Amirhossein Mafi

ORCID

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 18

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Communications chemistry

QRB discovery

Nature chemical biology

California Institute of Technology

University of British Columbia (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

California Institute of Technology Apr 01 2018

United States

Posdoc scholar :: Chemistry

Education History

University of British Columbia Jan 01 2014 - Feb 22 2018

Canada

PHD :: Chemical and Biological Engineering

Publications

Yahui Yan, Maithili Shetty, Heather P Harding, Ginto George, Alisa F Zyryanova, Katherine Labbé, Amirhossein Mafi, Qi Hao, Carmela Sidrauski, David Ron
Substrate recruitment via eIF2γ enhances catalytic efficiency of a holophosphatase that terminates the integrated stress response. Proceedings of the National Academy of Sciences of the United States of America 121 (14) (2024)
Yahui Yan, Maithili Shetty, Heather P Harding, Ginto George, Alisa F Zyryanova, Katherine Labbé, Amirhossein Mafi, Qi Hao, Carmela Sidrauski, David Ron
Substrate recruitment via eIF2γ enhances catalytic efficiency of a holophosphatase that terminates the integrated stress response. Proceedings of the National Academy of Sciences of the United States of America 121 (14) (2024)
Yahui Yan, Maithili Shetty, Heather P Harding, Ginto George, Alisa F Zyryanova, Katherine Labbé, Amirhossein Mafi, Qi Hao, Carmela Sidrauski, David Ron
Substrate recruitment via eIF2γ enhances catalytic efficiency of a holophosphatase that terminates the integrated stress response. Proceedings of the National Academy of Sciences of the United States of America 121 (14) (2024)
Yahui Yan, Maithili Shetty, Heather P Harding, Ginto George, Alisa F Zyryanova, Katherine Labbé, Amirhossein Mafi, Qi Hao, Carmela Sidrauski, David Ron
Substrate recruitment via eIF2γ enhances catalytic efficiency of a holophosphatase that terminates the integrated stress response. Proceedings of the National Academy of Sciences of the United States of America 121 (14) (2024)
Yahui Yan, Maithili Shetty, Heather P Harding, Ginto George, Alisa F Zyryanova, Katherine Labbé, Amirhossein Mafi, Qi Hao, Carmela Sidrauski, David Ron
Substrate recruitment via eIF2γ enhances catalytic efficiency of a holophosphatase that terminates the integrated stress response. Proceedings of the National Academy of Sciences of the United States of America 121 (14) (2024)
Arundhati Nag, Amirhossein Mafi, Samir Das, Mary Beth Yu, Belen Alvarez-Villalonga, Soo-Kyung Kim, Yapeng Su, William A Goddard, James R Heath
Stereochemical engineering yields a multifunctional peptide macrocycle inhibitor of Akt2 by fine-tuning macrocycle-cell membrane interactions. Communications chemistry 6 (1) (2023)
Arundhati Nag, Amirhossein Mafi, Samir Das, Mary Beth Yu, Belen Alvarez-Villalonga, Soo-Kyung Kim, Yapeng Su, William A Goddard, James R Heath
Stereochemical engineering yields a multifunctional peptide macrocycle inhibitor of Akt2 by fine-tuning macrocycle-cell membrane interactions. Communications chemistry 6 (1) (2023)
Arundhati Nag, Amirhossein Mafi, Samir Das, Mary Beth Yu, Belen Alvarez-Villalonga, Soo-Kyung Kim, Yapeng Su, William A Goddard, James R Heath
Stereochemical engineering yields a multifunctional peptide macrocycle inhibitor of Akt2 by fine-tuning macrocycle-cell membrane interactions. Communications chemistry 6 (1) (2023)
Arundhati Nag, Amirhossein Mafi, Samir Das, Mary Beth Yu, Belen Alvarez-Villalonga, Soo-Kyung Kim, Yapeng Su, William A Goddard, James R Heath
Stereochemical engineering yields a multifunctional peptide macrocycle inhibitor of Akt2 by fine-tuning macrocycle-cell membrane interactions. Communications chemistry 6 (1) (2023)
Amirhossein Mafi, Soo-Kyung Kim, William A Goddard Iii
The mechanism for ligand activation of the GPCR-G protein complex. Proceedings of the National Academy of Sciences of the United States of America 119 (18) (2022)
Amirhossein Mafi, Soo-Kyung Kim, William A Goddard Iii
The G protein-first activation mechanism of opioid receptors by Gi protein and agonists. QRB discovery 2 (2021)
Amirhossein Mafi, Soo-Kyung Kim, Keng C Chou, Brian Güthrie, William A Goddard Iii
Predicted Structure of Fully Activated Tas1R3/1R3' Homodimer Bound to G Protein and Natural Sugars: Structural Insights into G Protein Activation by a Class C Sweet Taste Homodimer with Natural Sugars. Journal of the American Chemical Society 143 (40) (2021)
Amirhossein Mafi, Rahul Purohit, Erika Vielmas, Alexa R Lauinger, Brandon Lam, Yu-Shiuan Cheng, Tianyi Zhang, Yiran Huang, Soo-Kyung Kim, William A Goddard, Alison E Ondrus
Hedgehog proteins create a dynamic cholesterol interface. PloS one 16 (2) (2021)
Donghwa Kim, Alina Tokmakova, Lauren K Lujan, Hannah R Strzelinski, Nicholas Kim, Maliheh Najari Beidokhti, Marc A Giulianotti, Amirhossein Mafi, Jung-A A Woo, Steven S An, William A Goddard Iii, Stephen B Liggett
Identification and characterization of an atypical Gαs-biased β 2 AR agonist that fails to evoke airway smooth muscle cell tachyphylaxis. Proceedings of the National Academy of Sciences of the United States of America 118 (49) (2021)
Yu-Shiuan Cheng, Tianyi Zhang, Xiang Ma, Sarida Pratuangtham, Grace C Zhang, Alexander A Ondrus, Amirhossein Mafi, Brett Lomenick, Jeffrey J Jones, Alison E Ondrus
A proteome-wide map of 20(S)-hydroxycholesterol interactors in cell membranes. Nature chemical biology 17 (12) (2021)
Moon Young Yang, Amirhossein Mafi, Soo-Kyung Kim, William A Goddard Iii, Brian Guthrie
Predicted structure of fully activated human bitter taste receptor TAS2R4 complexed with G protein and agonists. QRB discovery 2 (2021)
Amirhossein Mafi, Soo-Kyung Kim, William A Goddard Iii
Mechanism of β-arrestin recruitment by the μ-opioid G protein-coupled receptor. Proceedings of the National Academy of Sciences of the United States of America 117 (28) (2020)
Amirhossein Mafi, Soo-Kyung Kim, William A Goddard Iii
The atomistic level structure for the activated human κ-opioid receptor bound to the full Gi protein and the MP1104 agonist. Proceedings of the National Academy of Sciences of the United States of America 117 (11) (2020)

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Publication Activity (10 Years)

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Amirhossein Mafi