Frank Claessens (F Claessens)

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 21

Top Venues

Scientific reports

Endocrinology

Nature reviews. Urology

Molecular cancer therapeutics

KU Leuven

KU Leuven (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

KU Leuven

Belgium

P.I. Molecular Endocrinology Laboratory :: Cellular and Molecular Medicine

Education History

KU Leuven Sep 15 1984 - Dec 13 1989

Belgium

PHD

KU Leuven Oct 01 1979 - Jun 30 1983

Belgium

MSC :: Biology

Publications

Vera Sommers, Max Gentenaar, Karel David, Nick Narinx, Vanessa Dubois, Jan Kroon, Frank Claessens, Onno C Meijer
Androgens suppress corticosteroid binding globulin in male mice, affecting the endocrine stress response. Endocrinology (2024)
Justine Habault, Jeffrey A Schneider, Susan Ha, Rachel Ruoff, Luiza D Doro Pereira, Joseph Puccini, Michela Ranieri, Ruveyda Ayasun, Jiehui Deng, Amanda C Kasper, Dafna Bar-Sagi, Kwok-Kin Wong, Amina Zoubeidi, Frank Claessens, David R Wise, Susan K Logan, Kent Kirshenbaum, Michael J Garabedian
A multivalent peptoid conjugate modulates androgen receptor transcriptional activity to inhibit therapy-resistant prostate cancer. Molecular cancer therapeutics (2023)
Christine Helsen, Tien Nguyen Truong, Xiao Yin Lee, Roy Eerlings, Nikolaos N Louros, Joost Schymkowitz, Frederic Rousseau, Frank Claessens, Arnout R D Voet
Exploiting Ligand-binding Domain Dimerization for Development of Novel Androgen Receptor Inhibitors. Molecular cancer therapeutics 21 (12) (2022)
Sarah El Kharraz, Vanessa Dubois, Kaisa-Mari Launonen, Laura Helminen, Jorma J Palvimo, Claude Libert, Elien Smeets, Lisa Moris, Roy Eerlings, Dirk Vanderschueren, Christine Helsen, Frank Claessens
N/C Interactions Are Dispensable for Normal In Vivo Functioning of the Androgen Receptor in Male Mice. Endocrinology 163 (9) (2022)
Karel David, Nick Narinx, Leen Antonio, Pieter Evenepoel, Frank Claessens, Brigitte Decallonne, Dirk Vanderschueren
Bone health in ageing men. Reviews in endocrine & metabolic disorders (2022)
Nick Narinx, Karel David, Joeri Walravens, Pieter Vermeersch, Frank Claessens, Tom Fiers, Bruno Lapauw, Leen Antonio, Dirk Vanderschueren
Role of sex hormone-binding globulin in the free hormone hypothesis and the relevance of free testosterone in androgen physiology. Cellular and molecular life sciences : CMLS 79 (11) (2022)
Elien Smeets, Shengyun Huang, Xiao Yin Lee, Erika Van Nieuwenhove, Christine Helsen, Florian Handle, Lisa Moris, Sarah El Kharraz, Roy Eerlings, Wout Devlies, Mathijs Willemsen, Leoni Bücken, Teresa Prezzemolo, Stephanie Humblet-Baron, Arnout Voet, Anne Rochtus, Ann Van Schepdael, Francis de Zegher, Frank Claessens
A disease-associated missense mutation in CYP4F3 affects the metabolism of leukotriene B4 via disruption of electron transfer. Journal of cachexia, sarcopenia and muscle 13 (4) (2022)
Thomas Van den Broeck, Lisa Moris, Thomas Gevaert, Elai Davicioni, Bram Boeckx, Diether Lambrechts, Christine Helsen, Florian Handle, Bart Ghesquiere, Stefaan Soenen, Elien Smeets, Roy Eerlings, Sarah El Kharraz, Wout Devlies, R Jeffrey Karnes, Tamara Lotan, Hendrik Van Poppel, Steven Joniau, Frank Claessens
Antizyme Inhibitor 1 Regulates Matrikine Expression and Enhances the Metastatic Potential of Aggressive Primary Prostate Cancer. Molecular cancer research : MCR 20 (4) (2022)
Wout Devlies, Frank Claessens
Tracking prostate cancer development at the single-cell level. Nature reviews. Urology 17 (10) (2022)
Sinja Taavitsainen, Nikolai Engedal, S Cao, Florian Handle, A Erickson, Stefan Prekovic, D Wetterskog, Teemu Tolonen, Elisa M Vuorinen, A Kiviaho, R Nätkin, T Häkkinen, W Devlies, S Henttinen, R Kaarijärvi, Mari Lahnalampi, Heidi Kaljunen, K Nowakowska, H Syvälä, M Bläuer, P Cremaschi, Frank Claessens, T Visakorpi, T L J Tammela, T Murtola, Kirsi J Granberg, Alastair D Lamb, K Ketola, I G Mills, Gerhardt Attard, Wenyi Wang, Matti Nykter, Alfonso Urbanucci
Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse. Nature communications 12 (1) (2021)
Sarah El Kharraz, Vanessa Dubois, Martin E van Royen, Adriaan B Houtsmuller, Ekatarina Pavlova, Nina Atanassova, Nguyen Thanh Tien, Arnout R D Voet, Roy Eerlings, Florian Handle, Stefan Prekovic, Elien Smeets, Lisa Moris, Wout Devlies, Claes Ohlsson, Matti Poutanen, Kevin J Verstrepen, Geert Carmeliet, Kaisa-Mari Launonen, Laura Helminen, Jorma J Palvimo, Claude Libert, Dirk Vanderschueren, Christine Helsen, Frank Claessens
The androgen receptor depends on ligand-binding domain dimerization for transcriptional activation. EMBO reports 22 (12) (2021)
Gaëtan Devos, Wout Devlies, Gert De Meerleer, Marcella Baldewijns, Thomas Gevaert, Lisa Moris, Daimantas Milonas, Hendrik van Poppel, Charlien Berghen, Wouter Everaerts, Frank Claessens, Steven Joniau
Neoadjuvant hormonal therapy before radical prostatectomy in high-risk prostate cancer. Nature reviews. Urology 18 (12) (2021)
Anjana Bhardwaj, Abhishek Sohni, Chih-Hong Lou, Karel De Gendt, Fanmao Zhang, Eunah Kim, Subbarayalu Panneerdoss, Waikin Chan, Stefanie Kerkhofs, Frank Claessens, Sarah Kimmins, Manjeet K Rao, Marvin L Meistrich, Miles F Wilkinson
Concordant Androgen-Regulated Expression of Divergent Rhox5 Promoters in Sertoli Cells. Endocrinology 163 (1) (2021)
Florian Handle, Frank Claessens
AR variants: lost in translation to clinical practice? Nature reviews. Urology 16 (8) (2020)
Wout Devlies, Markus Eckstein, Alessia Cimadamore, Gaëtan Devos, Lisa Moris, Thomas Van den Broeck, Rodolfo Montironi, Steven Joniau, Frank Claessens, Thomas Gevaert
Clinical Actionability of the Genomic Landscape of Metastatic Castration Resistant Prostate Cancer. Cells 9 (11) (2020)
Florian Handle, Stefan Prekovic, Christine Helsen, Thomas Van den Broeck, Elien Smeets, Lisa Moris, Roy Eerlings, Sarah El Kharraz, Alfonso Urbanucci, Ian G Mills, Steven Joniau, Gerhardt Attard, Frank Claessens
Drivers of AR indifferent anti-androgen resistance in prostate cancer cells. Scientific reports 9 (1) (2019)
Leen Antonio, S Pauwels, M R Laurent, D Vanschoubroeck, I Jans, J Billen, Frank Claessens, Brigitte Decallonne, Diane De Neubourg, P Vermeersch, Dirk Vanderschueren
Free Testosterone Reflects Metabolic as well as Ovarian Disturbances in Subfertile Oligomenorrheic Women. International journal of endocrinology 2018 (2018)
Thomas Gevaert, Yves-Rémi Van Eycke, Thomas Van den Broeck, Hein Van Poppel, Isabelle Salmon, Sandrine Rorive, Frank Claessens, Dirk De Ridder, Christine Decaestecker, Steven Joniau
Comparing the expression profiles of steroid hormone receptors and stromal cell markers in prostate cancer at different Gleason scores. Scientific reports 8 (1) (2018)
Florian Handle, Martin Puhr, Georg Schaefer, Nicla Lorito, Julia Hoefer, Martina Gruber, Fabian Guggenberger, Frederic Romain Santer, Rute B Marques, Wytske M van Weerden, Frank Claessens, Holger H H Erb, Zoran Culig
The STAT3 Inhibitor Galiellalactone Reduces IL6-Mediated AR Activity in Benign and Malignant Prostate Models. Molecular cancer therapeutics 17 (12) (2018)
Ferran Jardí, Michaël R Laurent, Nari Kim, Rougin Khalil, Dimitri De Bundel, Ann Van Eeckhaut, Lawrence Van Helleputte, Ludo Deboel, Vanessa Dubois, Dieter Schollaert, Brigitte Decallonne, Geert Carmeliet, Ludo Van den Bosch, Rudi D'Hooge, Frank Claessens, Dirk Vanderschueren
Testosterone boosts physical activity in male mice via dopaminergic pathways. Scientific reports 8 (1) (2018)
Marta Nadal, Stefan Prekovic, Nerea Gallastegui, Christine Helsen, Montserrat Abella, Karolina Zielinska, Marina Gay, Marta Vilaseca, Marta Taulès, Adriaan B Houtsmuller, Martin E van Royen, Frank Claessens, Pablo Fuentes-Prior, Eva Estébanez-Perpiñá
Structure of the homodimeric androgen receptor ligand-binding domain. Nature communications 8 (2017)
Thomas Van den Broeck, Steven Joniau, Liesbeth Clinckemalie, Christine Helsen, Stefan Prekovic, Lien Spans, Lorenzo Tosco, Hendrik Van Poppel, Frank Claessens
The role of single nucleotide polymorphisms in predicting prostate cancer risk and therapeutic decision making. BioMed research international 2014 (2014)

Frank Claessens.css-eqlu8i{font-size:small;padding-left:4px;} (F Claessens)

Publication Activity (10 Years)

Top Topics

Top Venues

Frank Claessens (F Claessens)