Christine Helsen

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 11

Top Venues

Protein science : a publication of the Protein Society

Molecular cancer research : MCR

Cellular and molecular life sciences : CMLS

Scientific reports

KU Leuven

KU Leuven (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

KU Leuven

Belgium

Postdoctoral researcher :: Cellular and Molecular Medicine

Education History

KU Leuven

Belgium

PHD :: Biomedical Sciences

KU Leuven

Belgium

MSC :: Pharmaceutical Sciences

Publications

Roy Eerlings, Purvi Gupta, Xiao Yin Lee, Tien Nguyen, Sarah El Kharraz, Florian Handle, Elien Smeets, Lisa Moris, Wout Devlies, Bram Vandewinkel, Irina Thiry, Duy Tien Ta, Anton Gorkovskiy, Karin Voordeckers, Els Henckaerts, Vitor B Pinheiro, Frank Claessens, Kevin J Verstrepen, Arnout R D Voet, Christine Helsen
Rational evolution for altering the ligand preference of estrogen receptor alpha. Protein science : a publication of the Protein Society 33 (4) (2024)
Roy Eerlings, Purvi Gupta, Xiao Yin Lee, Tien Nguyen, Sarah El Kharraz, Florian Handle, Elien Smeets, Lisa Moris, Wout Devlies, Bram Vandewinkel, Irina Thiry, Duy Tien Ta, Anton Gorkovskiy, Karin Voordeckers, Els Henckaerts, Vitor B Pinheiro, Frank Claessens, Kevin J Verstrepen, Arnout R D Voet, Christine Helsen
Rational evolution for altering the ligand preference of estrogen receptor alpha. Protein science : a publication of the Protein Society 33 (4) (2024)
Christine Helsen, Maria Santa Rocca, Tien T Nguyen, Roy Eerlings, Xiao Yin Lee, Sofie De Block, Cinzia Vinanzi, Francesco Di Millo, Vito Giagulli, Arnout R D Voet, Alberto Ferlin, Frank Claessens
Study of novel androgen receptor V770 variant in androgen insensitivity syndrome patients reveals the transitional state of the androgen receptor ligand binding domain homodimer. Protein science : a publication of the Protein Society (2023)
Christine Helsen, Maria Santa Rocca, Tien T Nguyen, Roy Eerlings, Xiao Yin Lee, Sofie De Block, Cinzia Vinanzi, Francesco Di Millo, Vito Giagulli, Arnout R D Voet, Alberto Ferlin, Frank Claessens
Study of novel androgen receptor V770 variant in androgen insensitivity syndrome patients reveals the transitional state of the androgen receptor ligand binding domain homodimer. Protein science : a publication of the Protein Society (2023)
Christine Helsen, Tien Nguyen Truong, Xiao Yin Lee, Roy Eerlings, Nikolaos N Louros, Joost Schymkowitz, Frederic Rousseau, Frank Claessens, Arnout R D Voet
Exploiting Ligand-binding Domain Dimerization for Development of Novel Androgen Receptor Inhibitors. Molecular cancer therapeutics 21 (12) (2022)
Christine Helsen, Tien Nguyen, Thomas Vercruysse, Staf Wouters, Dirk Daelemans, Arnout Voet, Frank Claessens
The T850D Phosphomimetic Mutation in the Androgen Receptor Ligand Binding Domain Enhances Recruitment at Activation Function 2. International journal of molecular sciences 23 (3) (2022)
Thomas Van den Broeck, Lisa Moris, Thomas Gevaert, Elai Davicioni, Bram Boeckx, Diether Lambrechts, Christine Helsen, Florian Handle, Bart Ghesquiere, Stefaan Soenen, Elien Smeets, Roy Eerlings, Sarah El Kharraz, Wout Devlies, R Jeffrey Karnes, Tamara Lotan, Hendrik Van Poppel, Steven Joniau, Frank Claessens
Antizyme Inhibitor 1 Regulates Matrikine Expression and Enhances the Metastatic Potential of Aggressive Primary Prostate Cancer. Molecular cancer research : MCR 20 (4) (2022)
Sarah El Kharraz, Vanessa Dubois, Martin E van Royen, Adriaan B Houtsmuller, Ekatarina Pavlova, Nina Atanassova, Nguyen Thanh Tien, Arnout R D Voet, Roy Eerlings, Florian Handle, Stefan Prekovic, Elien Smeets, Lisa Moris, Wout Devlies, Claes Ohlsson, Matti Poutanen, Kevin J Verstrepen, Geert Carmeliet, Kaisa-Mari Launonen, Laura Helminen, Jorma J Palvimo, Claude Libert, Dirk Vanderschueren, Christine Helsen, Frank Claessens
The androgen receptor depends on ligand-binding domain dimerization for transcriptional activation. EMBO reports 22 (12) (2021)
Florian Handle, Stefan Prekovic, Christine Helsen, Thomas Van den Broeck, Elien Smeets, Lisa Moris, Roy Eerlings, Sarah El Kharraz, Alfonso Urbanucci, Ian G Mills, Steven Joniau, Gerhardt Attard, Frank Claessens
Drivers of AR indifferent anti-androgen resistance in prostate cancer cells. Scientific reports 9 (1) (2019)
Marta Nadal, Stefan Prekovic, Nerea Gallastegui, Christine Helsen, Montserrat Abella, Karolina Zielinska, Marina Gay, Marta Vilaseca, Marta Taulès, Adriaan B Houtsmuller, Martin E van Royen, Frank Claessens, Pablo Fuentes-Prior, Eva Estébanez-Perpiñá
Structure of the homodimeric androgen receptor ligand-binding domain. Nature communications 8 (2017)
Frank Claessens, Steven Joniau, Christine Helsen
Comparing the rules of engagement of androgen and glucocorticoid receptors. Cellular and molecular life sciences : CMLS 74 (12) (2017)

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Publication Activity (10 Years)

Top Topics

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Christine Helsen