Craig A Townsend

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 31

Top Topics

Acinetobacter Baumannii

Top Venues

ACS chemical biology

Chembiochem : a European journal of chemical biology

Proceedings of the National Academy of Sciences of the United States of America

Nature chemical biology

This page only lists publications with an associated author ORCID identifier.

Publications

Lukas Kahlert, Michael S Lichstrahl, Craig A Townsend
Colorimetric Determination of Adenylation Domain Activity in Nonribosomal Peptide Synthetases by Using Chrome Azurol S. Chembiochem : a European journal of chemical biology 24 (5) (2023)
Michael S Lichstrahl, Lukas Kahlert, Rongfeng Li, Trevor A Zandi, Jerry Yang, Craig A Townsend
Synthesis of functionalized 2,3-diaminopropionates and their potential for directed monobactam biosynthesis. Chemical science 14 (14) (2023)
Paramita Pal, Jamie R Alley, Craig A Townsend
Examining Heterodimerization by Aryl C-N Coupling in Dynemicin Biosynthesis. ACS chemical biology 18 (2) (2023)
Paramita Pal, Jamie R Alley, Craig A Townsend
Examining Heterodimerization by Aryl C-N Coupling in Dynemicin Biosynthesis. ACS chemical biology 18 (2) (2023)
Paramita Pal, Jamie R Alley, Craig A Townsend
Examining Heterodimerization by Aryl C-N Coupling in Dynemicin Biosynthesis. ACS chemical biology 18 (2) (2023)
Paramita Pal, Jamie R Alley, Craig A Townsend
Examining Heterodimerization by Aryl C-N Coupling in Dynemicin Biosynthesis. ACS chemical biology (2023)
Lukas Kahlert, Michael S Lichstrahl, Craig A Townsend
Colorimetric Determination of Adenylation Domain Activity in Nonribosomal Peptide Synthetases by Using Chrome Azurol S. Chembiochem : a European journal of chemical biology 24 (5) (2023)
Paramita Pal, Jamie R Alley, Douglas R Cohen, Craig A Townsend
Dynemicin A Derivatives as Potential Cancer Chemotherapeutics by Mutasynthesis. Helvetica chimica acta 106 (12) (2023)
Lukas Kahlert, Michael S Lichstrahl, Craig A Townsend
Colorimetric Determination of Adenylation Domain Activity in Nonribosomal Peptide Synthetases by Using Chrome Azurol S. Chembiochem : a European journal of chemical biology 24 (5) (2023)
Paramita Pal, Jamie R Alley, Craig A Townsend
Examining Heterodimerization by Aryl C-N Coupling in Dynemicin Biosynthesis. ACS chemical biology 18 (2) (2023)
Paramita Pal, Serena M L Wessely, Craig A Townsend
Normal and Aberrant Methyltransferase Activities Give Insights into the Final Steps of Dynemicin A Biosynthesis. Journal of the American Chemical Society (2023)
Esther J Han, Seoung Rak Lee, Craig A Townsend, Mohammad R Seyedsayamdost
Targeted Discovery of Cryptic Enediyne Natural Products via FRET-Coupled High-Throughput Elicitor Screening. ACS chemical biology (2023)
Hunter R Batchelder, Trevor A Zandi, Amit Kaushik, Akul Naik, Elizabeth Story-Roller, Emily C Maggioncalda, Gyanu Lamichhane, Eric L Nuermberger, Craig A Townsend
Structure-Activity Relationship of Penem Antibiotic Side Chains Used against Mycobacteria Reveals Highly Active Compounds. ACS infectious diseases 8 (8) (2022)
Michael S Lichstrahl, Craig A Townsend, Erica K Sinner
Stereochemical course of cobalamin-dependent radical SAM methylation by TokK and ThnK. RSC chemical biology 3 (8) (2022)
Michael J Wheadon, Craig A Townsend
Accurate Substrate-Like Probes for Trapping Late-Stage Intermediates in Nonribosomal Peptide Synthetase Condensation Domains. ACS chemical biology 17 (8) (2022)
Feng Li, Zhenjian Lin, Joshua P Torres, Eric A Hill, De-Hai Li, Craig A Townsend, Eric W Schmidt
Sea Urchin Polyketide Synthase SpPks1 Produces the Naphthalene Precursor to Echinoderm Pigments. Journal of the American Chemical Society 144 (21) (2022)
Hayley L Knox, Erica K Sinner, Craig A Townsend, Amie K Boal, Squire J Booker
Structure of a B 12 -dependent radical SAM enzyme in carbapenem biosynthesis. Nature 602 (7896) (2022)
Erica K Sinner, Rongfeng Li, Daniel R Marous, Craig A Townsend
ThnL, a B12-dependent radical S -adenosylmethionine enzyme, catalyzes thioether bond formation in carbapenem biosynthesis. Proceedings of the National Academy of Sciences of the United States of America 119 (34) (2022)
Lukas Kahlert, Michael S Lichstrahl, Craig A Townsend
Colorimetric Determination of Adenylation Domain Activity in Nonribosomal Peptide Synthetases by Using Chrome Azurol S. Chembiochem : a European journal of chemical biology (2022)
Darcie H Long, Craig A Townsend
Acyl Donor Stringency and Dehydroaminoacyl Intermediates in β-Lactam Formation by a Non-ribosomal Peptide Synthetase. ACS chemical biology 16 (5) (2021)
Michael J Wheadon, Craig A Townsend
Evolutionary and functional analysis of an NRPS condensation domain integrates β-lactam, ᴅ-amino acid, and dehydroamino acid synthesis. Proceedings of the National Academy of Sciences of the United States of America 118 (17) (2021)
Trevor A Zandi, Craig A Townsend
Competing off-loading mechanisms of meropenem from an l,d-transpeptidase reduce antibiotic effectiveness. Proceedings of the National Academy of Sciences of the United States of America 118 (27) (2021)
Douglas R Cohen, Craig A Townsend
C-N-Coupled Metabolites Yield Insights into Dynemicin A Biosynthesis. Chembiochem : a European journal of chemical biology 21 (15) (2020)
Hunter R Batchelder, Elizabeth Story-Roller, Evan P Lloyd, Amit Kaushik, Kristina M Bigelow, Emily C Maggioncalda, Eric L Nuermberger, Gyanu Lamichhane, Craig A Townsend
Development of a penem antibiotic against Mycobacteroides abscessus. Communications biology 3 (1) (2020)
Ketan D Patel, Felipe B d'Andrea, Nicole M Gaudelli, Andrew R Buller, Craig A Townsend, Andrew M Gulick
Structure of a bound peptide phosphonate reveals the mechanism of nocardicin bifunctional thioesterase epimerase-hydrolase half-reactions. Nature communications 10 (1) (2019)
Darcie H Long, Craig A Townsend
Mechanism of Integrated β-Lactam Formation by a Nonribosomal Peptide Synthetase during Antibiotic Synthesis. Biochemistry 57 (24) (2018)
Dominik A Herbst, Callie R Huitt-Roehl, Roman Peter Jakob, Jacob M Kravetz, Philip A Storm, Jamie R Alley, Craig A Townsend, Timm Maier
The structural organization of substrate loading in iterative polyketide synthases. Nature chemical biology 14 (5) (2018)
Douglas R Cohen, Craig A Townsend
Characterization of an Anthracene Intermediate in Dynemicin Biosynthesis. Angewandte Chemie (International ed. in English) 57 (20) (2018)
Philip A Storm, Paramita Pal, Callie R Huitt-Roehl, Craig A Townsend
Exploring Fungal Polyketide C-Methylation through Combinatorial Domain Swaps. ACS chemical biology 13 (11) (2018)
Ryan A Oliver, Rongfeng Li, Craig A Townsend
Monobactam formation in sulfazecin by a nonribosomal peptide synthetase thioesterase. Nature chemical biology 14 (1) (2017)
Douglas R Cohen, Craig A Townsend
A dual role for a polyketide synthase in dynemicin enediyne and anthraquinone biosynthesis. Nature chemistry 10 (2) (2017)