Hongzhe Sun

Scopus Author ID ResearcherID HKU ResearcherPage Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 56

Top Venues

Chemical science

Nature communications

Nature chemistry

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry

University of Edinburgh

University of London, Birkbeck College (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Edinburgh Sep 02 1996 - Dec 21 1998

United Kingdom

GlaxoWellcome Research Fellow :: Chemistry

Nanjing University Jul 01 1990 - Oct 02 1993

China

Assistant Lecturer and Lecturer :: Coordination Chemistry Institute, State Key Laboratory of Coordination Chemistry

Education History

University of London, Birkbeck College Oct 10 1993 - Sep 09 1996

United Kingdom

PHD :: Chemistry

Wuhan Institute of Physics and Mathematics Chinese Academy of Sciences Sep 01 1987 - Jul 01 1990

China

MSC :: State Key Laboratory of Magnetic Resonance

Publications

Liwa Shi, Jing Lu, Xin Xia, Xue Liu, Hongyan Li, Xinghua Li, Jun Zhu, Xiaofeng Li, Hongzhe Sun, Xinming Yang
Clinically used drug arsenic trioxide targets XIAP and overcomes apoptosis resistance in an organoid-based preclinical cancer model. Chemical science 15 (22) (2024)
Yu Zhou, Wenyin Shen, Ying Gao, Jianzhao Peng, Qingrong Li, Xueying Wei, Shihao Liu, Fong Sang Lam, Joan Mayol-Llinàs, Guixian Zhao, Gang Li, Yizhou Li, Hongzhe Sun, Yan Cao, Xiaoyu Li
Protein-templated ligand discovery via the selection of DNA-encoded dynamic libraries. Nature chemistry 16 (4) (2024)
Jing Lu, Xue Liu, Xinghua Li, Hongyan Li, Liwa Shi, Xin Xia, Bai-Liang He, Thomas F Meyer, Xiaofeng Li, Hongzhe Sun, Xinming Yang
Copper regulates the host innate immune response against bacterial infection via activation of ALPK1 kinase. Proceedings of the National Academy of Sciences of the United States of America 121 (4) (2024)
Yu Zhou, Wenyin Shen, Ying Gao, Jianzhao Peng, Qingrong Li, Xueying Wei, Shihao Liu, Fong Sang Lam, Joan Mayol-Llinàs, Guixian Zhao, Gang Li, Yizhou Li, Hongzhe Sun, Yan Cao, Xiaoyu Li
Protein-templated ligand discovery via the selection of DNA-encoded dynamic libraries. Nature chemistry 16 (4) (2024)
Jing Lu, Xue Liu, Xinghua Li, Hongyan Li, Liwa Shi, Xin Xia, Bai-Liang He, Thomas F Meyer, Xiaofeng Li, Hongzhe Sun, Xinming Yang
Copper regulates the host innate immune response against bacterial infection via activation of ALPK1 kinase. Proceedings of the National Academy of Sciences of the United States of America 121 (4) (2024)
Yu Zhou, Wenyin Shen, Ying Gao, Jianzhao Peng, Qingrong Li, Xueying Wei, Shihao Liu, Fong Sang Lam, Joan Mayol-Llinàs, Guixian Zhao, Gang Li, Yizhou Li, Hongzhe Sun, Yan Cao, Xiaoyu Li
Protein-templated ligand discovery via the selection of DNA-encoded dynamic libraries. Nature chemistry (2024)
Xueying Wei, Chun-Lung Chan, Ying Zhou, Kaiming Tang, Jingxin Chen, Suyu Wang, Jasper Fuk-Woo Chan, Shuo-Feng Yuan, Hongyan Li, Hongzhe Sun
Mechanistic insights into bismuth(iii) inhibition of SARS-CoV-2 helicase. Chemical science 15 (26) (2024)
Jing Lu, Xue Liu, Xinghua Li, Hongyan Li, Liwa Shi, Xin Xia, Bai-Liang He, Thomas F Meyer, Xiaofeng Li, Hongzhe Sun, Xinming Yang
Copper regulates the host innate immune response against bacterial infection via activation of ALPK1 kinase. Proceedings of the National Academy of Sciences of the United States of America 121 (4) (2024)
Liwa Shi, Jing Lu, Xin Xia, Xue Liu, Hongyan Li, Xinghua Li, Jun Zhu, Xiaofeng Li, Hongzhe Sun, Xinming Yang
Clinically used drug arsenic trioxide targets XIAP and overcomes apoptosis resistance in an organoid-based preclinical cancer model. Chemical science 15 (22) (2024)
Ying Zhou, Hongyan Li, Eric Wai-Choi Tse, Hongzhe Sun
Metal-detection based techniques and their applications in metallobiology. Chemical science 15 (27) (2024)
Ying Zhou, Hongyan Li, Eric Wai-Choi Tse, Hongzhe Sun
Metal-detection based techniques and their applications in metallobiology. Chemical science 15 (27) (2024)
Jing Lu, Xue Liu, Xinghua Li, Hongyan Li, Liwa Shi, Xin Xia, Bai-Liang He, Thomas F Meyer, Xiaofeng Li, Hongzhe Sun, Xinming Yang
Copper regulates the host innate immune response against bacterial infection via activation of ALPK1 kinase. Proceedings of the National Academy of Sciences of the United States of America 121 (4) (2024)
Yushan Xia, Xueying Wei, Peng Gao, Chenyuan Wang, Anne de Jong, Jonathan Hon Kwan Chen, María José Rodríguez-Sánchez, Alba Rodríguez-Nogales, Patricia Diez-Echave, Julio Gálvez, Federico Garcia, Weihui Wu, Richard Yi-Tsun Kao, Hongyan Li, Rubén Cebrián, Oscar Paul Kuipers, Hongzhe Sun
Bismuth-based drugs sensitize Pseudomonas aeruginosa to multiple antibiotics by disrupting iron homeostasis. Nature microbiology (2024)
Xueying Wei, Chun-Lung Chan, Ying Zhou, Kaiming Tang, Jingxin Chen, Suyu Wang, Jasper Fuk-Woo Chan, Shuo-Feng Yuan, Hongyan Li, Hongzhe Sun
Mechanistic insights into bismuth(iii) inhibition of SARS-CoV-2 helicase. Chemical science 15 (26) (2024)
Qi Zhang, Minji Wang, Xuqiao Hu, Aixin Yan, Pak Leung Ho, Hongyan Li, Hongzhe Sun
Gold drugs as colistin adjuvants in the fight against MCR-1 producing bacteria. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 28 (2) (2023)
Qi Zhang, Minji Wang, Xuqiao Hu, Aixin Yan, Pak Leung Ho, Hongyan Li, Hongzhe Sun
Gold drugs as colistin adjuvants in the fight against MCR-1 producing bacteria. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 28 (2) (2023)
Qi Zhang, Minji Wang, Xuqiao Hu, Aixin Yan, Pak Leung Ho, Hongyan Li, Hongzhe Sun
Gold drugs as colistin adjuvants in the fight against MCR-1 producing bacteria. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry (2023)
Haibo Wang, Li-Gang Hu, Hongyan Li, Yau-Tsz Lai, Xueying Wei, Xiaohan Xu, Zhenkun Cao, Huiming Cao, Qianya Wan, Yuen-Yan Chang, Aimin Xu, Qunfang Zhou, Guibin Jiang, Ming-Liang He, Hongzhe Sun
Mitochondrial ATP synthase as a direct molecular target of chromium(III) to ameliorate hyperglycaemia stress. Nature communications 14 (1) (2023)
Cheng Chen, Yinsui Xu, Peter Oelschlaeger, Jürgen Brem, Lu Liu, Dongmei Wang, Hongzhe Sun, Ke-Wu Yang
A dual covalent binder for labelling and inhibiting serine and metallo-carbapenemases. Chemical communications (Cambridge, England) (2023)
Haibo Wang, Li-Gang Hu, Hongyan Li, Yau-Tsz Lai, Xueying Wei, Xiaohan Xu, Zhenkun Cao, Huiming Cao, Qianya Wan, Yuen-Yan Chang, Aimin Xu, Qunfang Zhou, Guibin Jiang, Ming-Liang He, Hongzhe Sun
Mitochondrial ATP synthase as a direct molecular target of chromium(III) to ameliorate hyperglycaemia stress. Nature communications 14 (1) (2023)
Xiaojun He, Bingjie Han, Runming Wang, Yu Guo, Richard Y T Kao, Hongyan Li, Hongzhe Sun, Wei Xia
Dual-action gallium-flavonoid compounds for combating Pseudomonas aeruginosa infection. RSC chemical biology 4 (10) (2023)
Jingxin Chen, Ying Zhou, Xueying Wei, Xiaohan Xu, Zhenzhi Qin, Chon Phin Ong, Zi-Wei Ye, Dong-Yan Jin, Bernard Boitrel, Shuo-Feng Yuan, Jasper Fuk-Woo Chan, Hongyan Li, Hongzhe Sun
Development of Pan-Anti-SARS-CoV-2 Agents through Allosteric Inhibition of nsp14/nsp10 Complex. ACS infectious diseases (2023)
Haibo Wang, Li-Gang Hu, Hongyan Li, Yau-Tsz Lai, Xueying Wei, Xiaohan Xu, Zhenkun Cao, Huiming Cao, Qianya Wan, Yuen-Yan Chang, Aimin Xu, Qunfang Zhou, Guibin Jiang, Ming-Liang He, Hongzhe Sun
Mitochondrial ATP synthase as a direct molecular target of chromium(III) to ameliorate hyperglycaemia stress. Nature communications 14 (1) (2023)
Ying Zhou, Shuofeng Yuan, Fan Xiao, Hongyan Li, Ziwei Ye, Tianfan Cheng, Cuiting Luo, Kaiming Tang, Jianpiao Cai, Jianwen Situ, Siddharth Sridhar, Wing-Ming Chu, Anthony Raymond Tam, Hin Chu, Chi-Ming Che, Lijian Jin, Ivan Fan-Ngai Hung, Liwei Lu, Jasper Fuk-Woo Chan, Hongzhe Sun
Metal-coding assisted serological multi-omics profiling deciphers the role of selenium in COVID-19 immunity. Chemical science 14 (38) (2023)
Qi Zhang, Minji Wang, Xuqiao Hu, Aixin Yan, Pak Leung Ho, Hongyan Li, Hongzhe Sun
Gold drugs as colistin adjuvants in the fight against MCR-1 producing bacteria. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 28 (2) (2023)
Chenyuan Wang, Yushan Xia, Runming Wang, Jingru Li, Chun-Lung Chan, Richard Yi-Tsun Kao, Patrick H Toy, Pak Leung Ho, Hongyan Li, Hongzhe Sun
Metallo-sideromycin as a dual functional complex for combating antimicrobial resistance. Nature communications 14 (1) (2023)
Ying Zhou, Shuo-Feng Yuan, Kelvin Kai Wang To, Xiaohan Xu, Hongyan Li, Jian-Piao Cai, Cuiting Luo, Ivan Fan-Ngai Hung, Kwok-Hung Chan, Kwok-Yung Yuen, Yu-Feng Li, Jasper Fuk-Woo Chan, Hongzhe Sun
Multiplex metal-detection based assay (MMDA) for COVID-19 diagnosis and identification of disease severity biomarkers. Chemical science 13 (11) (2022)
Hongyan Li, Hongzhe Sun
A hydroxide lock for metallo-β-lactamases. Nature chemistry 14 (1) (2022)
Hongyan Li, Shuo-Feng Yuan, Xueying Wei, Hongzhe Sun
Metal-based strategies for the fight against COVID-19. Chemical communications (Cambridge, England) 58 (54) (2022)
Ying Zhou, Eric Wai-Choi Tse, Rock Leung, Edwin Cheung, Hongyan Li, Hongzhe Sun
Multiplex Single-Cell Analysis of Cancer Cells Enables Unbiased Uncovering Subsets Associated with Cancer Relapse: Heterogeneity of Multidrug Resistance in Precursor B-ALL. ChemMedChem (2021)
Haibo Wang, Minji Wang, Xiaohan Xu, Peng Gao, Zeling Xu, Qi Zhang, Hongyan Li, Aixin Yan, Richard Yi-Tsun Kao, Hongzhe Sun
Author Correction: Multi-target mode of action of silver against Staphylococcus aureus endows it with capability to combat antibiotic resistance. Nature communications 12 (1) (2021)
Runming Wang, Jasper Fuk-Woo Chan, Suyu Wang, Hongyan Li, Jiajia Zhao, Tiffany Ka-Yan Ip, Zhong Zuo, Kwok-Yung Yuen, Shuo-Feng Yuan, Hongzhe Sun
Orally administered bismuth drug together with N -acetyl cysteine as a broad-spectrum anti-coronavirus cocktail therapy. Chemical science 13 (8) (2021)
Darren M Griffith, Hongyan Li, Melissa V Werrett, Philip C Andrews, Hongzhe Sun
Medicinal chemistry and biomedical applications of bismuth-based compounds and nanoparticles. Chemical Society reviews 50 (21) (2021)
Xuqiao Hu, Hongyan Li, Tiffany Ka-Yan Ip, Yam Fung Cheung, Mohamad Koohi-Moghadam, Haibo Wang, Xinming Yang, Daniel N Tritton, Yuchuan Wang, Yi Wang, Runming Wang, Kwan-Ming Ng, Hua Naranmandura, Eric Wai-Choi Tse, Hongzhe Sun
Arsenic trioxide targets Hsp60, triggering degradation of p53 and survivin. Chemical science 12 (32) (2021)
Haibo Wang, Minji Wang, Xiaohan Xu, Peng Gao, Zeling Xu, Qi Zhang, Hongyan Li, Aixin Yan, Richard Yi-Tsun Kao, Hongzhe Sun
Multi-target mode of action of silver against Staphylococcus aureus endows it with capability to combat antibiotic resistance. Nature communications 12 (1) (2021)
Shuofeng Yuan, Xin Yin, Xiangzhi Meng, Jasper Fuk-Woo Chan, Zi-Wei Ye, Laura Riva, Lars Pache, Chris Chun-Yiu Chan, Pok-Man Lai, Chris Chung-Sing Chan, Vincent Kwok-Man Poon, Andrew Chak-Yiu Lee, Naoko Matsunaga, Yuan Pu, Chun-Kit Yuen, Jianli Cao, Ronghui Liang, Kaiming Tang, Li Sheng, Yushen Du, Wan Xu, Chit-Ying Lau, Ko-Yung Sit, Wing Kuk Timmy Au, Runming Wang, Yu-Yuan Zhang, Yan-Dong Tang, Thomas Mandel Clausen, Jessica Pihl, Juntaek Oh, Kong-Hung Sze, Anna Jian-Xia Zhang, Hin Chu, Raven K H Kok, Dong Wang, Xue-Hui Cai, Jeffrey D Esko, Ivan Fan-Ngai Hung, Ronald Adolphus Li, Hong-Lin Chen, Hongzhe Sun, Dong-Yan Jin, Ren Sun, Sumit K Chanda, Kwok-Yung Yuen
Clofazimine broadly inhibits coronaviruses including SARS-CoV-2. Nature 593 (7859) (2021)
Mercouri G Kanatzidis, Hongzhe Sun, Stefanie Dehnen
Bismuth-The Magic Element. Inorganic chemistry 59 (6) (2020)
Shuofeng Yuan, Runming Wang, Jasper Fuk-Woo Chan, Anna Jinxia Zhang, Tianfan Cheng, Kenn Ka-Heng Chik, Zi-Wei Ye, Suyu Wang, Andrew Chak-Yiu Lee, Lijian Jin, Hongyan Li, Dong-Yan Jin, Kwok-Yung Yuen, Hongzhe Sun
Metallodrug ranitidine bismuth citrate suppresses SARS-CoV-2 replication and relieves virus-associated pneumonia in Syrian hamsters. Nature microbiology 5 (11) (2020)
Edmund Chun Ming Tse, Hongzhe Sun
A. Sigel, E. Freisinger & R. K. O. Sigel (Eds.), M. E. Sosa Torres & P. M. H. Kroneck (volume Eds.): Transition Metals and Sulfur - A Strong Relationship for Life. Zeitschrift fur Naturforschung. C, Journal of biosciences 76 (5-6) (2020)
Hongzhe Sun, Qi Zhang, Runming Wang, Haibo Wang, Yuen-Ting Wong, Minji Wang, Quan Hao, Aixin Yan, Richard Yi-Tsun Kao, Pak Leung Ho, Hongyan Li
Resensitizing carbapenem- and colistin-resistant bacteria to antibiotics using auranofin. Nature communications 11 (1) (2020)
Tianfan Cheng, Yau-Tsz Lai, Chuan Wang, Yi Wang, Nan Jiang, Hongyan Li, Hongzhe Sun, Lijian Jin
Bismuth drugs tackle Porphyromonas gingivalis and attune cytokine response in human cells. Metallomics : integrated biometal science 11 (7) (2020)
Haibo Wang, Xinming Yang, Minji Wang, Menglong Hu, Xiaohan Xu, Aixin Yan, Quan Hao, Hongyan Li, Hongzhe Sun
Atomic differentiation of silver binding preference in protein targets: Escherichia coli malate dehydrogenase as a paradigm. Chemical science 11 (43) (2020)
Ya Yang, Nan Jiang, Yau-Tsz Lai, Yuen-Yan Chang, Xinming Yang, Hongzhe Sun, Hongyan Li
Green Fluorescent Probe for Imaging His6-Tagged Proteins Inside Living Cells. ACS sensors 4 (5) (2019)
Haibo Wang, Aixin Yan, Zhigang Liu, Xinming Yang, Zeling Xu, Yuchuan Wang, Runming Wang, Mohamad Koohi-Moghadam, Ligang Hu, Wei Xia, Huiru Tang, Yulan Wang, Hongyan Li, Hongzhe Sun
Deciphering molecular mechanism of silver by integrated omic approaches enables enhancing its antimicrobial efficacy in E. coli. PLoS biology 17 (6) (2019)
Xiaohan Xu, Haibo Wang, Hongyan Li, Xuqiao Hu, Yu Zhang, Xin-Yuan Guan, Patrick H Toy, Hongzhe Sun
S-Dimethylarsino-glutathione (darinaparsin®) targets histone H3.3, leading to TRAIL-induced apoptosis in leukemia cells. Chemical communications (Cambridge, England) 55 (87) (2019)
Yuchuan Wang, Bingjie Han, Yanxuan Xie, Haibo Wang, Runming Wang, Wei Xia, Hongyan Li, Hongzhe Sun
Combination of gallium(iii) with acetate for combating antibiotic resistant Pseudomonas aeruginosa. Chemical science 10 (24) (2019)
Yuchuan Wang, Hongyan Li, Hongzhe Sun
Metalloproteomics for Unveiling the Mechanism of Action of Metallodrugs. Inorganic chemistry 58 (20) (2019)
Haibo Wang, Minji Wang, Xinming Yang, Xiaohan Xu, Quan Hao, Aixin Yan, Menglong Hu, Ryszard Lobinski, Hongyan Li, Hongzhe Sun
Antimicrobial silver targets glyceraldehyde-3-phosphate dehydrogenase in glycolysis of E. coli. Chemical science 10 (30) (2019)
Runming Wang, Tsz-Pui Lai, Peng Gao, Hongmin Zhang, Pak-Leung Ho, Patrick Chiu-Yat Woo, Guixing Ma, Richard Yi-Tsun Kao, Hongyan Li, Hongzhe Sun
Bismuth antimicrobial drugs serve as broad-spectrum metallo-β-lactamase inhibitors. Nature communications 9 (1) (2018)
Ying Zhou, Hongyan Li, Hongzhe Sun
Cytotoxicity of arsenic trioxide in single leukemia cells by time-resolved ICP-MS together with lanthanide tags. Chemical communications (Cambridge, England) 53 (20) (2018)
Hongyan Li, Runming Wang, Hongzhe Sun
Systems Approaches for Unveiling the Mechanism of Action of Bismuth Drugs: New Medicinal Applications beyond Helicobacter Pylori Infection. Accounts of chemical research 52 (1) (2018)
Bingjie Han, Zhen Zhang, Yanxuan Xie, Xuqiao Hu, Haibo Wang, Wei Xia, Yulan Wang, Hongyan Li, Yuchuan Wang, Hongzhe Sun
Multi-omics and temporal dynamics profiling reveal disruption of central metabolism in Helicobacter pylori on bismuth treatment. Chemical science 9 (38) (2018)
Ying Zhou, Haibo Wang, Eric Tse, Hongyan Li, Hongzhe Sun
Cell Cycle-Dependent Uptake and Cytotoxicity of Arsenic-Based Drugs in Single Leukemia Cells. Analytical chemistry 90 (17) (2018)
Yau-Tsz Lai, Ya Yang, Ligang Hu, Tianfan Cheng, Yuen-Yan Chang, Mohamad Koohi-Moghadam, Yuchuan Wang, Jiang Xia, Junwen Wang, Hongyan Li, Hongzhe Sun
Integration of fluorescence imaging with proteomics enables visualization and identification of metallo-proteomes in living cells. Metallomics : integrated biometal science 9 (1) (2017)
Xiangwen Liao, Fang Yang, Runming Wang, Xiaojun He, Hongyan Li, Richard Y T Kao, Wei Xia, Hongzhe Sun
Identification of catabolite control protein A from Staphylococcus aureus as a target of silver ions. Chemical science 8 (12) (2017)
Yuchuan Wang, Li-Gang Hu, Feng Xu, Quan Quan, Yau-Tsz Lai, Wei Xia, Ya Yang, Yuen-Yan Chang, Xinming Yang, Zhifang Chai, Junwen Wang, Ivan K Chu, Hongyan Li, Hongzhe Sun
Integrative approach for the analysis of the proteome-wide response to bismuth drugs in Helicobacter pylori. Chemical science 8 (6) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Hongzhe Sun