Ian A Taylor (Ian Taylor)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 44

Top Venues

Blood

Nature communications

Nature

The EMBO journal

Francis Crick Institute

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Francis Crick Institute Apr 01 2015

United Kingdom

Head :: Macrmolecular Structure Laboratory

Publications

Mohammad Hamdy Abdelrazak Morsy, Ingrid Lilienthal, Martin Lord, Magali Merrien, Agata Magdalena Wasik, Virginia Amador, Marta Sureda-Gómez, Henrik J Johansson, Janne Lehtiö, Beatriz Garcia-Torre, José Ignacio Martin-Subero, Nikolaos Tsesmetzis, Sijia Tao, Raymond F Schinazi, Baek Kim, Agnes L Sorteberg, Malin Wickström, Devon Sheppard, Georgios Z Rassidakis, Ian A Taylor, Birger Christensson, Elias Campo, Nikolas Herold, Birgitta Sander
SOX11 is a novel binding partner and endogenous inhibitor of SAMHD1 ara-CTPase activity in mantle cell lymphoma. Blood (2024)
Mohammad Hamdy Abdelrazak Morsy, Ingrid Lilienthal, Martin Lord, Magali Merrien, Agata Magdalena Wasik, Marta Sureda-Gómez, Virginia Amador, Henrik J Johansson, Janne Lehtiö, Beatriz Garcia-Torre, José Ignacio Martin-Subero, Nikolaos Tsesmetzis, Sijia Tao, Raymond F Schinazi, Baek Kim, Agnes L Sorteberg, Malin Wickström, Devon Sheppard, Georgios Z Rassidakis, Ian A Taylor, Birger Christensson, Elias Campo, Nikolas Herold, Birgitta Sander
SOX11 is a novel binding partner and endogenous inhibitor of SAMHD1 ara-CTPase activity in mantle cell lymphoma. Blood 143 (19) (2024)
Chih-Chao Liang, Luke A Greenhough, Laura Masino, Sarah Maslen, Ilirjana Bajrami, Marcel Tuppi, J Mark Skehel, Ian A Taylor, Stephen C West
Mechanism of single-stranded DNA annealing by RAD52-RPA complex. Nature 629 (8012) (2024)
Mohammad Hamdy Abdelrazak Morsy, Ingrid Lilienthal, Martin Lord, Magali Merrien, Agata Magdalena Wasik, Marta Sureda-Gómez, Virginia Amador, Henrik J Johansson, Janne Lehtiö, Beatriz Garcia-Torre, José Ignacio Martin-Subero, Nikolaos Tsesmetzis, Sijia Tao, Raymond F Schinazi, Baek Kim, Agnes L Sorteberg, Malin Wickström, Devon Sheppard, Georgios Z Rassidakis, Ian A Taylor, Birger Christensson, Elias Campo, Nikolas Herold, Birgitta Sander
SOX11 is a novel binding partner and endogenous inhibitor of SAMHD1 ara-CTPase activity in mantle cell lymphoma. Blood 143 (19) (2024)
Mohammad Hamdy Abdelrazak Morsy, Ingrid Lilienthal, Martin Lord, Magali Merrien, Agata Magdalena Wasik, Marta Sureda-Gómez, Virginia Amador, Henrik J Johansson, Janne Lehtiö, Beatriz Garcia-Torre, José Ignacio Martin-Subero, Nikolaos Tsesmetzis, Sijia Tao, Raymond F Schinazi, Baek Kim, Agnes L Sorteberg, Malin Wickström, Devon Sheppard, Georgios Z Rassidakis, Ian A Taylor, Birger Christensson, Elias Campo, Nikolas Herold, Birgitta Sander
SOX11 is a novel binding partner and endogenous inhibitor of SAMHD1 ara-CTPase activity in mantle cell lymphoma. Blood 143 (19) (2024)
Chih-Chao Liang, Luke A Greenhough, Laura Masino, Sarah Maslen, Ilirjana Bajrami, Marcel Tuppi, J Mark Skehel, Ian A Taylor, Stephen C West
Mechanism of single-stranded DNA annealing by RAD52-RPA complex. Nature (2024)
Mohammad Hamdy Abdelrazak Morsy, Ingrid Lilienthal, Martin Lord, Magali Merrien, Agata Magdalena Wasik, Virginia Amador, Marta Sureda-Gómez, Henrik J Johansson, Janne Lehtiö, Beatriz Garcia-Torre, José Ignacio Martin-Subero, Nikolaos Tsesmetzis, Sijia Tao, Raymond F Schinazi, Baek Kim, Agnes L Sorteberg, Malin Wickström, Devon Sheppard, Georgios Z Rassidakis, Ian A Taylor, Birger Christensson, Elias Campo, Nikolas Herold, Birgitta Sander
SOX11 is a novel binding partner and endogenous inhibitor of SAMHD1 ara-CTPase activity in mantle cell lymphoma. Blood (2024)
Oliver J Acton, Devon Sheppard, Simone Kunzelmann, Sarah J Caswell, Andrea Nans, Ailidh J O Burgess, Geoff Kelly, Elizabeth R Morris, Peter B Rosenthal, Ian A Taylor
Platform-directed allostery and quaternary structure dynamics of SAMHD1 catalysis. Nature communications 15 (1) (2024)
Mohammad Hamdy Abdelrazak Morsy, Ingrid Lilienthal, Martin Lord, Magali Merrien, Agata Magdalena Wasik, Marta Sureda-Gómez, Virginia Amador, Henrik J Johansson, Janne Lehtiö, Beatriz Garcia-Torre, José Ignacio Martin-Subero, Nikolaos Tsesmetzis, Sijia Tao, Raymond F Schinazi, Baek Kim, Agnes L Sorteberg, Malin Wickström, Devon Sheppard, Georgios Z Rassidakis, Ian A Taylor, Birger Christensson, Elias Campo, Nikolas Herold, Birgitta Sander
SOX11 is a novel binding partner and endogenous inhibitor of SAMHD1 ara-CTPase activity in mantle cell lymphoma. Blood 143 (19) (2024)
Oliver J Acton, Devon Sheppard, Simone Kunzelmann, Sarah J Caswell, Andrea Nans, Ailidh J O Burgess, Geoff Kelly, Elizabeth R Morris, Peter B Rosenthal, Ian A Taylor
Platform-directed allostery and quaternary structure dynamics of SAMHD1 catalysis. Nature communications 15 (1) (2024)
Mohammad Hamdy Abdelrazak Morsy, Ingrid Lilienthal, Martin Lord, Magali Merrien, Agata Magdalena Wasik, Virginia Amador, Marta Sureda-Gómez, Henrik J Johansson, Janne Lehtiö, Beatriz Garcia-Torre, José Ignacio Martin-Subero, Nikolaos Tsesmetzis, Sijia Tao, Raymond F Schinazi, Baek Kim, Agnes L Sorteberg, Malin Wickström, Devon Sheppard, Georgios Z Rassidakis, Ian A Taylor, Birger Christensson, Elias Campo, Nikolas Herold, Birgitta Sander
SOX11 is a novel binding partner and endogenous inhibitor of SAMHD1 ara-CTPase activity in mantle cell lymphoma. Blood (2024)
Tom Bland, Nisha Hirani, David C Briggs, Riccardo Rossetto, KangBo Ng, Ian A Taylor, Neil Q McDonald, David Zwicker, Nathan W Goehring
Optimized PAR-2 RING dimerization mediates cooperative and selective membrane binding for robust cell polarity. The EMBO journal 43 (15) (2024)
Chih-Chao Liang, Luke A Greenhough, Laura Masino, Sarah Maslen, Ilirjana Bajrami, Marcel Tuppi, J Mark Skehel, Ian A Taylor, Stephen C West
Mechanism of single-stranded DNA annealing by RAD52-RPA complex. Nature 629 (8012) (2024)
Oliver J Acton, Devon Sheppard, Simone Kunzelmann, Sarah J Caswell, Andrea Nans, Ailidh J O Burgess, Geoff Kelly, Elizabeth R Morris, Peter B Rosenthal, Ian A Taylor
Platform-directed allostery and quaternary structure dynamics of SAMHD1 catalysis. Nature communications 15 (1) (2024)
Tom Bland, Nisha Hirani, David C Briggs, Riccardo Rossetto, KangBo Ng, Ian A Taylor, Neil Q McDonald, David Zwicker, Nathan W Goehring
Optimized PAR-2 RING dimerization mediates cooperative and selective membrane binding for robust cell polarity. The EMBO journal (2024)
Oliver J Acton, Devon Sheppard, Simone Kunzelmann, Sarah J Caswell, Andrea Nans, Ailidh J O Burgess, Geoff Kelly, Elizabeth R Morris, Peter B Rosenthal, Ian A Taylor
Platform-directed allostery and quaternary structure dynamics of SAMHD1 catalysis. Nature communications 15 (1) (2024)
Chih-Chao Liang, Luke A Greenhough, Laura Masino, Sarah Maslen, Ilirjana Bajrami, Marcel Tuppi, J Mark Skehel, Ian A Taylor, Stephen C West
Mechanism of single-stranded DNA annealing by RAD52-RPA complex. Nature 629 (8012) (2024)
Chih-Chao Liang, Luke A Greenhough, Laura Masino, Sarah Maslen, Ilirjana Bajrami, Marcel Tuppi, J Mark Skehel, Ian A Taylor, Stephen C West
Mechanism of single-stranded DNA annealing by RAD52-RPA complex. Nature 629 (8012) (2024)
Chih-Chao Liang, Luke A Greenhough, Laura Masino, Sarah Maslen, Ilirjana Bajrami, Marcel Tuppi, J Mark Skehel, Ian A Taylor, Stephen C West
Mechanism of single-stranded DNA annealing by RAD52-RPA complex. Nature (2024)
Mohammad Hamdy Abdelrazak Morsy, Ingrid Lilienthal, Martin Lord, Magali Merrien, Agata Magdalena Wasik, Marta Sureda-Gómez, Virginia Amador, Henrik J Johansson, Janne Lehtiö, Beatriz Garcia-Torre, José Ignacio Martin-Subero, Nikolaos Tsesmetzis, Sijia Tao, Raymond F Schinazi, Baek Kim, Agnes L Sorteberg, Malin Wickström, Devon Sheppard, Georgios Z Rassidakis, Ian A Taylor, Birger Christensson, Elias Campo, Nikolas Herold, Birgitta Sander
SOX11 is a novel binding partner and endogenous inhibitor of SAMHD1 ara-CTPase activity in mantle cell lymphoma. Blood 143 (19) (2024)
Mohammad Hamdy Abdelrazak Morsy, Ingrid Lilienthal, Martin Lord, Magali Merrien, Agata Magdalena Wasik, Marta Sureda-Gómez, Virginia Amador, Henrik J Johansson, Janne Lehtiö, Beatriz Garcia-Torre, José Ignacio Martin-Subero, Nikolaos Tsesmetzis, Sijia Tao, Raymond F Schinazi, Baek Kim, Agnes L Sorteberg, Malin Wickström, Devon Sheppard, Georgios Z Rassidakis, Ian A Taylor, Birger Christensson, Elias Campo, Nikolas Herold, Birgitta Sander
SOX11 is a novel binding partner and endogenous inhibitor of SAMHD1 ara-CTPase activity in mantle cell lymphoma. Blood 143 (19) (2024)
Tom Bland, Nisha Hirani, David C Briggs, Riccardo Rossetto, KangBo Ng, Ian A Taylor, Neil Q McDonald, David Zwicker, Nathan W Goehring
Optimized PAR-2 RING dimerization mediates cooperative and selective membrane binding for robust cell polarity. The EMBO journal 43 (15) (2024)
Tom Bland, Nisha Hirani, David C Briggs, Riccardo Rossetto, KangBo Ng, Ian A Taylor, Neil Q McDonald, David Zwicker, Nathan W Goehring
Optimized PAR-2 RING dimerization mediates cooperative and selective membrane binding for robust cell polarity. The EMBO journal 43 (15) (2024)
Chih-Chao Liang, Luke A Greenhough, Laura Masino, Sarah Maslen, Ilirjana Bajrami, Marcel Tuppi, J Mark Skehel, Ian A Taylor, Stephen C West
Mechanism of single-stranded DNA annealing by RAD52-RPA complex. Nature 629 (8012) (2024)
Mohammad Hamdy Abdelrazak Morsy, Ingrid Lilienthal, Martin Lord, Magali Merrien, Agata Magdalena Wasik, Virginia Amador, Marta Sureda-Gómez, Henrik J Johansson, Janne Lehtiö, Beatriz Garcia-Torre, José Ignacio Martin-Subero, Nikolaos Tsesmetzis, Sijia Tao, Raymond F Schinazi, Baek Kim, Agnes L Sorteberg, Malin Wickström, Devon Sheppard, Georgios Z Rassidakis, Ian A Taylor, Birger Christensson, Elias Campo, Nikolas Herold, Birgitta Sander
SOX11 is a novel binding partner and endogenous inhibitor of SAMHD1 ara-CTPase activity in mantle cell lymphoma. Blood (2024)
Mohammad Hamdy Abdelrazak Morsy, Ingrid Lilienthal, Martin Lord, Magali Merrien, Agata Magdalena Wasik, Marta Sureda-Gómez, Virginia Amador, Henrik J Johansson, Janne Lehtiö, Beatriz Garcia-Torre, José Ignacio Martin-Subero, Nikolaos Tsesmetzis, Sijia Tao, Raymond F Schinazi, Baek Kim, Agnes L Sorteberg, Malin Wickström, Devon Sheppard, Georgios Z Rassidakis, Ian A Taylor, Birger Christensson, Elias Campo, Nikolas Herold, Birgitta Sander
SOX11 is a novel binding partner and endogenous inhibitor of SAMHD1 ara-CTPase activity in mantle cell lymphoma. Blood 143 (19) (2024)
Ian A Taylor, Ariberto Fassati
The capsid revolution. Journal of molecular cell biology (2023)
Giuseppe Nicastro, Giancarlo Abis, Pierre Klein, Sofia Esteban Serna, Christopher Gallagher, Belen Chaves-Arquero, Yuyang Cai, Angelo Miguel Figueiredo, Stephen R Martin, Rickie Patani, Ian A Taylor, Andres Ramos
Direct m6A recognition by IMP1 underlays an alternative model of target selection for non-canonical methyl-readers. Nucleic acids research (2023)
Neil J Rzechorzek, Simone Kunzelmann, Andrew G Purkiss, Mariana Silva Dos Santos, James I MacRae, Ian A Taylor, Kasper Fugger, Stephen C West
Mechanism of substrate hydrolysis by the human nucleotide pool sanitiser DNPH1. Nature communications 14 (1) (2023)
Allison Ballandras-Colas, Vidya Chivukula, Dominika T Gruszka, Zelin Shan, Parmit Kumar Singh, Valerie E Pye, Rebecca K McLean, Gregory J Bedwell, Wen Li, Andrea Nans, Nicola J Cook, Hind J Fadel, Eric M Poeschla, David J Griffiths, Javier Vargas, Ian A Taylor, Dmitry Lyumkis, Hasan Yardimci, Alan N Engelman, Peter Cherepanov
Multivalent interactions essential for lentiviral integrase function. Nature communications 13 (1) (2022)
Matthew A Cottee, Sean L Beckwith, Suzanne C Letham, Sarah J Kim, George R Young, Jonathan P Stoye, David J Garfinkel, Ian A Taylor
Structure of a Ty1 restriction factor reveals the molecular basis of transposition copy number control. Nature communications 12 (1) (2021)
Anabel Guedán, Callum D Donaldson, Eve R Caroe, Ophélie Cosnefroy, Ian A Taylor, Kate N Bishop
HIV-1 requires capsid remodelling at the nuclear pore for nuclear entry and integration. PLoS pathogens 17 (9) (2021)
Elizabeth R Morris, Simone Kunzelmann, Sarah J Caswell, Andrew G Purkiss, Geoff Kelly, Ian A Taylor
Probing the Catalytic Mechanism and Inhibition of SAMHD1 Using the Differential Properties of Rp- and Sp-dNTPαS Diastereomers. Biochemistry 60 (21) (2021)
Kasper Fugger, Ilirjana Bajrami, Mariana Silva Dos Santos, Sarah Jane Young, Simone Kunzelmann, Geoff Kelly, Graeme Hewitt, Harshil Patel, Robert Goldstone, Thomas Carell, Simon J Boulton, James I MacRae, Ian A Taylor, Stephen C West
Targeting the nucleotide salvage factor DNPH1 sensitizes BRCA-deficient cells to PARP inhibitors. Science (New York, N.Y.) 372 (6538) (2021)
Zuzana Hodáková, Andrea Nans, Simone Kunzelmann, Shahid Mehmood, Ian A Taylor, Frank Uhlmann, Peter Cherepanov, Martin R Singleton
Structural characterisation of the Chaetomium thermophilum Chl1 helicase. PloS one 16 (5) (2021)
Sofia Banchenko, Ferdinand Krupp, Christine Gotthold, Jörg Bürger, Andrea Graziadei, Francis J O'Reilly, Ludwig R Sinn, Olga Ruda, Juri Rappsilber, Christian M T Spahn, Thorsten Mielke, Ian A Taylor, David Schwefel
Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses. PLoS pathogens 17 (8) (2021)
Elizabeth R Morris, Sarah J Caswell, Simone Kunzelmann, Laurence H Arnold, Andrew G Purkiss, Geoff Kelly, Ian A Taylor
Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis. Nature communications 11 (1) (2020)
Matthew A Cottee, Suzanne C Letham, George R Young, Jonathan P Stoye, Ian A Taylor
Structure of Drosophila melanogaster ARC1 reveals a repurposed molecule with characteristics of retroviral Gag. Science advances 6 (1) (2020)
Johanna Roostalu, Claire Thomas, Nicholas Ian Cade, Simone Kunzelmann, Ian A Taylor, Thomas Surrey
The speed of GTP hydrolysis determines GTP cap size and controls microtubule stability. eLife 9 (2020)
Christopher Monit, Elizabeth R Morris, Christopher Ruis, Bart Szafran, Grant Thiltgen, Ming-Han Chloe Tsai, N Avrion Mitchison, Kate N Bishop, Jonathan P Stoye, Ian A Taylor, Ariberto Fassati, Richard A Goldstein
Positive selection in dNTPase SAMHD1 throughout mammalian evolution. Proceedings of the National Academy of Sciences of the United States of America 116 (37) (2019)
Oliver J Acton, Timothy Grant, Giuseppe Nicastro, Neil J Ball, David C Goldstone, Laura E Robertson, Kasim Sader, Andrea Nans, Andres Ramos, Jonathan P Stoye, Ian A Taylor, Peter B Rosenthal
Structural basis for Fullerene geometry in a human endogenous retrovirus capsid. Nature communications 10 (1) (2019)
Guorui Li, Jinguang Huang, Jun Yang, Dan He, Chao Wang, Xiaoxuan Qi, Ian A Taylor, Junfeng Liu, You-Liang Peng
Structure based function-annotation of hypothetical protein MGG_01005 from Magnaporthe oryzae reveals it is the dynein light chain orthologue of dynlt1/3. Scientific reports 8 (1) (2018)
Fruzsina Hobor, Andre Dallmann, Neil J Ball, Carla Cicchini, Cecilia Battistelli, Roksana W Ogrodowicz, Evangelos Christodoulou, Stephen R Martin, Alfredo Castello, Marco Tripodi, Ian A Taylor, Andres Ramos
A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets. Nature communications 9 (1) (2018)
Neil J Ball, Giuseppe Nicastro, Moumita Dutta, Dominic J Pollard, David C Goldstone, Marta Sanz-Ramos, Andres Ramos, Erik Müllers, Kristin Stirnnagel, Nicole Stanke, Dirk Lindemann, Jonathan P Stoye, William R Taylor, Peter B Rosenthal, Ian A Taylor
Structure of a Spumaretrovirus Gag Central Domain Reveals an Ancient Retroviral Capsid. PLoS pathogens 12 (11) (2016)

Ian A Taylor.css-eqlu8i{font-size:small;padding-left:4px;} (Ian Taylor)

Publication Activity (10 Years)

Top Topics

Top Venues

Ian A Taylor (Ian Taylor)