Dag Sehlin

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 28

Top Venues

Translational neurodegeneration

mAbs

Acta neuropathologica communications

Scientific reports

Uppsala Universitet Medicinska fakulteten

Uppsala Universitet Medicinska fakulteten (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Uppsala Universitet Medicinska fakulteten Feb 20 2018

Sweden

Associate professor

Uppsala Universitet Medicinska fakulteten Feb 01 2011

Sweden

Researcher

Education History

Uppsala Universitet Medicinska fakulteten Mar 29 2005 - Dec 17 2010

Sweden

PHD

Publications

María Pagnon de la Vega, Stina Syvänen, Vilmantas Giedraitis, Monique Hooley, Evangelos Konstantinidis, Silvio R Meier, Johanna Rokka, Jonas Eriksson, Ximena Aguilar, Tara L Spires-Jones, Lars Lannfelt, Lars N G Nilsson, Anna Erlandsson, Greta Hultqvist, Martin Ingelsson, Dag Sehlin
Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion. Acta neuropathologica communications 12 (1) (2024)
Eva Schlein, Ken G Andersson, Tiffany Dallas, Stina Syvanen, Dag Sehlin
Reducing neonatal Fc receptor binding enhances clearance and brain-to-blood ratio of TfR-delivered bispecific amyloid-β antibody. mAbs 16 (1) (2024)
Eva Schlein, Ken G Andersson, Tiffany Dallas, Stina Syvanen, Dag Sehlin
Reducing neonatal Fc receptor binding enhances clearance and brain-to-blood ratio of TfR-delivered bispecific amyloid-β antibody. mAbs 16 (1) (2024)
María Pagnon de la Vega, Stina Syvänen, Vilmantas Giedraitis, Monique Hooley, Evangelos Konstantinidis, Silvio R Meier, Johanna Rokka, Jonas Eriksson, Ximena Aguilar, Tara L Spires-Jones, Lars Lannfelt, Lars N G Nilsson, Anna Erlandsson, Greta Hultqvist, Martin Ingelsson, Dag Sehlin
Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion. Acta neuropathologica communications 12 (1) (2024)
Eva Schlein, Ken G Andersson, Tiffany Dallas, Stina Syvanen, Dag Sehlin
Reducing neonatal Fc receptor binding enhances clearance and brain-to-blood ratio of TfR-delivered bispecific amyloid-β antibody. mAbs 16 (1) (2024)
Eva Schlein, Ken G Andersson, Tiffany Dallas, Stina Syvanen, Dag Sehlin
Reducing neonatal Fc receptor binding enhances clearance and brain-to-blood ratio of TfR-delivered bispecific amyloid-β antibody. mAbs 16 (1) (2024)
María Pagnon de la Vega, Stina Syvänen, Vilmantas Giedraitis, Monique Hooley, Evangelos Konstantinidis, Silvio R Meier, Johanna Rokka, Jonas Eriksson, Ximena Aguilar, Tara L Spires-Jones, Lars Lannfelt, Lars N G Nilsson, Anna Erlandsson, Greta Hultqvist, Martin Ingelsson, Dag Sehlin
Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion. Acta neuropathologica communications 12 (1) (2024)
Eva Schlein, Ken G Andersson, Tiffany Dallas, Stina Syvanen, Dag Sehlin
Reducing neonatal Fc receptor binding enhances clearance and brain-to-blood ratio of TfR-delivered bispecific amyloid-β antibody. mAbs 16 (1) (2024)
Eva Schlein, Ken G Andersson, Tiffany Dallas, Stina Syvanen, Dag Sehlin
Reducing neonatal Fc receptor binding enhances clearance and brain-to-blood ratio of TfR-delivered bispecific amyloid-β antibody. mAbs 16 (1) (2024)
María Pagnon de la Vega, Stina Syvänen, Vilmantas Giedraitis, Monique Hooley, Evangelos Konstantinidis, Silvio R Meier, Johanna Rokka, Jonas Eriksson, Ximena Aguilar, Tara L Spires-Jones, Lars Lannfelt, Lars N G Nilsson, Anna Erlandsson, Greta Hultqvist, Martin Ingelsson, Dag Sehlin
Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion. Acta neuropathologica communications 12 (1) (2024)
Mara Zielinski, Fernanda S Peralta Reyes, Lothar Gremer, Sarah Schemmert, Benedikt Frieg, Luisa U Schäfer, Antje Willuweit, Lili Donner, Margitta Elvers, Lars N G Nilsson, Stina Syvanen, Dag Sehlin, Martin Ingelsson, Dieter Willbold, Gunnar F Schröder
Cryo-EM of Aβ fibrils from mouse models find tg-APP ArcSwe fibrils resemble those found in patients with sporadic Alzheimer's disease. Nature neuroscience (2023)
Gillian Bonvicini, Stina Syvänen, Ken G Andersson, Merja Haaparanta-Solin, Francisco López-Picón, Dag Sehlin
ImmunoPET imaging of amyloid-beta in a rat model of Alzheimer's disease with a bispecific, brain-penetrating fusion protein. Translational neurodegeneration 11 (1) (2022)
Gillian Bonvicini, Stina Syvänen, Ken G Andersson, Merja Haaparanta-Solin, Francisco López-Picón, Dag Sehlin
ImmunoPET imaging of amyloid-beta in a rat model of Alzheimer's disease with a bispecific, brain-penetrating fusion protein. Translational neurodegeneration 11 (1) (2022)
Gillian Bonvicini, Stina Syvänen, Ken G Andersson, Merja Haaparanta-Solin, Francisco López-Picón, Dag Sehlin
ImmunoPET imaging of amyloid-beta in a rat model of Alzheimer's disease with a bispecific, brain-penetrating fusion protein. Translational neurodegeneration 11 (1) (2022)
Gillian Bonvicini, Stina Syvänen, Ken G Andersson, Merja Haaparanta-Solin, Francisco López-Picón, Dag Sehlin
ImmunoPET imaging of amyloid-beta in a rat model of Alzheimer's disease with a bispecific, brain-penetrating fusion protein. Translational neurodegeneration 11 (1) (2022)
Gillian Bonvicini, Stina Syvänen, Ken G Andersson, Merja Haaparanta-Solin, Francisco López-Picón, Dag Sehlin
ImmunoPET imaging of amyloid-beta in a rat model of Alzheimer's disease with a bispecific, brain-penetrating fusion protein. Translational neurodegeneration 11 (1) (2022)
Sahar Roshanbin, Ulrika H Julku, Mengfei Xiong, Jonas Eriksson, Eliezer Masliah, Greta Hultqvist, Joakim Bergström, Martin Ingelsson, Stina Syvänen, Dag Sehlin
Reduction of αSYN Pathology in a Mouse Model of PD Using a Brain-Penetrating Bispecific Antibody. Pharmaceutics 14 (7) (2022)
Rebecca Faresjö, Hanna Lindberg, Stefan Ståhl, John Löfblom, Stina Syvänen, Dag Sehlin
Transferrin Receptor Binding BBB-Shuttle Facilitates Brain Delivery of Anti-Aβ-Affibodies. Pharmaceutical research 39 (7) (2022)
Sara Lopes van den Broek, Vladimir Shalgunov, Rocío García Vázquez, Natalie Beschorner, Natasha S R Bidesi, Maiken Nedergaard, Gitte Moos Knudsen, Dag Sehlin, Stina Syvänen, Matthias Manfred Herth
Pretargeted Imaging beyond the Blood-Brain Barrier-Utopia or Feasible? Pharmaceuticals (Basel, Switzerland) 15 (10) (2022)
Eva Schlein, Stina Syvanen, Johanna Rokka, Tobias Gustavsson, Raffaella Rossin, Marc S Robillard, Jonas Eriksson, Dag Sehlin
Functionalization of Radiolabeled Antibodies to Enhance Peripheral Clearance for High Contrast Brain Imaging. Molecular pharmaceutics 19 (11) (2022)
María Pagnon de la Vega, Vilmantas Giedraitis, Wojciech Michno, Lena Kilander, Gokhan Guner, Mara Zielinski, Malin Löwenmark, RoseMarie Brundin, Torsten Danfors, Linda Söderberg, Irina Alafuzoff, Lars N G Nilsson, Anna Erlandsson, Dieter Willbold, Stephan A Müller, Gunnar F Schröder, Jörg Hanrieder, Stefan F Lichtenthaler, Lars Lannfelt, Dag Sehlin, Martin Ingelsson
The Uppsala APP deletion causes early onset autosomal dominant Alzheimer's disease by altering APP processing and increasing amyloid β fibril formation. Science translational medicine 13 (606) (2021)
Silvio R Meier, Dag Sehlin, Sahar Roshanbin, Victoria Lim Falk, Takashi Saito, Takaomi C Saido, Ulf Neumann, Johanna Rokka, Jonas Eriksson, Stina Syvanen
11C-PIB and 124I-antibody PET provide differing estimates of brain amyloid-beta after therapeutic intervention. Journal of nuclear medicine : official publication, Society of Nuclear Medicine (2021)
Stina Syvanen, Xiaotian T Fang, Rebecca Faresjö, Johanna Rokka, Lars Lannfelt, Dag E Olberg, Jonas Eriksson, Dag Sehlin
Fluorine-18-Labeled Antibody Ligands for PET Imaging of Amyloid-β in Brain. ACS chemical neuroscience 11 (24) (2020)
Tobias Gustavsson, Stina Syvanen, Paul O'Callaghan, Dag Sehlin
SPECT imaging of distribution and retention of a brain-penetrating bispecific amyloid-β antibody in a mouse model of Alzheimer's disease. Translational neurodegeneration 9 (1) (2020)
Sofia Gustafsson, Dag Sehlin, Erik Lampa, Margareta Hammarlund-Udenaes, Irena Loryan
Heterogeneous drug tissue binding in brain regions of rats, Alzheimer's patients and controls: impact on translational drug development. Scientific reports 9 (1) (2019)
Stina Syvänen, Greta Hultqvist, Tobias Gustavsson, Astrid Gumucio, Hanna Laudon, Linda Söderberg, Martin Ingelsson, Lars Lannfelt, Dag Sehlin
Efficient clearance of Aβ protofibrils in AβPP-transgenic mice treated with a brain-penetrating bifunctional antibody. Alzheimer's research & therapy 10 (1) (2018)
Dag Sehlin, Xiaotian T Fang, Silvio R Meier, Malin Jansson, Stina Syvanen
Pharmacokinetics, biodistribution and brain retention of a bispecific antibody-based PET radioligand for imaging of amyloid-β. Scientific reports 7 (1) (2017)
Dag Sehlin, Xiaotian T Fang, Linda Cato, Gunnar Antoni, Lars Lannfelt, Stina Syvänen
Antibody-based PET imaging of amyloid beta in mouse models of Alzheimer's disease. Nature communications 7 (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Dag Sehlin