Haiming Zhang

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 32

Top Topics

Molecular Docking

Room Temperature

Capillary Electrophoresis

Top Venues

Journal of the American Chemical Society

Organic letters

The Journal of organic chemistry

Chemical science

This page only lists publications with an associated author ORCID identifier.

Publications

Brittany C Haas, Ngiap-Kie Lim, Janis Jermaks, Eden Gaster, Melody C Guo, Thomas C Malig, Jacob Werth, Haiming Zhang, F Dean Toste, Francis Gosselin, Scott J Miller, Matthew S Sigman
Enantioselective Sulfonimidamide Acylation via a Cinchona Alkaloid-Catalyzed Desymmetrization: Scope, Data Science, and Mechanistic Investigation. Journal of the American Chemical Society (2024)
Brittany C Haas, Ngiap-Kie Lim, Janis Jermaks, Eden Gaster, Melody C Guo, Thomas C Malig, Jacob Werth, Haiming Zhang, F Dean Toste, Francis Gosselin, Scott J Miller, Matthew S Sigman
Enantioselective Sulfonimidamide Acylation via a Cinchona Alkaloid-Catalyzed Desymmetrization: Scope, Data Science, and Mechanistic Investigation. Journal of the American Chemical Society 146 (12) (2024)
Brittany C Haas, Ngiap-Kie Lim, Janis Jermaks, Eden Gaster, Melody C Guo, Thomas C Malig, Jacob Werth, Haiming Zhang, F Dean Toste, Francis Gosselin, Scott J Miller, Matthew S Sigman
Enantioselective Sulfonimidamide Acylation via a Cinchona Alkaloid-Catalyzed Desymmetrization: Scope, Data Science, and Mechanistic Investigation. Journal of the American Chemical Society 146 (12) (2024)
Brittany C Haas, Ngiap-Kie Lim, Janis Jermaks, Eden Gaster, Melody C Guo, Thomas C Malig, Jacob Werth, Haiming Zhang, F Dean Toste, Francis Gosselin, Scott J Miller, Matthew S Sigman
Enantioselective Sulfonimidamide Acylation via a Cinchona Alkaloid-Catalyzed Desymmetrization: Scope, Data Science, and Mechanistic Investigation. Journal of the American Chemical Society 146 (12) (2024)
Brittany C Haas, Ngiap-Kie Lim, Janis Jermaks, Eden Gaster, Melody C Guo, Thomas C Malig, Jacob Werth, Haiming Zhang, F Dean Toste, Francis Gosselin, Scott J Miller, Matthew S Sigman
Enantioselective Sulfonimidamide Acylation via a Cinchona Alkaloid-Catalyzed Desymmetrization: Scope, Data Science, and Mechanistic Investigation. Journal of the American Chemical Society (2024)
Brittany C Haas, Ngiap-Kie Lim, Janis Jermaks, Eden Gaster, Melody C Guo, Thomas C Malig, Jacob Werth, Haiming Zhang, F Dean Toste, Francis Gosselin, Scott J Miller, Matthew S Sigman
Enantioselective Sulfonimidamide Acylation via a Cinchona Alkaloid-Catalyzed Desymmetrization: Scope, Data Science, and Mechanistic Investigation. Journal of the American Chemical Society 146 (12) (2024)
Jie Xu, Ngiap-Kie Lim, Jacob C Timmerman, Jeff Shen, Kyle Clagg, Ugo Orcel, Raphael Bigler, Etienne Trachsel, Roland Meier, Nicholas A White, Johannes A Burkhard, Lauren E Sirois, Qingping Tian, Remy Angelaud, Stephan Bachmann, Haiming Zhang, Francis Gosselin
Second-Generation Atroposelective Synthesis of KRAS G12C Covalent Inhibitor GDC-6036. Organic letters 25 (19) (2023)
Jie Xu, Ngiap-Kie Lim, Jacob C Timmerman, Jeff Shen, Kyle Clagg, Ugo Orcel, Raphael Bigler, Etienne Trachsel, Roland Meier, Nicholas A White, Johannes A Burkhard, Lauren E Sirois, Qingping Tian, Remy Angelaud, Stephan Bachmann, Haiming Zhang, Francis Gosselin
Second-Generation Atroposelective Synthesis of KRAS G12C Covalent Inhibitor GDC-6036. Organic letters (2023)
Lucy van Dijk, Brittany C Haas, Ngiap-Kie Lim, Kyle Clagg, Jordan J Dotson, Sean M Treacy, Katarzyna A Piechowicz, Vladislav A Roytman, Haiming Zhang, F Dean Toste, Scott J Miller, Francis Gosselin, Matthew S Sigman
Data Science-Enabled Palladium-Catalyzed Enantioselective Aryl-Carbonylation of Sulfonimidamides. Journal of the American Chemical Society (2023)
Jie Xu, Ngiap-Kie Lim, Jacob C Timmerman, Jeff Shen, Kyle Clagg, Ugo Orcel, Raphael Bigler, Etienne Trachsel, Roland Meier, Nicholas A White, Johannes A Burkhard, Lauren E Sirois, Qingping Tian, Remy Angelaud, Stephan Bachmann, Haiming Zhang, Francis Gosselin
Second-Generation Atroposelective Synthesis of KRAS G12C Covalent Inhibitor GDC-6036. Organic letters 25 (19) (2023)
Brennan T Rose, Jacob C Timmerman, Seth A Bawel, Steven Chin, Haiming Zhang, Scott E Denmark
High-Level Data Fusion Enables the Chemoinformatically Guided Discovery of Chiral Disulfonimide Catalysts for Atropselective Iodination of 2-Amino-6-arylpyridines. Journal of the American Chemical Society 144 (50) (2022)
Jie Xu, Samantha Grosslight, Kyle A Mack, Sierra C Nguyen, Kyle Clagg, Ngiap-Kie Lim, Jacob C Timmerman, Jeff Shen, Nicholas A White, Lauren E Sirois, Chong Han, Haiming Zhang, Matthew S Sigman, Francis Gosselin
Atroposelective Negishi Coupling Optimization Guided by Multivariate Linear Regression Analysis: Asymmetric Synthesis of KRAS G12C Covalent Inhibitor GDC-6036. Journal of the American Chemical Society 144 (45) (2022)
Brennan T Rose, Jacob C Timmerman, Seth A Bawel, Steven Chin, Haiming Zhang, Scott E Denmark
High-Level Data Fusion Enables the Chemoinformatically Guided Discovery of Chiral Disulfonimide Catalysts for Atropselective Iodination of 2-Amino-6-arylpyridines. Journal of the American Chemical Society 144 (50) (2022)
Daniel Zell, Cian Kingston, Janis Jermaks, Sleight R Smith, Natalie Seeger, Jana Wassmer, Lauren E Sirois, Chong Han, Haiming Zhang, Matthew S Sigman, Francis Gosselin
Stereoconvergent and -divergent Synthesis of Tetrasubstituted Alkenes by Nickel-Catalyzed Cross-Couplings. Journal of the American Chemical Society 143 (45) (2021)
Remi Lavernhe, Eric J Alexy, Haiming Zhang, Brian M Stoltz
Palladium-Catalyzed Enantioselective Decarboxylative Allylic Alkylation of Acyclic α-N-Pyrrolyl/Indolyl Ketones. Organic letters 22 (11) (2020)
Tyler J Fulton, Alexander Q Cusumano, Eric J Alexy, Yun E Du, Haiming Zhang, Kendall N Houk, Brian M Stoltz
Global Diastereoconvergence in the Ireland-Claisen Rearrangement of Isomeric Enolates: Synthesis of Tetrasubstituted α-Amino Acids. Journal of the American Chemical Society 142 (52) (2020)
Nicholas A White, Kyle Clagg, Lauren E Sirois, Kyle A Mack, Mohammad A Al-Sayah, William A Nack, Paul D O'Shea, Haiming Zhang, Francis Gosselin
Phosphoramidates as Steering Elements for Highly Selective Access to Complementary Imidazo[1,2-a]pyrimidine Isomers. Organic letters 21 (23) (2019)
Eric J Alexy, Tyler J Fulton, Haiming Zhang, Brian M Stoltz
Palladium-catalyzed enantioselective decarboxylative allylic alkylation of fully substituted N-acyl indole-derived enol carbonates. Chemical science 10 (23) (2019)
Ngiap-Kie Lim, Xin Linghu, Nicholas Wong, Haiming Zhang, C Gregory Sowell, Francis Gosselin
Macrolactamization Approaches to Arylomycin Antibiotics Core. Organic letters 21 (1) (2018)
Michael E Dalziel, Julie A Deichert, Diane E Carrera, Danial Beaudry, Chong Han, Haiming Zhang, Remy Angelaud
Magnesium Ethoxide Promoted Conversion of Nitriles to Amidines and Its Application in 5,6-Dihydroimidazobenzoxazepine Synthesis. Organic letters 20 (9) (2018)
Jens Wolfard, Jie Xu, Haiming Zhang, Cheol K Chung
Synthesis of Chiral Tryptamines via a Regioselective Indole Alkylation. Organic letters 20 (17) (2018)
Eric J Alexy, Haiming Zhang, Brian M Stoltz
Catalytic Enantioselective Synthesis of Acyclic Quaternary Centers: Palladium-Catalyzed Decarboxylative Allylic Alkylation of Fully Substituted Acyclic Enol Carbonates. Journal of the American Chemical Society 140 (32) (2018)
Haiming Zhang, Beryl X Li, Brian Wong, Andreas Stumpf, C Gregory Sowell, Francis Gosselin
Convergent Synthesis of PI3K Inhibitor GDC-0908 Featuring Palladium-Catalyzed Direct C-H Arylation toward Dihydrobenzothienooxepines. The Journal of organic chemistry 84 (8) (2018)
Cosme Sandoval, Ngiap-Kie Lim, Haiming Zhang
Two-Step Synthesis of 3,4-Dihydropyrrolopyrazinones from Ketones and Piperazin-2-ones. Organic letters 20 (4) (2018)
Scott Savage, Andrew McClory, Haiming Zhang, Theresa Cravillion, Ngiap-Kie Lim, Colin Masui, Sarah J Robinson, Chong Han, Christoph Ochs, Pankaj D Rege, Francis Gosselin
Synthesis of Selective Estrogen Receptor Degrader GDC-0810 via Stereocontrolled Assembly of a Tetrasubstituted All-Carbon Olefin. The Journal of organic chemistry 83 (19) (2018)
Ian S Young, Anna-Lena Glass, Theresa Cravillion, Chong Han, Haiming Zhang, Francis Gosselin
Palladium-Catalyzed Site-Selective Amidation of Dichloroazines. Organic letters 20 (13) (2018)
Ngiap-Kie Lim, Theresa Cravillion, Scott Savage, Andrew McClory, Chong Han, Haiming Zhang, Antonio DiPasquale, Francis Gosselin
Synthesis of a Selective Estrogen Receptor Degrader via a Stereospecific Elimination Approach. Organic letters 20 (4) (2018)
Michael E Dalziel, Penghao Chen, Diane E Carrera, Haiming Zhang, Francis Gosselin
Highly Diastereoselective α-Arylation of Cyclic Nitriles. Organic letters 19 (13) (2017)
Beryl X Li, Diane N Le, Kyle A Mack, Andrew McClory, Ngiap-Kie Lim, Theresa Cravillion, Scott Savage, Chong Han, David B Collum, Haiming Zhang, Francis Gosselin
Highly Stereoselective Synthesis of Tetrasubstituted Acyclic All-Carbon Olefins via Enol Tosylation and Suzuki-Miyaura Coupling. Journal of the American Chemical Society 139 (31) (2017)
Kyle A Mack, Andrew McClory, Haiming Zhang, Francis Gosselin, David B Collum
Lithium Hexamethyldisilazide-Mediated Enolization of Highly Substituted Aryl Ketones: Structural and Mechanistic Basis of the E/Z Selectivities. Journal of the American Chemical Society 139 (35) (2017)
Ngiap-Kie Lim, Patrick Weiss, Beryl X Li, Christina H McCulley, Stephanie R Hare, Bronwyn L Bensema, Teresa A Palazzo, Dean Joseph Tantillo, Haiming Zhang, Francis Gosselin
Synthesis of Highly Stereodefined Tetrasubstituted Acyclic All-Carbon Olefins via a Syn-Elimination Approach. Organic letters 19 (22) (2017)
Anthony Y Chen, Qianqian Lu, Yao Fu, Richmond Sarpong, Brian M Stoltz, Haiming Zhang
Isocanthine Synthesis via Rh(III)-Catalyzed Intramolecular C-H Functionalization. The Journal of organic chemistry 83 (1) (2017)