Simon S McDade (Simon McDade)

Scopus Author ID ResearcherID Loop profile Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 22

Top Venues

Clinical cancer research : an official journal of the American Association for Cancer Research

Molecular cancer research : MCR

Molecular cancer therapeutics

Cancer research

Queen's University Belfast (PHD)

This page only lists publications with an associated author ORCID identifier.

Education History

Queen's University Belfast Sep 23 2001 - Dec 10 2004

United Kingdom

PHD :: Oncology Department

Queen's University Belfast Sep 25 1997 - Jul 04 2001

United Kingdom

BSC :: Biology

Publications

Daryl Griffin, Robbie Carson, Deborah Y Moss, Tamas Sessler, Deborah P Lavin, Vijay K Tiwari, Shivaali Karelia, Richard D Kennedy, Kienan I Savage, Simon S McDade, Adam Carie, Jim Pankovich, Mark Bazett, Sandra Van Schaeybroeck
Ruthenium drug BOLD-100 regulates BRAFMT colorectal cancer cell apoptosis through AhR/ROS/ATR signaling axis modulation. Molecular cancer research : MCR (2024)
Daryl Griffin, Robbie Carson, Deborah Y Moss, Tamas Sessler, Deborah P Lavin, Vijay K Tiwari, Shivaali Karelia, Richard D Kennedy, Kienan I Savage, Simon S McDade, Adam Carie, Jim Pankovich, Mark Bazett, Sandra Van Schaeybroeck
Ruthenium drug BOLD-100 regulates BRAFMT colorectal cancer cell apoptosis through AhR/ROS/ATR signaling axis modulation. Molecular cancer research : MCR (2024)
Tista Roy Chaudhuri, Qingxiang Lin, Ewa K Stachowiak, Spencer R Rosario, Joseph A Spernyak, Wen Wee Ma, Michal K Stachowiak, Michelle K Greene, Gerard P Quinn, Simon S McDade, Martin Clynes, Christopher J Scott, Robert M Straubinger
Dual-Hit Strategy for Therapeutic Targeting of Pancreatic Cancer in Patient-Derived Xenograft Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (7) (2024)
Tista Roy Chaudhuri, Qingxiang Lin, Ewa K Stachowiak, Spencer R Rosario, Joseph A Spernyak, Wen Wee Ma, Michal K Stachowiak, Michelle K Greene, Gerard P Quinn, Simon S McDade, Martin Clynes, Christopher J Scott, Robert M Straubinger
Dual-Hit Strategy for Therapeutic Targeting of Pancreatic Cancer in Patient-Derived Xenograft Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (7) (2024)
Tista Roy Chaudhuri, Qingxiang Lin, Ewa K Stachowiak, Spencer R Rosario, Joseph A Spernyak, Wen Wee Ma, Michal K Stachowiak, Michelle K Greene, Gerard P Quinn, Simon S McDade, Martin Clynes, Christopher J Scott, Robert M Straubinger
Dual-hit strategy for therapeutic targeting of pancreatic cancer in patient-derived xenograft tumors. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Tista Roy Chaudhuri, Qingxiang Lin, Ewa K Stachowiak, Spencer R Rosario, Joseph A Spernyak, Wen Wee Ma, Michal K Stachowiak, Michelle K Greene, Gerard P Quinn, Simon S McDade, Martin Clynes, Christopher J Scott, Robert M Straubinger
Dual-hit strategy for therapeutic targeting of pancreatic cancer in patient-derived xenograft tumors. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Tista Roy Chaudhuri, Qingxiang Lin, Ewa K Stachowiak, Spencer R Rosario, Joseph A Spernyak, Wen Wee Ma, Michal K Stachowiak, Michelle K Greene, Gerard P Quinn, Simon S McDade, Martin Clynes, Christopher J Scott, Robert M Straubinger
Dual-Hit Strategy for Therapeutic Targeting of Pancreatic Cancer in Patient-Derived Xenograft Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (7) (2024)
Vera Grinkevitch, Mark Wappett, Nyree T Crawford, Stacey Price, Andrea Lees, Christopher McCann, Katherine McAllister, Jochen H M Prehn, Jamie Young, Jess Bateson, Lewis Gallagher, Magali Michaut, Vivek Iyer, Aikaterini Chatzipli, Syd Barthorpe, Daniel Ciznadija, Ido Sloma, Amy Wesa, David A Tice, Lodewyk F A Wessels, Mathew Garnett, Daniel B Longley, Ultan McDermott, Simon S McDade
Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists. Molecular cancer therapeutics 21 (4) (2022)
Hajrah Khawaja, Rebecca Briggs, Cheryl H Latimer, Mustasin Rassel, Daryl Griffin, Lyndsey Hanson, Alberto Bardelli, Federica Di Nicolantonio, Simon S McDade, Christopher J Scott, Shauna Lambe, Manisha Maurya, Andreas U Lindner, Jochen H M Prehn, Jose Sousa, Chris Winnington, Melissa J LaBonte, Sarah J Ross, Sandra Van Schaeybroeck
Bcl-xL is a key mediator of apoptosis following KRASG12C inhibition in KRASG12C mutant colorectal cancer. Molecular cancer therapeutics (2022)
Ninu Poulose, Nicholas Forsythe, Adam Polonski, Gemma Gregg, Sarah L Maguire, Marc Fuchs, Sarah Minner, Guido Sauter, Simon S McDade, Ian Geoffrey Mills
VPRBP Functions Downstream of the Androgen Receptor and OGT to Restrict p53 Activation in Prostate Cancer. Molecular cancer research : MCR 20 (7) (2022)
Mark Wappett, Adam Harris, Alexander L R Lubbock, Ian Lobb, Simon S McDade, Ian M Overton
SynLeGG: analysis and visualization of multiomics data for discovery of cancer 'Achilles Heels' and gene function relationships. Nucleic acids research 49 (W1) (2021)
Nyree T Crawford, Katie J Stott, Tamas Sessler, Christopher McCann, William McDaid, Andrea Lees, Cheryl Latimer, Jennifer P Fox, Joanne M Munck, Tomoko Smyth, Alpesh Shah, Vanessa Martins, Mark Lawler, Philip David Dunne, Emma M Kerr, Simon S McDade, Victoria Coyle, Daniel B Longley
Clinical Positioning of the IAP Antagonist Tolinapant (ASTX660) in Colorectal Cancer. Molecular cancer therapeutics 20 (9) (2021)
Andrea Lees, Tamas Sessler, Simon S McDade
Dying to Survive-The p53 Paradox. Cancers 13 (13) (2021)
Jerzy A Woznicki, Nisha Saini, Peter Flood, Subhasree Rajaram, Ciaran M Lee, Panagiota Stamou, Agnieszka Skowyra, Milan Bustamante-Garrido, Karine Regazzoni, Nyree Crawford, Simon S McDade, Daniel B Longley, Pedro Aza-Blanc, Fergus Shanahan, Syed A Zulquernain, Jane McCarthy, Silvia Melgar, Bradford L McRae, Ken Nally
TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells. Cell death & disease 12 (10) (2021)
Barrie Peck, Philip Bland, Ioanna Mavrommati, Gareth Muirhead, Hannah Cottom, Patty T Wai, Sarah L Maguire, Holly E Barker, Eamonn Morrison, Divya Kriplani, Lu Yu, Amy Gibson, Giulia Falgari, Keith Brennan, Gillian Farnie, Richard Buus, Rebecca Marlow, Daniela Novo, Eleanor Knight, Naomi Jayne Guppy, Daniela Kolarevic, Snezana Susnjar, Natasa Medic Milijic, Kalnisha Naidoo, Patrycja Gazinska, Ioannis Roxanis, Sunil Pancholi, Lesley-Ann Martin, Erle M Holgersen, Maggie Chon U Cheang, Farzana Noor, Sophie Postel-Vinay, Gerard Quinn, Simon S McDade, Lukas Krasny, Paul Huang, Frances Daley, Fredrik Wallberg, Jyoti S Choudhary, Syed Haider, Andrew N Tutt, Rachael Natrajan
3D Functional Genomics Screens Identify CREBBP as a Targetable Driver in Aggressive Triple-Negative Breast Cancer. Cancer research 81 (4) (2021)
Konstantin Riege, Helene Kretzmer, Arne Sahm, Simon S McDade, Steve Hoffmann, Martin Fischer
Dissecting the DNA binding landscape and gene regulatory network of p63 and p53. eLife 9 (2020)
Luke M Humphreys, Jennifer P Fox, Catherine A Higgins, Joanna Majkut, Tamas Sessler, Kirsty McLaughlin, Christopher McCann, Jamie Z Roberts, Nyree T Crawford, Simon S McDade, Christopher J Scott, Timothy Harrison, Daniel B Longley
A revised model of TRAIL-R2 DISC assembly explains how FLIP(L) can inhibit or promote apoptosis. EMBO reports 21 (3) (2020)
Andrea Lees, Alexander J McIntyre, Nyree T Crawford, Fiammetta Falcone, Christopher McCann, Caitriona Holohan, Gerard P Quinn, Jamie Z Roberts, Tamas Sessler, Peter F Gallagher, Gemma M A Gregg, Katherine McAllister, Kirsty M McLaughlin, Wendy L Allen, Laurence J Egan, Aideen E Ryan, Melissa J Labonte-Wilson, Philip David Dunne, Mark Wappett, Vicky M Coyle, Patrick G Johnston, Emma M Kerr, Daniel B Longley, Simon S McDade
The pseudo-caspase FLIP(L) regulates cell fate following p53 activation. Proceedings of the National Academy of Sciences of the United States of America 117 (30) (2020)
Charles M Haughey, Debayan Mukherjee, Rebecca E Steele, Amy Popple, Lara Dura-Perez, Adam Pickard, Mehjabin Patel, Suneil Jain, Paul B Mullan, Rich Williams, Pedro Oliveira, Niamh E Buckley, Jamie Honeychurch, Simon S McDade, Timothy Illidge, Ian Geoffrey Mills, Sharon L Eddie
Investigating Radiotherapy Response in a Novel Syngeneic Model of Prostate Cancer. Cancers 12 (10) (2020)
Jennifer Ferris, Margarita Espona-Fiedler, Claudia Hamilton, Caitriona Holohan, Nyree T Crawford, Alex J McIntyre, Jamie Z Roberts, Mark Wappett, Simon S McDade, Daniel B Longley, Victoria Coyle
Pevonedistat (MLN4924): mechanism of cell death induction and therapeutic potential in colorectal cancer. Cell death discovery 6 (2020)
Stephanie G Craig, Lesley A Anderson, Michael Moran, Laura Graham, Keith Currie, Keith Rooney, Max Robinson, Victoria Bingham, Kate S Cuschieri, Stephen McQuaid, Andrew Graeme Schache, Terence M Jones, Dennis McCance, Manuel Salto-Tellez, Simon S McDade, Jacqueline A James
Comparison of Molecular Assays for HPV Testing in Oropharyngeal Squamous Cell Carcinomas: A Population-Based Study in Northern Ireland. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 29 (1) (2019)
Alan R Gilmore, Matthew Alderdice, Kienan I Savage, Paul G O'Reilly, Aideen C Roddy, Philip David Dunne, Mark Lawler, Simon S McDade, David J Waugh, Darragh G McArt
ACE: A Workbench Using Evolutionary Genetic Algorithms for Analyzing Association in TCGA. Cancer research 79 (8) (2019)

Simon S McDade.css-eqlu8i{font-size:small;padding-left:4px;} (Simon McDade)

Publication Activity (10 Years)

Top Topics

Top Venues

Simon S McDade (Simon McDade)