Haopeng Sun

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 44

Top Topics

Molecular Docking

Histone Deacetylase

Top Venues

Journal of medicinal chemistry

ACS chemical neuroscience

Journal of the American Chemical Society

Angewandte Chemie (International ed. in English)

This page only lists publications with an associated author ORCID identifier.

Publications

Xintong Tang, Yueer Zhou, Yingjie Wang, Yetong Lin, Shuheng Pan, Qianwei Che, Jinpeng Sang, Ziming Gao, Weiting Zhang, Yuanyuan Wang, Guolong Li, Longwei Gao, Zhimei Wang, Xudong Yang, Ao Liu, Suyu Wang, Biao Yu, Peng Xu, Zhe Wang, Zhaolun Zhang, Peng Yang, Weijia Xie, Haopeng Sun, Wei Li
Direct Synthesis of α- and β-2'-Deoxynucleosides with Stereodirecting Phosphine Oxide via Remote Participation. Journal of the American Chemical Society 146 (12) (2024)
Xin Lu, Yueqing Li, Qianwen Guan, Huajing Yang, Yijun Liu, Chenxi Du, Lei Wang, Qinghua Wang, Yuqiong Pei, Liang Wu, Haopeng Sun, Yao Chen
Discovery, Structure-Based Modification, In Vitro , In Vivo , and In Silico Exploration of m -Sulfamoyl Benzoamide Derivatives as Selective Butyrylcholinesterase Inhibitors for Treating Alzheimer's Disease. ACS chemical neuroscience 15 (6) (2024)
Lei Wang, Tianyu Sun, Tengfei Zhen, Wei Li, Huajing Yang, Suyu Wang, Feng Feng, Yao Chen, Haopeng Sun
Butyrylcholinesterase-Activated Near-Infrared Fluorogenic Probe for In Vivo Theranostics of Alzheimer's Disease. Journal of medicinal chemistry 67 (8) (2024)
Xintong Tang, Yueer Zhou, Yingjie Wang, Yetong Lin, Shuheng Pan, Qianwei Che, Jinpeng Sang, Ziming Gao, Weiting Zhang, Yuanyuan Wang, Guolong Li, Longwei Gao, Zhimei Wang, Xudong Yang, Ao Liu, Suyu Wang, Biao Yu, Peng Xu, Zhe Wang, Zhaolun Zhang, Peng Yang, Weijia Xie, Haopeng Sun, Wei Li
Direct Synthesis of α- and β-2'-Deoxynucleosides with Stereodirecting Phosphine Oxide via Remote Participation. Journal of the American Chemical Society 146 (12) (2024)
Qianwen Guan, Shuaishuai Xing, Lei Wang, Jiawei Zhu, Can Guo, Chunlei Xu, Qun Zhao, Yulan Wu, Yao Chen, Haopeng Sun
Triazoles in Medicinal Chemistry: Physicochemical Properties, Bioisosterism, and Application. Journal of medicinal chemistry (2024)
Qianwen Guan, Shuaishuai Xing, Lei Wang, Jiawei Zhu, Can Guo, Chunlei Xu, Qun Zhao, Yulan Wu, Yao Chen, Haopeng Sun
Triazoles in Medicinal Chemistry: Physicochemical Properties, Bioisosterism, and Application. Journal of medicinal chemistry 67 (10) (2024)
Xintong Tang, Yueer Zhou, Yingjie Wang, Yetong Lin, Shuheng Pan, Qianwei Che, Jinpeng Sang, Ziming Gao, Weiting Zhang, Yuanyuan Wang, Guolong Li, Longwei Gao, Zhimei Wang, Xudong Yang, Ao Liu, Suyu Wang, Biao Yu, Peng Xu, Zhe Wang, Zhaolun Zhang, Peng Yang, Weijia Xie, Haopeng Sun, Wei Li
Direct Synthesis of α- and β-2'-Deoxynucleosides with Stereodirecting Phosphine Oxide via Remote Participation. Journal of the American Chemical Society 146 (12) (2024)
Xintong Tang, Yueer Zhou, Yingjie Wang, Yetong Lin, Shuheng Pan, Qianwei Che, Jinpeng Sang, Ziming Gao, Weiting Zhang, Yuanyuan Wang, Guolong Li, Longwei Gao, Zhimei Wang, Xudong Yang, Ao Liu, Suyu Wang, Biao Yu, Peng Xu, Zhe Wang, Zhaolun Zhang, Peng Yang, Weijia Xie, Haopeng Sun, Wei Li
Direct Synthesis of α- and β-2'-Deoxynucleosides with Stereodirecting Phosphine Oxide via Remote Participation. Journal of the American Chemical Society (2024)
Xin Lu, Yueqing Li, Qianwen Guan, Huajing Yang, Yijun Liu, Chenxi Du, Lei Wang, Qinghua Wang, Yuqiong Pei, Liang Wu, Haopeng Sun, Yao Chen
Discovery, Structure-Based Modification, In Vitro , In Vivo , and In Silico Exploration of m -Sulfamoyl Benzoamide Derivatives as Selective Butyrylcholinesterase Inhibitors for Treating Alzheimer's Disease. ACS chemical neuroscience (2024)
Lei Wang, Tianyu Sun, Tengfei Zhen, Wei Li, Huajing Yang, Suyu Wang, Feng Feng, Yao Chen, Haopeng Sun
Butyrylcholinesterase-Activated Near-Infrared Fluorogenic Probe for In Vivo Theranostics of Alzheimer's Disease. Journal of medicinal chemistry (2024)
Xin Lu, Yueqing Li, Qianwen Guan, Huajing Yang, Yijun Liu, Chenxi Du, Lei Wang, Qinghua Wang, Yuqiong Pei, Liang Wu, Haopeng Sun, Yao Chen
Discovery, Structure-Based Modification, In Vitro , In Vivo , and In Silico Exploration of m -Sulfamoyl Benzoamide Derivatives as Selective Butyrylcholinesterase Inhibitors for Treating Alzheimer's Disease. ACS chemical neuroscience 15 (6) (2024)
Xin Lu, Yueqing Li, Qianwen Guan, Huajing Yang, Yijun Liu, Chenxi Du, Lei Wang, Qinghua Wang, Yuqiong Pei, Liang Wu, Haopeng Sun, Yao Chen
Discovery, Structure-Based Modification, In Vitro , In Vivo , and In Silico Exploration of m -Sulfamoyl Benzoamide Derivatives as Selective Butyrylcholinesterase Inhibitors for Treating Alzheimer's Disease. ACS chemical neuroscience 15 (6) (2024)
Xu Tang, Shuaishuai Xing, Mingkang Ma, Ziwei Xu, Qianwen Guan, Yuting Chen, Feng Feng, Wenyuan Liu, Tingkai Chen, Yao Chen, Haopeng Sun
The Development and Design Strategy of Leucine-Rich Repeat Kinase 2 Inhibitors: Promising Therapeutic Agents for Parkinson's Disease. Journal of medicinal chemistry 66 (4) (2023)
Lu Lu, Jingyi Chen, Wenxiang Tao, Zhimei Wang, Dan Liu, Jiahui Zhou, Xiaoxing Wu, Haopeng Sun, Wei Li, Genzoh Tanabe, Osamu Muraoka, Bo Zhao, Liang Wu, Weijia Xie
Design and Synthesis of Sulfonium Derivatives: A Novel Class of α-Glucosidase Inhibitors with Potent In Vivo Antihyperglycemic Activities. Journal of medicinal chemistry 66 (5) (2023)
Lei Wang, Tianyu Sun, Zhenqi Wang, Hui Liu, Weimin Qiu, Xu Tang, Huanchao Guo, Peng Yang, Yao Chen, Haopeng Sun
Design, Synthesis, and Proof of Concept of Balanced Dual Inhibitors of Butyrylcholinesterase (BChE) and Histone Deacetylase 6 (HDAC6) for the Treatment of Alzheimer's Disease. ACS chemical neuroscience (2023)
Siyu He, Xianglin Chu, Yujia Wu, Jiheng Jiang, Pengfei Fang, Yuting Chen, Yang Liu, Zhixia Qiu, Yibei Xiao, Zhiyu Li, Di Pan, Qian Zhang, Huanfang Xie, Shuaishuai Xing, Feng Feng, Wenyuan Liu, Qinglong Guo, Li Zhao, Peng Yang, Haopeng Sun
Development of Biaryl-Containing Aldo-Keto Reductase 1C3 (AKR1C3) Inhibitors for Reversing AKR1C3-Mediated Drug Resistance in Cancer Treatment. Journal of medicinal chemistry (2023)
Xu Tang, Shuaishuai Xing, Mingkang Ma, Ziwei Xu, Qianwen Guan, Yuting Chen, Feng Feng, Wenyuan Liu, Tingkai Chen, Yao Chen, Haopeng Sun
The Development and Design Strategy of Leucine-Rich Repeat Kinase 2 Inhibitors: Promising Therapeutic Agents for Parkinson's Disease. Journal of medicinal chemistry 66 (4) (2023)
Lu Lu, Jingyi Chen, Wenxiang Tao, Zhimei Wang, Dan Liu, Jiahui Zhou, Xiaoxing Wu, Haopeng Sun, Wei Li, Genzoh Tanabe, Osamu Muraoka, Bo Zhao, Liang Wu, Weijia Xie
Design and Synthesis of Sulfonium Derivatives: A Novel Class of α-Glucosidase Inhibitors with Potent In Vivo Antihyperglycemic Activities. Journal of medicinal chemistry 66 (5) (2023)
Xu Tang, Shuaishuai Xing, Mingkang Ma, Ziwei Xu, Qianwen Guan, Yuting Chen, Feng Feng, Wenyuan Liu, Tingkai Chen, Yao Chen, Haopeng Sun
The Development and Design Strategy of Leucine-Rich Repeat Kinase 2 Inhibitors: Promising Therapeutic Agents for Parkinson's Disease. Journal of medicinal chemistry 66 (4) (2023)
Lu Lu, Jingyi Chen, Wenxiang Tao, Zhimei Wang, Dan Liu, Jiahui Zhou, Xiaoxing Wu, Haopeng Sun, Wei Li, Genzoh Tanabe, Osamu Muraoka, Bo Zhao, Liang Wu, Weijia Xie
Design and Synthesis of Sulfonium Derivatives: A Novel Class of α-Glucosidase Inhibitors with Potent In Vivo Antihyperglycemic Activities. Journal of medicinal chemistry (2023)
Xu Tang, Shuaishuai Xing, Mingkang Ma, Ziwei Xu, Qianwen Guan, Yuting Chen, Feng Feng, Wenyuan Liu, Tingkai Chen, Yao Chen, Haopeng Sun
The Development and Design Strategy of Leucine-Rich Repeat Kinase 2 Inhibitors: Promising Therapeutic Agents for Parkinson's Disease. Journal of medicinal chemistry (2023)
Weimin Qiu, Hui Liu, Yijun Liu, Xin Lu, Lei Wang, Yanyu Hu, Feng Feng, Qi Li, Haopeng Sun
Regulation of beta-amyloid for the treatment of Alzheimer's disease: Research progress of therapeutic strategies and bioactive compounds. Medicinal research reviews (2023)
Xu Tang, Shuaishuai Xing, Mingkang Ma, Ziwei Xu, Qianwen Guan, Yuting Chen, Feng Feng, Wenyuan Liu, Tingkai Chen, Yao Chen, Haopeng Sun
The Development and Design Strategy of Leucine-Rich Repeat Kinase 2 Inhibitors: Promising Therapeutic Agents for Parkinson's Disease. Journal of medicinal chemistry 66 (4) (2023)
Haojie Dong, Xiuquan Ye, Yasheng Zhu, Hao Shen, Hongtao Shen, Weijiao Chen, Minghui Ji, Mingming Zheng, Keren Wang, Zeyu Cai, Haopeng Sun, Yibei Xiao, Peng Yang
Discovery of Potent and Wild-Type-Sparing Fourth-Generation EGFR Inhibitors for Treatment of Osimertinib-Resistance NSCLC. Journal of medicinal chemistry (2023)
Lu Lu, Jingyi Chen, Wenxiang Tao, Zhimei Wang, Dan Liu, Jiahui Zhou, Xiaoxing Wu, Haopeng Sun, Wei Li, Genzoh Tanabe, Osamu Muraoka, Bo Zhao, Liang Wu, Weijia Xie
Design and Synthesis of Sulfonium Derivatives: A Novel Class of α-Glucosidase Inhibitors with Potent In Vivo Antihyperglycemic Activities. Journal of medicinal chemistry 66 (5) (2023)
Xianglai Liu, Yetong Lin, Wenyi Peng, Zhaolun Zhang, Longwei Gao, Yueer Zhou, Zhe Song, Yingjie Wang, Peng Xu, Biao Yu, Haopeng Sun, Weijia Xie, Wei Li
Direct Synthesis of 2,6-Dideoxy-β-glycosides and β-Rhamnosides with a Stereodirecting 2-(Diphenylphosphinoyl)acetyl Group. Angewandte Chemie (International ed. in English) 61 (33) (2022)
Tingkai Chen, Tianyu Sun, Yaoyao Bian, Yuqiong Pei, Feng Feng, Heng Chi, Yuan Li, Xu Tang, Shenghu Sang, Chenxi Du, Ying Chen, Yao Chen, Haopeng Sun
The Design and Optimization of Monomeric Multitarget Peptides for the Treatment of Multifactorial Diseases. Journal of medicinal chemistry 65 (5) (2022)
Chenxi Du, Lei Wang, Qianwen Guan, Hongyu Yang, Tingkai Chen, Yijun Liu, Qihang Li, Weiping Lyu, Xin Lu, Ying Chen, Yang Liu, Hui Liu, Feng Feng, Wenyuan Liu, Zongliang Liu, Wei Li, Yao Chen, Haopeng Sun
N -Benzyl Benzamide Derivatives as Selective Sub-Nanomolar Butyrylcholinesterase Inhibitors for Possible Treatment in Advanced Alzheimer's Disease. Journal of medicinal chemistry 65 (16) (2022)
Di Pan, Wanwan Yang, Yao Zeng, Hongkun Qin, Yuting Xu, Yanping Gui, Xiangshan Fan, Geng Tian, Yujia Wu, Haopeng Sun, Yuting Ye, Shihe Yang, Jieying Zhou, Qinglong Guo, Li Zhao
AKR1C3 regulated by NRF2/MAFG complex promotes proliferation via stabilizing PARP1 in hepatocellular carcinoma. Oncogene 41 (31) (2022)
Xianglai Liu, Yingying Song, Ao Liu, Yueer Zhou, Qian Zhu, Yetong Lin, Huiyong Sun, Kaidi Zhu, Wei Liu, Yingxia Li, Weijia Xie, Haopeng Sun, Biao Yu, Peng Xu, Wei Li
More than a Leaving Group: N-Phenyltrifluoroacetimidate as a Remote Directing Group for Highly α-Selective 1,2-cis Glycosylation. Angewandte Chemie (International ed. in English) 61 (21) (2022)
Lili Yang, Zhengjun Li, Yao Chen, Feiyan Chen, Haopeng Sun, Min Zhao, Yanqi Chen, Yali Wang, Wenlin Li, Li Zeng, Yao-Yao Bian
Elucidating the Novel Mechanism of Ligustrazine in Preventing Postoperative Peritoneal Adhesion Formation. Oxidative medicine and cellular longevity 2022 (2022)
Siyu He, Yang Liu, Xianglin Chu, Qi Li, Weiping Lyu, Yijun Liu, Shuaishuai Xing, Feng Feng, Wenyuan Liu, Qinglong Guo, Li Zhao, Haopeng Sun
Discovery of Novel Aldo-Keto Reductase 1C3 Inhibitors as Chemotherapeutic Potentiators for Cancer Drug Resistance. ACS medicinal chemistry letters 13 (8) (2022)
Siyu He, Yang Liu, Qihang Li, Weiping Lyu, Feng Feng, Qinglong Guo, Li Zhao, Haopeng Sun
In silico approaches using pharmacophore model combined with molecular docking for discovery of novel ULK1 inhibitors. Future medicinal chemistry 13 (4) (2021)
Qi Li, Ying Chen, Shuaishuai Xing, Qinghong Liao, Baichen Xiong, Yuanyuan Wang, Weixuan Lu, Siyu He, Feng Feng, Wenyuan Liu, Yao Chen, Haopeng Sun
Highly Potent and Selective Butyrylcholinesterase Inhibitors for Cognitive Improvement and Neuroprotection. Journal of medicinal chemistry 64 (10) (2021)
Qi Li, Jun Mo, Baichen Xiong, Qinghong Liao, Ying Chen, Yuanyuan Wang, Shuaishuai Xing, Siyu He, Weiping Lyu, Ning Zhang, Haopeng Sun
Discovery of Resorcinol-Based Polycyclic Structures as Tyrosinase Inhibitors for Treatment of Parkinson's Disease. ACS chemical neuroscience (2021)
Chenxi Du, Hongyu Yang, Feng Feng, Wenyuan Liu, Yao Chen, Haopeng Sun
Achieving effective and selective CK1 inhibitors through structure modification. Future medicinal chemistry 13 (5) (2021)
Baichen Xiong, Yuanyuan Wang, Ying Chen, Shuaishuai Xing, Qinghong Liao, Yao Chen, Qi Li, Wei Li, Haopeng Sun
Strategies for Structural Modification of Small Molecules to Improve Blood-Brain Barrier Penetration: A Recent Perspective. Journal of medicinal chemistry 64 (18) (2021)
Weiping Lyu, Qihang Li, Qi Li, Ying Chen, Yingming Wang, Tongzhong Tang, Feng Feng, Heng Chi, Yuan Li, Wenyuan Liu, Haopeng Sun
Design, Bio-evaluation and Molecular Dynamics Simulation of Novel GSK-3β Inhibitors. Molecular informatics 40 (12) (2021)
Yang Liu, Siyu He, Ying Chen, Yijun Liu, Feng Feng, Wenyuan Liu, Qinglong Guo, Li Zhao, Haopeng Sun
Overview of AKR1C3: Inhibitor Achievements and Disease Insights. Journal of medicinal chemistry 63 (20) (2020)
Qi Li, Shuaishuai Xing, Ying Chen, Qinghong Liao, Baichen Xiong, Siyu He, Weixuan Lu, Yang Liu, Hongyu Yang, Qihang Li, Feng Feng, Wenyuan Liu, Yao Chen, Haopeng Sun
Discovery and Biological Evaluation of a Novel Highly Potent Selective Butyrylcholinsterase Inhibitor. Journal of medicinal chemistry 63 (17) (2020)
Ying Chen, Qi Li, Qihang Li, Shuaishuai Xing, Yang Liu, Yijun Liu, Yao Chen, Wenyuan Liu, Feng Feng, Haopeng Sun
p62/SQSTM1, a Central but Unexploited Target: Advances in Its Physiological/Pathogenic Functions and Small Molecular Modulators. Journal of medicinal chemistry 63 (18) (2020)
Junting Zhou, Xueyang Jiang, Siyu He, Hongli Jiang, Feng Feng, Wenyuan Liu, Wei Qu, Haopeng Sun
Rational Design of Multitarget-Directed Ligands: Strategies and Emerging Paradigms. Journal of medicinal chemistry 62 (20) (2019)
Hui Qin, Qi Li, Jian Xu, Jie Zhang, Wei Qu, Wenyuan Liu, Feng Feng, Haopeng Sun
A Mild and Direct C(sp3)-S Cross-Coupling of Oxindoles with Thiols: Synthesis of Unsymmetrical 3-Thiooxindoles. The Journal of organic chemistry 84 (21) (2019)
Siyu He, Qi Li, Xueyang Jiang, Xin Lu, Feng Feng, Wei Qu, Yao Chen, Haopeng Sun
Design of Small Molecule Autophagy Modulators: A Promising Druggable Strategy. Journal of medicinal chemistry 61 (11) (2017)