Mohammad R Seyedsayamdost

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 76

Top Topics

Pseudomonas Aeruginosa

Mass Spectrometry

Top Venues

Journal of the American Chemical Society

ACS chemical biology

Angewandte Chemie (International ed. in English)

Nature chemical biology

This page only lists publications with an associated author ORCID identifier.

Publications

Esther J Han, Myungeun Jeong, Seoung Rak Lee, Erik J Sorensen, Mohammad R Seyedsayamdost
Hirocidins, Cytotoxic Metabolites from Streptomyces hiroshimensis, Induce Mitochondrion-Mediated Apoptosis. Angewandte Chemie (International ed. in English) (2024)
Vasiliki T Chioti, Kenzie A Clark, Jack G Ganley, Esther J Han, Mohammad R Seyedsayamdost
N-Cα Bond Cleavage Catalyzed by a Multinuclear Iron Oxygenase from a Divergent Methanobactin-like RiPP Gene Cluster. Journal of the American Chemical Society 146 (11) (2024)
Vasiliki T Chioti, Kenzie A Clark, Jack G Ganley, Esther J Han, Mohammad R Seyedsayamdost
N-Cα Bond Cleavage Catalyzed by a Multinuclear Iron Oxygenase from a Divergent Methanobactin-like RiPP Gene Cluster. Journal of the American Chemical Society (2024)
Vasiliki T Chioti, Kenzie A Clark, Jack G Ganley, Esther J Han, Mohammad R Seyedsayamdost
N-Cα Bond Cleavage Catalyzed by a Multinuclear Iron Oxygenase from a Divergent Methanobactin-like RiPP Gene Cluster. Journal of the American Chemical Society 146 (11) (2024)
Vasiliki T Chioti, Kenzie A Clark, Jack G Ganley, Esther J Han, Mohammad R Seyedsayamdost
N-Cα Bond Cleavage Catalyzed by a Multinuclear Iron Oxygenase from a Divergent Methanobactin-like RiPP Gene Cluster. Journal of the American Chemical Society (2024)
Andy K L Nguy, Ryan J Martinie, Amanda Cai, Mohammad R Seyedsayamdost
Detection of a Kinetically Competent Compound-I Intermediate in the Vancomycin Biosynthetic Enzyme OxyB. Journal of the American Chemical Society 146 (29) (2024)
Vasiliki T Chioti, Kirklin L McWhorter, Tamra C Blue, Yuchen Li, Fei Xu, Philip D Jeffrey, Katherine M Davis, Mohammad R Seyedsayamdost
Potent and specific antibiotic combination therapy against Clostridioides difficile. Nature chemical biology 20 (7) (2024)
Vasiliki T Chioti, Kenzie A Clark, Jack G Ganley, Esther J Han, Mohammad R Seyedsayamdost
N-Cα Bond Cleavage Catalyzed by a Multinuclear Iron Oxygenase from a Divergent Methanobactin-like RiPP Gene Cluster. Journal of the American Chemical Society 146 (11) (2024)
Vasiliki T Chioti, Kenzie A Clark, Jack G Ganley, Esther J Han, Mohammad R Seyedsayamdost
N-Cα Bond Cleavage Catalyzed by a Multinuclear Iron Oxygenase from a Divergent Methanobactin-like RiPP Gene Cluster. Journal of the American Chemical Society 146 (11) (2024)
Brooke A Johnson, Kenzie A Clark, Leah B Bushin, Calvin N Spolar, Mohammad R Seyedsayamdost
Expanding the Landscape of Noncanonical Amino Acids in RiPP Biosynthesis. Journal of the American Chemical Society 146 (6) (2024)
Vasiliki T Chioti, Kirklin L McWhorter, Tamra C Blue, Yuchen Li, Fei Xu, Philip D Jeffrey, Katherine M Davis, Mohammad R Seyedsayamdost
Potent and specific antibiotic combination therapy against Clostridioides difficile. Nature chemical biology 20 (7) (2024)
Chen Zhang, Mohammad R Seyedsayamdost
Widespread Peptide Surfactants with Post-translational C -methylations Promote Bacterial Development. bioRxiv : the preprint server for biology (2024)
Vasiliki T Chioti, Kenzie A Clark, Jack G Ganley, Esther J Han, Mohammad R Seyedsayamdost
N-Cα Bond Cleavage Catalyzed by a Multinuclear Iron Oxygenase from a Divergent Methanobactin-like RiPP Gene Cluster. Journal of the American Chemical Society 146 (11) (2024)
Vasiliki T Chioti, Kirklin L McWhorter, Tamra C Blue, Yuchen Li, Fei Xu, Philip D Jeffrey, Katherine M Davis, Mohammad R Seyedsayamdost
Potent and specific antibiotic combination therapy against Clostridioides difficile. Nature chemical biology 20 (7) (2024)
Brooke A Johnson, Kenzie A Clark, Leah B Bushin, Calvin N Spolar, Mohammad R Seyedsayamdost
Expanding the Landscape of Noncanonical Amino Acids in RiPP Biosynthesis. Journal of the American Chemical Society 146 (6) (2024)
Chase M Kayrouz, Kendra A Ireland, Vanessa Y Ying, Katherine M Davis, Mohammad R Seyedsayamdost
Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution. Nature chemistry (2024)
Chase M Kayrouz, Kendra A Ireland, Vanessa Y Ying, Katherine M Davis, Mohammad R Seyedsayamdost
Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution. Nature chemistry (2024)
Vasiliki T Chioti, Kenzie A Clark, Jack G Ganley, Esther J Han, Mohammad R Seyedsayamdost
N-Cα Bond Cleavage Catalyzed by a Multinuclear Iron Oxygenase from a Divergent Methanobactin-like RiPP Gene Cluster. Journal of the American Chemical Society 146 (11) (2024)
Brooke A Johnson, Kenzie A Clark, Leah B Bushin, Calvin N Spolar, Mohammad R Seyedsayamdost
Expanding the Landscape of Noncanonical Amino Acids in RiPP Biosynthesis. Journal of the American Chemical Society 146 (6) (2024)
Esther J Han, Myungeun Jeong, Seoung Rak Lee, Erik J Sorensen, Mohammad R Seyedsayamdost
Hirocidins, Cytotoxic Metabolites from Streptomyces hiroshimensis, Induce Mitochondrion-Mediated Apoptosis. Angewandte Chemie (International ed. in English) 63 (37) (2024)
Brooke A Johnson, Kenzie A Clark, Leah B Bushin, Calvin N Spolar, Mohammad R Seyedsayamdost
Expanding the Landscape of Noncanonical Amino Acids in RiPP Biosynthesis. Journal of the American Chemical Society (2024)
Vasiliki T Chioti, Kirklin L McWhorter, Tamra C Blue, Yuchen Li, Fei Xu, Philip D Jeffrey, Katherine M Davis, Mohammad R Seyedsayamdost
Potent and specific antibiotic combination therapy against Clostridioides difficile. Nature chemical biology 20 (7) (2024)
Andy K L Nguy, Ryan J Martinie, Amanda Cai, Mohammad R Seyedsayamdost
Detection of a Kinetically Competent Compound-I Intermediate in the Vancomycin Biosynthetic Enzyme OxyB. Journal of the American Chemical Society (2024)
Vasiliki T Chioti, Kenzie A Clark, Jack G Ganley, Esther J Han, Mohammad R Seyedsayamdost
N-Cα Bond Cleavage Catalyzed by a Multinuclear Iron Oxygenase from a Divergent Methanobactin-like RiPP Gene Cluster. Journal of the American Chemical Society 146 (11) (2024)
Chen Zhang, Mohammad R Seyedsayamdost
Widespread Peptide Surfactants with Post-translational C- methylations Promote Bacterial Development. bioRxiv : the preprint server for biology (2024)
Kendra A Ireland, Chase M Kayrouz, Jonathan Huang, Mohammad R Seyedsayamdost, Katherine M Davis
Structural Characterization and Ligand-Induced Conformational Changes of SenB, a Se-Glycosyltransferase Involved in Selenoneine Biosynthesis. Biochemistry (2023)
Nicole Hauser, Kendra A Ireland, Vasiliki T Chioti, Clarissa C Forneris, Katherine M Davis, Mohammad R Seyedsayamdost
Robust Chemoenzymatic Synthesis of Keratinimicin Aglycone Analogues Facilitated by the Structure and Selectivity of OxyB. ACS chemical biology (2023)
Esther J Han, Seoung Rak Lee, Craig A Townsend, Mohammad R Seyedsayamdost
Targeted Discovery of Cryptic Enediyne Natural Products via FRET-Coupled High-Throughput Elicitor Screening. ACS chemical biology (2023)
Samantha M Horwitz, Tamra C Blue, Joseph A Ambarian, Shotaro Hoshino, Mohammad R Seyedsayamdost, Katherine M Davis
Structural insights into inhibition of the drug target dihydroorotate dehydrogenase by bacterial hydroxyalkylquinolines. RSC chemical biology 3 (4) (2022)
Chase M Kayrouz, Jonathan Huang, Nicole Hauser, Mohammad R Seyedsayamdost
Biosynthesis of selenium-containing small molecules in diverse microorganisms. Nature 610 (7930) (2022)
Kenzie A Clark, Brett C Covington, Mohammad R Seyedsayamdost
Biosynthesis-guided discovery reveals enteropeptins as alternative sactipeptides containing N-methylornithine. Nature chemistry (2022)
Kenzie A Clark, Mohammad R Seyedsayamdost
Bioinformatic Atlas of Radical SAM Enzyme-Modified RiPP Natural Products Reveals an Isoleucine-Tryptophan Crosslink. Journal of the American Chemical Society 144 (39) (2022)
Seoung Rak Lee, Mohammad R Seyedsayamdost
Induction of Diverse Cryptic Fungal Metabolites by Steroids and Channel Blockers. Angewandte Chemie (International ed. in English) 61 (29) (2022)
Leah B Bushin, Brett C Covington, Kenzie A Clark, Alessio Caruso, Mohammad R Seyedsayamdost
Bicyclostreptins are radical SAM enzyme-modified peptides with unique cyclization motifs. Nature chemical biology 18 (10) (2022)
Kenzie A Clark, Leah B Bushin, Mohammad R Seyedsayamdost
RaS-RiPPs in Streptococci and the Human Microbiome. ACS bio & med chem Au 2 (4) (2022)
Brett C Covington, Mohammad R Seyedsayamdost
Vitamin B3 Triggers Biosynthesis of Secondary Metabolite Dormancy Signals in Streptococcus suis . Journal of the American Chemical Society 144 (33) (2022)
Yuchen Li, Seoung Rak Lee, Esther J Han, Mohammad R Seyedsayamdost
Momomycin, an Antiproliferative Cryptic Metabolite from the Oxytetracycline Producer Streptomyces rimosus. Angewandte Chemie (International ed. in English) 61 (39) (2022)
Esther J Han, Seoung Rak Lee, Shotaro Hoshino, Mohammad R Seyedsayamdost
Targeted Discovery of Cryptic Metabolites with Antiproliferative Activity. ACS chemical biology 17 (11) (2022)
Mohammad R Seyedsayamdost, Pierre Stallforth
Special Issue in Honor of Professor Jon Clardy. Journal of natural products 83 (3) (2021)
Alessio Caruso, Mohammad R Seyedsayamdost
Radical SAM Enzyme QmpB Installs Two 9-Membered Ring Sactionine Macrocycles during Biogenesis of a Ribosomal Peptide Natural Product. The Journal of organic chemistry 86 (16) (2021)
Jong-Duk Park, Yuchen Li, Kyuho Moon, Esther J Han, Seoung Rak Lee, Mohammad R Seyedsayamdost
Structural Elucidation of Cryptic Algaecides in Marine Algal-Bacterial Symbioses by NMR Spectroscopy and MicroED. Angewandte Chemie (International ed. in English) (2021)
Brett C Covington, Mohammad R Seyedsayamdost
MetEx, a Metabolomics Explorer Application for Natural Product Discovery. ACS chemical biology (2021)
Anran Li, Bethany K Okada, Paul C Rosen, Mohammad R Seyedsayamdost
Piperacillin triggers virulence factor biosynthesis via the oxidative stress response in Burkholderia thailandensis. Proceedings of the National Academy of Sciences of the United States of America 118 (26) (2021)
Aidin R Balo, Alessio Caruso, Lizhi Tao, Dean J Tantillo, Mohammad R Seyedsayamdost, R David Britt
Trapping a cross-linked lysine-tryptophan radical in the catalytic cycle of the radical SAM enzyme SuiB. Proceedings of the National Academy of Sciences of the United States of America 118 (21) (2021)
Jong-Duk Park, Kyuho Moon, Cheryl Miller, Jessica Rose, Fei Xu, Christopher C Ebmeier, Jeremy R Jacobsen, Dainan Mao, William M Old, David DeShazer, Mohammad R Seyedsayamdost
Thailandenes, Cryptic Polyene Natural Products Isolated from Burkholderia thailandensis Using Phenotype-Guided Transposon Mutagenesis. ACS chemical biology 15 (5) (2020)
E. Peter Greenberg, Josephine R Chandler, Mohammad R Seyedsayamdost
The Chemistry and Biology of Bactobolin: A 10-Year Collaboration with Natural Product Chemist Extraordinaire Jon Clardy. Journal of natural products 83 (3) (2020)
Chen Zhang, Mohammad R Seyedsayamdost
Discovery of a Cryptic Depsipeptide from Streptomyces ghanaensis via MALDI-MS-Guided High-Throughput Elicitor Screening. Angewandte Chemie (International ed. in English) 59 (51) (2020)
Yen-Chih Chen, Mohammad R Seyedsayamdost, Niels Ringstad
A microbial metabolite synergizes with endogenous serotonin to trigger C. elegans reproductive behavior. Proceedings of the National Academy of Sciences of the United States of America 117 (48) (2020)
Dainan Mao, Aya Yoshimura, Rurun Wang, Mohammad R Seyedsayamdost
Reporter-Guided Transposon Mutant Selection for Activation of Silent Gene Clusters in Burkholderia thailandensis. Chembiochem : a European journal of chemical biology 21 (13) (2020)
Clarissa C Forneris, Andy K L Nguy, Mohammad R Seyedsayamdost
Mapping and Exploiting the Promiscuity of OxyB toward the Biocatalytic Production of Vancomycin Aglycone Variants. ACS catalysis 10 (16) (2020)
Chen Zhang, Mohammad R Seyedsayamdost
CanE, an Iron/2-Oxoglutarate-Dependent Lasso Peptide Hydroxylase from Streptomyces canus. ACS chemical biology 15 (4) (2020)
Leah B Bushin, Brett C Covington, Britta E Rued, Michael J Federle, Mohammad R Seyedsayamdost
Discovery and Biosynthesis of Streptosactin, a Sactipeptide with an Alternative Topology Encoded by Commensal Bacteria in the Human Microbiome. Journal of the American Chemical Society 142 (38) (2020)
Aya Yoshimura, Brett C Covington, Étienne Gallant, Chen Zhang, Anran Li, Mohammad R Seyedsayamdost
Unlocking Cryptic Metabolites with Mass Spectrometry-Guided Transposon Mutant Selection. ACS chemical biology 15 (10) (2020)
Geoffrey D Vrla, Mark Esposito, Chen Zhang, Yibin Kang, Mohammad R Seyedsayamdost, Zemer Gitai
Cytotoxic alkyl-quinolones mediate surface-induced virulence in Pseudomonas aeruginosa. PLoS pathogens 16 (9) (2020)
Kenzie A Clark, Leah B Bushin, Mohammad R Seyedsayamdost
Aliphatic Ether Bond Formation Expands the Scope of Radical SAM Enzymes in Natural Product Biosynthesis. Journal of the American Chemical Society 141 (27) (2019)
Kyuho Moon, Fei Xu, Chen Zhang, Mohammad R Seyedsayamdost
Bioactivity-HiTES Unveils Cryptic Antibiotics Encoded in Actinomycete Bacteria. ACS chemical biology 14 (4) (2019)
Mohammad R Seyedsayamdost
Toward a global picture of bacterial secondary metabolism. Journal of industrial microbiology & biotechnology 46 (3-4) (2019)
Bethany K Okada, Anran Li, Mohammad R Seyedsayamdost
Identification of the Hypertension Drug Guanfacine as an Antivirulence Agent in Pseudomonas aeruginosa. Chembiochem : a European journal of chemical biology 20 (15) (2019)
Fei Xu, Yihan Wu, Chen Zhang, Katherine M Davis, Kyuho Moon, Leah B Bushin, Mohammad R Seyedsayamdost
A genetics-free method for high-throughput discovery of cryptic microbial metabolites. Nature chemical biology 15 (2) (2019)
Kyuho Moon, Fei Xu, Mohammad R Seyedsayamdost
Cebulantin, a Cryptic Lanthipeptide Antibiotic Uncovered Using Bioactivity-Coupled HiTES. Angewandte Chemie (International ed. in English) 58 (18) (2019)
Nicholas A Isley, Yusuke Endo, Zhi-Chen Wu, Brett C Covington, Leah B Bushin, Mohammad R Seyedsayamdost, Dale L Boger
Total Synthesis and Stereochemical Assignment of Streptide. Journal of the American Chemical Society 141 (43) (2019)
Alessio Caruso, Ryan J Martinie, Leah B Bushin, Mohammad R Seyedsayamdost
Macrocyclization via an Arginine-Tyrosine Crosslink Broadens the Reaction Scope of Radical S-Adenosylmethionine Enzymes. Journal of the American Chemical Society 141 (42) (2019)
Leah B Bushin, Kenzie A Clark, István Pelczer, Mohammad R Seyedsayamdost
Charting an Unexplored Streptococcal Biosynthetic Landscape Reveals a Unique Peptide Cyclization Motif. Journal of the American Chemical Society 140 (50) (2018)
JoAnne Stubbe, Mohammad R Seyedsayamdost
Discovery of a New Class I Ribonucleotide Reductase with an Essential DOPA Radical and NO Metal as an Initiator of Long-Range Radical Transfer. Biochemistry 58 (6) (2018)
Seyma Ozturk, Clarissa C Forneris, Andy K L Nguy, Erik J Sorensen, Mohammad R Seyedsayamdost
Modulating OxyB-Catalyzed Cross-Coupling Reactions in Vancomycin Biosynthesis by Incorporation of Diverse d-Tyr Analogues. The Journal of organic chemistry 83 (13) (2018)
Alessio Caruso, Leah B Bushin, Kenzie A Clark, Ryan J Martinie, Mohammad R Seyedsayamdost
Radical Approach to Enzymatic β-Thioether Bond Formation. Journal of the American Chemical Society 141 (2) (2018)
Clarissa C Forneris, Mohammad R Seyedsayamdost
In Vitro Reconstitution of OxyC Activity Enables Total Chemoenzymatic Syntheses of Vancomycin Aglycone Variants. Angewandte Chemie (International ed. in English) 57 (27) (2018)
Kelsey R Schramma, Clarissa C Forneris, Alessio Caruso, Mohammad R Seyedsayamdost
Mechanistic Investigations of Lysine-Tryptophan Cross-Link Formation Catalyzed by Streptococcal Radical S-Adenosylmethionine Enzymes. Biochemistry 57 (4) (2018)
Yihan Wu, Mohammad R Seyedsayamdost
The Polyene Natural Product Thailandamide A Inhibits Fatty Acid Biosynthesis in Gram-Positive and Gram-Negative Bacteria. Biochemistry 57 (29) (2018)
Kelsey R Schramma, Mohammad R Seyedsayamdost
Lysine-Tryptophan-Crosslinked Peptides Produced by Radical SAM Enzymes in Pathogenic Streptococci. ACS chemical biology 12 (4) (2017)
Fei Xu, Behnam Nazari, Kyuho Moon, Leah B Bushin, Mohammad R Seyedsayamdost
Discovery of a Cryptic Antifungal Compound from Streptomyces albus J1074 Using High-Throughput Elicitor Screens. Journal of the American Chemical Society 139 (27) (2017)
Behnam Nazari, Clarissa C Forneris, Marcus I Gibson, Kyuho Moon, Kelsey R Schramma, Mohammad R Seyedsayamdost
Nonomuraea sp. ATCC 55076 harbours the largest actinomycete chromosome to date and the kistamicin biosynthetic gene cluster. MedChemComm 8 (4) (2017)
Paul C Rosen, Mohammad R Seyedsayamdost
Though Much Is Taken, Much Abides: Finding New Antibiotics Using Old Ones. Biochemistry 56 (37) (2017)
Clarissa C Forneris, Seyma Ozturk, Marcus I Gibson, Erik J Sorensen, Mohammad R Seyedsayamdost
In Vitro Reconstitution of OxyA Enzymatic Activity Clarifies Late Steps in Vancomycin Biosynthesis. ACS chemical biology 12 (9) (2017)
Oliver Baars, Xinning Zhang, Marcus I Gibson, Alan T Stone, François M M Morel, Mohammad R Seyedsayamdost
Crochelins: Siderophores with an Unprecedented Iron-Chelating Moiety from the Nitrogen-Fixing Bacterium Azotobacter chroococcum. Angewandte Chemie (International ed. in English) 57 (2) (2017)
Rurun Wang, Mohammad R Seyedsayamdost
Roseochelin B, an Algaecidal Natural Product Synthesized by the Roseobacter Phaeobacter inhibens in Response to Algal Sinapic Acid. Organic letters 19 (19) (2017)