Laura H Heitman (Daan van der Es)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 20

Top Topics

Monoclonal Antibody

Histone Deacetylase

Crystal Structure

Binding Protein

Top Venues

ACS chemical biology

Journal of medicinal chemistry

Nature communications

Purinergic signalling

This page only lists publications with an associated author ORCID identifier.

Publications

Natalia V Ortiz Zacarías, Sascha Röth, Jeremy D Broekhuis, Laura H Heitman, Kevin Moreau, Laura H Heitman
Inducing Receptor Degradation as a Novel Approach to Target CC Chemokine Receptor 2 (CCR2). International journal of molecular sciences 25 (16) (2024)
Bert L H Beerkens, Vasiliki Andrianopoulou, Xuesong Wang, Rongfang Liu, Gerard van Westen, Willem Jespers, Adriaan P IJzerman, Laura H Heitman, Laura H Heitman
N -Acyl- N -Alkyl Sulfonamide Probes for Ligand-Directed Covalent Labeling of GPCRs: The Adenosine A 2B Receptor as Case Study. ACS chemical biology 19 (7) (2024)
Bert L H Beerkens, Vasiliki Andrianopoulou, Xuesong Wang, Rongfang Liu, Gerard van Westen, Willem Jespers, Adriaan P IJzerman, Laura H Heitman, Laura H Heitman
N -Acyl- N -Alkyl Sulfonamide Probes for Ligand-Directed Covalent Labeling of GPCRs: The Adenosine A 2B Receptor as Case Study. ACS chemical biology (2024)
Bert L H Beerkens, Vasiliki Andrianopoulou, Xuesong Wang, Rongfang Liu, Gerard van Westen, Willem Jespers, Adriaan P IJzerman, Laura H Heitman, Laura H Heitman
N -Acyl- N -Alkyl Sulfonamide Probes for Ligand-Directed Covalent Labeling of GPCRs: The Adenosine A 2B Receptor as Case Study. ACS chemical biology 19 (7) (2024)
Lisa S den Hollander, Bert L H Beerkens, Sebastian Dekkers, Jacobus P D van Veldhoven, Natalia V Ortiz Zacarías, Cas van der Horst, Elisabeth G Sieders, Bert de Valk, Jianhui Wang, Adriaan P IJzerman, Laura H Heitman, Laura H Heitman
Labeling of CC Chemokine Receptor 2 with a Versatile Intracellular Allosteric Probe. ACS chemical biology (2024)
Majlen A Dilweg, Marina Gorostiola González, Martijn D de Ruiter, Nadine J Meijboom, Jacobus P D van Veldhoven, Rongfang Liu, Willem Jespers, Gerard van Westen, Laura H Heitman, Adriaan P IJzerman, Laura H Heitman
Exploring novel dilazep derivatives as hENT1 inhibitors and potentially covalent molecular tools. Purinergic signalling (2024)
Lisa S den Hollander, Bert L H Beerkens, Sebastian Dekkers, Jacobus P D van Veldhoven, Natalia V Ortiz Zacarías, Cas van der Horst, Elisabeth G Sieders, Bert de Valk, Jianhui Wang, Adriaan P IJzerman, Laura H Heitman, Laura H Heitman
Labeling of CC Chemokine Receptor 2 with a Versatile Intracellular Allosteric Probe. ACS chemical biology (2024)
Natalia V Ortiz Zacarías, Sascha Röth, Jeremy D Broekhuis, Laura H Heitman, Kevin Moreau, Laura H Heitman
Inducing Receptor Degradation as a Novel Approach to Target CC Chemokine Receptor 2 (CCR2). International journal of molecular sciences 25 (16) (2024)
Bert L H Beerkens, Vasiliki Andrianopoulou, Xuesong Wang, Rongfang Liu, Gerard van Westen, Willem Jespers, Adriaan P IJzerman, Laura H Heitman, Laura H Heitman
N -Acyl- N -Alkyl Sulfonamide Probes for Ligand-Directed Covalent Labeling of GPCRs: The Adenosine A 2B Receptor as Case Study. ACS chemical biology 19 (7) (2024)
Bert L H Beerkens, Inge M Snijders, Joep Snoeck, Rongfang Liu, Anton T J Tool, Sylvia E Le Dévédec, Willem Jespers, Taco W Kuijpers, Gerard van Westen, Laura H Heitman, Adriaan P IJzerman, Laura H Heitman
Development of an Affinity-Based Probe to Profile Endogenous Human Adenosine A 3 Receptor Expression . Journal of medicinal chemistry (2023)
Bert L H Beerkens, Çağla Koç, Rongfang Liu, Bogdan I Florea, Sylvia E Le Dévédec, Laura H Heitman, Adriaan P IJzerman, Laura H Heitman
A Chemical Biological Approach to Study G Protein-Coupled Receptors: Labeling the Adenosine A 1 Receptor Using an Electrophilic Covalent Probe. ACS chemical biology 17 (11) (2022)
Bert L H Beerkens, Xuesong Wang, Maria Avgeropoulou, Lisa N Adistia, Jacobus P D van Veldhoven, Willem Jespers, Rongfang Liu, Laura H Heitman, Adriaan P IJzerman, Laura H Heitman
Development of subtype-selective covalent ligands for the adenosine A 2B receptor by tuning the reactive group. RSC medicinal chemistry 13 (7) (2022)
Tasia Amelia, Jacobus P D van Veldhoven, Matteo Falsini, Rongfang Liu, Laura H Heitman, Gerard van Westen, Elena Segala, Grégory Verdon, Robert K Y Cheng, Robert M Cooke, Daan van der Es, Adriaan P IJzerman
Crystal Structure and Subsequent Ligand Design of a Nonriboside Partial Agonist Bound to the Adenosine A2A Receptor. Journal of medicinal chemistry 64 (7) (2021)
Francesca Berni, Ermioni Kalfopoulou, Ana M Gimeno Cardells, Filippo Carboni, Laura H Heitman, Felipe Romero-Saavedra, Diana Laverde, Karmela Miklic, Suzana Malic, Tihana L Rovis, Stipan Jonjic, Sara Ali, Herman S Overkleeft, Cornelis H Hokke, Angela van Diepen, Roberto Adamo, Jiménez-Barbero Jesús, Gijsbert A van der Marel, Johannes Huebner, Jeroen D C Codée
Epitope Recognition of a Monoclonal Antibody Raised against a Synthetic Glycerol Phosphate Based Teichoic Acid. ACS chemical biology 16 (8) (2021)
Jacopo Enotarpi, Marta Tontini, Cristiana Balocchi, Laura H Heitman, Ludovic Auberger, Evita Balducci, Filippo Carboni, Daniela Proietti, Daniele Casini, Dmitri V Filippov, Hermen S Overkleeft, Gijsbert A van der Marel, Cinzia Colombo, Maria Rosaria Romano, Francesco Berti, Paolo Costantino, Jeroen D C Codée, Luigi Lay, Roberto Adamo
Publisher Correction: A stabilized glycomimetic conjugate vaccine inducing protective antibodies against Neisseria meningitidis serogroup A. Nature communications 11 (1) (2020)
Xue Yang, Laura H Heitman, Adriaan P IJzerman, Laura H Heitman
Molecular probes for the human adenosine receptors. Purinergic signalling 17 (1) (2020)
Jacopo Enotarpi, Marta Tontini, Cristiana Balocchi, Laura H Heitman, Ludovic Auberger, Evita Balducci, Filippo Carboni, Daniela Proietti, Daniele Casini, Dmitri V Filippov, Hermen S Overkleeft, Gijsbert A van der Marel, Cinzia Colombo, Maria Rosaria Romano, Francesco Berti, Paolo Costantino, Jeroen D C Codée, Luigi Lay, Roberto Adamo
A stabilized glycomimetic conjugate vaccine inducing protective antibodies against Neisseria meningitidis serogroup A. Nature communications 11 (1) (2020)
Xue Yang, Jacobus P D van Veldhoven, Jelle Offringa, Boaz J Kuiper, Eelke B Lenselink, Laura H Heitman, Laura H Heitman, Adriaan P IJzerman
Development of Covalent Ligands for G Protein-Coupled Receptors: A Case for the Human Adenosine A3 Receptor. Journal of medicinal chemistry 62 (7) (2019)
Xue Yang, Thomas J M Michiels, Coen de Jong, Marjolein Soethoudt, Niek Dekker, Euan Gordon, Mario van der Stelt, Laura H Heitman, Laura H Heitman, Adriaan P IJzerman
An Affinity-Based Probe for the Human Adenosine A2A Receptor. Journal of medicinal chemistry 61 (17) (2018)
Laura H Heitman, Francesca Berni, Wouter F J Hogendorf, Nico Meeuwenoord, Diana Laverde, Angela van Diepen, Herman S Overkleeft, Dmitri V Filippov, Cornelis H Hokke, Johannes Huebner, Gijsbert A van der Marel, Jeroen D C Codée
Streamlined Synthesis and Evaluation of Teichoic Acid Fragments. Chemistry (Weinheim an der Bergstrasse, Germany) 24 (16) (2018)