Fiona Simpkins

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 10

Top Topics

Endometrial Cancer

Top Venues

Research square

Clinical cancer research : an official journal of the American Association for Cancer Research

Science signaling

This page only lists publications with an associated author ORCID identifier.

Publications

Haineng Xu, Erin George, David Gallo, Sergey Medvedev, Xiaolei Wang, Rosie Kryczka, Marc L Hyer, Jimmy Fourtounis, Rino Stocco, Elia Aguado-Fraile, Adam Petrone, Shou Yun Yin, Ariya Shiwram, Matthew Anderson, Hyoung Kim, Fang Liu, C Gary Marshall, Fiona Simpkins
Targeting CCNE1 amplified ovarian and endometrial cancers by combined inhibition of PKMYT1 and ATR. Research square (2024)
Fiona Simpkins, Haineng Xu, Erin Geroge, David Gallo, Sergey Medvedev, Xiaolei Wang, Rosie Kryczka, Marc Hyer, Jimmy Fourtounis, Rino Stocco, Elia Aguado-Fraile, Adam Petrone, Shou Yun Yin, Ariya Shiwram, Matthew Anderson, Hyoung Kim, Fang Liu, Gary Marshall
Targeting CCNE1 amplified ovarian and endometrial cancers by combined inhibition of PKMYT1 and ATR. Research square (2024)
Stephanie L Wethington, Payal Deepak Shah, Lainie P Martin, Janos L Tanyi, Nawar A Latif, Mark A Morgan, Drew A Torigian, Diego Rodriguez, Simon A Smith, Emma Dean, Susan M Domchek, Ronny Drapkin, Ie-Ming Shih, Eric J Brown, Wei-Ting Hwang, Deborah K Armstrong, Stephanie Gaillard, Robert Giuntoli, Fiona Simpkins
Combination ATR (ceralasertib) and PARP (olaparib) Inhibitor (CAPRI) trial in acquired PARP-inhibitor-resistant homologous recombination deficient ovarian cancer. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Todd M Bauer, Kathleen M Moore, Janet S Rader, Fiona Simpkins, Alain C Mita, J Thaddeus Beck, Lowell Hart, Quincy Chu, Amit Oza, Sarah A Cook, Esteban Rodrigo Imedio, Sanjeev Kumar, Ganesh M Mugundu, Suzanne Jenkins, Juliann Chmielecki, Suzanne F Jones, David R Spigel, Siqing Fu
A Phase Ib Study Assessing the Safety, Tolerability, and Efficacy of the First-in-Class Wee1 Inhibitor Adavosertib (AZD1775) as Monotherapy in Patients with Advanced Solid Tumors. Targeted oncology (2023)
Sarah B Gitto, Margaret E Whicker, Gareth Davies, Sushil Kumar, Krista Kinneer, Haineng Xu, Arthur Lewis, Srinivas Mamidi, Sergey Medvedv, Hyoung Kim, Judith Anderton, E Jessica Tang, Benjamin Ferman, Steven Coats, Robert W Wilkinson, Eric J Brown, Daniel J Powell, Fiona Simpkins
A B7-H4 targeting antibody-drug conjugate shows anti-tumor activity in PARPi and platinum resistant cancers with B7-H4 expression. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Fiona Simpkins, Yasuto Kinose, Haineng Xu, Hyoung Kim, Sushil Kumar, Xiaoyin Shan, Erin Geroge, Xiaolei Wang, Sergey Medvedev, Benjamin Ferman, Sarah Gitto, Margaret Whicker, Kurt D Andrea, Bradley Wubbenhorst, Dorothy Hallberg, Lenka Oplustil O'Connor, Lauren Schwartz, Wei-Ting Hwang, Katherine L Nathanson, Gordon B Mills, Victor E Velculescu, Tian-Li Wang, Eric Brown, Ronny Drapkin
Dual blockade of BRD4 and ATR/WEE1 pathways exploits ARID1A loss in clear cell ovarian cancer. Research square (2023)
Austin Ryan Pantel, Sarah B Gitto, Mehran Makvandi, Hyoung Kim, Sergey Medvedv, Joanna K Weeks, Drew A Torigian, Chia-Ju Hsieh, Benjamin Ferman, Nawar A Latif, Janos L Tanyi, Lainie P Martin, Shannon M Lanzo, Fang Liu, Quy Cao, Gordon B Mills, Robert K Doot, David A Mankoff, Robert H Mach, Lilie L Lin, Fiona Simpkins
[18F]FluorThanatrace ([18F]FTT) PET Imaging of PARP-inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a pilot study. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Arlene E Garcia-Soto, Nathalie D McKenzie, Margaret E Whicker, Joseph M Pearson, Edward A Jimenez, Lorraine Portelance, Jennifer J Hu, Joseph A Lucci, Rehman Qureshi, Andrew V Kossenkov, Lauren Schwartz, Gordon B Mills, Amit Maity, Lilie L Lin, Fiona Simpkins
Phase 1 trial of nelfinavir added to standard cisplatin chemotherapy with concurrent pelvic radiation for locally advanced cervical cancer. Cancer 127 (13) (2021)
Sara H Small, E Jessica Tang, Ryan L Ragland, Yaroslava Ruzankina, David W Schoppy, Rahul Shubhra Mandal, M Rebecca Glineburg, Zgjim Ustelenca, Daniel J Powell, Fiona Simpkins, F Bradley Johnson, Eric J Brown
Induction of IL19 expression through JNK and cGAS-STING modulates DNA damage-induced cytokine production. Science signaling 14 (714) (2021)
Hyoung Kim, Haineng Xu, Erin George, Dorothy Hallberg, Sushil Kumar, Veena Jagannathan, Sergey Medvedev, Yasuto Kinose, Kyle Devins, Priyanka Verma, Kevin Ly, Yifan Wang, Roger A Greenberg, Lauren Schwartz, Neil Johnson, Robert B Scharpf, Gordon B Mills, Rugang Zhang, Victor E Velculescu, Eric J Brown, Fiona Simpkins
Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models. Nature communications 11 (1) (2020)