Heather P Harding

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 27

Top Topics

Induced Apoptosis

Top Venues

The EMBO journal

Proceedings of the National Academy of Sciences of the United States of America

EMBO molecular medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Yahui Yan, Maithili Shetty, Heather P Harding, Ginto George, Alisa F Zyryanova, Katherine Labbé, Amirhossein Mafi, Qi Hao, Carmela Sidrauski, David Ron
Substrate recruitment via eIF2γ enhances catalytic efficiency of a holophosphatase that terminates the integrated stress response. Proceedings of the National Academy of Sciences of the United States of America 121 (14) (2024)
Yahui Yan, Maithili Shetty, Heather P Harding, Ginto George, Alisa F Zyryanova, Katherine Labbé, Amirhossein Mafi, Qi Hao, Carmela Sidrauski, David Ron
Substrate recruitment via eIF2γ enhances catalytic efficiency of a holophosphatase that terminates the integrated stress response. Proceedings of the National Academy of Sciences of the United States of America 121 (14) (2024)
Joanne Tung, Lei Huang, Ginto George, Heather P Harding, David Ron, Adriana Ordonez
A genome-wide CRISPR/Cas9 screen identifies calreticulin as a selective repressor of ATF6α. eLife 13 (2024)
Yahui Yan, Maithili Shetty, Heather P Harding, Ginto George, Alisa F Zyryanova, Katherine Labbé, Amirhossein Mafi, Qi Hao, Carmela Sidrauski, David Ron
Substrate recruitment via eIF2γ enhances catalytic efficiency of a holophosphatase that terminates the integrated stress response. Proceedings of the National Academy of Sciences of the United States of America 121 (14) (2024)
Joanne Tung, Lei Huang, Ginto George, Heather P Harding, David Ron, Adriana Ordonez
A genome-wide CRISPR/Cas9 screen identifies calreticulin as a selective repressor of ATF6α. eLife 13 (2024)
Yahui Yan, Maithili Shetty, Heather P Harding, Ginto George, Alisa F Zyryanova, Katherine Labbé, Amirhossein Mafi, Qi Hao, Carmela Sidrauski, David Ron
Substrate recruitment via eIF2γ enhances catalytic efficiency of a holophosphatase that terminates the integrated stress response. Proceedings of the National Academy of Sciences of the United States of America 121 (14) (2024)
Joanne Tung, Lei Huang, Ginto George, Heather P Harding, David Ron, Adriana Ordonez
A genome-wide CRISPR/Cas9 screen identifies calreticulin as a selective repressor of ATF6α. eLife 13 (2024)
Yahui Yan, Maithili Shetty, Heather P Harding, Ginto George, Alisa F Zyryanova, Katherine Labbé, Amirhossein Mafi, Qi Hao, Carmela Sidrauski, David Ron
Substrate recruitment via eIF2γ enhances catalytic efficiency of a holophosphatase that terminates the integrated stress response. Proceedings of the National Academy of Sciences of the United States of America 121 (14) (2024)
Joanne Tung, Lei Huang, Ginto George, Heather P Harding, David Ron, Adriana Ordonez
A genome-wide CRISPR/Cas9 screen identifies calreticulin as a selective repressor of ATF6α. eLife 13 (2024)
Lisa Neidhardt, Eva Cloots, Natalie Friemel, Caroline A M Weiss, Heather P Harding, Stephen H McLaughlin, Sophie Janssens, David Ron
The IRE1β-mediated unfolded protein response is repressed by the chaperone AGR2 in mucin producing cells. The EMBO journal (2023)
Lisa Neidhardt, Eva Cloots, Natalie Friemel, Caroline A M Weiss, Heather P Harding, Stephen H McLaughlin, Sophie Janssens, David Ron
The IRE1β-mediated unfolded protein response is repressed by the chaperone AGR2 in mucin producing cells. The EMBO journal (2023)
Luke A Perera, Andrew T Hattersley, Heather P Harding, Matthew N Wakeling, Sarah E Flanagan, Ibrahim Mohsina, Jamal Raza, Alice Gardham, David Ron, Elisa De Franco
Infancy-onset diabetes caused by de-regulated AMPylation of the human endoplasmic reticulum chaperone BiP. EMBO molecular medicine 15 (3) (2023)
Luke A Perera, Andrew T Hattersley, Heather P Harding, Matthew N Wakeling, Sarah E Flanagan, Ibrahim Mohsina, Jamal Raza, Alice Gardham, David Ron, Elisa De Franco
Infancy-onset diabetes caused by de-regulated AMPylation of the human endoplasmic reticulum chaperone BiP. EMBO molecular medicine (2023)
Lisa Neidhardt, Eva Cloots, Natalie Friemel, Caroline A M Weiss, Heather P Harding, Stephen H McLaughlin, Sophie Janssens, David Ron
The IRE1β-mediated unfolded protein response is repressed by the chaperone AGR2 in mucin producing cells. The EMBO journal (2023)
Lisa Neidhardt, Eva Cloots, Natalie Friemel, Caroline A M Weiss, Heather P Harding, Stephen H McLaughlin, Sophie Janssens, David Ron
The IRE1β-mediated unfolded protein response is repressed by the chaperone AGR2 in mucin producing cells. The EMBO journal 43 (5) (2023)
Luke A Perera, Andrew T Hattersley, Heather P Harding, Matthew N Wakeling, Sarah E Flanagan, Ibrahim Mohsina, Jamal Raza, Alice Gardham, David Ron, Elisa De Franco
Infancy-onset diabetes caused by de-regulated AMPylation of the human endoplasmic reticulum chaperone BiP. EMBO molecular medicine 15 (3) (2023)
Lisa Neidhardt, Eva Cloots, Natalie Friemel, Caroline A M Weiss, Heather P Harding, Stephen H McLaughlin, Sophie Janssens, David Ron
The IRE1β-mediated unfolded protein response is repressed by the chaperone AGR2 in mucin producing cells. The EMBO journal 43 (5) (2023)
Luke A Perera, Andrew T Hattersley, Heather P Harding, Matthew N Wakeling, Sarah E Flanagan, Ibrahim Mohsina, Jamal Raza, Alice Gardham, David Ron, Elisa De Franco
Infancy-onset diabetes caused by de-regulated AMPylation of the human endoplasmic reticulum chaperone BiP. EMBO molecular medicine 15 (3) (2023)
Luke A Perera, Andrew T Hattersley, Heather P Harding, Matthew N Wakeling, Sarah E Flanagan, Ibrahim Mohsina, Jamal Raza, Alice Gardham, David Ron, Elisa De Franco
Infancy-onset diabetes caused by de-regulated AMPylation of the human endoplasmic reticulum chaperone BiP. EMBO molecular medicine 15 (3) (2023)
Lisa Neidhardt, Eva Cloots, Natalie Friemel, Caroline A M Weiss, Heather P Harding, Stephen H McLaughlin, Sophie Janssens, David Ron
The IRE1β-mediated unfolded protein response is repressed by the chaperone AGR2 in mucin producing cells. The EMBO journal (2023)
Lisa Neidhardt, Eva Cloots, Natalie Friemel, Caroline A M Weiss, Heather P Harding, Stephen H McLaughlin, Sophie Janssens, David Ron
The IRE1β-mediated unfolded protein response is repressed by the chaperone AGR2 in mucin producing cells. The EMBO journal 43 (5) (2023)
Lisa Neidhardt, Eva Cloots, Natalie Friemel, Caroline A M Weiss, Heather P Harding, Stephen H McLaughlin, Sophie Janssens, David Ron
The IRE1β-mediated unfolded protein response is repressed by the chaperone AGR2 in mucin producing cells. The EMBO journal 43 (5) (2023)
Yahui Yan, Heather P Harding, David Ron
Higher-order phosphatase-substrate contacts terminate the integrated stress response. Nature structural & molecular biology 28 (10) (2021)
Heather P Harding, Adriana Ordonez, Felicity Allen, Leopold Parts, Alison J Inglis, Roger L Williams, David Ron
The ribosomal P-stalk couples amino acid starvation to GCN2 activation in mammalian cells. eLife 8 (2019)
Alisa F Zyryanova, Felix Weis, Alexandre Faille, Akeel Abo Alard, Ana Crespillo-Casado, Yusuke Sekine, Heather P Harding, Felicity Allen, Leopold Parts, Christophe Fromont, Peter M Fischer, Alan John Warren, David Ron
Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B. Science (New York, N.Y.) 359 (6383) (2018)
Markus Tschurtschenthaler, Timon E Adolph, Jonathan W Ashcroft, Lukas Niederreiter, Richa Bharti, Svetlana Saveljeva, Joya Bhattacharyya, Magdalena B Flak, David Q Shih, Gwenny M Fuhler, Miles Parkes, Kenji Kohno, Takao Iwawaki, Christien J van der Woude, Heather P Harding, Andrew Mark Smith, Maikel Petrus Peppelenbosch, Stephan R Targan, David Ron, Philip C Rosenstiel, Richard S Blumberg, Arthur Kaser
Defective ATG16L1-mediated removal of IRE1α drives Crohn's disease-like ileitis. The Journal of experimental medicine 214 (2) (2017)
Yusuke Sekine, Alisa F Zyryanova, Ana Crespillo-Casado, Niko Amin-Wetzel, Heather P Harding, David Ron
Paradoxical Sensitivity to an Integrated Stress Response Blocking Mutation in Vanishing White Matter Cells. PloS one 11 (11) (2016)
Yifeng Lin, Xiaosha Pang, Guangcun Huang, Stephanie Jamison, Jingye Fang, Heather P Harding, David Ron, Wensheng Lin
Impaired eukaryotic translation initiation factor 2B activity specifically in oligodendrocytes reproduces the pathology of vanishing white matter disease in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience 34 (36) (2014)