Bahaa G M Youssif

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 53

Top Venues

Molecules (Basel, Switzerland)

Pharmaceuticals (Basel, Switzerland)

Archiv der Pharmazie

Chemical biology & drug design

Assiut University (PHD)

This page only lists publications with an associated author ORCID identifier.

Education History

Assiut University Feb 10 2012

Egypt

PHD :: Pharmaceutical Organic Chemistry Department

Publications

Lamya H Al-Wahaibi, Mostafa H Abdel-Rahman, Khaled El-Adl, Bahaa G M Youssif, Stefan Bräse, Salah A Abdel-Aziz
New Diaryl-1,2,4-triazolo[3,4- a ]pyrimidine Hybrids as Selective COX-2/sEH Dual Inhibitors with Potent Analgesic/Anti-inflammatory and Cardioprotective Properties. ACS omega 9 (31) (2024)
Lamya H Al-Wahaibi, Ali M Elshamsy, Taha F S Ali, Bahaa G M Youssif, Stefan Bräse, Mohamed Abdel-Aziz, Nawal A El-Koussi
Design and Synthesis of New Dihydropyrimidine Derivatives with a Cytotoxic Effect as Dual EGFR/VEGFR-2 Inhibitors. ACS omega 9 (32) (2024)
Bahaa G M Youssif, Martha M Morcoss, Stefan Bräse, Mohamed Abdel-Aziz, Hamdy M Abdel-Rahman, Dalal A Abou El-Ella, El Shimaa M N Abdelhafez
Benzimidazole-Based Derivatives as Apoptotic Antiproliferative Agents: Design, Synthesis, Docking, and Mechanistic Studies. Molecules (Basel, Switzerland) 29 (2) (2024)
Bahaa G M Youssif, Martha M Morcoss, Stefan Bräse, Mohamed Abdel-Aziz, Hamdy M Abdel-Rahman, Dalal A Abou El-Ella, El Shimaa M N Abdelhafez
Benzimidazole-Based Derivatives as Apoptotic Antiproliferative Agents: Design, Synthesis, Docking, and Mechanistic Studies. Molecules (Basel, Switzerland) 29 (2) (2024)
Frias Obaid Arhema Frejat, Bingbing Zhao, Nooruldeen Furaijit, Lihong Wang, Hesham A Abou-Zied, Hazem M Fathy, Fatma A M Mohamed, Bahaa G M Youssif, Chunli Wu
New pyrrolidine-carboxamide derivatives as dual antiproliferative EGFR/CDK2 inhibitors. Chemical biology & drug design 103 (1) (2024)
Lamya H Al-Wahaibi, Bahaa G M Youssif, Hesham A Abou-Zied, Stefan Bräse, Alan B Brown, Hendawy N Tawfeek, Essmat M El-Sheref
Synthesis of a new series of 4-pyrazolylquinolinones with apoptotic antiproliferative effects as dual EGFR/BRAF V600E inhibitors. RSC medicinal chemistry 15 (7) (2024)
Hendawy N Tawfeek, Alshaimaa Abdelmoez, Kholood A Dahlous, Bahaa G M Youssif, Stefan Bräse, Kari T Rissanen, Martin Nieger, Essmat M El-Sheref
Convenient synthesis and X-ray determination of 2-amino-6 H -1,3,4-thiadiazin-3-ium bromides endowed with antiproliferative activity. RSC advances 14 (25) (2024)
Lamya H Al-Wahaibi, Bahaa G M Youssif, Hesham A Abou-Zied, Stefan Bräse, Alan B Brown, Hendawy N Tawfeek, Essmat M El-Sheref
Synthesis of a new series of 4-pyrazolylquinolinones with apoptotic antiproliferative effects as dual EGFR/BRAF V600E inhibitors. RSC medicinal chemistry 15 (7) (2024)
Hendawy N Tawfeek, Alshaimaa Abdelmoez, Kholood A Dahlous, Bahaa G M Youssif, Stefan Bräse, Kari T Rissanen, Martin Nieger, Essmat M El-Sheref
Convenient synthesis and X-ray determination of 2-amino-6 H -1,3,4-thiadiazin-3-ium bromides endowed with antiproliferative activity. RSC advances 14 (25) (2024)
Lamya H Al-Wahaibi, Ali M Elshamsy, Taha F S Ali, Bahaa G M Youssif, Stefan Bräse, Mohamed Abdel-Aziz, Nawal A El-Koussi
Design and Synthesis of New Dihydropyrimidine Derivatives with a Cytotoxic Effect as Dual EGFR/VEGFR-2 Inhibitors. ACS omega 9 (32) (2024)
Lamya H Al-Wahaibi, Mostafa H Abdel-Rahman, Khaled El-Adl, Bahaa G M Youssif, Stefan Bräse, Salah A Abdel-Aziz
New Diaryl-1,2,4-triazolo[3,4- a ]pyrimidine Hybrids as Selective COX-2/sEH Dual Inhibitors with Potent Analgesic/Anti-inflammatory and Cardioprotective Properties. ACS omega 9 (31) (2024)
Bahaa G M Youssif, Martha M Morcoss, Stefan Bräse, Mohamed Abdel-Aziz, Hamdy M Abdel-Rahman, Dalal A Abou El-Ella, El Shimaa M N Abdelhafez
Benzimidazole-Based Derivatives as Apoptotic Antiproliferative Agents: Design, Synthesis, Docking, and Mechanistic Studies. Molecules (Basel, Switzerland) 29 (2) (2024)
Frias Obaid Arhema Frejat, Bingbing Zhao, Nooruldeen Furaijit, Lihong Wang, Hesham A Abou-Zied, Hazem M Fathy, Fatma A M Mohamed, Bahaa G M Youssif, Chunli Wu
New pyrrolidine-carboxamide derivatives as dual antiproliferative EGFR/CDK2 inhibitors. Chemical biology & drug design 103 (1) (2024)
Bahaa G M Youssif, Martha M Morcoss, Stefan Bräse, Mohamed Abdel-Aziz, Hamdy M Abdel-Rahman, Dalal A Abou El-Ella, El Shimaa M N Abdelhafez
Benzimidazole-Based Derivatives as Apoptotic Antiproliferative Agents: Design, Synthesis, Docking, and Mechanistic Studies. Molecules (Basel, Switzerland) 29 (2) (2024)
Essmat M El-Sheref, Stefan Bräse, Hendawy N Tawfeek, Fatmah Ali S Alasmary, Bahaa G M Youssif
Synthesis, Antioxidant and Antiproliferative Actions of 4-(1,2,3-Triazol-1-yl)quinolin-2(1 H )-ones as Multi-Target Inhibitors. International journal of molecular sciences 24 (17) (2023)
Mohamed T-E Maghraby, Tahani Mazyad Almutairi, Stefan Bräse, Ola I A Salem, Bahaa G M Youssif, Mahmoud M Sheha
New 1,2,3-Triazole/1,2,4-triazole Hybrids as Aromatase Inhibitors: Design, Synthesis, and Apoptotic Antiproliferative Activity. Molecules (Basel, Switzerland) 28 (20) (2023)
Alaa A Hassan, Nasr K Mohamed, Ashraf A Aly, Mohamed Ramadan, Hesham A M Gomaa, Ahmed T Abdel-Aziz, Bahaa G M Youssif, Stefan Bräse, Oliver Fuhr
Synthesis and Antiproliferative Potential of Thiazole and 4-Thiazolidinone Containing Motifs as Dual Inhibitors of EGFR and BRAF V600E . Molecules (Basel, Switzerland) 28 (24) (2023)
Lamya H Al-Wahaibi, Hesham A Abou-Zied, Mohamed Hisham, Eman A M Beshr, Bahaa G M Youssif, Stefan Bräse, Alaa M Hayallah, Mohamed Abdel-Aziz
Design, Synthesis, and Biological Evaluation of Novel 3-Cyanopyridone/Pyrazoline Hybrids as Potential Apoptotic Antiproliferative Agents Targeting EGFR/BRAF V600E Inhibitory Pathways. Molecules (Basel, Switzerland) 28 (18) (2023)
Lamya H Al-Wahaibi, Essmat M El-Sheref, Mohamed M Hammouda, Bahaa G M Youssif
One-Pot Synthesis of 1-Thia-4-azaspiro[4.4/5]alkan-3-ones via Schiff Base: Design, Synthesis, and Apoptotic Antiproliferative Properties of Dual EGFR/BRAF V600E Inhibitors. Pharmaceuticals (Basel, Switzerland) 16 (3) (2023)
Lamya H Al-Wahaibi, Anber F Mohammed, Mostafa H Abdelrahman, Laurent Trembleau, Bahaa G M Youssif
Design, Synthesis, and Antiproliferative Activity of New 5-Chloro-indole-2-carboxylate and Pyrrolo[3,4- b ]indol-3-one Derivatives as Potent Inhibitors of EGFR T790M /BRAF V600E Pathways. Molecules (Basel, Switzerland) 28 (3) (2023)
Alaa A Hassan, Nasr K Mohamed, Ashraf A Aly, Mohamed Ramadan, Hesham A M Gomaa, Ahmed T Abdel-Aziz, Bahaa G M Youssif, Stefan Bräse, Oliver Fuhr
Synthesis and Antiproliferative Potential of Thiazole and 4-Thiazolidinone Containing Motifs as Dual Inhibitors of EGFR and BRAF V600E . Molecules (Basel, Switzerland) 28 (24) (2023)
Lamya H Al-Wahaibi, Anber F Mohammed, Mostafa H Abdelrahman, Laurent Trembleau, Bahaa G M Youssif
Design, Synthesis, and Antiproliferative Activity of New 5-Chloro-indole-2-carboxylate and Pyrrolo[3,4- b ]indol-3-one Derivatives as Potent Inhibitors of EGFR T790M /BRAF V600E Pathways. Molecules (Basel, Switzerland) 28 (3) (2023)
Lamya H Al-Wahaibi, Essmat M El-Sheref, Mohamed M Hammouda, Bahaa G M Youssif
One-Pot Synthesis of 1-Thia-4-azaspiro[4.4/5]alkan-3-ones via Schiff Base: Design, Synthesis, and Apoptotic Antiproliferative Properties of Dual EGFR/BRAF V600E Inhibitors. Pharmaceuticals (Basel, Switzerland) 16 (3) (2023)
Fatma A M Mohamed, Saleha Y M Alakilli, Eman Fawzy El Azab, Faris A M Baawad, Esraa Ibrahim A Shaaban, Heba Abu Alrub, Omnia Hendawy, Hesham A M Gomaa, Adel G Bakr, Mostafa H Abdelrahman, Laurent Trembleau, Anber F Mohammed, Bahaa G M Youssif
Discovery of new 5-substituted-indole-2-carboxamides as dual epidermal growth factor receptor (EGFR)/cyclin dependent kinase-2 (CDK2) inhibitors with potent antiproliferative action. RSC medicinal chemistry 14 (4) (2023)
Lamya H Al-Wahaibi, Anber F Mohammed, Mostafa H Abdelrahman, Laurent Trembleau, Bahaa G M Youssif
Design, Synthesis, and Antiproliferative Activity of New 5-Chloro-indole-2-carboxylate and Pyrrolo[3,4- b ]indol-3-one Derivatives as Potent Inhibitors of EGFR T790M /BRAF V600E Pathways. Molecules (Basel, Switzerland) 28 (3) (2023)
Lamya H Al-Wahaibi, Essmat M El-Sheref, Alaa A Hassan, Stefan Bräse, M Nieger, Bahaa G M Youssif, Mahmoud A A Ibrahim, Hendawy N Tawfeek
Synthesis and Structure Determination of Substituted Thiazole Derivatives as EGFR/BRAF V600E Dual Inhibitors Endowed with Antiproliferative Activity. Pharmaceuticals (Basel, Switzerland) 16 (7) (2023)
Lamya H Al-Wahaibi, Essmat M El-Sheref, Mohamed M Hammouda, Bahaa G M Youssif
One-Pot Synthesis of 1-Thia-4-azaspiro[4.4/5]alkan-3-ones via Schiff Base: Design, Synthesis, and Apoptotic Antiproliferative Properties of Dual EGFR/BRAF V600E Inhibitors. Pharmaceuticals (Basel, Switzerland) 16 (3) (2023)
Lamya H Al-Wahaibi, Anber F Mohammed, Mostafa H Abdelrahman, Laurent Trembleau, Bahaa G M Youssif
Design, Synthesis, and Biological Evaluation of Indole-2-carboxamides as Potential Multi-Target Antiproliferative Agents. Pharmaceuticals (Basel, Switzerland) 16 (7) (2023)
Fatma A M Mohamed, Saleha Y M Alakilli, Eman Fawzy El Azab, Faris A M Baawad, Esraa Ibrahim A Shaaban, Heba Abu Alrub, Omnia Hendawy, Hesham A M Gomaa, Adel G Bakr, Mostafa H Abdelrahman, Laurent Trembleau, Anber F Mohammed, Bahaa G M Youssif
Discovery of new 5-substituted-indole-2-carboxamides as dual epidermal growth factor receptor (EGFR)/cyclin dependent kinase-2 (CDK2) inhibitors with potent antiproliferative action. RSC medicinal chemistry 14 (4) (2023)
Lamya H Al-Wahaibi, Anber F Mohammed, Mostafa H Abdelrahman, Laurent Trembleau, Bahaa G M Youssif
Design, Synthesis, and Antiproliferative Activity of New 5-Chloro-indole-2-carboxylate and Pyrrolo[3,4- b ]indol-3-one Derivatives as Potent Inhibitors of EGFR T790M /BRAF V600E Pathways. Molecules (Basel, Switzerland) 28 (3) (2023)
Fatma Fouad Hagar, Samar H Abbas, Dalia Abdelhamid, Hesham A M Gomaa, Bahaa G M Youssif, Mohamed Abdel-Aziz
New 1,3,4-oxadiazole-chalcone/benzimidazole hybrids as potent antiproliferative agents. Archiv der Pharmazie (2022)
Mohamed T-E Maghraby, Ola I A Salem, Bahaa G M Youssif, Mahmoud M Sheha
Design, synthesis, and modelling study of new 1,2,3-triazole/chalcone hybrids with antiproliferative action as EGFR inhibitors. Chemical biology & drug design (2022)
Essmat M El-Sheref, Mohamed A Ameen, Kamal M El-Shaieb, Fathy F Abdel-Latif, Asmaa I Abdel-Naser, Alan B Brown, Stefan Bräse, Hazem M Fathy, Iqrar Ahmad Ansari, Harun M Patel, Hesham A M Gomaa, Bahaa G M Youssif, Asmaa H Mohamed
Design, Synthesis and Biological Evaluation of Syn and Anti -like Double Warhead Quinolinones Bearing Dihydroxy Naphthalene Moiety as Epidermal Growth Factor Receptor Inhibitors with Potential Apoptotic Antiproliferative Action. Molecules (Basel, Switzerland) 27 (24) (2022)
Mohamed A Mahmoud, Anber F Mohammed, Ola I A Salem, Hesham A M Gomaa, Bahaa G M Youssif
New 1,3,4-oxadiazoles linked with the 1,2,3-triazole moiety as antiproliferative agents targeting the EGFR tyrosine kinase. Archiv der Pharmazie 355 (6) (2022)
Hesham A Abou-Zied, Eman A M Beshr, Hesham A M Gomaa, Yaser A Mostafa, Bahaa G M Youssif, Alaa M Hayallah, Mohamad Abdel-Aziz
Discovery of new cyanopyridine/chalcone hybrids as dual inhibitors of EGFR/BRAF V600E with promising antiproliferative properties. Archiv der Pharmazie (2022)
Lamya H Al-Wahaibi, Mohamed A Mahmoud, Yaser A Mostafa, Ali E Raslan, Bahaa G M Youssif
Novel piperine-carboximidamide hybrids: design, synthesis, and antiproliferative activity via a multi-targeted inhibitory pathway. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2022)
Essmat M El-Sheref, Mohamed A Ameen, Kamal M El-Shaieb, Fathy F Abdel-Latif, Asmaa I Abdel-Naser, Alan B Brown, Stefan Bräse, Hazem M Fathy, Iqrar Ahmad Ansari, Harun M Patel, Hesham A M Gomaa, Bahaa G M Youssif, Asmaa H Mohamed
Design, Synthesis and Biological Evaluation of Syn and Anti -like Double Warhead Quinolinones Bearing Dihydroxy Naphthalene Moiety as Epidermal Growth Factor Receptor Inhibitors with Potential Apoptotic Antiproliferative Action. Molecules (Basel, Switzerland) 27 (24) (2022)
Essmat M El-Sheref, Mohamed A Ameen, Kamal M El-Shaieb, Fathy F Abdel-Latif, Asmaa I Abdel-Naser, Alan B Brown, Stefan Bräse, Hazem M Fathy, Iqrar Ahmad Ansari, Harun M Patel, Hesham A M Gomaa, Bahaa G M Youssif, Asmaa H Mohamed
Design, Synthesis and Biological Evaluation of Syn and Anti -like Double Warhead Quinolinones Bearing Dihydroxy Naphthalene Moiety as Epidermal Growth Factor Receptor Inhibitors with Potential Apoptotic Antiproliferative Action. Molecules (Basel, Switzerland) 27 (24) (2022)
Salah A Abdel-Aziz, Ehab S Taher, Ping Lan, Nawal A El-Koussi, Ola I A Salem, Hesham A M Gomaa, Bahaa G M Youssif
New pyrimidine/thiazole hybrids endowed with analgesic, anti-inflammatory, and lower cardiotoxic activities: Design, synthesis, and COX-2/sEH dual inhibition. Archiv der Pharmazie 355 (7) (2022)
Essmat M El-Sheref, Mohamed A Ameen, Kamal M El-Shaieb, Fathy F Abdel-Latif, Asmaa I Abdel-Naser, Alan B Brown, Stefan Bräse, Hazem M Fathy, Iqrar Ahmad Ansari, Harun M Patel, Hesham A M Gomaa, Bahaa G M Youssif, Asmaa H Mohamed
Design, Synthesis and Biological Evaluation of Syn and Anti -like Double Warhead Quinolinones Bearing Dihydroxy Naphthalene Moiety as Epidermal Growth Factor Receptor Inhibitors with Potential Apoptotic Antiproliferative Action. Molecules (Basel, Switzerland) 27 (24) (2022)
Firas O A Frejat, Yaquan Cao, Lihong Wang, Hongjin Zhai, Ahmed H Abdelazeem, Hesham A M Gomaa, Bahaa G M Youssif, Chunli Wu
New 1,2,4-oxadiazole/pyrrolidine hybrids as topoisomerase IV and DNA gyrase inhibitors with promising antibacterial activity. Archiv der Pharmazie 355 (7) (2022)
Essmat M El-Sheref, Mohamed A Ameen, Kamal M El-Shaieb, Fathy F Abdel-Latif, Asmaa I Abdel-Naser, Alan B Brown, Stefan Bräse, Hazem M Fathy, Iqrar Ahmad Ansari, Harun M Patel, Hesham A M Gomaa, Bahaa G M Youssif, Asmaa H Mohamed
Design, Synthesis and Biological Evaluation of Syn and Anti -like Double Warhead Quinolinones Bearing Dihydroxy Naphthalene Moiety as Epidermal Growth Factor Receptor Inhibitors with Potential Apoptotic Antiproliferative Action. Molecules (Basel, Switzerland) 27 (24) (2022)
Lamya H Al-Wahaibi, Yaser A Mostafa, Mostafa H Abdelrahman, Ali H El-Bahrawy, Laurent Trembleau, Bahaa G M Youssif
Synthesis and Biological Evaluation of Indole-2-Carboxamides with Potent Apoptotic Antiproliferative Activity as EGFR/CDK2 Dual Inhibitors. Pharmaceuticals (Basel, Switzerland) 15 (8) (2022)
Essmat M El-Sheref, Mohamed A Ameen, Kamal M El-Shaieb, Fathy F Abdel-Latif, Asmaa I Abdel-Naser, Alan B Brown, Stefan Bräse, Hazem M Fathy, Iqrar Ahmad Ansari, Harun M Patel, Hesham A M Gomaa, Bahaa G M Youssif, Asmaa H Mohamed
Design, Synthesis and Biological Evaluation of Syn and Anti -like Double Warhead Quinolinones Bearing Dihydroxy Naphthalene Moiety as Epidermal Growth Factor Receptor Inhibitors with Potential Apoptotic Antiproliferative Action. Molecules (Basel, Switzerland) 27 (24) (2022)
Essmat M El-Sheref, Mohammed A I Elbastawesy, Alan B Brown, Ahmed Mahmoud Shawky, Hesham A M Gomaa, Stefan Bräse, Bahaa G M Youssif
Design and Synthesis of (2-oxo-1,2-Dihydroquinolin-4-yl)-1,2,3-triazole Derivatives via Click Reaction: Potential Apoptotic Antiproliferative Agents. Molecules (Basel, Switzerland) 26 (22) (2021)
Ahmed H Tantawy, Xiang-Gao Meng, Adel A Marzouk, Ali Fouad, Ahmed H Abdelazeem, Bahaa G M Youssif, Hong Jiang, Man-Qun Wang
Structure-based design, synthesis, and biological evaluation of novel piperine-resveratrol hybrids as antiproliferative agents targeting SIRT-2. RSC advances 11 (41) (2021)
Mohammad A S Abourehab, Alaa M Alqahtani, Bahaa G M Youssif, Ahmed M Gouda
Globally Approved EGFR Inhibitors: Insights into Their Syntheses, Target Kinases, Biological Activities, Receptor Interactions, and Metabolism. Molecules (Basel, Switzerland) 26 (21) (2021)
Lamya H Al-Wahaibi, Bahaa G M Youssif, Ehab S Taher, Ahmed H Abdelazeem, Antar A Abdelhamid, Adel A Marzouk
Design, Synthesis, Biological Evaluation, and Computational Studies of Novel Tri-Aryl Imidazole-Benzene Sulfonamide Hybrids as Promising Selective Carbonic Anhydrase IX and XII Inhibitors. Molecules (Basel, Switzerland) 26 (16) (2021)
Mohammad M Al-Sanea, Lizaveta Gotina, Mamdouh Fa Mohamed, Della Grace Thomas Parambi, Hesham A M Gomaa, Bijo Mathew, Bahaa G M Youssif, Khalid Saad Alharbi, Zainab M Elsayed, Mohamed Abdelwahab Abdelgawad, Wagdy M Eldehna
Design, Synthesis and Biological Evaluation of New HDAC1 and HDAC2 Inhibitors Endowed with Ligustrazine as a Novel Cap Moiety. Drug design, development and therapy 14 (2020)
Mahmoud S Abdelbaset, Mohamed Abdel-Aziz, Gamal El-Din A Abuo-Rahma, Mostafa H Abdelrahman, Mohamed Ramadan, Bahaa G M Youssif
Novel quinoline derivatives carrying nitrones/oximes nitric oxide donors: Design, synthesis, antiproliferative and caspase-3 activation activities. Archiv der Pharmazie 352 (1) (2018)
Mohammad M Al-Sanea, Mohammed Safwan Ali Khan, Ahmed Z Abdelazem, So Ha Lee, Pooi Ling Mok, Mohammed Gamal, Mohamed E Shaker, Muhammad Afzal, Bahaa G M Youssif, Nesreen Nabil Omar
Synthesis and In Vitro Antiproliferative Activity of New 1-Phenyl-3-(4-(pyridin-3-yl)phenyl)urea Scaffold-Based Compounds. Molecules (Basel, Switzerland) 23 (2) (2018)
Hua-Li Qin, Jing Leng, Bahaa G M Youssif, Muhammad Wahab Amjad, Maria Abdul Ghafoor Raja, Muhammad Ajaz Hussain, Zahid Hussain, Syeda Naveed Kazmi, Syed Nasir Abbas Bukhari
Synthesis and mechanistic studies of curcumin analog-based oximes as potential anticancer agents. Chemical biology & drug design 90 (3) (2017)
Mostafa H Abdelrahman, Ahmed S Aboraia, Bahaa G M Youssif, Bakheet E M Elsadek
Design, synthesis and pharmacophoric model building of new 3-alkoxymethyl/3-phenyl indole-2-carboxamides with potential antiproliferative activity. Chemical biology & drug design 90 (1) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Bahaa G M Youssif