Pengfei Fang

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 40

Top Venues

Communications biology

Proceedings of the National Academy of Sciences of the United States of America

Cell research

Organic & biomolecular chemistry

Shanghai Institute of Organic Chemistry

University of Science and Technology of China (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Shanghai Institute of Organic Chemistry

China

Professor

Education History

University of Science and Technology of China

China

PHD

University of Science and Technology of China

China

BSC

Publications

Jintong Zhou, Mingyu Xia, Zhenghui Huang, Hang Qiao, Guang Yang, Yunan Qian, Peifeng Li, Zhaolun Zhang, Xinai Gao, Lubin Jiang, Jing Wang, Wei Li, Pengfei Fang
Structure-guided conversion from an anaplastic lymphoma kinase inhibitor into Plasmodium lysyl-tRNA synthetase selective inhibitors. Communications biology 7 (1) (2024)
Danna Dong, Mingyu Xia, Sili Wang, Pengfei Fang, Wen Liu
Structural Basis of Substrate Recognition by the Postmitosane Modification Enzyme MitM in Mitomycin Biosynthesis. Biochemistry 63 (17) (2024)
Jintong Zhou, Mingyu Xia, Zhenghui Huang, Hang Qiao, Guang Yang, Yunan Qian, Peifeng Li, Zhaolun Zhang, Xinai Gao, Lubin Jiang, Jing Wang, Wei Li, Pengfei Fang
Structure-guided conversion from an anaplastic lymphoma kinase inhibitor into Plasmodium lysyl-tRNA synthetase selective inhibitors. Communications biology 7 (1) (2024)
Yirong Zhu, Xiaotong Wang, Siqian Lu, Jibin Zheng, Youling Liang, Liangliang Zhang, Pengfei Fang, Peng Xu, Biao Yu, You Yang
Microwave-assisted synthesis of highly sulfated mannuronate glycans as potential inhibitors against SARS-CoV-2. Organic & biomolecular chemistry 22 (19) (2024)
Hang Qiao, Zilu Wang, Hao Yang, Mingyu Xia, Guang Yang, Fang Bai, Jing Wang, Pengfei Fang
Specific glycine-dependent enzyme motion determines the potency of conformation selective inhibitors of threonyl-tRNA synthetase. Communications biology 7 (1) (2024)
Yirong Zhu, Xiaotong Wang, Siqian Lu, Jibin Zheng, Youling Liang, Liangliang Zhang, Pengfei Fang, Peng Xu, Biao Yu, You Yang
Microwave-assisted synthesis of highly sulfated mannuronate glycans as potential inhibitors against SARS-CoV-2. Organic & biomolecular chemistry (2024)
Jintong Zhou, Mingyu Xia, Zhenghui Huang, Hang Qiao, Guang Yang, Yunan Qian, Peifeng Li, Zhaolun Zhang, Xinai Gao, Lubin Jiang, Jing Wang, Wei Li, Pengfei Fang
Structure-guided conversion from an anaplastic lymphoma kinase inhibitor into Plasmodium lysyl-tRNA synthetase selective inhibitors. Communications biology 7 (1) (2024)
Yirong Zhu, Xiaotong Wang, Siqian Lu, Jibin Zheng, Youling Liang, Liangliang Zhang, Pengfei Fang, Peng Xu, Biao Yu, You Yang
Microwave-assisted synthesis of highly sulfated mannuronate glycans as potential inhibitors against SARS-CoV-2. Organic & biomolecular chemistry 22 (19) (2024)
Danna Dong, Mingyu Xia, Sili Wang, Pengfei Fang, Wen Liu
Structural Basis of Substrate Recognition by the Postmitosane Modification Enzyme MitM in Mitomycin Biosynthesis. Biochemistry (2024)
Hang Qiao, Zilu Wang, Hao Yang, Mingyu Xia, Guang Yang, Fang Bai, Jing Wang, Pengfei Fang
Specific glycine-dependent enzyme motion determines the potency of conformation selective inhibitors of threonyl-tRNA synthetase. Communications biology 7 (1) (2024)
Jintong Zhou, Mingyu Xia, Zhenghui Huang, Hang Qiao, Guang Yang, Yunan Qian, Peifeng Li, Zhaolun Zhang, Xinai Gao, Lubin Jiang, Jing Wang, Wei Li, Pengfei Fang
Structure-guided conversion from an anaplastic lymphoma kinase inhibitor into Plasmodium lysyl-tRNA synthetase selective inhibitors. Communications biology 7 (1) (2024)
Hang Qiao, Zilu Wang, Hao Yang, Mingyu Xia, Guang Yang, Fang Bai, Jing Wang, Pengfei Fang
Specific glycine-dependent enzyme motion determines the potency of conformation selective inhibitors of threonyl-tRNA synthetase. Communications biology 7 (1) (2024)
Yuhan Dai, Yiyuan Cheng, Weizhong Ding, Hang Qiao, Derundong Zhang, Guannan Zhong, Mingyu Xia, Jiang Tao, Peng Sun, Pengfei Fang, Wen Liu
Structural Basis of Low-Molecular-Weight Thiol Glycosylation in Lincomycin A Biosynthesis. ACS chemical biology (2023)
Zaizhou Liu, Kaige Chen, Jun Dai, Peng Xu, Wei Sun, Wanlin Liu, Zhixin Zhao, Steven P Bennett, Peifeng Li, Tiancheng Ma, Yuqi Lin, Akinori Kawakami, Jing Yu, Fei Wang, Chunxi Wang, Miao Li, Peter Chase, Peter Hodder, Timothy P Spicer, Louis Scampavia, Chunyang Cao, Lifeng Pan, Jiajia Dong, Yong Chen, Biao Yu, Min Guo, Pengfei Fang, David E Fisher, Jing Wang
A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy. Cell research 33 (1) (2023)
Hang Qiao, Mingyu Xia, Yiyuan Cheng, Jintong Zhou, Li Zheng, Wei Li, Jing Wang, Pengfei Fang
Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion. Communications biology 6 (1) (2023)
Yuqi Lin, Qiqi Shi, Guang Yang, Fuchun Shi, Yang Zhou, Tongtong Wang, Biao Yu, Peifeng Li, Zaizhou Liu, Hanyin Sun, Zhixin Zhao, Ke Ding, Zhen Wang, Haizhong Feng, Biao Yu, Pengfei Fang, Jing Wang
A small-molecule drug inhibits autophagy gene expression through the central regulator TFEB. Proceedings of the National Academy of Sciences of the United States of America 120 (7) (2023)
Yiyuan Cheng, Xuan Yi, Yan Zhang, Qing-Li He, Dandan Chen, Weiguo Cao, Pengfei Fang, Wen Liu
Oxidase Heterotetramer Completes 1-Azabicyclo[3.1.0]hexane Formation with the Association of a Nonribosomal Peptide Synthetase. Journal of the American Chemical Society (2023)
Hang Qiao, Mingyu Xia, Yiyuan Cheng, Jintong Zhou, Li Zheng, Wei Li, Jing Wang, Pengfei Fang
Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion. Communications biology 6 (1) (2023)
Zaizhou Liu, Kaige Chen, Jun Dai, Peng Xu, Wei Sun, Wanlin Liu, Zhixin Zhao, Steven P Bennett, Peifeng Li, Tiancheng Ma, Yuqi Lin, Akinori Kawakami, Jing Yu, Fei Wang, Chunxi Wang, Miao Li, Peter Chase, Peter Hodder, Timothy P Spicer, Louis Scampavia, Chunyang Cao, Lifeng Pan, Jiajia Dong, Yong Chen, Biao Yu, Min Guo, Pengfei Fang, David E Fisher, Jing Wang
A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy. Cell research 33 (1) (2023)
Hang Qiao, Mingyu Xia, Yiyuan Cheng, Jintong Zhou, Li Zheng, Wei Li, Jing Wang, Pengfei Fang
Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion. Communications biology 6 (1) (2023)
Hang Qiao, Mingyu Xia, Yiyuan Cheng, Jintong Zhou, Li Zheng, Wei Li, Jing Wang, Pengfei Fang
Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion. Communications biology 6 (1) (2023)
Hang Qiao, Mingyu Xia, Yiyuan Cheng, Jintong Zhou, Li Zheng, Wei Li, Jing Wang, Pengfei Fang
Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion. Communications biology 6 (1) (2023)
Zaizhou Liu, Kaige Chen, Jun Dai, Peng Xu, Wei Sun, Wanlin Liu, Zhixin Zhao, Steven P Bennett, Peifeng Li, Tiancheng Ma, Yuqi Lin, Akinori Kawakami, Jing Yu, Fei Wang, Chunxi Wang, Miao Li, Peter Chase, Peter Hodder, Timothy P Spicer, Louis Scampavia, Chunyang Cao, Lifeng Pan, Jiajia Dong, Yong Chen, Biao Yu, Min Guo, Pengfei Fang, David E Fisher, Jing Wang
A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy. Cell research 33 (1) (2023)
Yuqi Lin, Qiqi Shi, Guang Yang, Fuchun Shi, Yang Zhou, Tongtong Wang, Biao Yu, Peifeng Li, Zaizhou Liu, Hanyin Sun, Zhixin Zhao, Ke Ding, Zhen Wang, Haizhong Feng, Biao Yu, Pengfei Fang, Jing Wang
A small-molecule drug inhibits autophagy gene expression through the central regulator TFEB. Proceedings of the National Academy of Sciences of the United States of America 120 (7) (2023)
Yuqi Lin, Qiqi Shi, Guang Yang, Fuchun Shi, Yang Zhou, Tongtong Wang, Biao Yu, Peifeng Li, Zaizhou Liu, Hanyin Sun, Zhixin Zhao, Ke Ding, Zhen Wang, Haizhong Feng, Biao Yu, Pengfei Fang, Jing Wang
A small-molecule drug inhibits autophagy gene expression through the central regulator TFEB. Proceedings of the National Academy of Sciences of the United States of America 120 (7) (2023)
Siyu He, Xianglin Chu, Yujia Wu, Jiheng Jiang, Pengfei Fang, Yuting Chen, Yang Liu, Zhixia Qiu, Yibei Xiao, Zhiyu Li, Di Pan, Qian Zhang, Huanfang Xie, Shuaishuai Xing, Feng Feng, Wenyuan Liu, Qinglong Guo, Li Zhao, Peng Yang, Haopeng Sun
Development of Biaryl-Containing Aldo-Keto Reductase 1C3 (AKR1C3) Inhibitors for Reversing AKR1C3-Mediated Drug Resistance in Cancer Treatment. Journal of medicinal chemistry (2023)
Zaizhou Liu, Kaige Chen, Jun Dai, Peng Xu, Wei Sun, Wanlin Liu, Zhixin Zhao, Steven P Bennett, Peifeng Li, Tiancheng Ma, Yuqi Lin, Akinori Kawakami, Jing Yu, Fei Wang, Chunxi Wang, Miao Li, Peter Chase, Peter Hodder, Timothy P Spicer, Louis Scampavia, Chunyang Cao, Lifeng Pan, Jiajia Dong, Yong Chen, Biao Yu, Min Guo, Pengfei Fang, David E Fisher, Jing Wang
A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy. Cell research (2023)
Yuqi Lin, Qiqi Shi, Guang Yang, Fuchun Shi, Yang Zhou, Tongtong Wang, Biao Yu, Peifeng Li, Zaizhou Liu, Hanyin Sun, Zhixin Zhao, Ke Ding, Zhen Wang, Haizhong Feng, Biao Yu, Pengfei Fang, Jing Wang
A small-molecule drug inhibits autophagy gene expression through the central regulator TFEB. Proceedings of the National Academy of Sciences of the United States of America 120 (7) (2023)
Yuqi Lin, Biao Yu, Pengfei Fang, Jing Wang
Inhibiting autophagy before it starts. Autophagy (2023)
Zaizhou Liu, Kaige Chen, Jun Dai, Peng Xu, Wei Sun, Wanlin Liu, Zhixin Zhao, Steven P Bennett, Peifeng Li, Tiancheng Ma, Yuqi Lin, Akinori Kawakami, Jing Yu, Fei Wang, Chunxi Wang, Miao Li, Peter Chase, Peter Hodder, Timothy P Spicer, Louis Scampavia, Chunyang Cao, Lifeng Pan, Jiajia Dong, Yong Chen, Biao Yu, Min Guo, Pengfei Fang, David E Fisher, Jing Wang
A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy. Cell research 33 (1) (2023)
Zaizhou Liu, Kaige Chen, Jun Dai, Peng Xu, Wei Sun, Wanlin Liu, Zhixin Zhao, Steven P Bennett, Peifeng Li, Tiancheng Ma, Yuqi Lin, Akinori Kawakami, Jing Yu, Fei Wang, Chunxi Wang, Miao Li, Peter Chase, Peter Hodder, Timothy P Spicer, Louis Scampavia, Chunyang Cao, Lifeng Pan, Jiajia Dong, Yong Chen, Biao Yu, Min Guo, Pengfei Fang, David E Fisher, Jing Wang
A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy. Cell research 33 (1) (2023)
Yuqi Lin, Qiqi Shi, Guang Yang, Fuchun Shi, Yang Zhou, Tongtong Wang, Biao Yu, Peifeng Li, Zaizhou Liu, Hanyin Sun, Zhixin Zhao, Ke Ding, Zhen Wang, Haizhong Feng, Biao Yu, Pengfei Fang, Jing Wang
A small-molecule drug inhibits autophagy gene expression through the central regulator TFEB. Proceedings of the National Academy of Sciences of the United States of America 120 (7) (2023)
Yingke Tang, Ryan T Behrens, Corine St Gelais, Siqi Wu, Saravanan Vivekanandan, Ehud Razin, Pengfei Fang, Li Wu, Nathan M Sherer, Karin Musier-Forsyth
Human lysyl-tRNA synthetase phosphorylation promotes HIV-1 proviral DNA transcription. Nucleic acids research (2023)
Yuqi Lin, Qiqi Shi, Guang Yang, Fuchun Shi, Yang Zhou, Tongtong Wang, Biao Yu, Peifeng Li, Zaizhou Liu, Hanyin Sun, Zhixin Zhao, Ke Ding, Zhen Wang, Haizhong Feng, Biao Yu, Pengfei Fang, Jing Wang
A small-molecule drug inhibits autophagy gene expression through the central regulator TFEB. Proceedings of the National Academy of Sciences of the United States of America 120 (7) (2023)
Yuqi Lin, Qiqi Shi, Guang Yang, Fuchun Shi, Yang Zhou, Tongtong Wang, Biao Yu, Peifeng Li, Zaizhou Liu, Hanyin Sun, Zhixin Zhao, Ke Ding, Zhen Wang, Haizhong Feng, Biao Yu, Pengfei Fang, Jing Wang
A small-molecule drug inhibits autophagy gene expression through the central regulator TFEB. Proceedings of the National Academy of Sciences of the United States of America 120 (7) (2023)
Siqi Wu, Li Zheng, Zhoufei Hei, Jing-Bo Zhou, Guang Li, Peifeng Li, Jiayuan Wang, Hamid Ali, Xiao-Long Zhou, Jing Wang, Pengfei Fang
Human lysyl-tRNA synthetase evolves a dynamic structure that can be stabilized by forming complex. Cellular and molecular life sciences : CMLS 79 (2) (2022)
Tingting Yu, Yi Zhang, Wen-Qiang Zheng, Siqi Wu, Guoqiang Li, Yong Zhang, Niu Li, Ruen Yao, Pengfei Fang, Jian Wang, Xiao-Long Zhou
Selective degradation of tRNASer(AGY) is the primary driver for mitochondrial seryl-tRNA synthetase-related disease. Nucleic acids research 50 (20) (2022)
Jintong Zhou, Li Zheng, Zhoufei Hei, Wei Li, Jing Wang, Biao Yu, Pengfei Fang
Atomic Resolution Analyses of Isocoumarin Derivatives for Inhibition of Lysyl-tRNA Synthetase. ACS chemical biology 15 (4) (2020)
Jing Yu, Zaizhou Liu, Yuanyuan Liang, Feng Luo, Jie Zhang, Cuiping Tian, Alex Motzik, Mengmeng Zheng, Jingwu Kang, Guisheng Zhong, Cong Liu, Pengfei Fang, Min Guo, Ehud Razin, Jing Wang
Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in FcεRI-activated mast cells. Nature communications 10 (1) (2019)
Zhoufei Hei, Siqi Wu, Zaizhou Liu, Jing Wang, Pengfei Fang
Retractile lysyl-tRNA synthetase-AIMP2 assembly in the human multi-aminoacyl-tRNA synthetase complex. The Journal of biological chemistry 294 (13) (2019)

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Publication Activity (10 Years)

Top Topics

Top Venues

Pengfei Fang