Francesc Xavier Ruiz (Francesc X Ruiz)

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 25

Top Topics

Structural Basis

Acinetobacter Baumannii

Top Venues

Journal of medicinal chemistry

Science advances

Science (New York, N.Y.)

This page only lists publications with an associated author ORCID identifier.

Publications

Bin Tan, Xiaoming Zhang, Ahmadullah Ansari, Prakash Jadhav, Haozhou Tan, Kan Li, Ashima Chopra, Alexandra Ford, Xiang Chi, Francesc Xavier Ruiz, Eddy Arnold, Xufang Deng, Jun Wang
Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model. Science (New York, N.Y.) 383 (6690) (2024)
Bin Tan, Xiaoming Zhang, Ahmadullah Ansari, Prakash Jadhav, Haozhou Tan, Kan Li, Ashima Chopra, Alexandra Ford, Xiang Chi, Francesc Xavier Ruiz, Eddy Arnold, Xufang Deng, Jun Wang
Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model. Science (New York, N.Y.) 383 (6690) (2024)
Bin Tan, Xiaoming Zhang, Ahmadullah Ansari, Prakash Jadhav, Haozhou Tan, Kan Li, Ashima Chopra, Alexandra Ford, Xiang Chi, Francesc Xavier Ruiz, Eddy Arnold, Xufang Deng, Jun Wang
Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model. Science (New York, N.Y.) 383 (6690) (2024)
Bin Tan, Xiaoming Zhang, Ahmadullah Ansari, Prakash Jadhav, Haozhou Tan, Kan Li, Ashima Chopra, Alexandra Ford, Xiang Chi, Francesc Xavier Ruiz, Eddy Arnold, Xufang Deng, Jun Wang
Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model. Science (New York, N.Y.) 383 (6690) (2024)
Eric T Baldwin, Trevor Van Eeuwen, David Hoyos, Arthur O Zalevsky, Egor P Tchesnokov, Roberto Sánchez, Bryant D Miller, Luciano H Di Stefano, Francesc Xavier Ruiz, Matthew Hancock, Esin Işik, Carlos Mendez-Dorantes, Thomas Walpole, Charles Nichols, Paul Wan, Kirsi Riento, Rowan Halls-Kass, Martin Augustin, Alfred Lammens, Anja Jestel, Paula Upla, Kera Xibinaku, Samantha Congreve, Maximiliaan Hennink, Kacper B Rogala, Anna M Schneider, Jennifer E Fairman, Shawn M Christensen, Brian Desrosiers, Gregory S Bisacchi, Oliver L Saunders, Nafeeza Hafeez, Wenyan Miao, Rosana Kapeller, Dennis M Zaller, Andrej Sali, Oliver Weichenrieder, Kathleen H Burns, Matthias Götte, Michael P Rout, Eddy Arnold, Benjamin D Greenbaum, Donna L Romero, John LaCava, Martin S Taylor
Structures, functions and adaptations of the human LINE-1 ORF2 protein. Nature 626 (7997) (2023)
Eric T Baldwin, Trevor Van Eeuwen, David Hoyos, Arthur O Zalevsky, Egor P Tchesnokov, Roberto Sánchez, Bryant D Miller, Luciano H Di Stefano, Francesc Xavier Ruiz, Matthew Hancock, Esin Işik, Carlos Mendez-Dorantes, Thomas Walpole, Charles Nichols, Paul Wan, Kirsi Riento, Rowan Halls-Kass, Martin Augustin, Alfred Lammens, Anja Jestel, Paula Upla, Kera Xibinaku, Samantha Congreve, Maximiliaan Hennink, Kacper B Rogala, Anna M Schneider, Jennifer E Fairman, Shawn M Christensen, Brian Desrosiers, Gregory S Bisacchi, Oliver L Saunders, Nafeeza Hafeez, Wenyan Miao, Rosana Kapeller, Dennis M Zaller, Andrej Sali, Oliver Weichenrieder, Kathleen H Burns, Matthias Götte, Michael P Rout, Eddy Arnold, Benjamin D Greenbaum, Donna L Romero, John LaCava, Martin S Taylor
Structures, functions, and adaptations of the human LINE-1 ORF2 protein. Nature (2023)
Eric T Baldwin, Trevor Van Eeuwen, David Hoyos, Arthur O Zalevsky, Egor P Tchesnokov, Roberto Sánchez, Bryant D Miller, Luciano H Di Stefano, Francesc Xavier Ruiz, Matthew Hancock, Esin Işik, Carlos Mendez-Dorantes, Thomas Walpole, Charles Nichols, Paul Wan, Kirsi Riento, Rowan Halls-Kass, Martin Augustin, Alfred Lammens, Anja Jestel, Paula Upla, Kera Xibinaku, Samantha Congreve, Maximiliaan Hennink, Kacper B Rogala, Anna M Schneider, Jennifer E Fairman, Shawn M Christensen, Brian Desrosiers, Gregory S Bisacchi, Oliver L Saunders, Nafeeza Hafeez, Wenyan Miao, Rosana Kapeller, Dennis M Zaller, Andrej Sali, Oliver Weichenrieder, Kathleen H Burns, Matthias Götte, Michael P Rout, Eddy Arnold, Benjamin D Greenbaum, Donna L Romero, John LaCava, Martin S Taylor
Structures, functions and adaptations of the human LINE-1 ORF2 protein. Nature (2023)
Eric T Baldwin, Trevor Van Eeuwen, David Hoyos, Arthur O Zalevsky, Egor P Tchesnokov, Roberto Sánchez, Bryant D Miller, Luciano H Di Stefano, Francesc Xavier Ruiz, Matthew Hancock, Esin Işik, Carlos Mendez-Dorantes, Thomas Walpole, Charles Nichols, Paul Wan, Kirsi Riento, Rowan Halls-Kass, Martin Augustin, Alfred Lammens, Anja Jestel, Paula Upla, Kera Xibinaku, Samantha Congreve, Maximiliaan Hennink, Kacper B Rogala, Anna M Schneider, Jennifer E Fairman, Shawn M Christensen, Brian Desrosiers, Gregory S Bisacchi, Oliver L Saunders, Nafeeza Hafeez, Wenyan Miao, Rosana Kapeller, Dennis M Zaller, Andrej Sali, Oliver Weichenrieder, Kathleen H Burns, Matthias Götte, Michael P Rout, Eddy Arnold, Benjamin D Greenbaum, Donna L Romero, John LaCava, Martin S Taylor
Structures, functions and adaptations of the human LINE-1 ORF2 protein. Nature 626 (7997) (2023)
Eric T Baldwin, Trevor Van Eeuwen, David Hoyos, Arthur O Zalevsky, Egor P Tchesnokov, Roberto Sánchez, Bryant D Miller, Luciano H Di Stefano, Francesc Xavier Ruiz, Matthew Hancock, Esin Işik, Carlos Mendez-Dorantes, Thomas Walpole, Charles Nichols, Paul Wan, Kirsi Riento, Rowan Halls-Kass, Martin Augustin, Alfred Lammens, Anja Jestel, Paula Upla, Kera Xibinaku, Samantha Congreve, Maximiliaan Hennink, Kacper B Rogala, Anna M Schneider, Jennifer E Fairman, Shawn M Christensen, Brian Desrosiers, Gregory S Bisacchi, Oliver L Saunders, Nafeeza Hafeez, Wenyan Miao, Rosana Kapeller, Dennis M Zaller, Andrej Sali, Oliver Weichenrieder, Kathleen H Burns, Matthias Götte, Michael P Rout, Eddy Arnold, Benjamin D Greenbaum, Donna L Romero, John LaCava, Martin S Taylor
Structures, functions and adaptations of the human LINE-1 ORF2 protein. Nature 626 (7997) (2023)
Ashima Chopra, Joseph D Bauman, Francesc Xavier Ruiz, Eddy Arnold
Halo Library, a Tool for Rapid Identification of Ligand Binding Sites on Proteins Using Crystallographic Fragment Screening. Journal of medicinal chemistry (2023)
Ashima Chopra, Joseph D Bauman, Francesc Xavier Ruiz, Eddy Arnold
Halo Library, a Tool for Rapid Identification of Ligand Binding Sites on Proteins Using Crystallographic Fragment Screening. Journal of medicinal chemistry 66 (9) (2023)
Ashima Chopra, Joseph D Bauman, Francesc Xavier Ruiz, Eddy Arnold
Halo Library, a Tool for Rapid Identification of Ligand Binding Sites on Proteins Using Crystallographic Fragment Screening. Journal of medicinal chemistry 66 (9) (2023)
Eric T Baldwin, Trevor Van Eeuwen, David Hoyos, Arthur O Zalevsky, Egor P Tchesnokov, Roberto Sánchez, Bryant D Miller, Luciano H Di Stefano, Francesc Xavier Ruiz, Matthew Hancock, Esin Işik, Carlos Mendez-Dorantes, Thomas Walpole, Charles Nichols, Paul Wan, Kirsi Riento, Rowan Halls-Kass, Martin Augustin, Alfred Lammens, Anja Jestel, Paula Upla, Kera Xibinaku, Samantha Congreve, Maximiliaan Hennink, Kacper B Rogala, Anna M Schneider, Jennifer E Fairman, Shawn M Christensen, Brian Desrosiers, Gregory S Bisacchi, Oliver L Saunders, Nafeeza Hafeez, Wenyan Miao, Rosana Kapeller, Dennis M Zaller, Andrej Sali, Oliver Weichenrieder, Kathleen H Burns, Matthias Götte, Michael P Rout, Eddy Arnold, Benjamin D Greenbaum, Donna L Romero, John LaCava, Martin S Taylor
Structures, functions and adaptations of the human LINE-1 ORF2 protein. Nature 626 (7997) (2023)
Mahta Mansouri, Shawn Rumrill, Shane Dawson, Adam Johnson, Jo-Anne Pinson, Menachem J Gunzburg, Catherine F Latham, Nicholas Barlow, George W Mbogo, Paula Ellenberg, Stephen J Headey, Nicolas Sluis-Cremer, David Tyssen, Joseph D Bauman, Francesc Xavier Ruiz, Eddy Arnold, David K Chalmers, Gilda Tachedjian
Targeting HIV-1 Reverse Transcriptase Using a Fragment-Based Approach. Molecules (Basel, Switzerland) 28 (7) (2023)
Eric T Baldwin, Trevor Van Eeuwen, David Hoyos, Arthur O Zalevsky, Egor P Tchesnokov, Roberto Sánchez, Bryant D Miller, Luciano H Di Stefano, Francesc Xavier Ruiz, Matthew Hancock, Esin Işik, Carlos Mendez-Dorantes, Thomas Walpole, Charles Nichols, Paul Wan, Kirsi Riento, Rowan Halls-Kass, Martin Augustin, Alfred Lammens, Anja Jestel, Paula Upla, Kera Xibinaku, Samantha Congreve, Maximiliaan Hennink, Kacper B Rogala, Anna M Schneider, Jennifer E Fairman, Shawn M Christensen, Brian Desrosiers, Gregory S Bisacchi, Oliver L Saunders, Nafeeza Hafeez, Wenyan Miao, Rosana Kapeller, Dennis M Zaller, Andrej Sali, Oliver Weichenrieder, Kathleen H Burns, Matthias Götte, Michael P Rout, Eddy Arnold, Benjamin D Greenbaum, Donna L Romero, John LaCava, Martin S Taylor
Structures, functions and adaptations of the human LINE-1 ORF2 protein. Nature (2023)
Eric T Baldwin, Trevor Van Eeuwen, David Hoyos, Arthur O Zalevsky, Egor P Tchesnokov, Roberto Sánchez, Bryant D Miller, Luciano H Di Stefano, Francesc Xavier Ruiz, Matthew Hancock, Esin Işik, Carlos Mendez-Dorantes, Thomas Walpole, Charles Nichols, Paul Wan, Kirsi Riento, Rowan Halls-Kass, Martin Augustin, Alfred Lammens, Anja Jestel, Paula Upla, Kera Xibinaku, Samantha Congreve, Maximiliaan Hennink, Kacper B Rogala, Anna M Schneider, Jennifer E Fairman, Shawn M Christensen, Brian Desrosiers, Gregory S Bisacchi, Oliver L Saunders, Nafeeza Hafeez, Wenyan Miao, Rosana Kapeller, Dennis M Zaller, Andrej Sali, Oliver Weichenrieder, Kathleen H Burns, Matthias Götte, Michael P Rout, Eddy Arnold, Benjamin D Greenbaum, Donna L Romero, John LaCava, Martin S Taylor
Structures, functions, and adaptations of the human LINE-1 ORF2 protein. Nature (2023)
Ashima Chopra, Joseph D Bauman, Francesc Xavier Ruiz, Eddy Arnold
Halo Library, a Tool for Rapid Identification of Ligand Binding Sites on Proteins Using Crystallographic Fragment Screening. Journal of medicinal chemistry 66 (9) (2023)
Eric T Baldwin, Trevor Van Eeuwen, David Hoyos, Arthur O Zalevsky, Egor P Tchesnokov, Roberto Sánchez, Bryant D Miller, Luciano H Di Stefano, Francesc Xavier Ruiz, Matthew Hancock, Esin Işik, Carlos Mendez-Dorantes, Thomas Walpole, Charles Nichols, Paul Wan, Kirsi Riento, Rowan Halls-Kass, Martin Augustin, Alfred Lammens, Anja Jestel, Paula Upla, Kera Xibinaku, Samantha Congreve, Maximiliaan Hennink, Kacper B Rogala, Anna M Schneider, Jennifer E Fairman, Shawn M Christensen, Brian Desrosiers, Gregory S Bisacchi, Oliver L Saunders, Nafeeza Hafeez, Wenyan Miao, Rosana Kapeller, Dennis M Zaller, Andrej Sali, Oliver Weichenrieder, Kathleen H Burns, Matthias Götte, Michael P Rout, Eddy Arnold, Benjamin D Greenbaum, Donna L Romero, John LaCava, Martin S Taylor
Structures, functions and adaptations of the human LINE-1 ORF2 protein. Nature (2023)
Eric T Baldwin, Trevor Van Eeuwen, David Hoyos, Arthur O Zalevsky, Egor P Tchesnokov, Roberto Sánchez, Bryant D Miller, Luciano H Di Stefano, Francesc Xavier Ruiz, Matthew Hancock, Esin Işik, Carlos Mendez-Dorantes, Thomas Walpole, Charles Nichols, Paul Wan, Kirsi Riento, Rowan Halls-Kass, Martin Augustin, Alfred Lammens, Anja Jestel, Paula Upla, Kera Xibinaku, Samantha Congreve, Maximiliaan Hennink, Kacper B Rogala, Anna M Schneider, Jennifer E Fairman, Shawn M Christensen, Brian Desrosiers, Gregory S Bisacchi, Oliver L Saunders, Nafeeza Hafeez, Wenyan Miao, Rosana Kapeller, Dennis M Zaller, Andrej Sali, Oliver Weichenrieder, Kathleen H Burns, Matthias Götte, Michael P Rout, Eddy Arnold, Benjamin D Greenbaum, Donna L Romero, John LaCava, Martin S Taylor
Structures, functions and adaptations of the human LINE-1 ORF2 protein. Nature 626 (7997) (2023)
Ashima Chopra, Joseph D Bauman, Francesc Xavier Ruiz, Eddy Arnold
Halo Library, a Tool for Rapid Identification of Ligand Binding Sites on Proteins Using Crystallographic Fragment Screening. Journal of medicinal chemistry 66 (9) (2023)
Jerry Joe E K Harrison, Dario Oliveira Passos, Jessica F Bruhn, Joseph D Bauman, Lynda Tuberty, Jeffrey J DeStefano, Francesc Xavier Ruiz, Dmitry Lyumkis, Eddy Arnold
Cryo-EM structure of the HIV-1 Pol polyprotein provides insights into virion maturation. Science advances 8 (27) (2022)
Ruchi Yadav, Valentine V Courouble, Sanjay Kumar Dey, Jerry Joe E K Harrison, Jennifer Timm, Jesse B Hopkins, Ryan L Slack, Stefan G Sarafianos, Francesc Xavier Ruiz, Patrick R Griffin, Eddy Arnold
Biochemical and structural insights into SARS-CoV-2 polyprotein processing by Mpro. Science advances 8 (49) (2022)
Ruchi Yadav, Valentine V Courouble, Sanjay Kumar Dey, Jerry Joe E K Harrison, Jennifer Timm, Jesse B Hopkins, Ryan L Slack, Stefan G Sarafianos, Francesc Xavier Ruiz, Patrick R Griffin, Eddy Arnold
Biochemical and structural insights into SARS-CoV-2 polyprotein processing by Mpro. Science advances 8 (49) (2022)
Ruchi Yadav, Valentine V Courouble, Sanjay Kumar Dey, Jerry Joe E K Harrison, Jennifer Timm, Jesse B Hopkins, Ryan L Slack, Stefan G Sarafianos, Francesc Xavier Ruiz, Patrick R Griffin, Eddy Arnold
Biochemical and structural insights into SARS-CoV-2 polyprotein processing by Mpro. Science advances 8 (49) (2022)
Francesc Xavier Ruiz, Xavier Parés, Jaume Farrés
Perspective on the Structural Basis for Human Aldo-Keto Reductase 1B10 Inhibition. Metabolites 11 (12) (2021)