpha-Synucleinopathy. International journal of molecular sciences 25 (9) (2024)
Ho Young Kim, Wai Kit Chia, Chia-Ju Hsieh, Dinahlee Saturnino Guarino, Thomas J A Graham, Zsofia Lengyel-Zhand, Mark Schneider, Cosette Tomita, Marshall G Lougee, Hee Jong Kim, Vinayak V Pagar, Hsiaoju Lee, Catherine Hou, Benjamin A Garcia, E James Petersson, Jennifer O'Shea, Paul T Kotzbauer, Chester A Mathis, Virginia M-Y Lee, Kelvin C Luk, Robert H Mach
A Novel Brain PET Radiotracer for Imaging Alpha Synuclein Fibrils in Multiple System Atrophy. Journal of medicinal chemistry (2023)
Chia-Ju Hsieh, Sam Giannakoulias, E James Petersson, Robert H Mach
Computational Chemistry for the Identification of Lead Compounds for Radiotracer Development. Pharmaceuticals (Basel, Switzerland) 16 (2) (2023)
Gui-Long Tian, Chia-Ju Hsieh, Michelle Taylor, Ji Youn Lee, Robert R Luedtke, Robert H Mach
Design and Synthesis of D 3 R Bitopic Ligands with Flexible Secondary Binding Fragments: Radioligand Binding and Computational Chemistry Studies. Molecules (Basel, Switzerland) 29 (1) (2023)
Gui-Long Tian, Chia-Ju Hsieh, Michelle Taylor, Ji Youn Lee, Robert R Luedtke, Robert H Mach
Design and Synthesis of D 3 R Bitopic Ligands with Flexible Secondary Binding Fragments: Radioligand Binding and Computational Chemistry Studies. Molecules (Basel, Switzerland) 29 (1) (2023)
Gui-Long Tian, Chia-Ju Hsieh, Michelle Taylor, Ji Youn Lee, Robert R Luedtke, Robert H Mach
Design and Synthesis of D 3 R Bitopic Ligands with Flexible Secondary Binding Fragments: Radioligand Binding and Computational Chemistry Studies. Molecules (Basel, Switzerland) 29 (1) (2023)
Ho Young Kim, Ji Youn Lee, Chia-Ju Hsieh, Aladdin Riad, Nicholas J Izzo, Susan M Catalano, Thomas J A Graham, Robert H Mach
Screening of σ 2 Receptor Ligands and In Vivo Evaluation of 11 C-Labeled 6,7-Dimethoxy-2-[4-(4-methoxyphenyl)butan-2-yl]-1,2,3,4-tetrahydroisoquinoline for Potential Use as a σ 2 Receptor Brain PET Tracer. Journal of medicinal chemistry 65 (8) (2022)
Ho Young Kim, Ji Youn Lee, Chia-Ju Hsieh, Michelle Taylor, Robert R Luedtke, Robert H Mach
Design and Synthesis of Conformationally Flexible Scaffold as Bitopic Ligands for Potent D 3 -Selective Antagonists. International journal of molecular sciences 24 (1) (2022)
Kuiying Xu, Chia-Ju Hsieh, Ji Youn Lee, Aladdin Riad, Nicholas J Izzo, Gary Look, Susan Catalano, Robert H Mach
Exploration of Diazaspiro Cores as Piperazine Bioisosteres in the Development of σ2 Receptor Ligands. International journal of molecular sciences 23 (15) (2022)
Austin Ryan Pantel, Sarah B Gitto, Mehran Makvandi, Hyoung Kim, Sergey Medvedv, Joanna K Weeks, Drew A Torigian, Chia-Ju Hsieh, Benjamin Ferman, Nawar A Latif, Janos L Tanyi, Lainie P Martin, Shannon M Lanzo, Fang Liu, Quy Cao, Gordon B Mills, Robert K Doot, David A Mankoff, Robert H Mach, Lilie L Lin, Fiona Simpkins
[18F]FluorThanatrace ([18F]FTT) PET Imaging of PARP-inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a pilot study. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Ho Young Kim, Ji Youn Lee, Chia-Ju Hsieh, Michelle Taylor, Robert R Luedtke, Robert H Mach
Design and Synthesis of Conformationally Flexible Scaffold as Bitopic Ligands for Potent D 3 -Selective Antagonists. International journal of molecular sciences 24 (1) (2022)
Ho Young Kim, Ji Youn Lee, Chia-Ju Hsieh, Michelle Taylor, Robert R Luedtke, Robert H Mach
Design and Synthesis of Conformationally Flexible Scaffold as Bitopic Ligands for Potent D 3 -Selective Antagonists. International journal of molecular sciences 24 (1) (2022)
Chia-Ju Hsieh, Aladdin Riad, Ji Youn Lee, Kristoffer Sahlholm, Kuiying Xu, Robert R Luedtke, Robert H Mach
Interaction of Ligands for PET with the Dopamine D3 Receptor: In Silico and In Vitro Methods. Biomolecules 11 (4) (2021)
John J Ferrie, Zsofia Lengyel-Zhand, Bieneke Janssen, Marshall G Lougee, Sam G Giannakoulias, Chia-Ju Hsieh, Vinayak Vishnu Pagar, Chi-Chang Weng, Hong Xu, Thomas J A Graham, Virginia M-Y Lee, Robert H Mach, E James Petersson
Identification of a nanomolar affinity α-synuclein fibril imaging probe by ultra-high throughput in silico screening. Chemical science 11 (47) (2020)
Aladdin Riad, Sarah B Gitto, Hwan Lee, Harrison D Winters, Paul M Martorano, Chia-Ju Hsieh, Kuiying Xu, Dalia K Omran, Daniel J Powell, Robert H Mach, Mehran Makvandi
PARP Theranostic Auger Emitters Are Cytotoxic in BRCA Mutant Ovarian Cancer and Viable Tumors from Ovarian Cancer Patients Enable Ex-Vivo Screening of Tumor Response. Molecules (Basel, Switzerland) 25 (24) (2020)
Sean W Reilly, Aladdin A Riad, Chia-Ju Hsieh, Kristoffer Sahlholm, Daniel A Jacome, Suzy Griffin, Michelle Taylor, Chi-Chang Weng, Kuiying Xu, Nathan Kirschner, Robert R Luedtke, Christopher Parry, Shipra Malhotra, John Karanicolas, Robert H Mach
Leveraging a Low-Affinity Diazaspiro Orthosteric Fragment to Reduce Dopamine D3 Receptor (D3R) Ligand Promiscuity across Highly Conserved Aminergic G-Protein-Coupled Receptors (GPCRs). Journal of medicinal chemistry 62 (10) (2019)
Chia-Ju Hsieh, John J Ferrie, Kuiying Xu, Iljung Lee, Thomas J A Graham, Zhude Tu, Jennifer Yu, Dhruva Dhavale, Paul Kotzbauer, E James Petersson, Robert H Mach
Alpha Synuclein Fibrils Contain Multiple Binding Sites for Small Molecules. ACS chemical neuroscience 9 (11) (2018)
Sean W Reilly, Laura N Puentes, Khadija Wilson, Chia-Ju Hsieh, Chi-Chang Weng, Mehran Makvandi, Robert H Mach
Examination of Diazaspiro Cores as Piperazine Bioisosteres in the Olaparib Framework Shows Reduced DNA Damage and Cytotoxicity. Journal of medicinal chemistry 61 (12) (2018)