David Wildes

ORCID

Publication Activity (10 Years)

Years Active: 2024-2024
Publications (10 Years): 32

Top Venues

Nature

Cancer discovery

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Álvaro Curiel-García, A Cole Edwards, Yingyun Wang, Bianca Lee, Margo Orlen, Sha Tian, Clint A Stalnecker, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Stephen A Sastra, Carmine F Palermo, Marie C Hasselluhn, Amanda R Decker-Farrell, Stephanie Chang, Lingyan Jiang, Xing Wei, Yu C Yang, Ciara Helland, Haley Courtney, Yevgeniy Gindin, Karl Muonio, Ruiping Zhao, Samantha B Kemp, Cynthia Clendenin, Rina Sor, William P Vostrejs, Priya S Hibshman, Amber M Amparo, Connor Hennessey, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Jens Brodbeck, Lorenzo Tomassoni, Basil Bakir, Nicholas D Socci, Laura E Herring, Natalie K Barker, Junning Wang, James M Cleary, Brian M Wolpin, John A Chabot, Michael D Kluger, Gulam A Manji, Kenneth Y Tsai, Miroslav Sekulic, Stephen M Lagana, Andrea Califano, Elsa Quintana, Zhengping Wang, Jacqueline A M Smith, Matthew Holderfield, David Wildes, Scott W Lowe, Michael A Badgley, Andrew J Aguirre, Robert A Anders, Ben Z Stanger, Timour Baslan, Channing J Der, Mallika Singh, Kenneth P Olive
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature 629 (8013) (2024)
Matthew Holderfield, Bianca J Lee, Jingjing Jiang, Aidan Tomlinson, Kyle J Seamon, Alessia Mira, Enrico Patrucco, Grace Goodhart, Julien Dilly, Yevgeniy Gindin, Nuntana Dinglasan, Yingyun Wang, Lick Pui Lai, Shurui Cai, Lingyan Jiang, Nicole Nasholm, Nataliya Shifrin, Cristina Blaj, Harshit Shah, James W Evans, Nilufar Montazer, Oliver Lai, Jade Shi, Ethan Ahler, Elsa Quintana, Stephanie Chang, Anthony Salvador, Abby Marquez, Jim Cregg, Yang Liu, Anthony Milin, Anqi Chen, Tamar Bar Ziv, Dylan Parsons, John E Knox, Jennifer E Klomp, Jennifer A Roth, Matthew G Rees, Melissa A Ronan, Antonio Cuevas-Navarro, Feng Hu, Piro Lito, David Santamaria, Andrew J Aguirre, Andrew M Waters, Channing J Der, Chiara Ambrogio, Zhengping Wang, Adrian L Gill, Elena S Koltun, Jacqueline A M Smith, David Wildes, Mallika Singh
Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy. Nature (2024)
Jingjing Jiang, Lingyan Jiang, Benjamin J Maldonato, Yingyun Wang, Matthew Holderfield, Ida Aronchik, Ian P Winters, Zeena Salman, Cristina Blaj, Marie Menard, Jens Brodbeck, Zhe Chen, Xing Wei, Michael J Rosen, Yevgeniy Gindin, Bianca J Lee, James W Evans, Stephanie Chang, Zhican Wang, Kyle J Seamon, Dylan Parsons, James Cregg, Abby Marquez, Aidan C A Tomlinson, Jason K Yano, John E Knox, Elsa Quintana, Andrew J Aguirre, Kathryn C Arbour, Abby Reed, W Clay Gustafson, Adrian L Gill, Elena S Koltun, David Wildes, Jacqueline A M Smith, Zhengping Wang, Mallika Singh
Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers. Cancer discovery 14 (6) (2024)
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Álvaro Curiel-García, A Cole Edwards, Yingyun Wang, Bianca Lee, Margo Orlen, Sha Tian, Clint A Stalnecker, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Stephen A Sastra, Carmine F Palermo, Marie C Hasselluhn, Amanda R Decker-Farrell, Stephanie Chang, Lingyan Jiang, Xing Wei, Yu C Yang, Ciara Helland, Haley Courtney, Yevgeniy Gindin, Karl Muonio, Ruiping Zhao, Samantha B Kemp, Cynthia Clendenin, Rina Sor, William P Vostrejs, Priya S Hibshman, Amber M Amparo, Connor Hennessey, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Jens Brodbeck, Lorenzo Tomassoni, Basil Bakir, Nicholas D Socci, Laura E Herring, Natalie K Barker, Junning Wang, James M Cleary, Brian M Wolpin, John A Chabot, Michael D Kluger, Gulam A Manji, Kenneth Y Tsai, Miroslav Sekulic, Stephen M Lagana, Andrea Califano, Elsa Quintana, Zhengping Wang, Jacqueline A M Smith, Matthew Holderfield, David Wildes, Scott W Lowe, Michael A Badgley, Andrew J Aguirre, Robert A Anders, Ben Z Stanger, Timour Baslan, Channing J Der, Mallika Singh, Kenneth P Olive
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature 629 (8013) (2024)
Jingjing Jiang, Lingyan Jiang, Benjamin J Maldonato, Yingyun Wang, Matthew Holderfield, Ida Aronchik, Ian P Winters, Zeena Salman, Cristina Blaj, Marie Menard, Jens Brodbeck, Zhe Chen, Xing Wei, Michael J Rosen, Yevgeniy Gindin, Bianca J Lee, James W Evans, Stephanie Chang, Zhican Wang, Kyle J Seamon, Dylan Parsons, James Cregg, Abby Marquez, Aidan C A Tomlinson, Jason K Yano, John E Knox, Elsa Quintana, Andrew J Aguirre, Kathryn C Arbour, Abby Reed, W Clay Gustafson, Adrian L Gill, Elena S Koltun, David Wildes, Jacqueline A M Smith, Zhengping Wang, Mallika Singh
Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers. Cancer discovery 14 (6) (2024)
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Álvaro Curiel-García, A Cole Edwards, Yingyun Wang, Bianca Lee, Margo Orlen, Sha Tian, Clint A Stalnecker, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Stephen A Sastra, Carmine F Palermo, Marie C Hasselluhn, Amanda R Decker-Farrell, Stephanie Chang, Lingyan Jiang, Xing Wei, Yu C Yang, Ciara Helland, Haley Courtney, Yevgeniy Gindin, Karl Muonio, Ruiping Zhao, Samantha B Kemp, Cynthia Clendenin, Rina Sor, William P Vostrejs, Priya S Hibshman, Amber M Amparo, Connor Hennessey, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Jens Brodbeck, Lorenzo Tomassoni, Basil Bakir, Nicholas D Socci, Laura E Herring, Natalie K Barker, Junning Wang, James M Cleary, Brian M Wolpin, John A Chabot, Michael D Kluger, Gulam A Manji, Kenneth Y Tsai, Miroslav Sekulic, Stephen M Lagana, Andrea Califano, Elsa Quintana, Zhengping Wang, Jacqueline A M Smith, Matthew Holderfield, David Wildes, Scott W Lowe, Michael A Badgley, Andrew J Aguirre, Robert A Anders, Ben Z Stanger, Timour Baslan, Channing J Der, Mallika Singh, Kenneth P Olive
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature 629 (8013) (2024)
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Álvaro Curiel-García, A Cole Edwards, Yingyun Wang, Bianca Lee, Margo Orlen, Sha Tian, Clint A Stalnecker, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Stephen A Sastra, Carmine F Palermo, Marie C Hasselluhn, Amanda R Decker-Farrell, Stephanie Chang, Lingyan Jiang, Xing Wei, Yu C Yang, Ciara Helland, Haley Courtney, Yevgeniy Gindin, Karl Muonio, Ruiping Zhao, Samantha B Kemp, Cynthia Clendenin, Rina Sor, William P Vostrejs, Priya S Hibshman, Amber M Amparo, Connor Hennessey, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Jens Brodbeck, Lorenzo Tomassoni, Basil Bakir, Nicholas D Socci, Laura E Herring, Natalie K Barker, Junning Wang, James M Cleary, Brian M Wolpin, John A Chabot, Michael D Kluger, Gulam A Manji, Kenneth Y Tsai, Miroslav Sekulic, Stephen M Lagana, Andrea Califano, Elsa Quintana, Zhengping Wang, Jacqueline A M Smith, Matthew Holderfield, David Wildes, Scott W Lowe, Michael A Badgley, Andrew J Aguirre, Robert A Anders, Ben Z Stanger, Timour Baslan, Channing J Der, Mallika Singh, Kenneth P Olive
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature 629 (8013) (2024)
Hidenori Kitai, Philip H Choi, Yu Chi Yang, Jacob A Boyer, Adele Whaley, Priya Pancholi, Claire Thant, Jason Reiter, Kevin Chen, Vladimir Markov, Hirokazu Taniguchi, Rui Yamaguchi, Hiromichi Ebi, James Evans, Jingjing Jiang, Bianca Lee, David Wildes, Elisa de Stanchina, Jacqueline A M Smith, Mallika Singh, Neal X Rosen
Combined inhibition of KRAS G12C and mTORC1 kinase is synergistic in non-small cell lung cancer. Nature communications 15 (1) (2024)
Jingjing Jiang, Lingyan Jiang, Benjamin J Maldonato, Yingyun Wang, Matthew Holderfield, Ida Aronchik, Ian P Winters, Zeena Salman, Cristina Blaj, Marie Menard, Jens Brodbeck, Zhe Chen, Xing Wei, Michael J Rosen, Yevgeniy Gindin, Bianca J Lee, James W Evans, Stephanie Chang, Zhican Wang, Kyle J Seamon, Dylan Parsons, James Cregg, Abby Marquez, Aidan C A Tomlinson, Jason K Yano, John E Knox, Elsa Quintana, Andrew J Aguirre, Kathryn C Arbour, Abby Reed, W Clay Gustafson, Adrian L Gill, Elena S Koltun, David Wildes, Jacqueline A M Smith, Zhengping Wang, Mallika Singh
Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers. Cancer discovery 14 (6) (2024)
Hidenori Kitai, Philip H Choi, Yu Chi Yang, Jacob A Boyer, Adele Whaley, Priya Pancholi, Claire Thant, Jason Reiter, Kevin Chen, Vladimir Markov, Hirokazu Taniguchi, Rui Yamaguchi, Hiromichi Ebi, James Evans, Jingjing Jiang, Bianca Lee, David Wildes, Elisa de Stanchina, Jacqueline A M Smith, Mallika Singh, Neal X Rosen
Combined inhibition of KRAS G12C and mTORC1 kinase is synergistic in non-small cell lung cancer. Nature communications 15 (1) (2024)
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Álvaro Curiel-García, A Cole Edwards, Yingyun Wang, Bianca Lee, Margo Orlen, Sha Tian, Clint A Stalnecker, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Stephen A Sastra, Carmine F Palermo, Marie C Hasselluhn, Amanda R Decker-Farrell, Stephanie Chang, Lingyan Jiang, Xing Wei, Yu C Yang, Ciara Helland, Haley Courtney, Yevgeniy Gindin, Karl Muonio, Ruiping Zhao, Samantha B Kemp, Cynthia Clendenin, Rina Sor, William P Vostrejs, Priya S Hibshman, Amber M Amparo, Connor Hennessey, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Jens Brodbeck, Lorenzo Tomassoni, Basil Bakir, Nicholas D Socci, Laura E Herring, Natalie K Barker, Junning Wang, James M Cleary, Brian M Wolpin, John A Chabot, Michael D Kluger, Gulam A Manji, Kenneth Y Tsai, Miroslav Sekulic, Stephen M Lagana, Andrea Califano, Elsa Quintana, Zhengping Wang, Jacqueline A M Smith, Matthew Holderfield, David Wildes, Scott W Lowe, Michael A Badgley, Andrew J Aguirre, Robert A Anders, Ben Z Stanger, Timour Baslan, Channing J Der, Mallika Singh, Kenneth P Olive
Tumor-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature (2024)
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Álvaro Curiel-García, A Cole Edwards, Yingyun Wang, Bianca Lee, Margo Orlen, Sha Tian, Clint A Stalnecker, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Stephen A Sastra, Carmine F Palermo, Marie C Hasselluhn, Amanda R Decker-Farrell, Stephanie Chang, Lingyan Jiang, Xing Wei, Yu C Yang, Ciara Helland, Haley Courtney, Yevgeniy Gindin, Karl Muonio, Ruiping Zhao, Samantha B Kemp, Cynthia Clendenin, Rina Sor, William P Vostrejs, Priya S Hibshman, Amber M Amparo, Connor Hennessey, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Jens Brodbeck, Lorenzo Tomassoni, Basil Bakir, Nicholas D Socci, Laura E Herring, Natalie K Barker, Junning Wang, James M Cleary, Brian M Wolpin, John A Chabot, Michael D Kluger, Gulam A Manji, Kenneth Y Tsai, Miroslav Sekulic, Stephen M Lagana, Andrea Califano, Elsa Quintana, Zhengping Wang, Jacqueline A M Smith, Matthew Holderfield, David Wildes, Scott W Lowe, Michael A Badgley, Andrew J Aguirre, Robert A Anders, Ben Z Stanger, Timour Baslan, Channing J Der, Mallika Singh, Kenneth P Olive
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature 629 (8013) (2024)
Matthew Holderfield, Bianca J Lee, Jingjing Jiang, Aidan Tomlinson, Kyle J Seamon, Alessia Mira, Enrico Patrucco, Grace Goodhart, Julien Dilly, Yevgeniy Gindin, Nuntana Dinglasan, Yingyun Wang, Lick Pui Lai, Shurui Cai, Lingyan Jiang, Nicole Nasholm, Nataliya Shifrin, Cristina Blaj, Harshit Shah, James W Evans, Nilufar Montazer, Oliver Lai, Jade Shi, Ethan Ahler, Elsa Quintana, Stephanie Chang, Anthony Salvador, Abby Marquez, Jim Cregg, Yang Liu, Anthony Milin, Anqi Chen, Tamar Bar Ziv, Dylan Parsons, John E Knox, Jennifer E Klomp, Jennifer A Roth, Matthew G Rees, Melissa A Ronan, Antonio Cuevas-Navarro, Feng Hu, Piro Lito, David Santamaria, Andrew J Aguirre, Andrew M Waters, Channing J Der, Chiara Ambrogio, Zhengping Wang, Adrian L Gill, Elena S Koltun, Jacqueline A M Smith, David Wildes, Mallika Singh
Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy. Nature (2024)
Matthew Holderfield, Bianca J Lee, Jingjing Jiang, Aidan Tomlinson, Kyle J Seamon, Alessia Mira, Enrico Patrucco, Grace Goodhart, Julien Dilly, Yevgeniy Gindin, Nuntana Dinglasan, Yingyun Wang, Lick Pui Lai, Shurui Cai, Lingyan Jiang, Nicole Nasholm, Nataliya Shifrin, Cristina Blaj, Harshit Shah, James W Evans, Nilufar Montazer, Oliver Lai, Jade Shi, Ethan Ahler, Elsa Quintana, Stephanie Chang, Anthony Salvador, Abby Marquez, Jim Cregg, Yang Liu, Anthony Milin, Anqi Chen, Tamar Bar Ziv, Dylan Parsons, John E Knox, Jennifer E Klomp, Jennifer A Roth, Matthew G Rees, Melissa A Ronan, Antonio Cuevas-Navarro, Feng Hu, Piro Lito, David Santamaria, Andrew J Aguirre, Andrew M Waters, Channing J Der, Chiara Ambrogio, Zhengping Wang, Adrian L Gill, Elena S Koltun, Jacqueline A M Smith, David Wildes, Mallika Singh
Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy. Nature (2024)
Matthew Holderfield, Bianca J Lee, Jingjing Jiang, Aidan Tomlinson, Kyle J Seamon, Alessia Mira, Enrico Patrucco, Grace Goodhart, Julien Dilly, Yevgeniy Gindin, Nuntana Dinglasan, Yingyun Wang, Lick Pui Lai, Shurui Cai, Lingyan Jiang, Nicole Nasholm, Nataliya Shifrin, Cristina Blaj, Harshit Shah, James W Evans, Nilufar Montazer, Oliver Lai, Jade Shi, Ethan Ahler, Elsa Quintana, Stephanie Chang, Anthony Salvador, Abby Marquez, Jim Cregg, Yang Liu, Anthony Milin, Anqi Chen, Tamar Bar Ziv, Dylan Parsons, John E Knox, Jennifer E Klomp, Jennifer A Roth, Matthew G Rees, Melissa A Ronan, Antonio Cuevas-Navarro, Feng Hu, Piro Lito, David Santamaria, Andrew J Aguirre, Andrew M Waters, Channing J Der, Chiara Ambrogio, Zhengping Wang, Adrian L Gill, Elena S Koltun, Jacqueline A M Smith, David Wildes, Mallika Singh
Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy. Nature 629 (8013) (2024)
Jingjing Jiang, Lingyan Jiang, Benjamin J Maldonato, Yingyun Wang, Matthew Holderfield, Ida Aronchik, Ian P Winters, Zeena Salman, Cristina Blaj, Marie Menard, Jens Brodbeck, Zhe Chen, Xing Wei, Michael J Rosen, Yevgeniy Gindin, Bianca J Lee, James W Evans, Stephanie Chang, Zhican Wang, Kyle J Seamon, Dylan Parsons, James Cregg, Abby Marquez, Aidan C A Tomlinson, Jason K Yano, John E Knox, Elsa Quintana, Andrew J Aguirre, Kathryn C Arbour, Abby Reed, W Clay Gustafson, Adrian L Gill, Elena S Koltun, David Wildes, Jacqueline A M Smith, Zhengping Wang, Mallika Singh
Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers. Cancer discovery 14 (6) (2024)
Hidenori Kitai, Philip H Choi, Yu Chi Yang, Jacob A Boyer, Adele Whaley, Priya Pancholi, Claire Thant, Jason Reiter, Kevin Chen, Vladimir Markov, Hirokazu Taniguchi, Rui Yamaguchi, Hiromichi Ebi, James Evans, Jingjing Jiang, Bianca Lee, David Wildes, Elisa de Stanchina, Jacqueline A M Smith, Mallika Singh, Neal X Rosen
Combined inhibition of KRAS G12C and mTORC1 kinase is synergistic in non-small cell lung cancer. Nature communications 15 (1) (2024)
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Álvaro Curiel-García, A Cole Edwards, Yingyun Wang, Bianca Lee, Margo Orlen, Sha Tian, Clint A Stalnecker, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Stephen A Sastra, Carmine F Palermo, Marie C Hasselluhn, Amanda R Decker-Farrell, Stephanie Chang, Lingyan Jiang, Xing Wei, Yu C Yang, Ciara Helland, Haley Courtney, Yevgeniy Gindin, Karl Muonio, Ruiping Zhao, Samantha B Kemp, Cynthia Clendenin, Rina Sor, William P Vostrejs, Priya S Hibshman, Amber M Amparo, Connor Hennessey, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Jens Brodbeck, Lorenzo Tomassoni, Basil Bakir, Nicholas D Socci, Laura E Herring, Natalie K Barker, Junning Wang, James M Cleary, Brian M Wolpin, John A Chabot, Michael D Kluger, Gulam A Manji, Kenneth Y Tsai, Miroslav Sekulic, Stephen M Lagana, Andrea Califano, Elsa Quintana, Zhengping Wang, Jacqueline A M Smith, Matthew Holderfield, David Wildes, Scott W Lowe, Michael A Badgley, Andrew J Aguirre, Robert A Anders, Ben Z Stanger, Timour Baslan, Channing J Der, Mallika Singh, Kenneth P Olive
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature 629 (8013) (2024)
Jingjing Jiang, Lingyan Jiang, Benjamin J Maldonato, Yingyun Wang, Matthew Holderfield, Ida Aronchik, Ian P Winters, Zeena Salman, Cristina Blaj, Marie Menard, Jens Brodbeck, Zhe Chen, Xing Wei, Michael J Rosen, Yevgeniy Gindin, Bianca J Lee, James W Evans, Stephanie Chang, Zhican Wang, Kyle J Seamon, Dylan Parsons, James Cregg, Abby Marquez, Aidan C A Tomlinson, Jason K Yano, John E Knox, Elsa Quintana, Andrew J Aguirre, Kathryn C Arbour, Abby Reed, W Clay Gustafson, Adrian L Gill, Elena S Koltun, David Wildes, Jacqueline A M Smith, Zhengping Wang, Mallika Singh
Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers. Cancer discovery 14 (6) (2024)
Matthew Holderfield, Bianca J Lee, Jingjing Jiang, Aidan Tomlinson, Kyle J Seamon, Alessia Mira, Enrico Patrucco, Grace Goodhart, Julien Dilly, Yevgeniy Gindin, Nuntana Dinglasan, Yingyun Wang, Lick Pui Lai, Shurui Cai, Lingyan Jiang, Nicole Nasholm, Nataliya Shifrin, Cristina Blaj, Harshit Shah, James W Evans, Nilufar Montazer, Oliver Lai, Jade Shi, Ethan Ahler, Elsa Quintana, Stephanie Chang, Anthony Salvador, Abby Marquez, Jim Cregg, Yang Liu, Anthony Milin, Anqi Chen, Tamar Bar Ziv, Dylan Parsons, John E Knox, Jennifer E Klomp, Jennifer A Roth, Matthew G Rees, Melissa A Ronan, Antonio Cuevas-Navarro, Feng Hu, Piro Lito, David Santamaria, Andrew J Aguirre, Andrew M Waters, Channing J Der, Chiara Ambrogio, Zhengping Wang, Adrian L Gill, Elena S Koltun, Jacqueline A M Smith, David Wildes, Mallika Singh
Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy. Nature 629 (8013) (2024)
Matthew Holderfield, Bianca J Lee, Jingjing Jiang, Aidan Tomlinson, Kyle J Seamon, Alessia Mira, Enrico Patrucco, Grace Goodhart, Julien Dilly, Yevgeniy Gindin, Nuntana Dinglasan, Yingyun Wang, Lick Pui Lai, Shurui Cai, Lingyan Jiang, Nicole Nasholm, Nataliya Shifrin, Cristina Blaj, Harshit Shah, James W Evans, Nilufar Montazer, Oliver Lai, Jade Shi, Ethan Ahler, Elsa Quintana, Stephanie Chang, Anthony Salvador, Abby Marquez, Jim Cregg, Yang Liu, Anthony Milin, Anqi Chen, Tamar Bar Ziv, Dylan Parsons, John E Knox, Jennifer E Klomp, Jennifer A Roth, Matthew G Rees, Melissa A Ronan, Antonio Cuevas-Navarro, Feng Hu, Piro Lito, David Santamaria, Andrew J Aguirre, Andrew M Waters, Channing J Der, Chiara Ambrogio, Zhengping Wang, Adrian L Gill, Elena S Koltun, Jacqueline A M Smith, David Wildes, Mallika Singh
Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy. Nature (2024)
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Álvaro Curiel-García, A Cole Edwards, Yingyun Wang, Bianca Lee, Margo Orlen, Sha Tian, Clint A Stalnecker, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Stephen A Sastra, Carmine F Palermo, Marie C Hasselluhn, Amanda R Decker-Farrell, Stephanie Chang, Lingyan Jiang, Xing Wei, Yu C Yang, Ciara Helland, Haley Courtney, Yevgeniy Gindin, Karl Muonio, Ruiping Zhao, Samantha B Kemp, Cynthia Clendenin, Rina Sor, William P Vostrejs, Priya S Hibshman, Amber M Amparo, Connor Hennessey, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Jens Brodbeck, Lorenzo Tomassoni, Basil Bakir, Nicholas D Socci, Laura E Herring, Natalie K Barker, Junning Wang, James M Cleary, Brian M Wolpin, John A Chabot, Michael D Kluger, Gulam A Manji, Kenneth Y Tsai, Miroslav Sekulic, Stephen M Lagana, Andrea Califano, Elsa Quintana, Zhengping Wang, Jacqueline A M Smith, Matthew Holderfield, David Wildes, Scott W Lowe, Michael A Badgley, Andrew J Aguirre, Robert A Anders, Ben Z Stanger, Timour Baslan, Channing J Der, Mallika Singh, Kenneth P Olive
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature 629 (8013) (2024)
Jingjing Jiang, Lingyan Jiang, Benjamin J Maldonato, Yingyun Wang, Matthew Holderfield, Ida Aronchik, Ian P Winters, Zeena Salman, Cristina Blaj, Marie Menard, Jens Brodbeck, Zhe Chen, Xing Wei, Michael J Rosen, Yevgeniy Gindin, Bianca J Lee, James W Evans, Stephanie Chang, Zhican Wang, Kyle J Seamon, Dylan Parsons, James Cregg, Abby Marquez, Aidan C A Tomlinson, Jason K Yano, John E Knox, Elsa Quintana, Andrew J Aguirre, Kathryn C Arbour, Abby Reed, W Clay Gustafson, Adrian L Gill, Elena S Koltun, David Wildes, Jacqueline A M Smith, Zhengping Wang, Mallika Singh
Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers. Cancer discovery (2024)
Matthew Holderfield, Bianca J Lee, Jingjing Jiang, Aidan Tomlinson, Kyle J Seamon, Alessia Mira, Enrico Patrucco, Grace Goodhart, Julien Dilly, Yevgeniy Gindin, Nuntana Dinglasan, Yingyun Wang, Lick Pui Lai, Shurui Cai, Lingyan Jiang, Nicole Nasholm, Nataliya Shifrin, Cristina Blaj, Harshit Shah, James W Evans, Nilufar Montazer, Oliver Lai, Jade Shi, Ethan Ahler, Elsa Quintana, Stephanie Chang, Anthony Salvador, Abby Marquez, Jim Cregg, Yang Liu, Anthony Milin, Anqi Chen, Tamar Bar Ziv, Dylan Parsons, John E Knox, Jennifer E Klomp, Jennifer A Roth, Matthew G Rees, Melissa A Ronan, Antonio Cuevas-Navarro, Feng Hu, Piro Lito, David Santamaria, Andrew J Aguirre, Andrew M Waters, Channing J Der, Chiara Ambrogio, Zhengping Wang, Adrian L Gill, Elena S Koltun, Jacqueline A M Smith, David Wildes, Mallika Singh
Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy. Nature (2024)
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Álvaro Curiel-García, A Cole Edwards, Yingyun Wang, Bianca Lee, Margo Orlen, Sha Tian, Clint A Stalnecker, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Stephen A Sastra, Carmine F Palermo, Marie C Hasselluhn, Amanda R Decker-Farrell, Stephanie Chang, Lingyan Jiang, Xing Wei, Yu C Yang, Ciara Helland, Haley Courtney, Yevgeniy Gindin, Karl Muonio, Ruiping Zhao, Samantha B Kemp, Cynthia Clendenin, Rina Sor, William P Vostrejs, Priya S Hibshman, Amber M Amparo, Connor Hennessey, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Jens Brodbeck, Lorenzo Tomassoni, Basil Bakir, Nicholas D Socci, Laura E Herring, Natalie K Barker, Junning Wang, James M Cleary, Brian M Wolpin, John A Chabot, Michael D Kluger, Gulam A Manji, Kenneth Y Tsai, Miroslav Sekulic, Stephen M Lagana, Andrea Califano, Elsa Quintana, Zhengping Wang, Jacqueline A M Smith, Matthew Holderfield, David Wildes, Scott W Lowe, Michael A Badgley, Andrew J Aguirre, Robert A Anders, Ben Z Stanger, Timour Baslan, Channing J Der, Mallika Singh, Kenneth P Olive
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature (2024)
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Álvaro Curiel-García, A Cole Edwards, Yingyun Wang, Bianca Lee, Margo Orlen, Sha Tian, Clint A Stalnecker, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Stephen A Sastra, Carmine F Palermo, Marie C Hasselluhn, Amanda R Decker-Farrell, Stephanie Chang, Lingyan Jiang, Xing Wei, Yu C Yang, Ciara Helland, Haley Courtney, Yevgeniy Gindin, Karl Muonio, Ruiping Zhao, Samantha B Kemp, Cynthia Clendenin, Rina Sor, William P Vostrejs, Priya S Hibshman, Amber M Amparo, Connor Hennessey, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Jens Brodbeck, Lorenzo Tomassoni, Basil Bakir, Nicholas D Socci, Laura E Herring, Natalie K Barker, Junning Wang, James M Cleary, Brian M Wolpin, John A Chabot, Michael D Kluger, Gulam A Manji, Kenneth Y Tsai, Miroslav Sekulic, Stephen M Lagana, Andrea Califano, Elsa Quintana, Zhengping Wang, Jacqueline A M Smith, Matthew Holderfield, David Wildes, Scott W Lowe, Michael A Badgley, Andrew J Aguirre, Robert A Anders, Ben Z Stanger, Timour Baslan, Channing J Der, Mallika Singh, Kenneth P Olive
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature 629 (8013) (2024)
Matthew Holderfield, Bianca J Lee, Jingjing Jiang, Aidan Tomlinson, Kyle J Seamon, Alessia Mira, Enrico Patrucco, Grace Goodhart, Julien Dilly, Yevgeniy Gindin, Nuntana Dinglasan, Yingyun Wang, Lick Pui Lai, Shurui Cai, Lingyan Jiang, Nicole Nasholm, Nataliya Shifrin, Cristina Blaj, Harshit Shah, James W Evans, Nilufar Montazer, Oliver Lai, Jade Shi, Ethan Ahler, Elsa Quintana, Stephanie Chang, Anthony Salvador, Abby Marquez, Jim Cregg, Yang Liu, Anthony Milin, Anqi Chen, Tamar Bar Ziv, Dylan Parsons, John E Knox, Jennifer E Klomp, Jennifer A Roth, Matthew G Rees, Melissa A Ronan, Antonio Cuevas-Navarro, Feng Hu, Piro Lito, David Santamaria, Andrew J Aguirre, Andrew M Waters, Channing J Der, Chiara Ambrogio, Zhengping Wang, Adrian L Gill, Elena S Koltun, Jacqueline A M Smith, David Wildes, Mallika Singh
Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy. Nature 629 (8013) (2024)
Matthew Holderfield, Bianca J Lee, Jingjing Jiang, Aidan Tomlinson, Kyle J Seamon, Alessia Mira, Enrico Patrucco, Grace Goodhart, Julien Dilly, Yevgeniy Gindin, Nuntana Dinglasan, Yingyun Wang, Lick Pui Lai, Shurui Cai, Lingyan Jiang, Nicole Nasholm, Nataliya Shifrin, Cristina Blaj, Harshit Shah, James W Evans, Nilufar Montazer, Oliver Lai, Jade Shi, Ethan Ahler, Elsa Quintana, Stephanie Chang, Anthony Salvador, Abby Marquez, Jim Cregg, Yang Liu, Anthony Milin, Anqi Chen, Tamar Bar Ziv, Dylan Parsons, John E Knox, Jennifer E Klomp, Jennifer A Roth, Matthew G Rees, Melissa A Ronan, Antonio Cuevas-Navarro, Feng Hu, Piro Lito, David Santamaria, Andrew J Aguirre, Andrew M Waters, Channing J Der, Chiara Ambrogio, Zhengping Wang, Adrian L Gill, Elena S Koltun, Jacqueline A M Smith, David Wildes, Mallika Singh
Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy. Nature 629 (8013) (2024)
Matthew Holderfield, Bianca J Lee, Jingjing Jiang, Aidan Tomlinson, Kyle J Seamon, Alessia Mira, Enrico Patrucco, Grace Goodhart, Julien Dilly, Yevgeniy Gindin, Nuntana Dinglasan, Yingyun Wang, Lick Pui Lai, Shurui Cai, Lingyan Jiang, Nicole Nasholm, Nataliya Shifrin, Cristina Blaj, Harshit Shah, James W Evans, Nilufar Montazer, Oliver Lai, Jade Shi, Ethan Ahler, Elsa Quintana, Stephanie Chang, Anthony Salvador, Abby Marquez, Jim Cregg, Yang Liu, Anthony Milin, Anqi Chen, Tamar Bar Ziv, Dylan Parsons, John E Knox, Jennifer E Klomp, Jennifer A Roth, Matthew G Rees, Melissa A Ronan, Antonio Cuevas-Navarro, Feng Hu, Piro Lito, David Santamaria, Andrew J Aguirre, Andrew M Waters, Channing J Der, Chiara Ambrogio, Zhengping Wang, Adrian L Gill, Elena S Koltun, Jacqueline A M Smith, David Wildes, Mallika Singh
Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy. Nature 629 (8013) (2024)
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Álvaro Curiel-García, A Cole Edwards, Yingyun Wang, Bianca Lee, Margo Orlen, Sha Tian, Clint A Stalnecker, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Stephen A Sastra, Carmine F Palermo, Marie C Hasselluhn, Amanda R Decker-Farrell, Stephanie Chang, Lingyan Jiang, Xing Wei, Yu C Yang, Ciara Helland, Haley Courtney, Yevgeniy Gindin, Karl Muonio, Ruiping Zhao, Samantha B Kemp, Cynthia Clendenin, Rina Sor, William P Vostrejs, Priya S Hibshman, Amber M Amparo, Connor Hennessey, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Jens Brodbeck, Lorenzo Tomassoni, Basil Bakir, Nicholas D Socci, Laura E Herring, Natalie K Barker, Junning Wang, James M Cleary, Brian M Wolpin, John A Chabot, Michael D Kluger, Gulam A Manji, Kenneth Y Tsai, Miroslav Sekulic, Stephen M Lagana, Andrea Califano, Elsa Quintana, Zhengping Wang, Jacqueline A M Smith, Matthew Holderfield, David Wildes, Scott W Lowe, Michael A Badgley, Andrew J Aguirre, Robert A Anders, Ben Z Stanger, Timour Baslan, Channing J Der, Mallika Singh, Kenneth P Olive
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature 629 (8013) (2024)
Hidenori Kitai, Philip H Choi, Yu Chi Yang, Jacob A Boyer, Adele Whaley, Priya Pancholi, Claire Thant, Jason Reiter, Kevin Chen, Vladimir Markov, Hirokazu Taniguchi, Rui Yamaguchi, Hiromichi Ebi, James Evans, Jingjing Jiang, Bianca Lee, David Wildes, Elisa de Stanchina, Jacqueline A M Smith, Mallika Singh, Neal X Rosen
Combined inhibition of KRAS G12C and mTORC1 kinase is synergistic in non-small cell lung cancer. Nature communications 15 (1) (2024)
Matthew Holderfield, Bianca J Lee, Jingjing Jiang, Aidan Tomlinson, Kyle J Seamon, Alessia Mira, Enrico Patrucco, Grace Goodhart, Julien Dilly, Yevgeniy Gindin, Nuntana Dinglasan, Yingyun Wang, Lick Pui Lai, Shurui Cai, Lingyan Jiang, Nicole Nasholm, Nataliya Shifrin, Cristina Blaj, Harshit Shah, James W Evans, Nilufar Montazer, Oliver Lai, Jade Shi, Ethan Ahler, Elsa Quintana, Stephanie Chang, Anthony Salvador, Abby Marquez, Jim Cregg, Yang Liu, Anthony Milin, Anqi Chen, Tamar Bar Ziv, Dylan Parsons, John E Knox, Jennifer E Klomp, Jennifer A Roth, Matthew G Rees, Melissa A Ronan, Antonio Cuevas-Navarro, Feng Hu, Piro Lito, David Santamaria, Andrew J Aguirre, Andrew M Waters, Channing J Der, Chiara Ambrogio, Zhengping Wang, Adrian L Gill, Elena S Koltun, Jacqueline A M Smith, David Wildes, Mallika Singh
Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy. Nature 629 (8013) (2024)

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David Wildes