Graeme L Conn

ORCID

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 22

Top Venues

Antimicrobial agents and chemotherapy

bioRxiv : the preprint server for biology

The Journal of biological chemistry

Proceedings of the National Academy of Sciences of the United States of America

Emory University School of Medicine

University of Edinburgh (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Emory University School of Medicine Aug 01 2019

United States

Professor :: Biochemistry

Emory University School of Medicine Sep 15 2008 - Aug 31 2019

United States

Associate Professor :: Biochemistry

University of Manchester Oct 01 2004 - Aug 31 2008

United Kingdom

Lecturer/ Senior Lecturer :: Faculty of Life Sciences

UMIST Jan 01 2000 - Sep 30 2004

United Kingdom

Wellcome Trust CDF/ Lecturer :: Biomolecular Sciences

Johns Hopkins University Nov 15 1996 - Nov 30 1999

United States

Postdoctoral Fellow :: Chemistry

Education History

University of Edinburgh

United Kingdom

PHD :: Chemistry

Publications

William M Shafer, Graeme L Conn
Ensuring a sustained workforce to combat antibiotic resistance in the 21st century: the critical need for training the next-gen of scientists at the pre-doctoral level. Antimicrobial agents and chemotherapy (2024)
Logan G Kavanaugh, Debayan Dey, William M Shafer, Graeme L Conn
Structural and functional diversity of Resistance-Nodulation-Division (RND) efflux pump transporters with implications for antimicrobial resistance. Microbiology and molecular biology reviews : MMBR (2024)
William M Shafer, Graeme L Conn
Ensuring a sustained workforce to combat antibiotic resistance in the 21st century: the critical need for training the next-gen of scientists at the pre-doctoral level. Antimicrobial agents and chemotherapy (2024)
Learnmore Jeremia, Benjamin E Deprez, Debayan Dey, Graeme L Conn, William M Wuest
Ribosome-targeting antibiotics and resistance via ribosomal RNA methylation. RSC medicinal chemistry 14 (4) (2023)
Sarah E Strassler, Isobel E Bowles, Aiswarya Krishnamohan, Hyejeong Kim, Emily G Kuiper, Lindsay R Comstock, Jane E Jackman, Graeme L Conn
tRNA m 1 G9 modification depends on substrate-specific RNA conformational changes induced by the methyltransferase Trm10. bioRxiv : the preprint server for biology (2023)
Logan G Kavanaugh, Andrew R Mahoney, Debayan Dey, William M Wuest, Graeme L Conn
Di-berberine conjugates as chemical probes of Pseudomonas aeruginosa MexXY-OprM efflux function and inhibition. bioRxiv : the preprint server for biology (2023)
Learnmore Jeremia, Benjamin E Deprez, Debayan Dey, Graeme L Conn, William M Wuest
Ribosome-targeting antibiotics and resistance via ribosomal RNA methylation. RSC medicinal chemistry 14 (4) (2023)
Sarah E Strassler, Isobel E Bowles, Aiswarya Krishnamohan, Hyejeong Kim, Emily G Kuiper, Lindsay R Comstock, Jane E Jackman, Graeme L Conn
tRNA m 1 G9 modification depends on substrate-specific RNA conformational changes induced by the methyltransferase Trm10. bioRxiv : the preprint server for biology (2023)
Pooja Srinivas, Meisam Nosrati, Natalia Zelinskaya, Debayan Dey, Lindsay R Comstock, Christine M Dunham, Graeme L Conn
30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC. bioRxiv : the preprint server for biology (2023)
Pooja Srinivas, Meisam Nosrati, Natalia Zelinskaya, Debayan Dey, Lindsay R Comstock, Christine M Dunham, Graeme L Conn
30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC. Proceedings of the National Academy of Sciences of the United States of America 120 (25) (2023)
Zane T Laughlin, Suparno Nandi, Debayan Dey, Natalia Zelinskaya, Marta A Witek, Pooja Srinivas, Ha An Nguyen, Emily G Kuiper, Lindsay R Comstock, Christine M Dunham, Graeme L Conn
50S subunit recognition and modification by the Mycobacterium tuberculosis ribosomal RNA methyltransferase TlyA. Proceedings of the National Academy of Sciences of the United States of America 119 (14) (2022)
Samantha L Schwartz, Debayan Dey, Julia Tanquary, Camden R Bair, Anice C Lowen, Graeme L Conn
Role of helical structure and dynamics in oligoadenylate synthetase 1 (OAS1) mismatch tolerance and activation by short dsRNAs. Proceedings of the National Academy of Sciences of the United States of America 119 (3) (2022)
Thomas Magg, Tsubasa Okano, Lars M Koenig, Daniel F R Boehmer, Samantha L Schwartz, Kento Inoue, Jennifer Heimall, Francesco Licciardi, Julia Ley-Zaporozhan, Ronald M Ferdman, Andrés Caballero Garcia de Oteyza, Esther N Park, Brenda M Calderon, Debayan Dey, Hirokazu Kanegane, Kazutoshi Cho, Davide Montin, Karl Reiter, Matthias Griese, Michael H Albert, Meino Rohlfs, Paul Gray, Christoph Walz, Graeme L Conn, Kathleen E Sullivan, Christoph Klein, Tomohiro Morio, Fabian H Hauck
Heterozygous OAS1 gain-of-function variants cause an autoinflammatory immunodeficiency. Science immunology 6 (60) (2022)
Debayan Dey, Suryanarayanarao Ramakumar, Graeme L Conn
Targeted Redesign of Suramin Analogs for Novel Antimicrobial Lead Development. Journal of chemical information and modeling 61 (9) (2021)
Debayan Dey, Logan G Kavanaugh, Graeme L Conn
Antibiotic Substrate Selectivity of Pseudomonas aeruginosa MexY and MexB Efflux Systems Is Determined by a Goldilocks Affinity. Antimicrobial agents and chemotherapy 64 (8) (2020)
Brenda M Calderon, Shamika Danzy, Gabrielle K Delima, Nathan T Jacobs, Ketaki Ganti, Megan R Hockman, Graeme L Conn, Anice C Lowen, John Steel
Dysregulation of M segment gene expression contributes to influenza A virus host restriction. PLoS pathogens 15 (8) (2019)
Meisam Nosrati, Debayan Dey, Atousa Mehrani, Sarah E Strassler, Natalia Zelinskaya, Eric D Hoffer, Scott M Stagg, Christine M Dunham, Graeme L Conn
Functionally critical residues in the aminoglycoside resistance-associated methyltransferase RmtC play distinct roles in 30S substrate recognition. The Journal of biological chemistry 294 (46) (2019)
Samantha M Prezioso, Duc M Duong, Emily G Kuiper, Qiudong Deng, Sebastián Albertí, Graeme L Conn, Joanna B Goldberg
Trimethylation of Elongation Factor-Tu by the Dual Thermoregulated Methyltransferase EftM Does Not Impact Its Canonical Function in Translation. Scientific reports 9 (1) (2019)
Emily G Kuiper, Debayan Dey, Paige A LaMore, Joshua P Owings, Samantha M Prezioso, Joanna B Goldberg, Graeme L Conn
Substrate recognition by the Pseudomonas aeruginosa EF-Tu-modifying methyltransferase EftM. The Journal of biological chemistry 294 (52) (2019)
Brenda M Calderon, Graeme L Conn
A human cellular noncoding RNA activates the antiviral protein 2'-5'-oligoadenylate synthetase 1. The Journal of biological chemistry 293 (41) (2018)
Brenda M Calderon, Graeme L Conn
Human noncoding RNA 886 (nc886) adopts two structurally distinct conformers that are functionally opposing regulators of PKR. RNA (New York, N.Y.) 23 (4) (2017)
Kellie Vinal, Graeme L Conn
Substrate Recognition and Modification by a Pathogen-Associated Aminoglycoside Resistance 16S rRNA Methyltransferase. Antimicrobial agents and chemotherapy 61 (5) (2017)
Laís L Corrêa, Marta A Witek, Natalia Zelinskaya, Renata C Picão, Graeme L Conn
Heterologous Expression and Functional Characterization of the Exogenously Acquired Aminoglycoside Resistance Methyltransferases RmtD, RmtD2, and RmtG. Antimicrobial agents and chemotherapy 60 (1) (2015)
Natalia Zelinskaya, Marta A Witek, Graeme L Conn
The Pathogen-Derived Aminoglycoside Resistance 16S rRNA Methyltransferase NpmA Possesses Dual m1A1408/m1G1408 Specificity. Antimicrobial agents and chemotherapy 59 (12) (2015)
Miloje Savic, S Sunita, Natalia Zelinskaya, Pooja M Desai, Rachel Macmaster, Kellie Vinal, Graeme L Conn
30S Subunit-dependent activation of the Sorangium cellulosum So ce56 aminoglycoside resistance-conferring 16S rRNA methyltransferase Kmr. Antimicrobial agents and chemotherapy 59 (5) (2015)
Marta A Witek, Graeme L Conn
Functional dichotomy in the 16S rRNA (m1A1408) methyltransferase family and control of catalytic activity via a novel tryptophan mediated loop reorganization. Nucleic acids research 44 (1) (2015)
Virginia K Vachon, Brenda M Calderon, Graeme L Conn
A novel RNA molecular signature for activation of 2'-5' oligoadenylate synthetase-1. Nucleic acids research 43 (1) (2014)

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Publication Activity (10 Years)

Top Topics

Top Venues

Graeme L Conn