CPT: pharmacometrics & systems pharmacology

Keyphrases

Publications

volume 13, number 7, 2024

Xianhuan Shen, Xuejuan Li, Jieluan Lu, Jiahao Zhu, Yaodong He, Zhou Zhang, Zebin Chen, Jianping Zhang, Xiaomei Fan, Wenzhou Li
Population pharmacokinetic analysis for dose regimen optimization of vancomycin in Southern Chinese children. CPT: pharmacometrics & systems pharmacology 13 (7) (2024)
Xinyuan Zhang, Ping Zhao
Is PBPK useful to inform product label on managing clinically significant drug interactions mediated by cytokine release syndrome? CPT: pharmacometrics & systems pharmacology 13 (7) (2024)
Wenlian Qiao, Martin Boucher, Alison Slade, Vikas K Dawra
Natural disease course modeling of achondroplasia to evaluate the efficacy of recifercept in the absence of a placebo control arm in phase II study. CPT: pharmacometrics & systems pharmacology 13 (7) (2024)
Gaelle Baudemont, Coralie Tardivon, Guillaume Monneret, Martin Cour, Thomas Rimmelé, Lorna Garnier, Hodane Yonis, Jean-Christophe Richard, Remy Coudereau, Morgane Gossez, Florent Wallet, Marie-Charlotte Delignette, Frederic Dailler, Marielle Buisson, Anne-Claire Lukaszewicz, Laurent Argaud, Cédric Laouénan, Julie Bertrand, Fabienne Venet, null null
Joint modeling of monocyte HLA-DR expression trajectories predicts 28-day mortality in severe SARS-CoV-2 patients. CPT: pharmacometrics & systems pharmacology 13 (7) (2024)
Toshiaki Tsuchitani, Atsuko Tomaru, Yasunori Aoki, Naoki Ishiguro, Yasuhiro Tsuda, Yuichi Sugiyama
Elucidating nonlinear pharmacokinetics of telmisartan: Integration of target-mediated drug disposition and OATP1B3-mediated hepatic uptake in a physiologically based model. CPT: pharmacometrics & systems pharmacology 13 (7) (2024)
Simone Perazzolo
SAAM II: A general mathematical modeling rapid prototyping environment. CPT: pharmacometrics & systems pharmacology 13 (7) (2024)
Christina Schräpel, Helena Leonie Hanae Loer, Simeon Rüdesheim, Laura Maria Fuhr, Fatima Zahra Marok, Dominik Selzer, Matthias Schwab, Thorsten Lehr
A physiologically-based pharmacokinetic precision dosing approach to manage dasatinib drug-drug interactions. CPT: pharmacometrics & systems pharmacology 13 (7) (2024)
Thibaud Derippe, Sylvain Fouliard, Xavier Declèves, Donald E Mager
Quantitative systems pharmacology modeling of tumor heterogeneity in response to BH3-mimetics using virtual tumors calibrated with cell viability assays. CPT: pharmacometrics & systems pharmacology 13 (7) (2024)
Mario González-Sales, Ashley L Lennox, Fei Huang, Chandra Pamulapati, Ying Wan, Libo Sun, Tymara Berry, Melissa Kelly Behrs, Faye Feller, Peter N Morcos
Population pharmacokinetics of imetelstat, a first-in-class oligonucleotide telomerase inhibitor. CPT: pharmacometrics & systems pharmacology 13 (7) (2024)
Toshiaki Tsuchitani, Atsuko Tomaru, Yasunori Aoki, Naoki Ishiguro, Yasuhiro Tsuda, Yuichi Sugiyama
Elucidating nonlinear pharmacokinetics of telmisartan: Integration of target-mediated drug disposition and OATP1B3-mediated hepatic uptake in a physiologically based model. CPT: pharmacometrics & systems pharmacology 13 (7) (2024)
Douglas E James, Tong Shen, Jeanne S Geiser, Parag Garhyan, Emmanuel Chigutsa
Population pharmacokinetics and pharmacodynamics of nasal glucagon in patients with type 1 or 2 diabetes. CPT: pharmacometrics & systems pharmacology 13 (7) (2024)
Marie-Emilie Willemin, Shun Xin Wang Lin, Loeckie De Zwart, Liviawati S Wu, Xin Miao, Raluca Verona, Arnob Banerjee, Baolian Liu, Rachel Kobos, Ming Qi, Daniele Ouellet, Jenna D Goldberg, Suzette Girgis
Evaluating drug interaction potential from cytokine release syndrome using a physiologically based pharmacokinetic model: A case study of teclistamab. CPT: pharmacometrics & systems pharmacology 13 (7) (2024)
Mohammadali Alidoost, Jennifer L Wilson
Preclinical side effect prediction through pathway engineering of protein interaction network models. CPT: pharmacometrics & systems pharmacology 13 (7) (2024)
Peng Chen, Yanyan Zhang, Yike Wang, Ke Ma, Wei Shi, Nassim Djebli, Kai Shen
Population pharmacokinetics of adebrelimab - Support of alternative flat dose regimen in extensive-stage small-cell lung cancer. CPT: pharmacometrics & systems pharmacology 13 (7) (2024)

volume 13, number 8, 2024

Alzahra Hamdan, Andrew C Hooker, Xiaomei Chen, Andreas Traschütz, Rebecca Schüle, null null, null null, Matthis Synofzik, Mats O Karlson
Item performance of the scale for the assessment and rating of ataxia in rare and ultra-rare genetic ataxias. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Arya Pourzanjani, Saurabh Modi, Jamie N Connarn, Xinwen Zhang, Vijay V Upreti, Chih-Wei Lin, Khamir Mehta
A novel Bayesian generative approach for estimating tumor dynamics from published studies. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
E Niclas Jonsson, Joakim Nyberg
Full random effects models (FREM): A practical usage guide. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Raunak Dutta, Aparna Mohan, Jacqueline Buros-Novik, Gregory Goldmacher, Omobolaji O Akala, Brian Topp
A bootstrapping method to optimize go/no-go decisions from single-arm, signal-finding studies in oncology. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Juan Francisco Morales, Marian Klose, Yannick Hoffert, Jagdeep T Podichetty, Jackson Burton, Stephan Schmidt, Klaus Romero, Inish O'Doherty, Frank Martin, Martha Campbell-Thompson, Michael J Haller, Mark A Atkinson, Sarah Kim
Type 1 diabetes prevention clinical trial simulator: Case reports of model-informed drug development tool. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Idris Bachali Losada, Nadia Terranova
Bridging pharmacology and neural networks: A deep dive into neural ordinary differential equations. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Arya Pourzanjani, Saurabh Modi, Jamie N Connarn, Xinwen Zhang, Vijay V Upreti, Chih-Wei Lin, Khamir Mehta
A novel Bayesian generative approach for estimating tumor dynamics from published studies. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Alzahra Hamdan, Andrew C Hooker, Xiaomei Chen, Andreas Traschütz, Rebecca Schüle, null null, null null, Matthis Synofzik, Mats O Karlson
Item performance of the scale for the assessment and rating of ataxia in rare and ultra-rare genetic ataxias. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Alzahra Hamdan, Andrew C Hooker, Xiaomei Chen, Andreas Traschütz, Rebecca Schüle, null null, null null, Matthis Synofzik, Mats O Karlson
Item performance of the scale for the assessment and rating of ataxia in rare and ultra-rare genetic ataxias. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Sebastiaan Camiel Goulooze, Martijn van Noort
Time-varying covariates, overadjustment bias and mediation in pharmacokinetic/pharmacodynamic modeling. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Raunak Dutta, Aparna Mohan, Jacqueline Buros-Novik, Gregory Goldmacher, Omobolaji O Akala, Brian Topp
A bootstrapping method to optimize go/no-go decisions from single-arm, signal-finding studies in oncology. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Sihem Ait-Oudhia, David Jaworowicz, Ziheng Hu, Sébastien Bihorel, Shuai Hu, Budda Balasubrahmanyam, Bipin Mistry, Janethe de Oliveira Pena, Larissa Wenning, Ferdous Gheyas
Population pharmacokinetic modeling of sotatercept in healthy participants and patients with pulmonary arterial hypertension. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Idris Bachali Losada, Nadia Terranova
Bridging pharmacology and neural networks: A deep dive into neural ordinary differential equations. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Sebastiaan Camiel Goulooze, Martijn van Noort
Time-varying covariates, overadjustment bias and mediation in pharmacokinetic/pharmacodynamic modeling. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Juan Francisco Morales, Marian Klose, Yannick Hoffert, Jagdeep T Podichetty, Jackson Burton, Stephan Schmidt, Klaus Romero, Inish O'Doherty, Frank Martin, Martha Campbell-Thompson, Michael J Haller, Mark A Atkinson, Sarah Kim
Type 1 diabetes prevention clinical trial simulator: Case reports of model-informed drug development tool. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Conor J O'Hanlon, Nick H G Holford, Brian Joseph Anderson, Mark Greaves, Lee Blackburn, Malcolm Drummond Tingle, Jacqueline A Hannam
A pharmacokinetic framework describing antibiotic adsorption to cardiopulmonary bypass devices. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Noriko Okudaira, Howard Burt, Amitava Mitra
Tipifarnib physiologically-based pharmacokinetic modeling to assess drug-drug interaction, organ impairment, and biopharmaceutics in healthy subjects and cancer patients. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Juan Francisco Morales, Marian Klose, Yannick Hoffert, Jagdeep T Podichetty, Jackson Burton, Stephan Schmidt, Klaus Romero, Inish O'Doherty, Frank Martin, Martha Campbell-Thompson, Michael J Haller, Mark A Atkinson, Sarah Kim
Type 1 diabetes prevention clinical trial simulator: Case reports of model-informed drug development tool. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
E Niclas Jonsson, Joakim Nyberg
Full random effects models (FREM): A practical usage guide. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Arya Pourzanjani, Saurabh Modi, Jamie N Connarn, Xinwen Zhang, Vijay V Upreti, Chih-Wei Lin, Khamir Mehta
A novel Bayesian generative approach for estimating tumor dynamics from published studies. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Conor J O'Hanlon, Nick H G Holford, Brian Joseph Anderson, Mark Greaves, Lee Blackburn, Malcolm Drummond Tingle, Jacqueline A Hannam
A pharmacokinetic framework describing antibiotic adsorption to cardiopulmonary bypass devices. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Idris Bachali Losada, Nadia Terranova
Bridging pharmacology and neural networks: A deep dive into neural ordinary differential equations. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Sihem Ait-Oudhia, David Jaworowicz, Ziheng Hu, Sébastien Bihorel, Shuai Hu, Budda Balasubrahmanyam, Bipin Mistry, Janethe de Oliveira Pena, Larissa Wenning, Ferdous Gheyas
Population pharmacokinetic modeling of sotatercept in healthy participants and patients with pulmonary arterial hypertension. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Elizabeth J Thompson, Angela Jeong, Victória Etges Helfer, Valentina Shakhnovich, Andrea N Edginton, Stephen J Balevic, Laura P James, David N Collier, Ravinder Anand, Daniel Gonzalez, null null
Physiologically-based pharmacokinetic modeling of pantoprazole to evaluate the role of CYP2C19 genetic variation and obesity in the pediatric population. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Raunak Dutta, Aparna Mohan, Jacqueline Buros-Novik, Gregory Goldmacher, Omobolaji O Akala, Brian Topp
A bootstrapping method to optimize go/no-go decisions from single-arm, signal-finding studies in oncology. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Daichi Yamaguchi, Ryosuke Shimizu, Ryuji Kubota
Development of a SARS-CoV-2 viral dynamic model for patients with COVID-19 based on the amount of viral RNA and viral titer. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Noriko Okudaira, Howard Burt, Amitava Mitra
Tipifarnib physiologically-based pharmacokinetic modeling to assess drug-drug interaction, organ impairment, and biopharmaceutics in healthy subjects and cancer patients. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Elizabeth J Thompson, Angela Jeong, Victória Etges Helfer, Valentina Shakhnovich, Andrea N Edginton, Stephen J Balevic, Laura P James, David N Collier, Ravinder Anand, Daniel Gonzalez, null null
Physiologically-based pharmacokinetic modeling of pantoprazole to evaluate the role of CYP2C19 genetic variation and obesity in the pediatric population. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Sebastiaan Camiel Goulooze, Martijn van Noort
Time-varying covariates, overadjustment bias and mediation in pharmacokinetic/pharmacodynamic modeling. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Sihem Ait-Oudhia, David Jaworowicz, Ziheng Hu, Sébastien Bihorel, Shuai Hu, Budda Balasubrahmanyam, Bipin Mistry, Janethe de Oliveira Pena, Larissa Wenning, Ferdous Gheyas
Population pharmacokinetic modeling of sotatercept in healthy participants and patients with pulmonary arterial hypertension. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Noriko Okudaira, Howard Burt, Amitava Mitra
Tipifarnib physiologically-based pharmacokinetic modeling to assess drug-drug interaction, organ impairment, and biopharmaceutics in healthy subjects and cancer patients. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Daichi Yamaguchi, Ryosuke Shimizu, Ryuji Kubota
Development of a SARS-CoV-2 viral dynamic model for patients with COVID-19 based on the amount of viral RNA and viral titer. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Elizabeth J Thompson, Angela Jeong, Victória Etges Helfer, Valentina Shakhnovich, Andrea N Edginton, Stephen J Balevic, Laura P James, David N Collier, Ravinder Anand, Daniel Gonzalez, null null
Physiologically-based pharmacokinetic modeling of pantoprazole to evaluate the role of CYP2C19 genetic variation and obesity in the pediatric population. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
E Niclas Jonsson, Joakim Nyberg
Full random effects models (FREM): A practical usage guide. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Conor J O'Hanlon, Nick H G Holford, Brian Joseph Anderson, Mark Greaves, Lee Blackburn, Malcolm Drummond Tingle, Jacqueline A Hannam
A pharmacokinetic framework describing antibiotic adsorption to cardiopulmonary bypass devices. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)
Daichi Yamaguchi, Ryosuke Shimizu, Ryuji Kubota
Development of a SARS-CoV-2 viral dynamic model for patients with COVID-19 based on the amount of viral RNA and viral titer. CPT: pharmacometrics & systems pharmacology 13 (8) (2024)