Christopher J Scott

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 28

Top Topics

Histone Deacetylase

Walled Carbon Nanotubes

Acute Lymphoblastic Leukemia

Top Venues

Molecular pharmaceutics

Journal of materials chemistry. B

Clinical cancer research : an official journal of the American Association for Cancer Research

This page only lists publications with an associated author ORCID identifier.

Publications

Ana M Carvalho, Michelle K Greene, Peter Smyth, Alexander Mutch, Kirsty M McLaughlin, Lauren V Cairns, Ken I Mills, Karen D McCloskey, Christopher J Scott
Development of CD33-Targeted Dual Drug-Loaded Nanoparticles for the Treatment of Pediatric Acute Myeloid Leukemia. Biomacromolecules (2024)
Anas Abed, Michelle K Greene, Alhareth A Alsa'd, Andrea Lees, Andrew Hindley, Daniel B Longley, Simon S McDade, Christopher J Scott
Nanoencapsulation of MDM2 Inhibitor RG7388 and Class-I HDAC Inhibitor Entinostat Enhances their Therapeutic Potential Through Synergistic Antitumor Effects and Reduction of Systemic Toxicity. Molecular pharmaceutics (2024)
Anas Abed, Michelle K Greene, Alhareth A Alsa'd, Andrea Lees, Andrew Hindley, Daniel B Longley, Simon S McDade, Christopher J Scott
Nanoencapsulation of MDM2 Inhibitor RG7388 and Class-I HDAC Inhibitor Entinostat Enhances their Therapeutic Potential Through Synergistic Antitumor Effects and Reduction of Systemic Toxicity. Molecular pharmaceutics 21 (3) (2024)
Irene Shajan, Léa N C Rochet, Shannon R Tracey, Rania Benazza, Bianka Jackowska, Oscar Hernandez-Alba, Sarah Cianférani, Christopher J Scott, Floris L van Delft, Vijay Chudasama, H Bauke Albada
Modular Semisynthetic Approach to Generate T Cell-Dependent Bispecific Constructs from Recombinant IgG1 Antibodies. Bioconjugate chemistry (2024)
Anas Abed, Michelle K Greene, Alhareth A Alsa'd, Andrea Lees, Andrew Hindley, Daniel B Longley, Simon S McDade, Christopher J Scott
Nanoencapsulation of MDM2 Inhibitor RG7388 and Class-I HDAC Inhibitor Entinostat Enhances their Therapeutic Potential Through Synergistic Antitumor Effects and Reduction of Systemic Toxicity. Molecular pharmaceutics 21 (3) (2024)
Anas Abed, Michelle K Greene, Alhareth A Alsa'd, Andrea Lees, Andrew Hindley, Daniel B Longley, Simon S McDade, Christopher J Scott
Nanoencapsulation of MDM2 Inhibitor RG7388 and Class-I HDAC Inhibitor Entinostat Enhances their Therapeutic Potential Through Synergistic Antitumor Effects and Reduction of Systemic Toxicity. Molecular pharmaceutics 21 (3) (2024)
Tista Roy Chaudhuri, Qingxiang Lin, Ewa K Stachowiak, Spencer R Rosario, Joseph A Spernyak, Wen Wee Ma, Michal K Stachowiak, Michelle K Greene, Gerard P Quinn, Simon S McDade, Martin Clynes, Christopher J Scott, Robert M Straubinger
Dual-Hit Strategy for Therapeutic Targeting of Pancreatic Cancer in Patient-Derived Xenograft Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (7) (2024)
Tista Roy Chaudhuri, Qingxiang Lin, Ewa K Stachowiak, Spencer R Rosario, Joseph A Spernyak, Wen Wee Ma, Michal K Stachowiak, Michelle K Greene, Gerard P Quinn, Simon S McDade, Martin Clynes, Christopher J Scott, Robert M Straubinger
Dual-Hit Strategy for Therapeutic Targeting of Pancreatic Cancer in Patient-Derived Xenograft Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (7) (2024)
Tista Roy Chaudhuri, Qingxiang Lin, Ewa K Stachowiak, Spencer R Rosario, Joseph A Spernyak, Wen Wee Ma, Michal K Stachowiak, Michelle K Greene, Gerard P Quinn, Simon S McDade, Martin Clynes, Christopher J Scott, Robert M Straubinger
Dual-hit strategy for therapeutic targeting of pancreatic cancer in patient-derived xenograft tumors. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Tista Roy Chaudhuri, Qingxiang Lin, Ewa K Stachowiak, Spencer R Rosario, Joseph A Spernyak, Wen Wee Ma, Michal K Stachowiak, Michelle K Greene, Gerard P Quinn, Simon S McDade, Martin Clynes, Christopher J Scott, Robert M Straubinger
Dual-hit strategy for therapeutic targeting of pancreatic cancer in patient-derived xenograft tumors. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Tista Roy Chaudhuri, Qingxiang Lin, Ewa K Stachowiak, Spencer R Rosario, Joseph A Spernyak, Wen Wee Ma, Michal K Stachowiak, Michelle K Greene, Gerard P Quinn, Simon S McDade, Martin Clynes, Christopher J Scott, Robert M Straubinger
Dual-Hit Strategy for Therapeutic Targeting of Pancreatic Cancer in Patient-Derived Xenograft Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (7) (2024)
Anas Abed, Michelle K Greene, Alhareth A Alsa'd, Andrea Lees, Andrew Hindley, Daniel B Longley, Simon S McDade, Christopher J Scott
Nanoencapsulation of MDM2 Inhibitor RG7388 and Class-I HDAC Inhibitor Entinostat Enhances their Therapeutic Potential Through Synergistic Antitumor Effects and Reduction of Systemic Toxicity. Molecular pharmaceutics 21 (3) (2024)
Adam Leach, Marie Finnegan, Mariana S Machado, Laura Ferguson, John Steven, Peter Smyth, Andrew Porter, Caroline Barelle, Efrosyni Themistou, Christopher J Scott
Functionalization of polymeric nanoparticles with targeting VNAR ligands using vinyl sulfone conjugation. Journal of materials chemistry. B 11 (19) (2023)
Shannon R Tracey, Peter Smyth, Una M Herron, James F Burrows, Andrew J Porter, Caroline J Barelle, Christopher J Scott
Development of a cationic polyethyleneimine-poly(lactic- co -glycolic acid) nanoparticle system for enhanced intracellular delivery of biologics. RSC advances 13 (48) (2023)
Adam Leach, Marie Finnegan, Mariana S Machado, Laura Ferguson, John Steven, Peter Smyth, Andrew Porter, Caroline Barelle, Efrosyni Themistou, Christopher J Scott
Functionalization of polymeric nanoparticles with targeting VNAR ligands using vinyl sulfone conjugation. Journal of materials chemistry. B (2023)
Adam Leach, Marie Finnegan, Mariana S Machado, Laura Ferguson, John Steven, Peter Smyth, Andrew Porter, Caroline Barelle, Efrosyni Themistou, Christopher J Scott
Functionalization of polymeric nanoparticles with targeting VNAR ligands using vinyl sulfone conjugation. Journal of materials chemistry. B (2023)
Adam Leach, Marie Finnegan, Mariana S Machado, Laura Ferguson, John Steven, Peter Smyth, Andrew Porter, Caroline Barelle, Efrosyni Themistou, Christopher J Scott
Functionalization of polymeric nanoparticles with targeting VNAR ligands using vinyl sulfone conjugation. Journal of materials chemistry. B 11 (19) (2023)
Michelle K Greene, Christopher J Scott
Carbon nanotubes activate inflammatory signalling through binding to Siglec-14. Nature nanotechnology (2023)
Adam Leach, Marie Finnegan, Mariana S Machado, Laura Ferguson, John Steven, Peter Smyth, Andrew Porter, Caroline Barelle, Efrosyni Themistou, Christopher J Scott
Functionalization of polymeric nanoparticles with targeting VNAR ligands using vinyl sulfone conjugation. Journal of materials chemistry. B (2023)
Hajrah Khawaja, Rebecca Briggs, Cheryl H Latimer, Mustasin Rassel, Daryl Griffin, Lyndsey Hanson, Alberto Bardelli, Federica Di Nicolantonio, Simon S McDade, Christopher J Scott, Shauna Lambe, Manisha Maurya, Andreas U Lindner, Jochen H M Prehn, Jose Sousa, Chris Winnington, Melissa J LaBonte, Sarah J Ross, Sandra Van Schaeybroeck
Bcl-xL is a key mediator of apoptosis following KRASG12C inhibition in KRASG12C mutant colorectal cancer. Molecular cancer therapeutics (2022)
Shannon R Tracey, Peter Smyth, Caroline J Barelle, Christopher J Scott
Development of next generation nanomedicine-based approaches for the treatment of cancer: we've barely scratched the surface. Biochemical Society transactions 49 (5) (2022)
Michelle K Greene, João C F Nogueira, Shannon R Tracey, Daniel A Richards, William J McDaid, James F Burrows, Katrina Campbell, Daniel B Longley, Vijay Chudasama, Christopher J Scott
Refined construction of antibody-targeted nanoparticles leads to superior antigen binding and enhanced delivery of an entrapped payload to pancreatic cancer cells. Nanoscale 12 (21) (2021)
William J McDaid, Nikolai Lissin, Ellen Pollheimer, Michelle Greene, Adam Leach, Peter Smyth, Giovanna Bossi, Daniel Longley, David K Cole, Christopher J Scott
Enhanced target-specific delivery of docetaxel-loaded nanoparticles using engineered T cell receptors. Nanoscale 13 (35) (2021)
Michelle K Greene, Ting Chen, Eifion Robinson, Ninfa L Straubinger, Charlene Minx, Darren K W Chan, Jun Wang, James F Burrows, Sandra Van Schaeybroeck, James R Baker, Stephen Caddick, Daniel B Longley, Donald E Mager, Robert M Straubinger, Vijay Chudasama, Christopher J Scott
Controlled coupling of an ultrapotent auristatin warhead to cetuximab yields a next-generation antibody-drug conjugate for EGFR-targeted therapy of KRAS mutant pancreatic cancer. British journal of cancer 123 (10) (2020)
Alaa Al-Hashimi, Vaishnavi Venugopalan, Maren Rehders, Naphannop Sereesongsaeng, Zeynep Hein, Sebastian Springer, Ekkehard Weber, Dagmar Führer, Matthew M Bogyo, Christopher J Scott, Roberta E Burden, Klaudia Brix
Procathepsin V Is Secreted in a TSH Regulated Manner from Human Thyroid Epithelial Cells and Is Accessible to an Activity-Based Probe. International journal of molecular sciences 21 (23) (2020)
Richard D A Wilkinson, Roberta E Burden, Sara H McDowell, Darragh G McArt, Stephen McQuaid, Victoria Bingham, Rich Williams, Órla T Cox, Rosemary O'Connor, Nuala McCabe, Richard D Kennedy, Niamh E Buckley, Christopher J Scott
A Novel Role for Cathepsin S as a Potential Biomarker in Triple Negative Breast Cancer. Journal of oncology 2019 (2019)
William J McDaid, Michelle K Greene, Michael C Johnston, Ellen Pollheimer, Peter Smyth, Kirsty McLaughlin, Sandra Van Schaeybroeck, Robert M Straubinger, Daniel B Longley, Christopher J Scott
Repurposing of Cetuximab in antibody-directed chemotherapy-loaded nanoparticles in EGFR therapy-resistant pancreatic tumours. Nanoscale 11 (42) (2019)
Lai Jiang, Jia Lin, Clifford C Taggart, José A Bengoechea, Christopher J Scott
Nanodelivery strategies for the treatment of multidrug-resistant bacterial infections. Journal of interdisciplinary nanomedicine 3 (3) (2018)