Henk L Granzier (Henk Granzier)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 38

Top Topics

Duchenne Muscular Dystrophy

Skeletal Muscle

Top Venues

Acta neuropathologica

Circulation. Genomic and precision medicine

The Journal of general physiology

International journal of molecular sciences

This page only lists publications with an associated author ORCID identifier.

Publications

Esmat Karimi, Jochen Gohlke, Mila van der Borgh, Johan Lindqvist, Zaynab Hourani, Justin Kolb, Stacy Cossette, Michael W Lawlor, Coen Ottenheijm, Henk L Granzier
Characterization of NEB pathogenic variants in patients reveals novel nemaline myopathy disease mechanisms and omecamtiv mecarbil force effects. Acta neuropathologica 147 (1) (2024)
Zachery R Gregorich, Yanghai Zhang, Timothy J Kamp, Henk L Granzier, Wei Guo
Mechanisms of RBM20 Cardiomyopathy: Insights From Model Systems. Circulation. Genomic and precision medicine 17 (1) (2024)
Zachery R Gregorich, Yanghai Zhang, Timothy J Kamp, Henk L Granzier, Wei Guo
Mechanisms of RBM20 Cardiomyopathy: Insights From Model Systems. Circulation. Genomic and precision medicine (2024)
Esmat Karimi, Jochen Gohlke, Mila van der Borgh, Johan Lindqvist, Zaynab Hourani, Justin Kolb, Stacy Cossette, Michael W Lawlor, Coen Ottenheijm, Henk L Granzier
Characterization of NEB pathogenic variants in patients reveals novel nemaline myopathy disease mechanisms and omecamtiv mecarbil force effects. Acta neuropathologica 147 (1) (2024)
Esmat Karimi, Jochen Gohlke, Mila van der Borgh, Johan Lindqvist, Zaynab Hourani, Justin Kolb, Stacy Cossette, Michael W Lawlor, Coen Ottenheijm, Henk L Granzier
Characterization of NEB pathogenic variants in patients reveals novel nemaline myopathy disease mechanisms and omecamtiv mecarbil force effects. Acta neuropathologica 147 (1) (2024)
Esmat Karimi, Jochen Gohlke, Mila van der Borgh, Johan Lindqvist, Zaynab Hourani, Justin Kolb, Stacy Cossette, Michael W Lawlor, Coen Ottenheijm, Henk L Granzier
Characterization of NEB pathogenic variants in patients reveals novel nemaline myopathy disease mechanisms and omecamtiv mecarbil force effects. Acta neuropathologica 147 (1) (2024)
Esmat Karimi, Jochen Gohlke, Mila van der Borgh, Johan Lindqvist, Zaynab Hourani, Justin Kolb, Stacy Cossette, Michael W Lawlor, Coen Ottenheijm, Henk L Granzier
Characterization of NEB pathogenic variants in patients reveals novel nemaline myopathy disease mechanisms and omecamtiv mecarbil force effects. Acta neuropathologica 147 (1) (2024)
Zachery R Gregorich, Yanghai Zhang, Timothy J Kamp, Henk L Granzier, Wei Guo
Mechanisms of RBM20 Cardiomyopathy: Insights From Model Systems. Circulation. Genomic and precision medicine 17 (1) (2024)
Juliana Mira Hernandez, Erin Y Shen, Christopher Y Ko, Zaynab Hourani, Emily R Spencer, Daria Smoliarchuk, Julie Bossuyt, Henk L Granzier, Donald M Bers, Bence Hegyi
Differential sex-dependent susceptibility to diastolic dysfunction and arrhythmia in cardiomyocytes from obese diabetic HFpEF model. Cardiovascular research (2024)
Juliana Mira Hernandez, Erin Y Shen, Christopher Y Ko, Zaynab Hourani, Emily R Spencer, Daria Smoliarchuk, Julie Bossuyt, Henk L Granzier, Donald M Bers, Bence Hegyi
Differential sex-dependent susceptibility to diastolic dysfunction and arrhythmia in cardiomyocytes from obese diabetic HFpEF model. Cardiovascular research (2024)
Esmat Karimi, Jochen Gohlke, Mila van der Borgh, Johan Lindqvist, Zaynab Hourani, Justin Kolb, Stacy Cossette, Michael W Lawlor, Coen Ottenheijm, Henk L Granzier
Characterization of NEB pathogenic variants in patients reveals novel nemaline myopathy disease mechanisms and omecamtiv mecarbil force effects. Acta neuropathologica 147 (1) (2024)
Esmat Karimi, Jochen Gohlke, Mila van der Borgh, Johan Lindqvist, Zaynab Hourani, Justin Kolb, Stacy Cossette, Michael W Lawlor, Coen Ottenheijm, Henk L Granzier
Characterization of NEB pathogenic variants in patients reveals novel nemaline myopathy disease mechanisms and omecamtiv mecarbil force effects. Acta neuropathologica 147 (1) (2024)
Zachery R Gregorich, Yanghai Zhang, Timothy J Kamp, Henk L Granzier, Wei Guo
Mechanisms of RBM20 Cardiomyopathy: Insights From Model Systems. Circulation. Genomic and precision medicine 17 (1) (2024)
Zachery R Gregorich, Yanghai Zhang, Timothy J Kamp, Henk L Granzier, Wei Guo
Mechanisms of RBM20 Cardiomyopathy: Insights From Model Systems. Circulation. Genomic and precision medicine (2024)
Zachery R Gregorich, Yanghai Zhang, Timothy J Kamp, Henk L Granzier, Wei Guo
Mechanisms of RBM20 Cardiomyopathy: Insights From Model Systems. Circulation. Genomic and precision medicine (2024)
Esmat Karimi, Jochen Gohlke, Mila van der Borgh, Johan Lindqvist, Zaynab Hourani, Justin Kolb, Stacy Cossette, Michael W Lawlor, Coen Ottenheijm, Henk L Granzier
Characterization of NEB pathogenic variants in patients reveals novel nemaline myopathy disease mechanisms and omecamtiv mecarbil force effects. Acta neuropathologica 147 (1) (2024)
Juliana Mira Hernandez, Erin Y Shen, Christopher Y Ko, Zaynab Hourani, Emily R Spencer, Daria Smoliarchuk, Julie Bossuyt, Henk L Granzier, Donald M Bers, Bence Hegyi
Differential sex-dependent susceptibility to diastolic dysfunction and arrhythmia in cardiomyocytes from obese diabetic HFpEF model. Cardiovascular research (2024)
Marloes van den Berg, Zhonghua Shi, Wout J Claassen, Pleuni Hooijman, Christopher T A Lewis, Jesper Løvind Andersen, Robbert J van der Pijl, Sylvia J P Bogaards, Stefan Conijn, Eva L Peters, Leon P L Begthel, Bas A Uijterwijk, Johan Lindqvist, Paul R Langlais, Armand R J Girbes, Sandra Stapel, Henk L Granzier, Kenneth S Campbell, Weikang Ma, Thomas C Irving, Darren T Hwee, James J Hartman, Fady I Malik, Marinus Paul, Albertus Beishuizen, Julien Ochala, Leo Heunks, Coen A C Ottenheijm
Super-relaxed myosins contribute to respiratory muscle hibernation in mechanically ventilated patients. Science translational medicine 16 (758) (2024)
Marloes van den Berg, Zhonghua Shi, Wout J Claassen, Pleuni Hooijman, Christopher T A Lewis, Jesper Løvind Andersen, Robbert J van der Pijl, Sylvia J P Bogaards, Stefan Conijn, Eva L Peters, Leon P L Begthel, Bas A Uijterwijk, Johan Lindqvist, Paul R Langlais, Armand R J Girbes, Sandra Stapel, Henk L Granzier, Kenneth S Campbell, Weikang Ma, Thomas C Irving, Darren T Hwee, James J Hartman, Fady I Malik, Marinus Paul, Albertus Beishuizen, Julien Ochala, Leo Heunks, Coen A C Ottenheijm
Super-relaxed myosins contribute to respiratory muscle hibernation in mechanically ventilated patients. Science translational medicine 16 (758) (2024)
David Y Barefield, Paola Tonino, Kathleen C Woulfe, Sheema Rahmanseresht, Thomas S O'Leary, Hope V Burnham, J Andrew Wasserstrom, Jonathan A Kirk, Michael J Previs, Henk L Granzier, Elizabeth M McNally
Myosin-binding protein H-like regulates myosin-binding protein distribution and function in atrial cardiomyocytes. Proceedings of the National Academy of Sciences of the United States of America 120 (51) (2023)
Johan Lindqvist, Justin Kolb, Josine de Winter, Paola Tonino, Zaynab Hourani, Siegfried Labeit, Coen Ottenheijm, Henk L Granzier
Removal of MuRF1 Increases Muscle Mass in Nemaline Myopathy Models, but Does Not Provide Functional Benefits. International journal of molecular sciences 23 (15) (2022)
Pabodha Hettige, Dhruv Mishra, Henk L Granzier, Kiisa C Nishikawa, Matthew J Gage
Contributions of Titin and Collagen to Passive Stress in Muscles from mdm Mice with a Small Deletion in Titin's Molecular Spring. International journal of molecular sciences 23 (16) (2022)
Christine R Cremo, Richard L Moss, Henk L Granzier
Further progress in understanding of myofibrillar function in health and disease. The Journal of general physiology 153 (7) (2021)
Dalma Kellermayer, Bálint Kiss, Hedvig Tordai, Attila Oláh, Henk L Granzier, Béla Merkely, Miklós Kellermayer, Tamás Radovits
Increased Expression of N2BA Titin Corresponds to More Compliant Myofibrils in Athlete's Heart. International journal of molecular sciences 22 (20) (2021)
Robbert J van der Pijl, Marloes van den Berg, Martijn van de Locht, Shengyi Shen, Sylvia J P Bogaards, Stefan Conijn, Paul R Langlais, Pleuni E Hooijman, Siegfried Labeit, Leo M A Heunks, Henk L Granzier, Coen A C Ottenheijm
Muscle ankyrin repeat protein 1 (MARP1) locks titin to the sarcomeric thin filament and is a passive force regulator. The Journal of general physiology 153 (7) (2021)
Aurélien Perrin, Corinne Metay, Marcello Villanova, Robert-Yves Carlier, Elena Pegoraro, Raul Juntas Morales, Tanya Stojkovic, Isabelle Richard, Pascale Richard, Norma B Romero, Henk L Granzier, Michel Koenig, Edoardo Malfatti, Mireille Cossee
A new congenital multicore titinopathy associated with fast myosin heavy chain deficiency. Annals of clinical and translational neurology 7 (5) (2020)
Johan Lindqvist, Weikang Ma, Frank Li, Yaeren Hernandez, Justin Kolb, Balazs Kiss, Paola Tonino, Robbert van der Pijl, Esmat Karimi, Henry Gong, Josh Strom, Zaynab Hourani, John Edward Smith, Coen Ottenheijm, Thomas Irving, Henk L Granzier
Triggering typical nemaline myopathy with compound heterozygous nebulin mutations reveals myofilament structural changes as pathomechanism. Nature communications 11 (1) (2020)
Ying Ann Chiao, Huiliang Zhang, Mariya Sweetwyne, Jeremy Whitson, Ying Sonia Ting, Nathan Basisty, Lindsay K Pino, Ellen Quarles, Ngoc-Han Nguyen, Matthew D Campbell, Tong Zhang, Matthew J Gaffrey, Gennifer Merrihew, Lu Wang, Yongping Yue, Dongsheng Duan, Henk L Granzier, Hazel H Szeto, Wei-Jun Qian, David Marcinek, Michael J MacCoss, Peter S Rabinovitch
Late-life restoration of mitochondrial function reverses cardiac dysfunction in old mice. eLife 9 (2020)
Balázs Kiss, Jochen Gohlke, Paola Tonino, Zaynab Hourani, Justin Kolb, Joshua G Strom, Olga Alekhina, John Edward Smith, Coen Ottenheijm, Carol C Gregorio, Henk L Granzier
Nebulin and Lmod2 are critical for specifying thin-filament length in skeletal muscle. Science advances 6 (46) (2020)
Frank Li, Justin Kolb, Julie Crudele, Paola Tonino, Zaynab Hourani, John E Smith, Jeffrey S Chamberlain, Henk L Granzier
Expressing a Z-disk nebulin fragment in nebulin-deficient mouse muscle: effects on muscle structure and function. Skeletal muscle 10 (1) (2020)
Henk L Granzier, Richard L Moss
Progress on the regulation of myofibrillar function: Part 2. The Journal of general physiology 151 (5) (2019)
Johan Lindqvist, Eun-Jeong Lee, Esmat Karimi, Justin Kolb, Henk L Granzier
Omecamtiv mecarbil lowers the contractile deficit in a mouse model of nebulin-based nemaline myopathy. PloS one 14 (11) (2019)
Eun-Jeong Lee, Justin Kolb, Darren T Hwee, Fady I Malik, Henk L Granzier
Functional Characterization of the Intact Diaphragm in a Nebulin-Based Nemaline Myopathy (NM) Model-Effects of the Fast Skeletal Muscle Troponin Activator tirasemtiv. International journal of molecular sciences 20 (20) (2019)
Dalma Kellermayer, John E Smith, Henk L Granzier
Titin mutations and muscle disease. Pflugers Archiv : European journal of physiology 471 (5) (2019)
Srboljub M Mijailovich, Boban Stojanovic, Djordje Nedic, Marina Svicevic, Michael A Geeves, Thomas C Irving, Henk L Granzier
Nebulin and titin modulate cross-bridge cycling and length-dependent calcium sensitivity. The Journal of general physiology 151 (5) (2019)
Rebecca E Slater, Joshua G Strom, Mei Methawasin, Martin Liss, Michael Gotthardt, Nancy K Sweitzer, Henk L Granzier
Metformin improves diastolic function in an HFpEF-like mouse model by increasing titin compliance. The Journal of general physiology 151 (1) (2018)
King-Lun Li, Mei Methawasin, Bertrand C W Tanner, Henk L Granzier, R John Solaro, Wen-Ji Dong
Sarcomere length-dependent effects on Ca2+-troponin regulation in myocardium expressing compliant titin. The Journal of general physiology 151 (1) (2018)
Ambjorn Brynnel, Yaeren Hernandez, Balazs Kiss, Johan Lindqvist, Maya Adler, Justin Kolb, Robbert van der Pijl, Jochen Gohlke, Joshua Strom, John Smith, Coen Ottenheijm, Henk L Granzier
Downsizing the molecular spring of the giant protein titin reveals that skeletal muscle titin determines passive stiffness and drives longitudinal hypertrophy. eLife 7 (2018)