Scott W Lowe

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 66

Top Venues

Nature

Nature cancer

Cancer discovery

Science (New York, N.Y.)

This page only lists publications with an associated author ORCID identifier.

Publications

Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Álvaro Curiel-García, A Cole Edwards, Yingyun Wang, Bianca Lee, Margo Orlen, Sha Tian, Clint A Stalnecker, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Stephen A Sastra, Carmine F Palermo, Marie C Hasselluhn, Amanda R Decker-Farrell, Stephanie Chang, Lingyan Jiang, Xing Wei, Yu C Yang, Ciara Helland, Haley Courtney, Yevgeniy Gindin, Karl Muonio, Ruiping Zhao, Samantha B Kemp, Cynthia Clendenin, Rina Sor, William P Vostrejs, Priya S Hibshman, Amber M Amparo, Connor Hennessey, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Jens Brodbeck, Lorenzo Tomassoni, Basil Bakir, Nicholas D Socci, Laura E Herring, Natalie K Barker, Junning Wang, James M Cleary, Brian M Wolpin, John A Chabot, Michael D Kluger, Gulam A Manji, Kenneth Y Tsai, Miroslav Sekulic, Stephen M Lagana, Andrea Califano, Elsa Quintana, Zhengping Wang, Jacqueline A M Smith, Matthew Holderfield, David Wildes, Scott W Lowe, Michael A Badgley, Andrew J Aguirre, Robert A Anders, Ben Z Stanger, Timour Baslan, Channing J Der, Mallika Singh, Kenneth P Olive
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature 629 (8013) (2024)
Julien Dilly, Megan T Hoffman, Laleh Abbassi, Ziyue Li, Francesca Paradiso, Brendan D Parent, Connor J Hennessey, Alexander C Jordan, Micaela Morgado, Shatavisha Dasgupta, Giselle A Uribe, Annan Yang, Kevin S Kapner, Felix P Hambitzer, Li Qiang, Hanrong Feng, Jacob Geisberg, Junning Wang, Kyle E Evans, Hengyu Lu, Aislyn Schalck, Ningping Feng, Anastasia M Lopez, Christopher A Bristow, Michael P Kim, Kimal I Rajapakshe, Vahid Bahrambeigi, Jennifer A Roth, Kavita Garg, Paola A Guerrero, Ben Z Stanger, Simona Cristea, Scott W Lowe, Timour Baslan, Eliezer Van Allen, Joseph D Mancias, Emily Chan, Abraham Anderson, Yuliya V Katlinskaya, Alex K Shalek, David S Hong, Shubham Pant, Jill Hallin, Kenna Anderes, Peter Olson, Timothy P Heffernan, Seema Chugh, James G Christensen, Anirban Maitra, Brian M Wolpin, Srivatsan Raghavan, Jonathan Andrew Nowak, Peter S Winter, Stephanie K Dougan, Andrew J Aguirre
Mechanisms of resistance to oncogenic KRAS inhibition in pancreatic cancer. Cancer discovery (2024)
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Álvaro Curiel-García, A Cole Edwards, Yingyun Wang, Bianca Lee, Margo Orlen, Sha Tian, Clint A Stalnecker, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Stephen A Sastra, Carmine F Palermo, Marie C Hasselluhn, Amanda R Decker-Farrell, Stephanie Chang, Lingyan Jiang, Xing Wei, Yu C Yang, Ciara Helland, Haley Courtney, Yevgeniy Gindin, Karl Muonio, Ruiping Zhao, Samantha B Kemp, Cynthia Clendenin, Rina Sor, William P Vostrejs, Priya S Hibshman, Amber M Amparo, Connor Hennessey, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Jens Brodbeck, Lorenzo Tomassoni, Basil Bakir, Nicholas D Socci, Laura E Herring, Natalie K Barker, Junning Wang, James M Cleary, Brian M Wolpin, John A Chabot, Michael D Kluger, Gulam A Manji, Kenneth Y Tsai, Miroslav Sekulic, Stephen M Lagana, Andrea Califano, Elsa Quintana, Zhengping Wang, Jacqueline A M Smith, Matthew Holderfield, David Wildes, Scott W Lowe, Michael A Badgley, Andrew J Aguirre, Robert A Anders, Ben Z Stanger, Timour Baslan, Channing J Der, Mallika Singh, Kenneth P Olive
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature 629 (8013) (2024)
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Álvaro Curiel-García, A Cole Edwards, Yingyun Wang, Bianca Lee, Margo Orlen, Sha Tian, Clint A Stalnecker, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Stephen A Sastra, Carmine F Palermo, Marie C Hasselluhn, Amanda R Decker-Farrell, Stephanie Chang, Lingyan Jiang, Xing Wei, Yu C Yang, Ciara Helland, Haley Courtney, Yevgeniy Gindin, Karl Muonio, Ruiping Zhao, Samantha B Kemp, Cynthia Clendenin, Rina Sor, William P Vostrejs, Priya S Hibshman, Amber M Amparo, Connor Hennessey, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Jens Brodbeck, Lorenzo Tomassoni, Basil Bakir, Nicholas D Socci, Laura E Herring, Natalie K Barker, Junning Wang, James M Cleary, Brian M Wolpin, John A Chabot, Michael D Kluger, Gulam A Manji, Kenneth Y Tsai, Miroslav Sekulic, Stephen M Lagana, Andrea Califano, Elsa Quintana, Zhengping Wang, Jacqueline A M Smith, Matthew Holderfield, David Wildes, Scott W Lowe, Michael A Badgley, Andrew J Aguirre, Robert A Anders, Ben Z Stanger, Timour Baslan, Channing J Der, Mallika Singh, Kenneth P Olive
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature 629 (8013) (2024)
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Álvaro Curiel-García, A Cole Edwards, Yingyun Wang, Bianca Lee, Margo Orlen, Sha Tian, Clint A Stalnecker, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Stephen A Sastra, Carmine F Palermo, Marie C Hasselluhn, Amanda R Decker-Farrell, Stephanie Chang, Lingyan Jiang, Xing Wei, Yu C Yang, Ciara Helland, Haley Courtney, Yevgeniy Gindin, Karl Muonio, Ruiping Zhao, Samantha B Kemp, Cynthia Clendenin, Rina Sor, William P Vostrejs, Priya S Hibshman, Amber M Amparo, Connor Hennessey, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Jens Brodbeck, Lorenzo Tomassoni, Basil Bakir, Nicholas D Socci, Laura E Herring, Natalie K Barker, Junning Wang, James M Cleary, Brian M Wolpin, John A Chabot, Michael D Kluger, Gulam A Manji, Kenneth Y Tsai, Miroslav Sekulic, Stephen M Lagana, Andrea Califano, Elsa Quintana, Zhengping Wang, Jacqueline A M Smith, Matthew Holderfield, David Wildes, Scott W Lowe, Michael A Badgley, Andrew J Aguirre, Robert A Anders, Ben Z Stanger, Timour Baslan, Channing J Der, Mallika Singh, Kenneth P Olive
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature 629 (8013) (2024)
Josef Leibold, Kaloyan M Tsanov, Corina Amor, Yu-Jui Ho, Francisco J Sánchez Rivera, Judith Feucht, Timour Baslan, Hsuan-An Chen, Sha Tian, Janelle Simon, Alexandra Wuest, John E Wilkinson, Scott W Lowe
Somatic mouse models of gastric cancer reveal genotype-specific features of metastatic disease. Nature cancer 5 (2) (2024)
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Álvaro Curiel-García, A Cole Edwards, Yingyun Wang, Bianca Lee, Margo Orlen, Sha Tian, Clint A Stalnecker, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Stephen A Sastra, Carmine F Palermo, Marie C Hasselluhn, Amanda R Decker-Farrell, Stephanie Chang, Lingyan Jiang, Xing Wei, Yu C Yang, Ciara Helland, Haley Courtney, Yevgeniy Gindin, Karl Muonio, Ruiping Zhao, Samantha B Kemp, Cynthia Clendenin, Rina Sor, William P Vostrejs, Priya S Hibshman, Amber M Amparo, Connor Hennessey, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Jens Brodbeck, Lorenzo Tomassoni, Basil Bakir, Nicholas D Socci, Laura E Herring, Natalie K Barker, Junning Wang, James M Cleary, Brian M Wolpin, John A Chabot, Michael D Kluger, Gulam A Manji, Kenneth Y Tsai, Miroslav Sekulic, Stephen M Lagana, Andrea Califano, Elsa Quintana, Zhengping Wang, Jacqueline A M Smith, Matthew Holderfield, David Wildes, Scott W Lowe, Michael A Badgley, Andrew J Aguirre, Robert A Anders, Ben Z Stanger, Timour Baslan, Channing J Der, Mallika Singh, Kenneth P Olive
Tumor-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature (2024)
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Álvaro Curiel-García, A Cole Edwards, Yingyun Wang, Bianca Lee, Margo Orlen, Sha Tian, Clint A Stalnecker, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Stephen A Sastra, Carmine F Palermo, Marie C Hasselluhn, Amanda R Decker-Farrell, Stephanie Chang, Lingyan Jiang, Xing Wei, Yu C Yang, Ciara Helland, Haley Courtney, Yevgeniy Gindin, Karl Muonio, Ruiping Zhao, Samantha B Kemp, Cynthia Clendenin, Rina Sor, William P Vostrejs, Priya S Hibshman, Amber M Amparo, Connor Hennessey, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Jens Brodbeck, Lorenzo Tomassoni, Basil Bakir, Nicholas D Socci, Laura E Herring, Natalie K Barker, Junning Wang, James M Cleary, Brian M Wolpin, John A Chabot, Michael D Kluger, Gulam A Manji, Kenneth Y Tsai, Miroslav Sekulic, Stephen M Lagana, Andrea Califano, Elsa Quintana, Zhengping Wang, Jacqueline A M Smith, Matthew Holderfield, David Wildes, Scott W Lowe, Michael A Badgley, Andrew J Aguirre, Robert A Anders, Ben Z Stanger, Timour Baslan, Channing J Der, Mallika Singh, Kenneth P Olive
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature 629 (8013) (2024)
Corina Amor, Judith Feucht, Josef Leibold, Yu-Jui Ho, Changyu Zhu, Direna Alonso-Curbelo, Jorge Mansilla-Soto, Jacob A Boyer, Xiang Li, Theodoros Giavridis, Amanda Kulick, Shauna Houlihan, Ellinor Peerschke, Scott L Friedman, Vladimir Ponomarev, Alessandra Piersigilli, Michel Sadelain, Scott W Lowe
Author Correction: Senolytic CAR T cells reverse senescence-associated pathologies. Nature (2024)
Josef Leibold, Kaloyan M Tsanov, Corina Amor, Yu-Jui Ho, Francisco J Sánchez Rivera, Judith Feucht, Timour Baslan, Hsuan-An Chen, Sha Tian, Janelle Simon, Alexandra Wuest, John E Wilkinson, Scott W Lowe
Somatic mouse models of gastric cancer reveal genotype-specific features of metastatic disease. Nature cancer (2024)
Josef Leibold, Kaloyan M Tsanov, Corina Amor, Yu-Jui Ho, Francisco J Sánchez Rivera, Judith Feucht, Timour Baslan, Hsuan-An Chen, Sha Tian, Janelle Simon, Alexandra Wuest, John E Wilkinson, Scott W Lowe
Somatic mouse models of gastric cancer reveal genotype-specific features of metastatic disease. Nature cancer 5 (2) (2024)
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Álvaro Curiel-García, A Cole Edwards, Yingyun Wang, Bianca Lee, Margo Orlen, Sha Tian, Clint A Stalnecker, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Stephen A Sastra, Carmine F Palermo, Marie C Hasselluhn, Amanda R Decker-Farrell, Stephanie Chang, Lingyan Jiang, Xing Wei, Yu C Yang, Ciara Helland, Haley Courtney, Yevgeniy Gindin, Karl Muonio, Ruiping Zhao, Samantha B Kemp, Cynthia Clendenin, Rina Sor, William P Vostrejs, Priya S Hibshman, Amber M Amparo, Connor Hennessey, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Jens Brodbeck, Lorenzo Tomassoni, Basil Bakir, Nicholas D Socci, Laura E Herring, Natalie K Barker, Junning Wang, James M Cleary, Brian M Wolpin, John A Chabot, Michael D Kluger, Gulam A Manji, Kenneth Y Tsai, Miroslav Sekulic, Stephen M Lagana, Andrea Califano, Elsa Quintana, Zhengping Wang, Jacqueline A M Smith, Matthew Holderfield, David Wildes, Scott W Lowe, Michael A Badgley, Andrew J Aguirre, Robert A Anders, Ben Z Stanger, Timour Baslan, Channing J Der, Mallika Singh, Kenneth P Olive
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature 629 (8013) (2024)
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Álvaro Curiel-García, A Cole Edwards, Yingyun Wang, Bianca Lee, Margo Orlen, Sha Tian, Clint A Stalnecker, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Stephen A Sastra, Carmine F Palermo, Marie C Hasselluhn, Amanda R Decker-Farrell, Stephanie Chang, Lingyan Jiang, Xing Wei, Yu C Yang, Ciara Helland, Haley Courtney, Yevgeniy Gindin, Karl Muonio, Ruiping Zhao, Samantha B Kemp, Cynthia Clendenin, Rina Sor, William P Vostrejs, Priya S Hibshman, Amber M Amparo, Connor Hennessey, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Jens Brodbeck, Lorenzo Tomassoni, Basil Bakir, Nicholas D Socci, Laura E Herring, Natalie K Barker, Junning Wang, James M Cleary, Brian M Wolpin, John A Chabot, Michael D Kluger, Gulam A Manji, Kenneth Y Tsai, Miroslav Sekulic, Stephen M Lagana, Andrea Califano, Elsa Quintana, Zhengping Wang, Jacqueline A M Smith, Matthew Holderfield, David Wildes, Scott W Lowe, Michael A Badgley, Andrew J Aguirre, Robert A Anders, Ben Z Stanger, Timour Baslan, Channing J Der, Mallika Singh, Kenneth P Olive
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature 629 (8013) (2024)
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Álvaro Curiel-García, A Cole Edwards, Yingyun Wang, Bianca Lee, Margo Orlen, Sha Tian, Clint A Stalnecker, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Stephen A Sastra, Carmine F Palermo, Marie C Hasselluhn, Amanda R Decker-Farrell, Stephanie Chang, Lingyan Jiang, Xing Wei, Yu C Yang, Ciara Helland, Haley Courtney, Yevgeniy Gindin, Karl Muonio, Ruiping Zhao, Samantha B Kemp, Cynthia Clendenin, Rina Sor, William P Vostrejs, Priya S Hibshman, Amber M Amparo, Connor Hennessey, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Jens Brodbeck, Lorenzo Tomassoni, Basil Bakir, Nicholas D Socci, Laura E Herring, Natalie K Barker, Junning Wang, James M Cleary, Brian M Wolpin, John A Chabot, Michael D Kluger, Gulam A Manji, Kenneth Y Tsai, Miroslav Sekulic, Stephen M Lagana, Andrea Califano, Elsa Quintana, Zhengping Wang, Jacqueline A M Smith, Matthew Holderfield, David Wildes, Scott W Lowe, Michael A Badgley, Andrew J Aguirre, Robert A Anders, Ben Z Stanger, Timour Baslan, Channing J Der, Mallika Singh, Kenneth P Olive
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature (2024)
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Álvaro Curiel-García, A Cole Edwards, Yingyun Wang, Bianca Lee, Margo Orlen, Sha Tian, Clint A Stalnecker, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Stephen A Sastra, Carmine F Palermo, Marie C Hasselluhn, Amanda R Decker-Farrell, Stephanie Chang, Lingyan Jiang, Xing Wei, Yu C Yang, Ciara Helland, Haley Courtney, Yevgeniy Gindin, Karl Muonio, Ruiping Zhao, Samantha B Kemp, Cynthia Clendenin, Rina Sor, William P Vostrejs, Priya S Hibshman, Amber M Amparo, Connor Hennessey, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Jens Brodbeck, Lorenzo Tomassoni, Basil Bakir, Nicholas D Socci, Laura E Herring, Natalie K Barker, Junning Wang, James M Cleary, Brian M Wolpin, John A Chabot, Michael D Kluger, Gulam A Manji, Kenneth Y Tsai, Miroslav Sekulic, Stephen M Lagana, Andrea Califano, Elsa Quintana, Zhengping Wang, Jacqueline A M Smith, Matthew Holderfield, David Wildes, Scott W Lowe, Michael A Badgley, Andrew J Aguirre, Robert A Anders, Ben Z Stanger, Timour Baslan, Channing J Der, Mallika Singh, Kenneth P Olive
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature 629 (8013) (2024)
Josef Leibold, Kaloyan M Tsanov, Corina Amor, Yu-Jui Ho, Francisco J Sánchez Rivera, Judith Feucht, Timour Baslan, Hsuan-An Chen, Sha Tian, Janelle Simon, Alexandra Wuest, John E Wilkinson, Scott W Lowe
Somatic mouse models of gastric cancer reveal genotype-specific features of metastatic disease. Nature cancer 5 (2) (2024)
Josef Leibold, Kaloyan M Tsanov, Corina Amor, Yu-Jui Ho, Francisco J Sánchez Rivera, Judith Feucht, Timour Baslan, Hsuan-An Chen, Sha Tian, Janelle Simon, Alexandra Wuest, John E Wilkinson, Scott W Lowe
Somatic mouse models of gastric cancer reveal genotype-specific features of metastatic disease. Nature cancer (2024)
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Álvaro Curiel-García, A Cole Edwards, Yingyun Wang, Bianca Lee, Margo Orlen, Sha Tian, Clint A Stalnecker, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Stephen A Sastra, Carmine F Palermo, Marie C Hasselluhn, Amanda R Decker-Farrell, Stephanie Chang, Lingyan Jiang, Xing Wei, Yu C Yang, Ciara Helland, Haley Courtney, Yevgeniy Gindin, Karl Muonio, Ruiping Zhao, Samantha B Kemp, Cynthia Clendenin, Rina Sor, William P Vostrejs, Priya S Hibshman, Amber M Amparo, Connor Hennessey, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Jens Brodbeck, Lorenzo Tomassoni, Basil Bakir, Nicholas D Socci, Laura E Herring, Natalie K Barker, Junning Wang, James M Cleary, Brian M Wolpin, John A Chabot, Michael D Kluger, Gulam A Manji, Kenneth Y Tsai, Miroslav Sekulic, Stephen M Lagana, Andrea Califano, Elsa Quintana, Zhengping Wang, Jacqueline A M Smith, Matthew Holderfield, David Wildes, Scott W Lowe, Michael A Badgley, Andrew J Aguirre, Robert A Anders, Ben Z Stanger, Timour Baslan, Channing J Der, Mallika Singh, Kenneth P Olive
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature 629 (8013) (2024)
Josef Leibold, Kaloyan M Tsanov, Corina Amor, Yu-Jui Ho, Francisco J Sánchez Rivera, Judith Feucht, Timour Baslan, Hsuan-An Chen, Sha Tian, Janelle Simon, Alexandra Wuest, John E Wilkinson, Scott W Lowe
Somatic mouse models of gastric cancer reveal genotype-specific features of metastatic disease. Nature cancer 5 (2) (2024)
Changyu Zhu, Yadira M Soto-Feliciano, John P Morris, Chun-Hao Huang, Richard P Koche, Yu-Jui Ho, Ana Banito, Chun-Wei David Chen, Aditya Shroff, Sha Tian, Geulah Livshits, Chi-Chao Chen, Myles Fennell, Scott A Armstrong, C David Allis, Darjus F Tschaharganeh, Scott W Lowe
MLL3 regulates the CDKN2A tumor suppressor locus in liver cancer. eLife 12 (2023)
Alyna Katti, Adrián Vega-Pérez, Miguel Foronda, Jill Zimmerman, Maria Paz Zafra, Elizabeth Granowsky, Sukanya Goswami, Eric E Gardner, Bianca J Diaz, Janelle M Simon, Alexandra Wuest, Wei Luan, Maria Teresa Calvo Fernandez, Anastasia P Kadina, John A Walker, Kevin Holden, Scott W Lowe, Francisco J Sánchez Rivera, Lukas E Dow
Generation of precision preclinical cancer models using regulated in vivo base editing. Nature biotechnology (2023)
Cassandra Burdziak, Direna Alonso-Curbelo, Thomas Walle, José Reyes, Francisco M Barriga, Doron Haviv, Yubin Xie, Zhen Zhao, Chujun Julia Zhao, Hsuan-An Chen, Ojasvi Chaudhary, Ignas Masilionis, Zi-Ning Choo, Vianne Gao, Wei Luan, Alexandra Wuest, Yu-Jui Ho, Yuhong Wei, Abdel Razaq Ahmad A Alyasin, Richard P Koche, Linas Mazutis, Ronan Chaligné, Tal Nawy, Scott W Lowe, Dana Pe'er
Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis. Science (New York, N.Y.) 380 (6645) (2023)
Jing Hu, Francisco J Sánchez Rivera, Zhenghan Wang, Gabriela N Johnson, Yu-Jui Ho, Karuna Ganesh, Shigeaki Umeda, Siting Gan, Adriana M Mujal, Rebecca B Delconte, Jessica P Hampton, Huiyong Zhao, Sanjay Kottapalli, Elisa de Stanchina, Christine A Iacobuzio-Donahue, Dana Pe'er, Scott W Lowe, Joseph C Sun, Joan Massagué
STING inhibits the reactivation of dormant metastasis in lung adenocarcinoma. Nature (2023)
Loretah Chibaya, Katherine C Murphy, Kelly D DeMarco, Sneha Gopalan, Haibo Liu, Chaitanya N Parikh, Yvette Lopez-Diaz, Melissa Faulkner, Junhui Li, John P Morris, Yu-Jui Ho, Sachliv K Chana, Janelle Simon, Wei Luan, Amanda Kulick, Elisa de Stanchina, Karl Simin, Julie Lihua Zhu, Thomas G Fazzio, Scott W Lowe, Marcus Ruscetti
EZH2 inhibition remodels the inflammatory senescence-associated secretory phenotype to potentiate pancreatic cancer immune surveillance. Nature cancer (2023)
Cassandra Burdziak, Direna Alonso-Curbelo, Thomas Walle, José Reyes, Francisco M Barriga, Doron Haviv, Yubin Xie, Zhen Zhao, Chujun Julia Zhao, Hsuan-An Chen, Ojasvi Chaudhary, Ignas Masilionis, Zi-Ning Choo, Vianne Gao, Wei Luan, Alexandra Wuest, Yu-Jui Ho, Yuhong Wei, Abdel Razaq Ahmad A Alyasin, Richard P Koche, Linas Mazutis, Ronan Chaligné, Tal Nawy, Scott W Lowe, Dana Pe'er
Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis. Science (New York, N.Y.) 380 (6645) (2023)
Loretah Chibaya, Katherine C Murphy, Kelly D DeMarco, Sneha Gopalan, Haibo Liu, Chaitanya N Parikh, Yvette Lopez-Diaz, Melissa Faulkner, Junhui Li, John P Morris, Yu-Jui Ho, Sachliv K Chana, Janelle Simon, Wei Luan, Amanda Kulick, Elisa de Stanchina, Karl Simin, Julie Lihua Zhu, Thomas G Fazzio, Scott W Lowe, Marcus Ruscetti
EZH2 inhibition remodels the inflammatory senescence-associated secretory phenotype to potentiate pancreatic cancer immune surveillance. Nature cancer (2023)
Simon Schwoerer, Francesco V Cimino, Manon Ros, Kaloyan M Tsanov, Charles Ng, Scott W Lowe, Carlos Carmona-Fontaine, Craig B Thompson
Hypoxia potentiates the inflammatory fibroblast phenotype promoted by pancreatic cancer cell-derived cytokines. Cancer research (2023)
Loretah Chibaya, Katherine C Murphy, Kelly D DeMarco, Sneha Gopalan, Haibo Liu, Chaitanya N Parikh, Yvette Lopez-Diaz, Melissa Faulkner, Junhui Li, John P Morris, Yu-Jui Ho, Sachliv K Chana, Janelle Simon, Wei Luan, Amanda Kulick, Elisa de Stanchina, Karl Simin, Julie Lihua Zhu, Thomas G Fazzio, Scott W Lowe, Marcus Ruscetti
EZH2 inhibition remodels the inflammatory senescence-associated secretory phenotype to potentiate pancreatic cancer immune surveillance. Nature cancer (2023)
Zhuxuan Li, Xueqian Zhuang, Chun-Hao Pan, Yan Yan, Rohit Thummalapalli, Jill Hallin, Stefan R Torborg, Anupriya Singhal, Jason C Chang, Eusebio Manchado, Lukas E Dow, Rona Yaeger, James G Christensen, Scott W Lowe, Charles M Rudin, Simon Joost, Tuomas Tammela
Alveolar differentiation drives resistance to KRAS inhibition in lung adenocarcinoma. Cancer discovery (2023)
Cassandra Burdziak, Direna Alonso-Curbelo, Thomas Walle, José Reyes, Francisco M Barriga, Doron Haviv, Yubin Xie, Zhen Zhao, Chujun Julia Zhao, Hsuan-An Chen, Ojasvi Chaudhary, Ignas Masilionis, Zi-Ning Choo, Vianne Gao, Wei Luan, Alexandra Wuest, Yu-Jui Ho, Yuhong Wei, Abdel Razaq Ahmad A Alyasin, Richard P Koche, Linas Mazutis, Ronan Chaligné, Tal Nawy, Scott W Lowe, Dana Pe'er
Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis. Science (New York, N.Y.) 380 (6645) (2023)
Karuna Ganesh, Harihar Basnet, Yasemin Kaygusuz, Ashley M Laughney, Lan He, Roshan Sharma, Kevin P O'Rourke, Vincent P Reuter, Yun-Han Huang, Mesruh Turkekul, Ekrem Emrah Er, Ignas Masilionis, Katia Manova-Todorova, Martin R Weiser, Leonard B Saltz, Julio Garcia-Aguilar, Richard P Koche, Scott W Lowe, Dana Pe'er, Jinru Shia, Joan Massagué
Author Correction: L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer. Nature cancer 1 (11) (2023)
Cassandra Burdziak, Direna Alonso-Curbelo, Thomas Walle, José Reyes, Francisco M Barriga, Doron Haviv, Yubin Xie, Zhen Zhao, Chujun Julia Zhao, Hsuan-An Chen, Ojasvi Chaudhary, Ignas Masilionis, Zi-Ning Choo, Vianne Gao, Wei Luan, Alexandra Wuest, Yu-Jui Ho, Yuhong Wei, Abdel Razaq Ahmad A Alyasin, Richard P Koche, Linas Mazutis, Ronan Chaligné, Tal Nawy, Scott W Lowe, Dana Pe'er
Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis. Science (New York, N.Y.) 380 (6645) (2023)
Jing Hu, Francisco J Sánchez Rivera, Zhenghan Wang, Gabriela N Johnson, Yu-Jui Ho, Karuna Ganesh, Shigeaki Umeda, Siting Gan, Adriana M Mujal, Rebecca B Delconte, Jessica P Hampton, Huiyong Zhao, Sanjay Kottapalli, Elisa de Stanchina, Christine A Iacobuzio-Donahue, Dana Pe'er, Scott W Lowe, Joseph C Sun, Joan Massagué
STING inhibits the reactivation of dormant metastasis in lung adenocarcinoma. Nature (2023)
Phillip M Rappold, Lynda Vuong, Josef Leibold, Nicholas H Chakiryan, Michael Curry, Fengshen Kuo, Erich Sabio, Hui Jiang, Briana G Nixon, Ming Liu, Anders E Berglund, Andrew W Silagy, Eduardo A Mascareno, Mahdi Golkaram, Mahtab Marker, Albert Reising, Alexander Savchenko, John M Millholland, Ying-Bei Chen, Paul Russo, Jonathan A Coleman, Ed Reznik, Brandon J Manley, Irina Ostrovnaya, Vladimir Makarov, Renzo G DiNatale, Kyle A Blum, Xiaoxiao Ma, Diego Chowell, Ming O Li, David B Solit, Scott W Lowe, Timothy A Chan, Robert J Motzer, Martin H Voss, Abraham Ari Hakimi
A Targetable Myeloid Inflammatory State Governs Disease Recurrence in Clear-Cell Renal Cell Carcinoma. Cancer discovery 12 (10) (2022)
Rona Yaeger, Riccardo Mezzadra, Jenna Sinopoli, Yu Bian, Michelangelo Marasco, Esther Kaplun, Yijun Gao, HuiYong Zhao, Arnaud Da Cruz Paula, Yingjie Zhu, Almudena Chaves-Pérez, Kalyani Chadalavada, Edison Tse, Sudhir Chowdhry, Sydney Bowker, Qing Chang, Besnik Qeriqi, Jorge S Reis-Filho, Gouri J Nanjangud, Michael F Berger, Hirak Der-Torossian, Kenna Anderes, Nicholas D Socci, Jinru Shia, Gregory J Riely, Yonina R Murciano-Goroff, Bob T Li, James G Christensen, Jorge Sergio Reis-Filho, David B Solit, Elisa De Stanchina, Scott W Lowe, Neal X Rosen, Sandra Misale
Molecular characterization of acquired resistance to KRAS G12C-EGFR inhibition in colorectal cancer. Cancer discovery (2022)
Hsuan-An Chen, Yu-Jui Ho, Riccardo Mezzadra, José María Adrover, Ryan M Smolkin, Changyu Zhu, Katharina Woess, Nicholas Bernstein, Georgia Schmitt, Linda Fong, Wei Luan, Alexandra N Wuest, Sha Tian, Xiang Li, Caroline Broderick, Ronald C Hendrickson, Mikala Egeblad, Zhenghao Chen, Direna Alonso-Curbelo, Scott W Lowe
Senescence rewires microenvironment sensing to facilitate anti-tumor immunity. Cancer discovery (2022)
Francisco M Barriga, Kaloyan M Tsanov, Yu-Jui Ho, Noor Sohail, Amy Zhang, Timour Baslan, Alexandra N Wuest, Isabella Del Priore, Brigita Meškauskaitė, Geulah Livshits, Direna Alonso-Curbelo, Janelle Simon, Almudena Chaves-Perez, Dafna Bar-Sagi, Christine A Iacobuzio-Donahue, Faiyaz Notta, Ronan Chaligné, Roshan Sharma, Dana Pe'er, Scott W Lowe
MACHETE identifies interferon-encompassing chromosome 9p21.3 deletions as mediators of immune evasion and metastasis. Nature cancer 3 (11) (2022)
Sui Seng Tee, Nathaniel Kim, Quinlan E Cullen, Roozbeh Eskandari, Arsen Mamakhanyan, Rami M Srouji, Rachel Chirayil, Sangmoo Jeong, Mojdeh Shakiba, Edward R Kastenhuber, Shuibing Chen, Carlie S Sigel, Scott W Lowe, William R Jarnagin, Craig B Thompson, Andrea Schietinger, Kayvan R Keshari
Ketohexokinase-mediated fructose metabolism is lost in hepatocellular carcinoma and can be leveraged for metabolic imaging. Science advances 8 (14) (2022)
Francisco J Sánchez-Rivera, Bianca J Diaz, Edward R Kastenhuber, Henri Schmidt, Alyna Katti, Margaret C Kennedy, Vincent Tem, Yu-Jui Ho, Josef Leibold, Stella V Paffenholz, Francisco M Barriga, Kevan Chu, Sukanya Goswami, Alexandra N Wuest, Janelle M Simon, Kaloyan M Tsanov, Debyani Chakravarty, Hongxin Zhang, Christina S Leslie, Scott W Lowe, Lukas E Dow
Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants. Nature biotechnology 40 (6) (2022)
Feifei Na, Xiangyu Pan, Jingyao Chen, Xuelan Chen, Manli Wang, Pengliang Chi, Liting You, Lanxin Zhang, Ailing Zhong, Lei Zhao, Siqi Dai, Mengsha Zhang, Yiyun Wang, Bo Wang, Jianan Zheng, Yuying Wang, Jing Xu, Jian Wang, Baohong Wu, Mei Chen, Hongyu Liu, Jianxin Xue, Meijuan Huang, Youling Gong, Jiang Zhu, Lin Zhou, Yan Zhang, Min Yu, Panwen Tian, Mingyu Fan, Zhenghao Lu, Zhihong Xue, Yinglan Zhao, Hanshuo Yang, Chengjian Zhao, Zhongwang Wang, Junhong Han, Shengyong Yang, Dan Xie, Mei Chen, Qian Zhong, Musheng Zeng, Scott W Lowe, You Lu, Yu Liu, Yuquan Wei, Chong Chen
KMT2C deficiency promotes small cell lung cancer metastasis through DNMT3A-mediated epigenetic reprogramming. Nature cancer 3 (6) (2022)
Stella V Paffenholz, Camilla Salvagno, Yu-Jui Ho, Matthew Limjoco, Timour Baslan, Sha Tian, Amanda Kulick, Elisa de Stanchina, John E Wilkinson, Francisco M Barriga, Dmitriy Zamarin, Juan R Cubillos-Ruiz, Josef Leibold, Scott W Lowe
Senescence induction dictates response to chemo- and immunotherapy in preclinical models of ovarian cancer. Proceedings of the National Academy of Sciences of the United States of America 119 (5) (2022)
Timour Baslan, John P Morris, Zhen Zhao, Jose Reyes, Yu-Jui Ho, Kaloyan M Tsanov, Jonathan Bermeo, Sha Tian, Sean Zhang, Gokce Askan, Aslihan Yavas, Nicolas Lecomte, Amanda Erakky, Anna M Varghese, Amy Zhang, Jude Kendall, Elena Ghiban, Lubomir Chorbadjiev, Jie Wu, Nevenka Dimitrova, Kalyani Chadalavada, Gouri J Nanjangud, Chaitanya Bandlamudi, Yixiao Gong, Mark T A Donoghue, Nicholas D Socci, Alex Krasnitz, Faiyaz Notta, Steven D Leach, Christine A Iacobuzio-Donahue, Scott W Lowe
Ordered and deterministic cancer genome evolution after p53 loss. Nature 608 (7924) (2022)
Yadira M Soto-Feliciano, Francisco J Sánchez Rivera, Florian Perner, Douglas W Barrows, Edward R Kastenhuber, Yu-Jui Ho, Thomas S Carroll, Yijun Xiong, Disha Anand, Alexey A Soshnev, Leah A Gates, Mary Clare Beytagh, David Cheon, Shengqing Stan Gu, X Shirley Liu, Andrei V Krivtsov, Maximiliano Meneses, Elisa De Stanchina, Richard M Stone, Scott A Armstrong, Scott W Lowe, C David Allis
A molecular switch between mammalian MLL complexes dictates response to Menin-MLL inhibition. Cancer discovery (2022)
Margaret C Kennedy, Scott W Lowe
Mutant p53: it's not all one and the same. Cell death and differentiation 29 (5) (2022)
Xiang Li, Chun-Hao Huang, Francisco J Sánchez Rivera, Margaret C Kennedy, Darjus F Tschaharganeh, John P Morris, Antonella Montinaro, Kevin P O'Rourke, Ana Banito, John E Wilkinson, Chi-Chao Chen, Yu-Jui Ho, Lukas E Dow, Sha Tian, Wei Luan, Elisa de Stanchina, Tinghu Zhang, Nathanael S Gray, Henning Walczak, Scott W Lowe
A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets. Proceedings of the National Academy of Sciences of the United States of America 119 (17) (2022)
Ravikanth Maddipati, Robert J Norgard, Timour Baslan, Komal S Rathi, Amy Zhang, Asal Saeid, Taku Higashihara, Feng Wu, Angad Kumar, Valli Annamalai, Saurav Bhattacharya, Pichai Raman, Christian A Adkisson, Jason R Pitarresi, Maximilian D Wengyn, Taiji Yamazoe, Jinyang Li, David Balli, Michael J LaRiviere, Tuong-Vi Cindy Ngo, Ian W Folkert, Ian Daniel Millstein, Jonathan Bermeo, Erica L Carpenter, John C McAuliffe, Maja H Oktay, Rolf A Brekken, Scott W Lowe, Christine A Iacobuzio-Donahue, Faiyaz Notta, Ben Z Stanger
MYC levels regulate metastatic heterogeneity in pancreatic adenocarcinoma. Cancer discovery (2021)
Inna Ricardo-Lax, Joseph M Luna, Tran Thi Nhu Thao, Jérémie Le Pen, Yingpu Yu, Hans-Heinrich Hoffmann, William M Schneider, Brandon S Razooky, Javier Fernandez-Martinez, Fabian Schmidt, Yiska Weisblum, Bettina Salome Trüeb, Inês Berenguer Veiga, Kimberly Schmied, Nadine Ebert, Eleftherios Michailidis, Avery A Peace, Francisco J Sánchez Rivera, Scott W Lowe, Michael P Rout, Theodora Hatziioannou, Paul D Bieniasz, John T Poirier, Margaret R MacDonald, Volker Thiel, Charles M Rice
Replication and single-cycle delivery of SARS-CoV-2 replicons. Science (New York, N.Y.) 374 (6571) (2021)
Sofia V Gearty, Friederike Dündar, Paul Zumbo, Gabriel Espinosa-Carrasco, Mojdeh Shakiba, Francisco J Sanchez-Rivera, Nicholas D Socci, Prerak Trivedi, Scott W Lowe, Peter Lauer, Neeman Mohibullah, Agnes Viale, Teresa P DiLorenzo, Doron Betel, Andrea Schietinger
An autoimmune stem-like CD8 T cell population drives type 1 diabetes. Nature (2021)
Mojdeh Shakiba, Paul Zumbo, Gabriel Espinosa-Carrasco, Laura Menocal, Friederike Dündar, Sandra E Carson, Emmanuel M Bruno, Francisco J Sánchez Rivera, Scott W Lowe, Steven Camara, Richard P Koche, Vincent P Reuter, Nicholas D Socci, Benjamin Whitlock, Fella Tamzalit, Morgan Huse, Matthew D Hellmann, Daniel K Wells, Nadine A Defranoux, Doron Betel, Mary Philip, Andrea Schietinger
TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion. The Journal of experimental medicine 219 (2) (2021)
Direna Alonso-Curbelo, Yu-Jui Ho, Cassandra Burdziak, Jesper L V Maag, John P Morris, Rohit Chandwani, Hsuan-An Chen, Kaloyan M Tsanov, Francisco M Barriga, Wei Luan, Nilgun Tasdemir, Geulah Livshits, Elham Azizi, Jaeyoung Chun, John E Wilkinson, Linas Mazutis, Steven D Leach, Richard P Koche, Dana Pe'er, Scott W Lowe
A gene-environment-induced epigenetic program initiates tumorigenesis. Nature 590 (7847) (2021)
Miguel Jiménez-Alcázar, Álvaro Curiel-García, Paula Nogales, Javier Perales-Patón, Alberto J Schuhmacher, Marcos Galán-Ganga, Lucía Zhu, Scott W Lowe, Fátima Al-Shahrour, Massimo Squatrito
Dianhydrogalactitol Overcomes Multiple Temozolomide Resistance Mechanisms in Glioblastoma. Molecular cancer therapeutics 20 (6) (2021)
Corina Amor, Judith Feucht, Josef Leibold, Yu-Jui Ho, Changyu Zhu, Direna Alonso-Curbelo, Jorge Mansilla-Soto, Jacob A Boyer, Xiang Li, Theodoros Giavridis, Amanda Kulick, Shauna Houlihan, Ellinor Peerschke, Scott L Friedman, Vladimir Ponomarev, Alessandra Piersigilli, Michel Sadelain, Scott W Lowe
Senolytic CAR T cells reverse senescence-associated pathologies. Nature 583 (7814) (2020)
Karuna Ganesh, Harihar Basnet, Yasemin Kaygusuz, Ashley M Laughney, Lan He, Roshan Sharma, Kevin P O'Rourke, Vincent P Reuter, Yun-Han Huang, Mesruh Turkekul, Ekrem Emrah, Ignas Masilionis, Katia Manova-Todorova, Martin R Weiser, Leonard B Saltz, Julio Garcia-Aguilar, Richard P Koche, Scott W Lowe, Dana Pe'er, Jinru Shia, Joan Massagué
L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer. Nature cancer 1 (1) (2020)
Mei Chen, Shujun Li, Xiangyu Pan, Yanqiu Gong, Jianan Zheng, Jing Xu, Chengjian Zhao, Qi Zhang, Shan Zhang, Lu Qi, Zhongwang Wang, Kaidou Shi, Bi-Sen Ding, Zhihong Xue, Shengyong Yang, Ting Niu, Lunzhi Dai, Scott W Lowe, Chong Chen, Yu Liu
An Epigenetic Mechanism Underlying Chromosome 17p Deletion-Driven Tumorigenesis. Cancer discovery 11 (1) (2020)
Alexander N Gorelick, Francisco J Sánchez Rivera, Yanyan Cai, Craig M Bielski, Evan Biederstedt, Philip Jonsson, Allison L Richards, Neil Vasan, Alexander V Penson, Noah D Friedman, Yu-Jui Ho, Timour Baslan, Chaitanya Bandlamudi, Maurizio Scaltriti, Nikolaus Schultz, Scott W Lowe, Ed Reznik, Barry S Taylor
Phase and context shape the function of composite oncogenic mutations. Nature 582 (7810) (2020)
Sheng F Cai, S Haihua Chu, Aaron D Goldberg, Salma Parvin, Richard P Koche, Jacob L Glass, Eytan M Stein, Martin S Tallman, Filiz Sen, Christopher A Famulare, Monica Cusan, Chun-Hao Huang, Chun-Wei David Chen, Lihua Zou, Keith B Cordner, Nicole L DelGaudio, Vidushi Durani, Mitali Kini, Madison Rex, Helen S Tian, Johannes Zuber, Timour Baslan, Scott W Lowe, Hugh Y Rienhoff, Anthony Letai, Ross L Levine, Scott A Armstrong
Leukemia Cell of Origin Influences Apoptotic Priming and Sensitivity to LSD1 Inhibition. Cancer discovery 10 (10) (2020)
William M Schneider, Joseph M Luna, Hans-Heinrich Hoffmann, Francisco J Sánchez Rivera, Andrew A Leal, Alison W Ashbrook, Jérémie Le Pen, Eleftherios Michailidis, Inna Ricardo-Lax, Avery Peace, Ansgar F Stenzel, Scott W Lowe, Margaret R MacDonald, Charles M Rice, John T Poirier
Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks. bioRxiv : the preprint server for biology (2020)
Josef Leibold, Marcus Ruscetti, Zhen Cao, Yu-Jui Ho, Timour Baslan, Min Zou, Wassim Abida, Judith Feucht, Teng Han, Francisco M Barriga, Kaloyan M Tsanov, Leah B Zamechek, Amanda Kulick, Corina Amor, Sha Tian, Katarzyna Rybczyk, Nelson R Salgado, Francisco J Sánchez Rivera, Philip A Watson, Elisa de Stanchina, John E Wilkinson, Lukas E Dow, Cory Abate-Shen, Charles L Sawyers, Scott W Lowe
Somatic Tissue Engineering in Mouse Models Reveals an Actionable Role for WNT Pathway Alterations in Prostate Cancer Metastasis. Cancer discovery 10 (7) (2020)
Hans-Heinrich Hoffmann, William M Schneider, Francisco J Sánchez Rivera, Joseph M Luna, Alison W Ashbrook, Yadira M Soto-Feliciano, Andrew A Leal, Jérémie Le Pen, Inna Ricardo-Lax, Eleftherios Michailidis, Yuan Hao, Ansgar F Stenzel, Avery Peace, C David Allis, Scott W Lowe, Margaret R MacDonald, John T Poirier, Charles M Rice
Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors. bioRxiv : the preprint server for biology (2020)
Karuna Ganesh, Chao Wu, Kevin P O'Rourke, Bryan C Szeglin, Youyun Zheng, Charles-Etienne Gabriel Sauvé, Mohammad Adileh, Isaac Wasserman, Michael R Marco, Amanda S Kim, Maha Shady, Francisco Sanchez-Vega, Wouter R Karthaus, Helen H Won, Seo-Hyun Choi, Raphael Pelossof, Afsar Barlas, Peter Ntiamoah, Emmanouil Pappou, Arthur Elghouayel, James S Strong, Chin-Tung Chen, Jennifer W Harris, Martin R Weiser, Garrett M Nash, Jose G Guillem, Iris H Wei, Richard N Kolesnick, Harini Veeraraghavan, Eduardo J Ortiz, Iva Petkovska, Andrea Cercek, Katia O Manova-Todorova, Leonard B Saltz, Jessica A Lavery, Ronald P DeMatteo, Joan Massagué, Philip B Paty, Rona Yaeger, Xi Chen, Sujata Patil, Hans Clevers, Michael F Berger, Scott W Lowe, Jinru Shia, Paul B Romesser, Lukas E Dow, Julio Garcia-Aguilar, Charles L Sawyers, J Joshua Smith
A rectal cancer organoid platform to study individual responses to chemoradiation. Nature medicine 25 (10) (2019)
Paul B Romesser, Amanda S Kim, Jeho Jeong, Allison Mayle, Lukas E Dow, Scott W Lowe
Preclinical murine platform to evaluate therapeutic countermeasures against radiation-induced gastrointestinal syndrome. Proceedings of the National Academy of Sciences of the United States of America 116 (41) (2019)
Marcus Ruscetti, Josef Leibold, Matthew J Bott, Myles Fennell, Amanda Kulick, Nelson R Salgado, Chi-Chao Chen, Yu-Jui Ho, Francisco J Sanchez-Rivera, Judith Feucht, Timour Baslan, Sha Tian, Hsuan-An Chen, Paul B Romesser, John T Poirier, Charles M Rudin, Elisa De Stanchina, Eusebio Manchado, Charles J Sherr, Scott W Lowe
NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination. Science (New York, N.Y.) 362 (6421) (2019)
Evangelia Loizou, Ana Banito, Geulah Livshits, Yu-Jui Ho, Richard P Koche, Francisco J Sánchez-Rivera, Allison Mayle, Chi-Chao Chen, Savvas Kinalis, Frederik Otzen Bagger, Edward R Kastenhuber, Benjamin H Durham, Scott W Lowe
A Gain-of-Function p53-Mutant Oncogene Promotes Cell Fate Plasticity and Myeloid Leukemia through the Pluripotency Factor FOXH1. Cancer discovery 9 (7) (2019)
Gil Redelman-Sidi, Anna Binyamin, Isabella Gaeta, Wilhelm Palm, Craig B Thompson, Paul B Romesser, Scott W Lowe, Mukta Bagul, John G Doench, David E Root, Michael S Glickman
The Canonical Wnt Pathway Drives Macropinocytosis in Cancer. Cancer research 78 (16) (2018)
Geulah Livshits, Direna Alonso-Curbelo, John P Morris, Richard P Koche, Michael Saborowski, John Erby Wilkinson, Scott W Lowe
Arid1a restrains Kras-dependent changes in acinar cell identity. eLife 7 (2018)
Maria Paz Zafra, Emma M Schatoff, Alyna Katti, Miguel Foronda, Marco Breinig, Anabel Y Schweitzer, Amber Simon, Teng Han, Sukanya Goswami, Emma Montgomery, Jordana Thibado, Edward R Kastenhuber, Francisco J Sánchez-Rivera, Junwei Shi, Christopher R Vakoc, Scott W Lowe, Darjus F Tschaharganeh, Lukas E Dow
Optimized base editors enable efficient editing in cells, organoids and mice. Nature biotechnology 36 (9) (2018)

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