Ngiap-Kie Lim

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 13

Top Topics

Molecular Docking

Reduced Graphene Oxide

Structural Basis

Room Temperature

Top Venues

Journal of the American Chemical Society

Organic letters

This page only lists publications with an associated author ORCID identifier.

Publications

Brittany C Haas, Ngiap-Kie Lim, Janis Jermaks, Eden Gaster, Melody C Guo, Thomas C Malig, Jacob Werth, Haiming Zhang, F Dean Toste, Francis Gosselin, Scott J Miller, Matthew S Sigman
Enantioselective Sulfonimidamide Acylation via a Cinchona Alkaloid-Catalyzed Desymmetrization: Scope, Data Science, and Mechanistic Investigation. Journal of the American Chemical Society (2024)
Brittany C Haas, Ngiap-Kie Lim, Janis Jermaks, Eden Gaster, Melody C Guo, Thomas C Malig, Jacob Werth, Haiming Zhang, F Dean Toste, Francis Gosselin, Scott J Miller, Matthew S Sigman
Enantioselective Sulfonimidamide Acylation via a Cinchona Alkaloid-Catalyzed Desymmetrization: Scope, Data Science, and Mechanistic Investigation. Journal of the American Chemical Society 146 (12) (2024)
Brittany C Haas, Ngiap-Kie Lim, Janis Jermaks, Eden Gaster, Melody C Guo, Thomas C Malig, Jacob Werth, Haiming Zhang, F Dean Toste, Francis Gosselin, Scott J Miller, Matthew S Sigman
Enantioselective Sulfonimidamide Acylation via a Cinchona Alkaloid-Catalyzed Desymmetrization: Scope, Data Science, and Mechanistic Investigation. Journal of the American Chemical Society 146 (12) (2024)
Brittany C Haas, Ngiap-Kie Lim, Janis Jermaks, Eden Gaster, Melody C Guo, Thomas C Malig, Jacob Werth, Haiming Zhang, F Dean Toste, Francis Gosselin, Scott J Miller, Matthew S Sigman
Enantioselective Sulfonimidamide Acylation via a Cinchona Alkaloid-Catalyzed Desymmetrization: Scope, Data Science, and Mechanistic Investigation. Journal of the American Chemical Society 146 (12) (2024)
Brittany C Haas, Ngiap-Kie Lim, Janis Jermaks, Eden Gaster, Melody C Guo, Thomas C Malig, Jacob Werth, Haiming Zhang, F Dean Toste, Francis Gosselin, Scott J Miller, Matthew S Sigman
Enantioselective Sulfonimidamide Acylation via a Cinchona Alkaloid-Catalyzed Desymmetrization: Scope, Data Science, and Mechanistic Investigation. Journal of the American Chemical Society (2024)
Brittany C Haas, Ngiap-Kie Lim, Janis Jermaks, Eden Gaster, Melody C Guo, Thomas C Malig, Jacob Werth, Haiming Zhang, F Dean Toste, Francis Gosselin, Scott J Miller, Matthew S Sigman
Enantioselective Sulfonimidamide Acylation via a Cinchona Alkaloid-Catalyzed Desymmetrization: Scope, Data Science, and Mechanistic Investigation. Journal of the American Chemical Society 146 (12) (2024)
Jie Xu, Ngiap-Kie Lim, Jacob C Timmerman, Jeff Shen, Kyle Clagg, Ugo Orcel, Raphael Bigler, Etienne Trachsel, Roland Meier, Nicholas A White, Johannes A Burkhard, Lauren E Sirois, Qingping Tian, Remy Angelaud, Stephan Bachmann, Haiming Zhang, Francis Gosselin
Second-Generation Atroposelective Synthesis of KRAS G12C Covalent Inhibitor GDC-6036. Organic letters 25 (19) (2023)
Jie Xu, Ngiap-Kie Lim, Jacob C Timmerman, Jeff Shen, Kyle Clagg, Ugo Orcel, Raphael Bigler, Etienne Trachsel, Roland Meier, Nicholas A White, Johannes A Burkhard, Lauren E Sirois, Qingping Tian, Remy Angelaud, Stephan Bachmann, Haiming Zhang, Francis Gosselin
Second-Generation Atroposelective Synthesis of KRAS G12C Covalent Inhibitor GDC-6036. Organic letters (2023)
Lucy van Dijk, Brittany C Haas, Ngiap-Kie Lim, Kyle Clagg, Jordan J Dotson, Sean M Treacy, Katarzyna A Piechowicz, Vladislav A Roytman, Haiming Zhang, F Dean Toste, Scott J Miller, Francis Gosselin, Matthew S Sigman
Data Science-Enabled Palladium-Catalyzed Enantioselective Aryl-Carbonylation of Sulfonimidamides. Journal of the American Chemical Society (2023)
Jie Xu, Ngiap-Kie Lim, Jacob C Timmerman, Jeff Shen, Kyle Clagg, Ugo Orcel, Raphael Bigler, Etienne Trachsel, Roland Meier, Nicholas A White, Johannes A Burkhard, Lauren E Sirois, Qingping Tian, Remy Angelaud, Stephan Bachmann, Haiming Zhang, Francis Gosselin
Second-Generation Atroposelective Synthesis of KRAS G12C Covalent Inhibitor GDC-6036. Organic letters 25 (19) (2023)
Jie Xu, Samantha Grosslight, Kyle A Mack, Sierra C Nguyen, Kyle Clagg, Ngiap-Kie Lim, Jacob C Timmerman, Jeff Shen, Nicholas A White, Lauren E Sirois, Chong Han, Haiming Zhang, Matthew S Sigman, Francis Gosselin
Atroposelective Negishi Coupling Optimization Guided by Multivariate Linear Regression Analysis: Asymmetric Synthesis of KRAS G12C Covalent Inhibitor GDC-6036. Journal of the American Chemical Society 144 (45) (2022)
Nicholas Wong, Filip Petronijević, Allen Y Hong, Xin Linghu, Sean M Kelly, Haiyun Hou, Theresa Cravillion, Ngiap-Kie Lim, Sarah J Robinson, Chong Han, Carmela Molinaro, C Gregory Sowell, Francis Gosselin
Stereocontrolled Synthesis of Arylomycin-Based Gram-Negative Antibiotic GDC-5338. Organic letters 21 (22) (2019)
Ngiap-Kie Lim, Xin Linghu, Nicholas Wong, Haiming Zhang, C Gregory Sowell, Francis Gosselin
Macrolactamization Approaches to Arylomycin Antibiotics Core. Organic letters 21 (1) (2018)