Harun M Patel (H Patel, Harun Patel)

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 51

Top Topics

Molecular Docking

Epidermal Growth Factor Receptor

Top Venues

Journal of biomolecular structure & dynamics

Molecules (Basel, Switzerland)

ACS medicinal chemistry letters

This page only lists publications with an associated author ORCID identifier.

Publications

Iqrar Ahmad Ansari, Harun M Patel
Repurposing Non-Nucleosidic Reverse Transcriptase Inhibitors (NNRTIs) to Overcome EGFR T790M-Mediated Acquired Resistance in Non-Small Cell Lung Cancer. Journal of cellular biochemistry (2024)
Rukaiyya T Girase, Iqrar Ahmad, Jong Min Oh, Bijo Mathew, Siva K Vagolu, Tone Tønjum, Dharmarajan Sriram, Jyothi Kumari, Nisheeth C Desai, Yogesh Agrawal, Hoon Kim, Harun M Patel
Design and Synthesis of the Linezolid Bioisosteres to Resolve the Serotonergic Toxicity Associated with Linezolid. ACS medicinal chemistry letters 15 (6) (2024)
Ayşen Işık, Ulviye Acar Çevi K, Arzu Karayel, Iqrar Ahmad, Harun M Patel, İsmail Çelik, Ülküye Dudu Gül, Gizem Bayazıt, Hayrani Eren Bostancı, Ahmet Koçak, Yusuf Özkay, Zafer Asım Kaplancıklı
Synthesis, DFT Calculations, In Silico Studies, and Antimicrobial Evaluation of Benzimidazole-Thiadiazole Derivatives. ACS omega 9 (16) (2024)
Rukaiyya T Girase, Iqrar Ahmad, Jong Min Oh, Bijo Mathew, Siva K Vagolu, Tone Tønjum, Dharmarajan Sriram, Jyothi Kumari, Nisheeth C Desai, Yogesh Agrawal, Hoon Kim, Harun M Patel
Design and Synthesis of the Linezolid Bioisosteres to Resolve the Serotonergic Toxicity Associated with Linezolid. ACS medicinal chemistry letters 15 (6) (2024)
Ayşen Işık, Ulviye Acar Çevi K, Arzu Karayel, Iqrar Ahmad, Harun M Patel, İsmail Çelik, Ülküye Dudu Gül, Gizem Bayazıt, Hayrani Eren Bostancı, Ahmet Koçak, Yusuf Özkay, Zafer Asım Kaplancıklı
Synthesis, DFT Calculations, In Silico Studies, and Antimicrobial Evaluation of Benzimidazole-Thiadiazole Derivatives. ACS omega 9 (16) (2024)
Rukaiyya T Girase, Iqrar Ahmad, Jong Min Oh, Hoon Kim, Bijo Mathew, Siva K Vagolu, Tone Tønjum, Nisheeth C Desai, Dharmarajan Sriram, Jyothi Kumari, Harun M Patel
Repurposing Azoles to Resolve Serotogenic Toxicity Associated with Linezolid to Combat Multidrug-Resistant Tuberculosis. ACS medicinal chemistry letters 14 (12) (2023)
Vilas R Jagatap, Iqrar Ahmad, Dharmarajan Sriram, Jyothi Kumari, Darko Kwabena Adu, Blessing Wisdom Ike, Meenu Ghai, Siddique Akber Ansari, Irfan Aamer Ansari, Priscille Ornella Mefotso Wetchoua, Rajshekhar Karpoormath, Harun M Patel
Isoflavonoid and Furanochromone Natural Products as Potential DNA Gyrase Inhibitors: Computational, Spectral, and Antimycobacterial Studies. ACS omega 8 (18) (2023)
Rukaiyya T Girase, Iqrar Ahmad, Jong Min Oh, Hoon Kim, Bijo Mathew, Siva K Vagolu, Tone Tønjum, Nisheeth C Desai, Dharmarajan Sriram, Jyothi Kumari, Harun M Patel
Repurposing Azoles to Resolve Serotogenic Toxicity Associated with Linezolid to Combat Multidrug-Resistant Tuberculosis. ACS medicinal chemistry letters 14 (12) (2023)
Mustapha Abdullahi, Adamu Uzairu, Gideon Adamu Shallangwa, Paul Andrew Mamza, Muhammad Tukur Ibrahim, Iqrar Ahmad Ansari, Harun M Patel
Structure-based drug design, molecular dynamics simulation, ADMET, and quantum chemical studies of some thiazolinones targeting influenza neuraminidase. Journal of biomolecular structure & dynamics (2023)
Sunil Kumar, Jong Min Oh, Mohamed A Abdelgawad, Mohammed A S Abourehab, Anand Kumar Tengli, Ashutosh Kumar Singh, Iqrar Ahmad, Harun M Patel, Bijo Mathew, Hoon Kim
Development of Isopropyl-Tailed Chalcones as a New Class of Selective MAO-B Inhibitors for the Treatment of Parkinson's Disorder. ACS omega 8 (7) (2023)
Tilal Elsaman, Iqrar Ahmad Ansari, Eyman Mohamed Eltayib, Malik Suliman Mohamed, Osman Yusuf, Mohamed Saeed, Harun M Patel, Magdi Awadalla Mohamed
Flavonostilbenes natural hybrids from Rhamnoneuron balansae as potential antitumors targeting ALDH1A1: molecular docking, ADMET, MM-GBSA calculations and molecular dynamics studies. Journal of biomolecular structure & dynamics (2023)
Ajayrajsinh R Zala, Dhanji P Rajani, Iqrar Ahmad Ansari, Harun M Patel, Premlata Kumari
Synthesis, characterization, molecular dynamic simulation, and biological assessment of cinnamates linked to imidazole/benzimidazole as a CYP51 inhibitor. Journal of biomolecular structure & dynamics (2023)
Vilas R Jagatap, Iqrar Ahmad, Dharmarajan Sriram, Jyothi Kumari, Darko Kwabena Adu, Blessing Wisdom Ike, Meenu Ghai, Siddique Akber Ansari, Irfan Aamer Ansari, Priscille Ornella Mefotso Wetchoua, Rajshekhar Karpoormath, Harun M Patel
Isoflavonoid and Furanochromone Natural Products as Potential DNA Gyrase Inhibitors: Computational, Spectral, and Antimycobacterial Studies. ACS omega 8 (18) (2023)
Sunil Kumar, Jong Min Oh, Mohamed A Abdelgawad, Mohammed A S Abourehab, Anand Kumar Tengli, Ashutosh Kumar Singh, Iqrar Ahmad, Harun M Patel, Bijo Mathew, Hoon Kim
Development of Isopropyl-Tailed Chalcones as a New Class of Selective MAO-B Inhibitors for the Treatment of Parkinson's Disorder. ACS omega 8 (7) (2023)
null Anjali, Payal Kamboj, Ozair Alam, Harun M Patel, Iqrar Ahmad, Syed Sufian Ahmad, Mohammad Amir
Design, synthesis, biological evaluation, and in silico studies of quinoxaline derivatives as potent p38α MAPK inhibitors. Archiv der Pharmazie (2023)
Vilas R Jagatap, Iqrar Ahmad, Dharmarajan Sriram, Jyothi Kumari, Darko Kwabena Adu, Blessing Wisdom Ike, Meenu Ghai, Siddique Akber Ansari, Irfan Aamer Ansari, Priscille Ornella Mefotso Wetchoua, Rajshekhar Karpoormath, Harun M Patel
Isoflavonoid and Furanochromone Natural Products as Potential DNA Gyrase Inhibitors: Computational, Spectral, and Antimycobacterial Studies. ACS omega 8 (18) (2023)
Jaikanth Chandrasekaran, Yogeetha Sivakumaresan, Keerthika Shankar, Melphiya Dickson, Shruthi Laya Saravana Kumar, Lalitha Ramanathan, Iqrar Ahmad Ansari, Harun M Patel
Broadening the scope of WEE1 inhibitors: identifying novel drug candidates via computational approaches and drug repurposing. Journal of biomolecular structure & dynamics (2023)
Sunil R Tivari, Siddhant V Kokate, José L Belmonte-Vázquez, Tushar Janardan Pawar, Harun M Patel, Iqrar Ahmad, Manoj S Gayke, Rajesh S Bhosale, Vicky D Jain, Ghazala Muteeb, Enrique Delgado-Alvarado, Yashwantsinh Jadeja
Synthesis and Evaluation of Biological Activities for a Novel 1,2,3,4-Tetrahydroisoquinoline Conjugate with Dipeptide Derivatives: Insights from Molecular Docking and Molecular Dynamics Simulations. ACS omega 8 (51) (2023)
Emira Noumi, Iqrar Ahmad Ansari, Mohd Adnan, Harun M Patel, Abderrahmen Merghni, Najla Haddaji, Nouha Bouali, Khulood Fahad Alabbosh, Adel Kadri, Lucia Caputo, Flavio Polito, Emira Noumi, Vincenzo De Feo
Illicium verum L. (Star Anise) Essential Oil: GC/MS Profile, Molecular Docking Study, In Silico ADME Profiling, Quorum Sensing, and Biofilm-Inhibiting Effect on Foodborne Bacteria. Molecules (Basel, Switzerland) 28 (23) (2023)
Emira Noumi, Iqrar Ahmad Ansari, Mohd Adnan, Abderrahmen Merghni, Harun M Patel, Najla Haddaji, Nouha Bouali, Khulood Fahad Alabbosh, Siwar Ghannay, Kaïss Aouadi, Adel Kadri, Flavio Polito, Emira Noumi, Vincenzo De Feo
GC/MS Profiling, Antibacterial, Anti-Quorum Sensing, and Antibiofilm Properties of Anethum graveolens L. Essential Oil: Molecular Docking Study and In-Silico ADME Profiling. Plants (Basel, Switzerland) 12 (10) (2023)
Parth P Patel, Navin B Patel, Manesh S Tople, Vatsal M Patel, Iqrar Ahmad Ansari, Harun M Patel
Microwave produced 8-methyl-1,2,4,8-tetraazaspiro[4.5]dec-2-en-3-amine derivatives: their in vitro and in silico analysis. Molecular diversity (2023)
Sunil R Tivari, Siddhant V Kokate, José L Belmonte-Vázquez, Tushar Janardan Pawar, Harun M Patel, Iqrar Ahmad, Manoj S Gayke, Rajesh S Bhosale, Vicky D Jain, Ghazala Muteeb, Enrique Delgado-Alvarado, Yashwantsinh Jadeja
Synthesis and Evaluation of Biological Activities for a Novel 1,2,3,4-Tetrahydroisoquinoline Conjugate with Dipeptide Derivatives: Insights from Molecular Docking and Molecular Dynamics Simulations. ACS omega 8 (51) (2023)
Emira Noumi, Iqrar Ahmad Ansari, Nouha Bouali, Harun M Patel, Siwar Ghannay, Ayshah Aysh ALrashidi, Mohammad A Abdulhakeem, Mitesh Patel, Ozgur Ceylan, Riadh Badraoui, Afnan Elayyan Mousa Elayyan, Mohd Adnan, Adel Kadri, Emira Noumi
Thymus musilii Velen. Methanolic Extract: In Vitro and In Silico Screening of Its Antimicrobial, Antioxidant, Anti-Quorum Sensing, Antibiofilm, and Anticancer Activities. Life (Basel, Switzerland) 13 (1) (2022)
Iqrar Ahmad, Rahul H Pawara, Rukaiyya T Girase, Asama Y Pathan, Vilas R Jagatap, Nisheeth C Desai, Yusuf Oloruntoyin Ayipo, Sanjay J Surana, Harun M Patel
Synthesis, Molecular Modeling Study, and Quantum-Chemical-Based Investigations of Isoindoline-1,3-diones as Antimycobacterial Agents. ACS omega 7 (25) (2022)
Essmat M El-Sheref, Mohamed A Ameen, Kamal M El-Shaieb, Fathy F Abdel-Latif, Asmaa I Abdel-Naser, Alan B Brown, Stefan Bräse, Hazem M Fathy, Iqrar Ahmad Ansari, Harun M Patel, Hesham A M Gomaa, Bahaa G M Youssif, Asmaa H Mohamed
Design, Synthesis and Biological Evaluation of Syn and Anti -like Double Warhead Quinolinones Bearing Dihydroxy Naphthalene Moiety as Epidermal Growth Factor Receptor Inhibitors with Potential Apoptotic Antiproliferative Action. Molecules (Basel, Switzerland) 27 (24) (2022)
Yusuf Oloruntoyin Ayipo, Iqrar Ahmad Ansari, Waleed A Alananzeh, Amudat Lawal, Harun M Patel, Mohd Nizam Mordi
Computational modelling of potential Zn-sensitive non-β-lactam inhibitors of imipenemase-1 (IMP-1). Journal of biomolecular structure & dynamics (2022)
Yusuf Oloruntoyin Ayipo, Iqrar Ahmad Ansari, Najib Yahaya Sani, Sikirat Kehinde Sheu, Harun M Patel, Mohd Nizam Mordi
Molecular modelling and structure-activity relationship of a natural derivative of o -hydroxybenzoate as a potent inhibitor of dual NSP3 and NSP12 of SARS-CoV-2: in silico study. Journal of biomolecular structure & dynamics (2022)
Emira Noumi, Iqrar Ahmad Ansari, Nouha Bouali, Harun M Patel, Siwar Ghannay, Ayshah Aysh ALrashidi, Mohammad A Abdulhakeem, Mitesh Patel, Ozgur Ceylan, Riadh Badraoui, Afnan Elayyan Mousa Elayyan, Mohd Adnan, Adel Kadri, Emira Noumi
Thymus musilii Velen. Methanolic Extract: In Vitro and In Silico Screening of Its Antimicrobial, Antioxidant, Anti-Quorum Sensing, Antibiofilm, and Anticancer Activities. Life (Basel, Switzerland) 13 (1) (2022)
Derya Osmani Ye, Iqrar Ahmad Ansari, Begüm Nurpelin Sağlık Özkan, Serkan Levent, Harun M Patel, Özlem Atlı Eklioğlu, Zafer Asım Kaplancıklı
Design, synthesis and molecular docking and ADME studies of novel hydrazone derivatives for AChE inhibitory, BBB permeability and antioxidant effects. Journal of biomolecular structure & dynamics (2022)
Yassir Boulaamane, Iqrar Ahmad Ansari, Harun M Patel, Niloy Das, Mohammed Reda Britel, Amal Maurady
Structural exploration of selected C6 and C7-substituted coumarin isomers as selective MAO-B inhibitors. Journal of biomolecular structure & dynamics (2022)
Essmat M El-Sheref, Mohamed A Ameen, Kamal M El-Shaieb, Fathy F Abdel-Latif, Asmaa I Abdel-Naser, Alan B Brown, Stefan Bräse, Hazem M Fathy, Iqrar Ahmad Ansari, Harun M Patel, Hesham A M Gomaa, Bahaa G M Youssif, Asmaa H Mohamed
Design, Synthesis and Biological Evaluation of Syn and Anti -like Double Warhead Quinolinones Bearing Dihydroxy Naphthalene Moiety as Epidermal Growth Factor Receptor Inhibitors with Potential Apoptotic Antiproliferative Action. Molecules (Basel, Switzerland) 27 (24) (2022)
Babatomiwa Kikiowo, Iqrar Ahmad Ansari, Adebowale A Alade, Taiwo T Ijatuyi, Opeyemi Iwaloye, Harun M Patel
Molecular dynamics simulation and pharmacokinetics studies of ombuin and quercetin against human pancreatic α-amylase. Journal of biomolecular structure & dynamics (2022)
Essmat M El-Sheref, Mohamed A Ameen, Kamal M El-Shaieb, Fathy F Abdel-Latif, Asmaa I Abdel-Naser, Alan B Brown, Stefan Bräse, Hazem M Fathy, Iqrar Ahmad Ansari, Harun M Patel, Hesham A M Gomaa, Bahaa G M Youssif, Asmaa H Mohamed
Design, Synthesis and Biological Evaluation of Syn and Anti -like Double Warhead Quinolinones Bearing Dihydroxy Naphthalene Moiety as Epidermal Growth Factor Receptor Inhibitors with Potential Apoptotic Antiproliferative Action. Molecules (Basel, Switzerland) 27 (24) (2022)
Akaninyene D Udoikono, Ernest C Agwamba, Hitler Louis, Innocent Benjamin, Iqrar Ahmad Ansari, Emmanuel U Ejiofor, Eze F Ahuekwe, Kelechi Chukwuemeka, Adedapo S Adeyinka, Harun M Patel, Amanda-Lee Manicum, Moses Edim
Anti-inflammatory biomolecular activity of chlorinated-phenyldiazenyl-naphthalene-2-sulfonic acid derivatives: perception from DFT, molecular docking, and molecular dynamic simulation. Journal of biomolecular structure & dynamics (2022)
Nouha Bouali, Manel Ben Hammouda, Iqrar Ahmad Ansari, Siwar Ghannay, Amira Thouri, Amal Dbeibia, Harun M Patel, Walid Sabri Hamadou, Karim Hosni, Emira Noumi, Mohd Adnan, M D Imtaiyaz Hassan, Emira Noumi, Kaïss Aouadi, Adel Kadri
Multifunctional Derivatives of Spiropyrrolidine Tethered Indeno-Quinoxaline Heterocyclic Hybrids as Potent Antimicrobial, Antioxidant and Antidiabetic Agents: Design, Synthesis, In Vitro and In Silico Approaches. Molecules (Basel, Switzerland) 27 (21) (2022)
Essmat M El-Sheref, Mohamed A Ameen, Kamal M El-Shaieb, Fathy F Abdel-Latif, Asmaa I Abdel-Naser, Alan B Brown, Stefan Bräse, Hazem M Fathy, Iqrar Ahmad Ansari, Harun M Patel, Hesham A M Gomaa, Bahaa G M Youssif, Asmaa H Mohamed
Design, Synthesis and Biological Evaluation of Syn and Anti -like Double Warhead Quinolinones Bearing Dihydroxy Naphthalene Moiety as Epidermal Growth Factor Receptor Inhibitors with Potential Apoptotic Antiproliferative Action. Molecules (Basel, Switzerland) 27 (24) (2022)
Yusuf Oloruntoyin Ayipo, Waleed A Alananzeh, Iqrar Ahmad Ansari, Harun M Patel, Mohd Nizam Mordi
Structural modelling and in silico pharmacology of β-carboline alkaloids as potent 5-HT1A receptor antagonists and reuptake inhibitors. Journal of biomolecular structure & dynamics (2022)
Suliman Abdallah Alsagaby, Danish Iqbal, Iqrar Ahmad Ansari, Harun M Patel, Shabir Ahmad Mir, Yahya Awaji Madkhali, Atif Abdulwahab A Oyouni, Yousef M Hawsawi, Fahad A Alhumaydhi, Bader Alshehri, Wael Alturaiki, Bader Alanazi, Manzoor Ahmad Mir, Waleed Al Abdulmonem
In silico investigations identified Butyl Xanalterate to competently target CK2α (CSNK2A1) for therapy of chronic lymphocytic leukemia. Scientific reports 12 (1) (2022)
Emira Noumi, Iqrar Ahmad Ansari, Nouha Bouali, Harun M Patel, Siwar Ghannay, Ayshah Aysh ALrashidi, Mohammad A Abdulhakeem, Mitesh Patel, Ozgur Ceylan, Riadh Badraoui, Afnan Elayyan Mousa Elayyan, Mohd Adnan, Adel Kadri, Emira Noumi
Thymus musilii Velen. Methanolic Extract: In Vitro and In Silico Screening of Its Antimicrobial, Antioxidant, Anti-Quorum Sensing, Antibiofilm, and Anticancer Activities. Life (Basel, Switzerland) 13 (1) (2022)
Babatomiwa Kikiowo, Iqrar Ahmad Ansari, Adebowale A Alade, Taiwo T Ijatuyi, Opeyemi Iwaloye, Harun M Patel
Molecular dynamics simulation and pharmacokinetics studies of ombuin and quercetin against human pancreatic α-amylase. Journal of biomolecular structure & dynamics (2022)
Essmat M El-Sheref, Mohamed A Ameen, Kamal M El-Shaieb, Fathy F Abdel-Latif, Asmaa I Abdel-Naser, Alan B Brown, Stefan Bräse, Hazem M Fathy, Iqrar Ahmad Ansari, Harun M Patel, Hesham A M Gomaa, Bahaa G M Youssif, Asmaa H Mohamed
Design, Synthesis and Biological Evaluation of Syn and Anti -like Double Warhead Quinolinones Bearing Dihydroxy Naphthalene Moiety as Epidermal Growth Factor Receptor Inhibitors with Potential Apoptotic Antiproliferative Action. Molecules (Basel, Switzerland) 27 (24) (2022)
Essmat M El-Sheref, Mohamed A Ameen, Kamal M El-Shaieb, Fathy F Abdel-Latif, Asmaa I Abdel-Naser, Alan B Brown, Stefan Bräse, Hazem M Fathy, Iqrar Ahmad Ansari, Harun M Patel, Hesham A M Gomaa, Bahaa G M Youssif, Asmaa H Mohamed
Design, Synthesis and Biological Evaluation of Syn and Anti -like Double Warhead Quinolinones Bearing Dihydroxy Naphthalene Moiety as Epidermal Growth Factor Receptor Inhibitors with Potential Apoptotic Antiproliferative Action. Molecules (Basel, Switzerland) 27 (24) (2022)
R Girase, Iqrar Ahmad Ansari, R Pawara, Harun M Patel
Optimizing cardio, hepato and phospholipidosis toxicity of the Bedaquiline by chemoinformatics and molecular modelling approach. SAR and QSAR in environmental research 33 (3) (2022)
Bijo Mathew, Veerasamy Ravichandran, Seenivasan Raghuraman, T M Rangarajan, Mohamed A Abdelgawad, Iqrar Ahmad Ansari, Harun M Patel, Hoon Kim
Two dimensional-QSAR and molecular dynamics studies of a selected class of aldoxime- and hydroxy-functionalized chalcones as monoamine oxidase-B inhibitors. Journal of biomolecular structure & dynamics (2022)
Ulviye Acar Çevik, İsmail Çelik, Ayşen Işık, Iqrar Ahmad Ansari, Harun M Patel, Özlem Atlı Eklioğlu, Zafer Asım Kaplancıklı
Design, synthesis, molecular modeling, DFT, ADME and biological evaluation studies of some new 1,3,4-oxadiazole linked benzimidazoles as anticancer agents and aromatase inhibitors. Journal of biomolecular structure & dynamics (2022)
Yusuf Oloruntoyin Ayipo, Najib Yahaya Sani, Halimah Funmilayo Babamale, Iqrar Ahmad Ansari, Harun M Patel, Mohd Nizam Mordi
β-Carboline alkaloids induce structural plasticity and inhibition of SARS-CoV-2 nsp3 macrodomain more potently than remdesivir metabolite GS-441524: computational approach. Turkish journal of biology = Turk biyoloji dergisi 45 (4) (2021)
Matin Shaikh, Yashodeep Shinde, Rahul Pawara, Malleshappa Noolvi, Sanjay Surana, Iqrar Ahmad, Harun M Patel
Emerging Approaches to Overcome Acquired Drug Resistance Obstacles to Osimertinib in Non-Small-Cell Lung Cancer. Journal of medicinal chemistry (2021)
Iqrar Ahmad Ansari, Dileep Kumar, Harun M Patel
Computational investigation of phytochemicals from Withania somnifera (Indian ginseng/ashwagandha) as plausible inhibitors of GluN2B-containing NMDA receptors. Journal of biomolecular structure & dynamics (2021)
Iqrar Ahmad, Harsha Jadhav, Yashodeep Shinde, Vilas Jagtap, Rukaiyya Girase, Harun M Patel
Optimizing Bedaquiline for cardiotoxicity by structure based virtual screening, DFT analysis and molecular dynamic simulation studies to identify selective MDR-TB inhibitors. In silico pharmacology 9 (1) (2021)
Rahul Pawara, Iqrar Ahmad, Sanjay Surana, Harun M Patel
Computational identification of 2,4-disubstituted amino-pyrimidines as L858R/T790M-EGFR double mutant inhibitors using pharmacophore mapping, molecular docking, binding free energy calculation, DFT study and molecular dynamic simulation. In silico pharmacology 9 (1) (2021)
Harun M Patel, Mahesh Palkar, Rajshekhar Karpoormath
Exploring MDR-TB Inhibitory Potential of 4-Aminoquinazolines as Mycobacterium tuberculosis N-Acetylglucosamine-1-Phosphate Uridyltransferase (GlmUMTB ) Inhibitors. Chemistry & biodiversity 17 (8) (2020)