Finian J Leeper

ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 22

Top Venues

Organic & biomolecular chemistry

Cancers

RSC medicinal chemistry

ACS medicinal chemistry letters

University of Cambridge

University of Cambridge (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Cambridge

United Kingdom

now Senior Lecturer :: Chemistry

Education History

University of Cambridge

United Kingdom

PHD :: Chemistry

Publications

Alex H Y Chan, Terence C S Ho, Imam Fathoni, Zhoor Hamid, Anna K H Hirsch, Kevin J Saliba, Finian J Leeper
Evaluation of ketoclomazone and its analogues as inhibitors of 1-deoxy-d-xylulose 5-phosphate synthases and other thiamine diphosphate (ThDP)-dependent enzymes. RSC medicinal chemistry 15 (5) (2024)
Alex H Y Chan, Terence C S Ho, Imam Fathoni, Zhoor Hamid, Anna K H Hirsch, Kevin J Saliba, Finian J Leeper
Evaluation of ketoclomazone and its analogues as inhibitors of 1-deoxy-d-xylulose 5-phosphate synthases and other thiamine diphosphate (ThDP)-dependent enzymes. RSC medicinal chemistry 15 (5) (2024)
Gabriel S de Oliveira, Priscila Dos S Bury, Fanglu Huang, Yuan Li, Natália C de Araújo, Jiahai Zhou, Yuhui Sun, Finian J Leeper, Peter F Leadlay, Marcio Vinicius Bertacine Dias
Structural and Functional Basis of GenB2 Isomerase Activity from Gentamicin Biosynthesis. ACS chemical biology (2024)
Alex H Y Chan, Terence C S Ho, Imam Fathoni, Rebecca Pope, Kevin J Saliba, Finian J Leeper
Inhibition of Thiamine Diphosphate-Dependent Enzymes by Triazole-Based Thiamine Analogues. ACS medicinal chemistry letters 14 (5) (2023)
Alex H Y Chan, Terence C S Ho, Daniel R Parle, Finian J Leeper
Furan-based inhibitors of pyruvate dehydrogenase: SAR study, biochemical evaluation and computational analysis. Organic & biomolecular chemistry 21 (8) (2023)
Alex H Y Chan, Terence C S Ho, Finian J Leeper
Open-chain thiamine analogues as potent inhibitors of thiamine pyrophosphate (TPP)-dependent enzymes. Organic & biomolecular chemistry (2023)
Alex H Y Chan, Terence C S Ho, Imam Fathoni, Rebecca Pope, Kevin J Saliba, Finian J Leeper
Inhibition of Thiamine Diphosphate-Dependent Enzymes by Triazole-Based Thiamine Analogues. ACS medicinal chemistry letters 14 (5) (2023)
Flaviu Bulat, Friederike Hesse, Bala Attili, Chandra Solanki, Iosif A Mendichovszky, Franklin Aigbirhio, Finian J Leeper, Kevin M Brindle, André A Neves
Preclinical PET Imaging of Tumor Cell Death following Therapy Using Gallium-68-Labeled C2Am. Cancers 15 (5) (2023)
Alex H Y Chan, Terence C S Ho, Daniel R Parle, Finian J Leeper
Furan-based inhibitors of pyruvate dehydrogenase: SAR study, biochemical evaluation and computational analysis. Organic & biomolecular chemistry 21 (8) (2023)
Alex H Y Chan, Terence C S Ho, Daniel R Parle, Finian J Leeper
Furan-based inhibitors of pyruvate dehydrogenase: SAR study, biochemical evaluation and computational analysis. Organic & biomolecular chemistry 21 (8) (2023)
Flaviu Bulat, Friederike Hesse, Bala Attili, Chandra Solanki, Iosif A Mendichovszky, Franklin Aigbirhio, Finian J Leeper, Kevin M Brindle, André A Neves
Preclinical PET Imaging of Tumor Cell Death following Therapy Using Gallium-68-Labeled C2Am. Cancers 15 (5) (2023)
Annabel C Murphy, Matthew Corney, Rita E Monson, Miguel A Matilla, George P C Salmond, Finian J Leeper
Biosynthesis of Antifungal Solanimycin May Involve an Iterative Nonribosomal Peptide Synthetase Module. ACS chemical biology (2023)
Alex H Y Chan, Terence C S Ho, Daniel R Parle, Finian J Leeper
Furan-based inhibitors of pyruvate dehydrogenase: SAR study, biochemical evaluation and computational analysis. Organic & biomolecular chemistry (2023)
Oksana Bilyk, Gabriel S Oliveira, Rafaela M de Angelo, Michell O Almeida, Kathia Maria Honório, Finian J Leeper, Marcio Vinicius Bertacine Dias, Peter F Leadlay
Enzyme-Catalyzed Spiroacetal Formation in Polyketide Antibiotic Biosynthesis. Journal of the American Chemical Society 144 (32) (2022)
Daniel R Parle, Flaviu Bulat, Shahd Fouad, Heather Zecchini, Kevin M Brindle, André A Neves, Finian J Leeper
Metabolic Glycan Labeling of Cancer Cells Using Variably Acetylated Monosaccharides. Bioconjugate chemistry 33 (8) (2022)
Emma S Rudge, Alex H Y Chan, Finian J Leeper
Prodrugs of pyrophosphates and bisphosphonates: disguising phosphorus oxyanions. RSC medicinal chemistry 13 (4) (2022)
Alex H Y Chan, Imam Fathoni, Terence C S Ho, Kevin J Saliba, Finian J Leeper
Thiamine analogues as inhibitors of pyruvate dehydrogenase and discovery of a thiamine analogue with non-thiamine related antiplasmodial activity. RSC medicinal chemistry 13 (7) (2022)
Alex H Y Chan, Terence C S Ho, Kwasi Agyei-Owusu, Finian J Leeper
Synthesis of pyrrothiamine, a novel thiamine analogue, and evaluation of derivatives as potent and selective inhibitors of pyruvate dehydrogenase. Organic & biomolecular chemistry 20 (45) (2022)
Maxime Couturier, Hiral D Bhalara, Rita E Monson, George P C Salmond, Finian J Leeper
Revision in the first steps of the biosynthesis of the red antibiotic prodigiosin: use of a synthetic thioester to validate a new intermediate. RSC chemical biology 2 (2) (2021)
Maxime Couturier, Hiral D Bhalara, Suresh R Chawrai, Rita Monson, Neil R Williamson, George P C Salmond, Finian J Leeper
Substrate Flexibility of the Flavin-Dependent Dihydropyrrole Oxidases PigB and HapB Involved in Antibiotic Prodigiosin Biosynthesis. Chembiochem : a European journal of chemical biology 21 (4) (2019)
André A Neves, Yéléna A Wainman, Alan Wright, Mikko I Kettunen, Tiago B Rodrigues, Sarah McGuire, De-En Hu, Flaviu Bulat, Simonetta Geninatti Crich, Henning Stöckmann, Finian J Leeper, Kevin M Brindle
Imaging Glycosylation In Vivo by Metabolic Labeling and Magnetic Resonance Imaging. Angewandte Chemie (International ed. in English) 55 (4) (2015)
André A Neves, Yéléna A Wainman, Alan Wright, Mikko I Kettunen, Tiago B Rodrigues, Sarah McGuire, De-En Hu, Flaviu Bulat, Simonetta Geninatti Crich, Henning Stöckmann, Finian J Leeper, Kevin M Brindle
Imaging Glycosylation In Vivo by Metabolic Labeling and Magnetic Resonance Imaging. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 128 (4) (2015)

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Publication Activity (10 Years)

Top Topics

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Finian J Leeper