Darren T Hwee

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 12

Top Topics

Hypertrophic Cardiomyopathy

Acute Respiratory Distress Syndrome

Skeletal Muscle

Inflammatory Response

Top Venues

Science translational medicine

The Journal of general physiology

The Journal of physiology

Journal of veterinary pharmacology and therapeutics

This page only lists publications with an associated author ORCID identifier.

Publications

Sandra Donkervoort, Martijn van de Locht, Dario Ronchi, Janine Reunert, Catriona A Mclean, Maha Saad Zaki, Rotem Orbach, Josine M de Winter, Stefan Conijn, Daan Hoomoedt, Osorio Lopes Abath Neto, Francesca Magri, Angela N Viaene, A Reghan Foley, Svetlana Gorokhova, Veronique Bolduc, Ying Hu, Nicole Acquaye, Laura Napoli, Julien H Park, Kalyan Immadisetty, Lee B Miles, Mona Essawi, Salar McModie, Leonardo F Ferreira, Simona Zanotti, Sarah B Neuhaus, Livija Medne, Nagham ElBagoury, Kory R Johnson, Yong Zhang, Nigel G Laing, Mark R Davis, Robert J Bryson-Richardson, Darren T Hwee, James J Hartman, Fady I Malik, Peter Michael Kekenes-Huskey, Giacomo Pietro Comi, Wessam E Sharaf-Eldin, Thorsten Marquardt, Gianina Ravenscroft, Carsten G Bonnemann, Coen A C Ottenheijm
Pathogenic TNNI1 variants disrupt sarcomere contractility resulting in hypo- and hypercontractile muscle disease. Science translational medicine 16 (741) (2024)
Ricardo A Galli Caro, Tamara C Borsboom, Charlotte Gineste, Lorenza Brocca, Maira Rossi, Darren T Hwee, Fady I Malik, Roberto Bottinelli, Julien Gondin, Maria-Antonietta Pellegrino, Josine M de Winter, Coen A C Ottenheijm
Tirasemtiv enhances submaximal muscle tension in an Acta1:p.Asp286Gly mouse model of nemaline myopathy. The Journal of general physiology 156 (4) (2024)
Ricardo A Galli Caro, Tamara C Borsboom, Charlotte Gineste, Lorenza Brocca, Maira Rossi, Darren T Hwee, Fady I Malik, Roberto Bottinelli, Julien Gondin, Maria-Antonietta Pellegrino, Josine M de Winter, Coen A C Ottenheijm
Tirasemtiv enhances submaximal muscle tension in an Acta1:p.Asp286Gly mouse model of nemaline myopathy. The Journal of general physiology 156 (4) (2024)
Sandra Donkervoort, Martijn van de Locht, Dario Ronchi, Janine Reunert, Catriona A Mclean, Maha Saad Zaki, Rotem Orbach, Josine M de Winter, Stefan Conijn, Daan Hoomoedt, Osorio Lopes Abath Neto, Francesca Magri, Angela N Viaene, A Reghan Foley, Svetlana Gorokhova, Veronique Bolduc, Ying Hu, Nicole Acquaye, Laura Napoli, Julien H Park, Kalyan Immadisetty, Lee B Miles, Mona Essawi, Salar McModie, Leonardo F Ferreira, Simona Zanotti, Sarah B Neuhaus, Livija Medne, Nagham ElBagoury, Kory R Johnson, Yong Zhang, Nigel G Laing, Mark R Davis, Robert J Bryson-Richardson, Darren T Hwee, James J Hartman, Fady I Malik, Peter Michael Kekenes-Huskey, Giacomo Pietro Comi, Wessam E Sharaf-Eldin, Thorsten Marquardt, Gianina Ravenscroft, Carsten G Bonnemann, Coen A C Ottenheijm
Pathogenic TNNI1 variants disrupt sarcomere contractility resulting in hypo- and hypercontractile muscle disease. Science translational medicine 16 (741) (2024)
Ricardo A Galli Caro, Tamara C Borsboom, Charlotte Gineste, Lorenza Brocca, Maira Rossi, Darren T Hwee, Fady I Malik, Roberto Bottinelli, Julien Gondin, Maria-Antonietta Pellegrino, Josine M de Winter, Coen A C Ottenheijm
Tirasemtiv enhances submaximal muscle tension in an Acta1:p.Asp286Gly mouse model of nemaline myopathy. The Journal of general physiology 156 (4) (2024)
Sandra Donkervoort, Martijn van de Locht, Dario Ronchi, Janine Reunert, Catriona A Mclean, Maha Saad Zaki, Rotem Orbach, Josine M de Winter, Stefan Conijn, Daan Hoomoedt, Osorio Lopes Abath Neto, Francesca Magri, Angela N Viaene, A Reghan Foley, Svetlana Gorokhova, Veronique Bolduc, Ying Hu, Nicole Acquaye, Laura Napoli, Julien H Park, Kalyan Immadisetty, Lee B Miles, Mona Essawi, Salar McModie, Leonardo F Ferreira, Simona Zanotti, Sarah B Neuhaus, Livija Medne, Nagham ElBagoury, Kory R Johnson, Yong Zhang, Nigel G Laing, Mark R Davis, Robert J Bryson-Richardson, Darren T Hwee, James J Hartman, Fady I Malik, Peter Michael Kekenes-Huskey, Giacomo Pietro Comi, Wessam E Sharaf-Eldin, Thorsten Marquardt, Gianina Ravenscroft, Carsten G Bonnemann, Coen A C Ottenheijm
Pathogenic TNNI1 variants disrupt sarcomere contractility resulting in hypo- and hypercontractile muscle disease. Science translational medicine 16 (741) (2024)
Ricardo A Galli Caro, Tamara C Borsboom, Charlotte Gineste, Lorenza Brocca, Maira Rossi, Darren T Hwee, Fady I Malik, Roberto Bottinelli, Julien Gondin, Maria-Antonietta Pellegrino, Josine M de Winter, Coen A C Ottenheijm
Tirasemtiv enhances submaximal muscle tension in an Acta1:p.Asp286Gly mouse model of nemaline myopathy. The Journal of general physiology 156 (4) (2024)
Marloes van den Berg, Zhonghua Shi, Wout J Claassen, Pleuni Hooijman, Christopher T A Lewis, Jesper Løvind Andersen, Robbert J van der Pijl, Sylvia J P Bogaards, Stefan Conijn, Eva L Peters, Leon P L Begthel, Bas A Uijterwijk, Johan Lindqvist, Paul R Langlais, Armand R J Girbes, Sandra Stapel, Henk L Granzier, Kenneth S Campbell, Weikang Ma, Thomas C Irving, Darren T Hwee, James J Hartman, Fady I Malik, Marinus Paul, Albertus Beishuizen, Julien Ochala, Leo Heunks, Coen A C Ottenheijm
Super-relaxed myosins contribute to respiratory muscle hibernation in mechanically ventilated patients. Science translational medicine 16 (758) (2024)
Marloes van den Berg, Zhonghua Shi, Wout J Claassen, Pleuni Hooijman, Christopher T A Lewis, Jesper Løvind Andersen, Robbert J van der Pijl, Sylvia J P Bogaards, Stefan Conijn, Eva L Peters, Leon P L Begthel, Bas A Uijterwijk, Johan Lindqvist, Paul R Langlais, Armand R J Girbes, Sandra Stapel, Henk L Granzier, Kenneth S Campbell, Weikang Ma, Thomas C Irving, Darren T Hwee, James J Hartman, Fady I Malik, Marinus Paul, Albertus Beishuizen, Julien Ochala, Leo Heunks, Coen A C Ottenheijm
Super-relaxed myosins contribute to respiratory muscle hibernation in mechanically ventilated patients. Science translational medicine 16 (758) (2024)
Ashley N Sharpe, Maureen S Oldach, Joanna L Kaplan, Victor Rivas, Samantha L Kovacs, Darren T Hwee, Bradley P Morgan, Fady I Malik, Samantha P Harris, Joshua A Stern
Pharmacokinetics of a single dose of Aficamten (CK-274) on cardiac contractility in a A31P MYBPC3 hypertrophic cardiomyopathy cat model. Journal of veterinary pharmacology and therapeutics (2022)
Arthur J Cheng, Darren T Hwee, Leo H Kim, Nickie Durham, Hsiao T Yang, Aaron C Hinken, Adam R Kennedy, Ronald L Terjung, Jeffrey R Jasper, Fady I Malik, Håkan Westerblad
Fast skeletal muscle troponin activator CK-2066260 increases fatigue resistance by reducing the energetic cost of muscle contraction. The Journal of physiology 597 (17) (2019)
Darren T Hwee, Arthur J Cheng, James J Hartman, Aaron C Hinken, Ken Lee, Nickie Durham, Alan J Russell, Fady I Malik, Håkan Westerblad, Jeffrey R Jasper
The Ca2+ sensitizer CK-2066260 increases myofibrillar Ca2+ sensitivity and submaximal force selectively in fast skeletal muscle. The Journal of physiology 595 (5) (2017)