Frances Mary Platt (Frances Platt, Frances M Platt)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 33

Top Venues

Wellcome open research

International journal of molecular sciences

Biomolecules

Cells

University of Oxford

University of Bath (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Oxford Aug 1o 2008

United Kingdom

Professor of Biochemistry and Pharmacology :: Pharmacology

Education History

University of Bath Oct 1o 1982 - Sep 30o 1985

United Kingdom

PHD :: Animal Physiology

Publications

Michael Paul Hughes, Hemanth Ramesh Nelvagal, Oliver Coombe-Tennant, David A Smith, Claire Smith, Giulia Massaro, Laura Poupon-Bejuit, Frances Mary Platt, Ahad Abdul Rahim
A Novel Small NPC1 Promoter Enhances AAV-Mediated Gene Therapy in Mouse Models of Niemann-Pick Type C1 Disease. Cells 12 (12) (2023)
Anyelo Durán, David A Priestman, Macarena Las Heras, Boris Rebolledo-Jaramillo, Valeria Olguín, Juan Francisco Calderón, Silvana Zanlungo, Jaime Gutiérrez, Frances Mary Platt, Andrés D Klein
A Mouse Systems Genetics Approach Reveals Common and Uncommon Genetic Modifiers of Hepatic Lysosomal Enzyme Activities and Glycosphingolipids. International journal of molecular sciences 24 (5) (2023)
Antonino Puglisi, Noemi Bognanni, Graziella Vecchio, Ece Bayir, Peter van Oostrum, Dawn Shepherd, Frances Mary Platt, Erik Reimhult
Grafting of Cyclodextrin to Theranostic Nanoparticles Improves Blood-Brain Barrier Model Crossing. Biomolecules 13 (3) (2023)
Anyelo Durán, David A Priestman, Macarena Las Heras, Boris Rebolledo-Jaramillo, Valeria Olguín, Juan Francisco Calderón, Silvana Zanlungo, Jaime Gutiérrez, Frances Mary Platt, Andrés D Klein
A Mouse Systems Genetics Approach Reveals Common and Uncommon Genetic Modifiers of Hepatic Lysosomal Enzyme Activities and Glycosphingolipids. International journal of molecular sciences 24 (5) (2023)
Anyelo Durán, David A Priestman, Macarena Las Heras, Boris Rebolledo-Jaramillo, Valeria Olguín, Juan Francisco Calderón, Silvana Zanlungo, Jaime Gutiérrez, Frances Mary Platt, Andrés D Klein
A Mouse Systems Genetics Approach Reveals Common and Uncommon Genetic Modifiers of Hepatic Lysosomal Enzyme Activities and Glycosphingolipids. International journal of molecular sciences 24 (5) (2023)
Michael Paul Hughes, Hemanth Ramesh Nelvagal, Oliver Coombe-Tennant, David A Smith, Claire Smith, Giulia Massaro, Laura Poupon-Bejuit, Frances Mary Platt, Ahad Abdul Rahim
A Novel Small NPC1 Promoter Enhances AAV-Mediated Gene Therapy in Mouse Models of Niemann-Pick Type C1 Disease. Cells 12 (12) (2023)
Antonino Puglisi, Noemi Bognanni, Graziella Vecchio, Ece Bayir, Peter van Oostrum, Dawn Shepherd, Frances Mary Platt, Erik Reimhult
Grafting of Cyclodextrin to Theranostic Nanoparticles Improves Blood-Brain Barrier Model Crossing. Biomolecules 13 (3) (2023)
Michael Paul Hughes, Hemanth Ramesh Nelvagal, Oliver Coombe-Tennant, David A Smith, Claire Smith, Giulia Massaro, Laura Poupon-Bejuit, Frances Mary Platt, Ahad Abdul Rahim
A Novel Small NPC1 Promoter Enhances AAV-Mediated Gene Therapy in Mouse Models of Niemann-Pick Type C1 Disease. Cells 12 (12) (2023)
Antonino Puglisi, Noemi Bognanni, Graziella Vecchio, Ece Bayir, Peter van Oostrum, Dawn Shepherd, Frances Mary Platt, Erik Reimhult
Grafting of Cyclodextrin to Theranostic Nanoparticles Improves Blood-Brain Barrier Model Crossing. Biomolecules 13 (3) (2023)
Frances Mary Platt
The expanding boundaries of sphingolipid lysosomal storage diseases; insights from Niemann-Pick disease type C. Biochemical Society transactions (2023)
Duarte C Barral, Leopoldo Staiano, Cláudia Guimas Almeida, Dan F Cutler, Emily R Eden, Clare E Futter, Antony Galione, André R A Marques, Diego Luis Medina, Gennaro Napolitano, Carmine Settembre, Otília V Vieira, Johannes M F G Aerts, Peace Atakpa-Adaji, Gemma Bruno, Antonella Capuozzo, Elvira De Leonibus, Chiara Di Malta, Cristina Escrevente, Alessandra Esposito, Paolo Grumati, Michael J Hall, Rita O Teodoro, Susana Santos Lopes, J Paul Luzio, Jlenia Monfregola, Sandro Montefusco, Frances Mary Platt, Roman S Polishchuk, Maria De Risi, Irene Sambri, Chiara Soldati, Miguel C Seabra
Current methods to analyze lysosome morphology, positioning, motility and function. Traffic (Copenhagen, Denmark) 23 (5) (2022)
Isabelle Williams, Sumeet Pandey, Wolfram Haller, Hien Quoc Huynh, Alicia Chan, Gesche Düeker, Ruth Bettels, Laurent Peyrin-Biroulet, Chinenye R Dike, Catherine DeGeeter, David A Smith, Nada Al Eisa, Nick Platt, Thorsten Marquardt, Tobias Schwerd, Frances Mary Platt, Holm H Uhlig
Anti-TNF therapy for inflammatory bowel disease in patients with neurodegenerative Niemann-Pick disease Type C. Wellcome open research 7 (2022)
Xuefang Pan, Mahsa Taherzadeh, Poulomee Bose, Rachel Heon-Roberts, Annie L A Nguyen, TianMeng Xu, Camila Pará, Yojiro Yamanaka, David A Priestman, Frances Mary Platt, Shaukat Khan, Nidhi Fnu, Shunji Tomatsu, Carlos R Morales, Alexey V Pshezhetsky
Glucosamine amends CNS pathology in mucopolysaccharidosis IIIC mouse expressing misfolded HGSNAT. The Journal of experimental medicine 219 (8) (2022)
Oscar C W Chen, Stephan Siebel, Alexandria Colaco, Elena-Raluca Nicoli, Nick Platt, Dawn Shepherd, Stephanie Newman, Andrew E Armitage, Nicole Y Farhat, George Seligmann, Claire Smith, David A Smith, Alaa Abdul-Sada, Mylvaganam Jeyakumar, Hal Drakesmith, Forbes D Porter, Frances Mary Platt
Defective iron homeostasis and hematological abnormalities in Niemann-Pick disease type C1. Wellcome open research 7 (2022)
Yuzhe Weng, Dawn Shepherd, Yi Liu, Nitya Krishnan, Brian D Robertson, Nick Platt, Gerald Larrouy-Maumus, Frances Mary Platt
Inhibition of the Niemann-Pick C1 protein is a conserved feature of multiple strains of pathogenic mycobacteria. Nature communications 13 (1) (2022)
Kerri-Lee Wallom, María E Fernández-Suárez, David A Priestman, Danielle Te Vruchte, Mylene Huebecker, Penelope J Hallett, Ole Isacson, Frances Mary Platt
Glycosphingolipid metabolism and its role in ageing and Parkinson's disease. Glycoconjugate journal (2021)
Ecem Kaya, David A Smith, Claire Smith, Barry Boland, Michael Strupp, Frances Mary Platt
Beneficial Effects of Acetyl-DL-Leucine (ADLL) in a Mouse Model of Sandhoff Disease. Journal of clinical medicine 9 (4) (2020)
Ecem Kaya, David A Smith, Claire Smith, Lauren Morris, Tatiana Bremova-Ertl, Mario Cortina-Borja, Paul Fineran, Karl J Morten, Joanna Poulton, Barry Boland, John Spencer, Michael Strupp, Frances Mary Platt
Acetyl-leucine slows disease progression in lysosomal storage disorders. Brain communications 3 (1) (2020)
Benita Claire Percival, Miles Gibson, Philippe Barrie Wilson, Frances Mary Platt, Martin Grootveld
Metabolomic Studies of Lipid Storage Disorders, with Special Reference to Niemann-Pick Type C Disease: A Critical Review with Future Perspectives. International journal of molecular sciences 21 (7) (2020)
Jorge L Rodriguez-Gil, Dawn E Watkins-Chow, Laura L Baxter, Gene Elliot, Ursula L Harper, Stephen M Wincovitch, Julia C Wedel, Arturo A Incao, Mylene Huebecker, Frederick J Boehm, William S Garver, Forbes D Porter, Karl W Broman, Frances Mary Platt, William J Pavan
Genetic background modifies phenotypic severity and longevity in a mouse model of Niemann-Pick disease type C1. Disease models & mechanisms 13 (3) (2020)
Grant C Churchill, Michael Leo Strupp, Antony Galione, Frances Mary Platt
Unexpected differences in the pharmacokinetics of N-acetyl-DL-leucine enantiomers after oral dosing and their clinical relevance. PloS one 15 (2) (2020)
Alexandria Colaco, María E Fernández-Suárez, Dawn Shepherd, Lihi Gal, Chen Bibi, Silvia Chuartzman, Alan Diot, Karl Morten, Emily R Eden, Forbes D Porter, Joanna Poulton, Nick Platt, Maya Schuldiner, Frances Mary Platt
Unbiased yeast screens identify cellular pathways affected in Niemann-Pick disease type C. Life science alliance 3 (7) (2020)
Mylene Huebecker, Elizabeth B Moloney, Aarnoud C van der Spoel, David A Priestman, Ole Isacson, Penelope J Hallett, Frances Mary Platt
Reduced sphingolipid hydrolase activities, substrate accumulation and ganglioside decline in Parkinson's disease. Molecular neurodegeneration 14 (1) (2019)
Julia Baguña Torres, Zilin Yu, Jayanta Bordoloi, Kavitha Sunassee, David Smith, Claire Smith, Oscar Chen, Rupert Purchase, Karin Tuschl, John Spencer, Frances Mary Platt, Philip J Blower
Imaging of changes in copper trafficking and redistribution in a mouse model of Niemann-Pick C disease using positron emission tomography. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 32 (2) (2019)
Christophe Paget, Shenglou Deng, Daphnée Soulard, David A Priestman, Silvia Speca, Johanna von Gerichten, Anneliese O Speak, Ashish Saroha, Yael Pewzner-Jung, Anthony H Futerman, Thierry Mallevaey, Christelle Faveeuw, Xiaobo Gu, Frances Mary Platt, Roger Sandhoff, François Trottein
TLR9-mediated dendritic cell activation uncovers mammalian ganglioside species with specific ceramide backbones that activate invariant natural killer T cells. PLoS biology 17 (3) (2019)
Alexandria Colaco, Ecem Kaya, Elias Adriaenssens, Lianne C Davis, Stefania Zampieri, María E Fernández-Suárez, Chong Y Tan, Patrick B Deegan, Forbes D Porter, Antony Galione, Bruno Bembi, Andrea Dardis, Frances Mary Platt
Mechanistic convergence and shared therapeutic targets in Niemann-Pick disease. Journal of inherited metabolic disease 43 (3) (2019)
Jose Miguel Gascon, Valentina Oliveri, Andrew McGown, Ecem Kaya, Yu-Lin Chen, Carol Austin, Martin Walker, Frances Mary Platt, Graziella Vecchio, John Spencer
Synthesis and Study of Multifunctional Cyclodextrin-Deferasirox Hybrids. ChemMedChem 14 (16) (2019)
Jakob Cervin, Amberlyn M Wands, Anna Casselbrant, Han Wu, Soumya Krishnamurthy, Aleksander Cvjetkovic, Johanna Estelius, Benjamin Dedic, Anirudh Sethi, Kerri-Lee Wallom, Rebecca Riise, Malin Bäckström, Ville Wallenius, Frances Mary Platt, Michael Lebens, Susann Teneberg, Lars Fändriks, Jennifer J Kohler, Ulf Yrlid
GM1 ganglioside-independent intoxication by Cholera toxin. PLoS pathogens 14 (2) (2018)
Mario Cortina-Borja, Danielle Te Vruchte, Eugen Mengel, Yasmin Amraoui, Jackie Imrie, Simon A Jones, Christine I Dali, Paul Fineran, Thomas Kirkegaard, Heiko Runz, Robin Lachmann, Tatiana Bremova-Ertl, Michael Strupp, Frances Mary Platt
Annual severity increment score as a tool for stratifying patients with Niemann-Pick disease type C and for recruitment to clinical trials. Orphanet journal of rare diseases 13 (1) (2018)
Elena-Raluca Nicoli, Mylene Huebecker, David A Smith, Lauren Morris, Frances Mary Platt
Differential response of the liver to bile acid treatment in a mouse model of Niemann-Pick disease type C. Wellcome open research 2 (2017)
William R H Evans, Elena-Raluca Nicoli, Raymond Yu-Jeang Wang, Nina Movsesyan, Frances Mary Platt
Case Report: Ursodeoxycholic acid treatment in Niemann-Pick disease type C; clinical experience in four cases. Wellcome open research 2 (2017)
Paul Fineran, Emyr Lloyd-Evans, Nathan A Lack, Nick Platt, Lianne C Davis, Anthony J Morgan, Doris Höglinger, Raju Venkata V Tatituri, Simon Clark, Ian M Williams, Patricia Tynan, Nada Al Eisa, Evgeniya Nazarova, Ann Williams, Antony Galione, Daniel S Ory, Gurdyal S Besra, David G Russell, Michael B Brenner, Edith Sim, Frances Mary Platt
Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway. Wellcome open research 1 (2016)
Frances Mary Platt, Michael Strupp
An anecdotal report by an Oxford basic neuroscientist: effects of acetyl-DL-leucine on cognitive function and mobility in the elderly. Journal of neurology 263 (6) (2016)

Frances Mary Platt.css-eqlu8i{font-size:small;padding-left:4px;} (Frances Platt, Frances M Platt)

Publication Activity (10 Years)

Top Topics

Top Venues

Frances Mary Platt (Frances Platt, Frances M Platt)