Lothar Gremer

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 29

Top Topics

Electron Microscopy

Molecular Dynamics Simulations

Top Venues

Journal of the American Chemical Society

Chemistry (Weinheim an der Bergstrasse, Germany)

Proceedings of the National Academy of Sciences of the United States of America

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Nina Becker, Benedikt Frieg, Lothar Gremer, Tatsiana Kupreichyk, Luis Gardon, Patrick Freiburg, Philipp Neudecker, Dieter Willbold, Holger Gohlke, Henrike Heise
Atomic Resolution Insights into pH Shift Induced Deprotonation Events in LS-Shaped Aβ(1-42) Amyloid Fibrils. Journal of the American Chemical Society 145 (4) (2023)
Nina Becker, Benedikt Frieg, Lothar Gremer, Tatsiana Kupreichyk, Luis Gardon, Patrick Freiburg, Philipp Neudecker, Dieter Willbold, Holger Gohlke, Henrike Heise
Atomic Resolution Insights into pH Shift Induced Deprotonation Events in LS-Shaped Aβ(1-42) Amyloid Fibrils. Journal of the American Chemical Society 145 (4) (2023)
Luis Gardon, Nina Becker, Lothar Gremer, Henrike Heise
Structural Impact of N-terminal Pyroglutamate in an Amyloid-β(3-42) Fibril Probed by Solid-State NMR Spectroscopy. Chemistry (Weinheim an der Bergstrasse, Germany) 30 (10) (2023)
Luis Gardon, Nina Becker, Lothar Gremer, Henrike Heise
Structural Impact of N-terminal Pyroglutamate in an Amyloid-β(3-42) Fibril Probed by Solid-State NMR Spectroscopy. Chemistry (Weinheim an der Bergstrasse, Germany) 30 (10) (2023)
Nina Becker, Benedikt Frieg, Lothar Gremer, Tatsiana Kupreichyk, Luis Gardon, Patrick Freiburg, Philipp Neudecker, Dieter Willbold, Holger Gohlke, Henrike Heise
Atomic Resolution Insights into pH Shift Induced Deprotonation Events in LS-Shaped Aβ(1-42) Amyloid Fibrils. Journal of the American Chemical Society 145 (4) (2023)
Nina Becker, Benedikt Frieg, Lothar Gremer, Tatsiana Kupreichyk, Luis Gardon, Patrick Freiburg, Philipp Neudecker, Dieter Willbold, Holger Gohlke, Henrike Heise
Atomic Resolution Insights into pH Shift Induced Deprotonation Events in LS-Shaped Aβ(1-42) Amyloid Fibrils. Journal of the American Chemical Society 145 (4) (2023)
Luis Macorano, Taniya M Binny, Tobias Spiegl, Victoria Klimenko, Anna Singer, Linda Oberleitner, Violetta M Applegate, Sarah Seyffert, Anja Stefanski, Lothar Gremer, Christoph G W Gertzen, Astrid Höppner, Sander H J Smits, Eva C M Nowack
DNA-binding and protein structure of nuclear factors likely acting in genetic information processing in the Paulinella chromatophore. Proceedings of the National Academy of Sciences of the United States of America 120 (27) (2023)
Nina Becker, Benedikt Frieg, Lothar Gremer, Tatsiana Kupreichyk, Luis Gardon, Patrick Freiburg, Philipp Neudecker, Dieter Willbold, Holger Gohlke, Henrike Heise
Atomic Resolution Insights into pH Shift Induced Deprotonation Events in LS-Shaped Aβ(1-42) Amyloid Fibrils. Journal of the American Chemical Society 145 (4) (2023)
Luis Macorano, Taniya M Binny, Tobias Spiegl, Victoria Klimenko, Anna Singer, Linda Oberleitner, Violetta M Applegate, Sarah Seyffert, Anja Stefanski, Lothar Gremer, Christoph G W Gertzen, Astrid Höppner, Sander H J Smits, Eva C M Nowack
DNA-binding and protein structure of nuclear factors likely acting in genetic information processing in the Paulinella chromatophore. Proceedings of the National Academy of Sciences of the United States of America 120 (27) (2023)
Luis Gardon, Nina Becker, Lothar Gremer, Henrike Heise
Structural Impact of N-terminal Pyroglutamylate in an Amyloid-β(3-42) Fibril Probed by Solid-State NMR Spectroscopy. Chemistry (Weinheim an der Bergstrasse, Germany) (2023)
Nina Becker, Benedikt Frieg, Lothar Gremer, Tatsiana Kupreichyk, Luis Gardon, Patrick Freiburg, Philipp Neudecker, Dieter Willbold, Holger Gohlke, Henrike Heise
Atomic Resolution Insights into pH Shift Induced Deprotonation Events in LS-Shaped Aβ(1-42) Amyloid Fibrils. Journal of the American Chemical Society 145 (4) (2023)
Mara Zielinski, Fernanda S Peralta Reyes, Lothar Gremer, Sarah Schemmert, Benedikt Frieg, Luisa U Schäfer, Antje Willuweit, Lili Donner, Margitta Elvers, Lars N G Nilsson, Stina Syvanen, Dag Sehlin, Martin Ingelsson, Dieter Willbold, Gunnar F Schröder
Cryo-EM of Aβ fibrils from mouse models find tg-APP ArcSwe fibrils resemble those found in patients with sporadic Alzheimer's disease. Nature neuroscience (2023)
Nina Becker, Benedikt Frieg, Lothar Gremer, Tatsiana Kupreichyk, Luis Gardon, Patrick Freiburg, Philipp Neudecker, Dieter Willbold, Holger Gohlke, Henrike Heise
Atomic Resolution Insights into pH Shift Induced Deprotonation Events in LS-Shaped Aβ(1-42) Amyloid Fibrils. Journal of the American Chemical Society (2023)
Luis Macorano, Taniya M Binny, Tobias Spiegl, Victoria Klimenko, Anna Singer, Linda Oberleitner, Violetta M Applegate, Sarah Seyffert, Anja Stefanski, Lothar Gremer, Christoph G W Gertzen, Astrid Höppner, Sander H J Smits, Eva C M Nowack
DNA-binding and protein structure of nuclear factors likely acting in genetic information processing in the Paulinella chromatophore. Proceedings of the National Academy of Sciences of the United States of America 120 (27) (2023)
Niloufar Mosaddeghzadeh, Silke Pudewell, Farhad Bazgir, Neda S Kazemein Jasemi, Oliver H F Krumbach, Lothar Gremer, Dieter Willbold, Radovan Dvorsky, Mohammad Reza Ahmadian
CDC42-IQGAP Interactions Scrutinized: New Insights into the Binding Properties of the GAP-Related Domain. International journal of molecular sciences 23 (16) (2022)
Debabrata Maity, Yujeong Oh, Lothar Gremer, Wolfgang Hoyer, Mazin Magzoub, Andrew D Hamilton
Cucurbit[7]uril Inhibits Islet Amyloid Polypeptide Aggregation by Targeting N Terminus Hot Segments and Attenuates Cytotoxicity. Chemistry (Weinheim an der Bergstrasse, Germany) 28 (38) (2022)
Ricarda Törner, Tatsiana Kupreichyk, Lothar Gremer, Elisa Colas Debled, Daphna Fenel, Sarah Schemmert, Pierre Gans, Dieter Willbold, Guy Schoehn, Wolfgang Hoyer, Jerome Boisbouvier
Structural basis for the inhibition of IAPP fibril formation by the co-chaperonin prefoldin. Nature communications 13 (1) (2022)
Debabrata Maity, Yujeong Oh, Lothar Gremer, Wolfgang Hoyer, Mazin Magzoub, Andrew D Hamilton
Cucurbit[7]uril Inhibits Islet Amyloid Polypeptide Aggregation by Targeting N Terminus Hot Segments and Attenuates Cytotoxicity. Chemistry (Weinheim an der Bergstrasse, Germany) 28 (38) (2022)
Neda S Kazemein Jasemi, Christian Herrmann, Eva Magdalena Estirado, Lothar Gremer, Dieter Willbold, Luc Brunsveld, Radovan Dvorsky, Mohammad Reza Ahmadian
The intramolecular allostery of GRB2 governing its interaction with SOS1 is modulated by phosphotyrosine ligands. The Biochemical journal 478 (14) (2021)
Else F van Gerresheim, Arne Herring, Lothar Gremer, Andreas Müller-Schiffmann, Kathy Keyvani, Carsten Korth
The interaction of insoluble Amyloid-β with soluble Amyloid-β dimers decreases Amyloid-β plaque numbers. Neuropathology and applied neurobiology 47 (5) (2021)
Eduard V Bocharov, Lothar Gremer, Anatoly S Urban, Ivan S Okhrimenko, Pavel E Volynsky, Kirill D Nadezhdin, Olga V Bocharova, Daniil A Kornilov, Yuliya A Zagryadskaya, Anna V Kamynina, Pavel K Kuzmichev, Janine Kutzsche, Najoua Bolakhrif, Andreas Müller-Schiffmann, Norbert A Dencher, Alexander S Arseniev, Roman G Efremov, Valentin I Gordeliy, Dieter Willbold
All-d-Enantiomeric Peptide D3 Designed for Alzheimer's Disease Treatment Dynamically Interacts with Membrane-Bound Amyloid-β Precursors. Journal of medicinal chemistry 64 (22) (2021)
Debabrata Maity, Sunil Kumar, Ruyof AlHussein, Lothar Gremer, Madeline Howarth, Laura Karpauskaite, Wolfgang Hoyer, Mazin Magzoub, Andrew D Hamilton
Sub-stoichiometric inhibition of IAPP aggregation: a peptidomimetic approach to anti-amyloid agents. RSC chemical biology 1 (4) (2020)
Christine Röder, Tatsiana Kupreichyk, Lothar Gremer, Luisa U Schäfer, Karunakar Reddy Pothula, Raimond B G Ravelli, Dieter Willbold, Wolfgang Hoyer, Gunnar F Schröder
Cryo-EM structure of islet amyloid polypeptide fibrils reveals similarities with amyloid-β fibrils. Nature structural & molecular biology 27 (7) (2020)
Nadine S Rösener, Lothar Gremer, Michael M Wördehoff, Tatsiana Kupreichyk, Manuel Etzkorn, Philipp Neudecker, Wolfgang Hoyer
Clustering of human prion protein and α-synuclein oligomers requires the prion protein N-terminus. Communications biology 3 (1) (2020)
Stefan Klinker, Sabine Stindt, Lothar Gremer, Johannes G Bode, Christoph G W Gertzen, Holger Gohlke, Oliver H Weiergräber, Silke Hoffmann, Dieter Willbold
Phosphorylated tyrosine 93 of hepatitis C virus nonstructural protein 5A is essential for interaction with host c-Src and efficient viral replication. The Journal of biological chemistry 294 (18) (2019)
Christine Röder, Nicola Vettore, Lena N Mangels, Lothar Gremer, Raimond B G Ravelli, Dieter Willbold, Wolfgang Hoyer, Alexander K Buell, Gunnar F Schröder
Atomic structure of PI3-kinase SH3 amyloid fibrils by cryo-electron microscopy. Nature communications 10 (1) (2019)
Kristiane A K Rusitzka, Leigh T Stephenson, Agnieszka Szczepaniak, Lothar Gremer, Dieter Willbold, Dieter Willbold, Baptiste Gault
A near atomic-scale view at the composition of amyloid-beta fibrils by atom probe tomography. Scientific reports 8 (1) (2018)
Filip Hasecke, Tatiana Miti, Carlos Perez, Jeremy Barton, Daniel Schölzel, Lothar Gremer, Clara S R Grüning, Garrett Matthews, Georg Meisl, Tuomas P J Knowles, Dieter Willbold, Philipp Neudecker, Henrike Heise, Ghanim Ullah, Wolfgang Hoyer, Martin Muschol
Origin of metastable oligomers and their effects on amyloid fibril self-assembly. Chemical science 9 (27) (2018)
Lothar Gremer, Daniel Schölzel, Carla Schenk, Elke Reinartz, Jörg Labahn, Raimond B G Ravelli, Markus Tusche, Carmen Lopez-Iglesias, Wolfgang Hoyer, Henrike Heise, Dieter Willbold, Gunnar F Schröder
Fibril structure of amyloid-β(1-42) by cryo-electron microscopy. Science (New York, N.Y.) 358 (6359) (2017)