Rickie Patani

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 37

Top Venues

Nature communications

Brain : a journal of neurology

International journal of molecular sciences

Genome research

UCL Institute of Neurology, University College London

University of Cambridge (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

UCL Institute of Neurology, University College London Oct 01 2013

United Kingdom

Wellcome Trust Clinician Scientist :: Department of Molecular Neuroscience

Addenbrooke's Hospital Jun 01 2013

United Kingdom

Senior Specialist Registrar in Neurology :: Neurology

Addenbrooke's Hospital Jul 01 2007 - Oct 01 2013

United Kingdom

Specialist Registrar in Neurology :: Neurology

University of Cambridge Feb 01 2008 - Feb 01 2011

United Kingdom

Wellcome Trust Clinical Research Training Fellow / PhD Clinician :: Human Pluripotent Stem Cell Biology

Hammersmith Hospital Feb 01 2006 - Jul 01 2007

United Kingdom

Senior House Officer :: Acute Medicine / Cardiology / Renal / Endocrinology

National Hospital for Neurology and Neurosurgery Aug 01 2005 - Feb 01 2006

United Kingdom

Senior House Officer :: Neurology

Education History

University of Cambridge Jul 01 2007 - Feb 01 2011

United Kingdom

PHD :: Human Pluripotent Stem Cell Biology

Imperial College Faculty of Medicine Oct 02 1998 - Aug 01 2004

United Kingdom

BSC :: Medicine

Imperial College London Jul 01 2001 - Jul 02 2002

United Kingdom

BSC :: Neuroscience

Publications

Christy Hung, Emre Fertan, Frederick J Livesey, David Klenerman, Rickie Patani
APP antisense oligonucleotides reduce amyloid-β aggregation and rescue endolysosomal dysfunction in Alzheimer's disease. Brain : a journal of neurology 147 (7) (2024)
Christy Hung, Emre Fertan, Frederick J Livesey, David Klenerman, Rickie Patani
APP antisense oligonucleotides reduce Aβ aggregation and rescue endolysosomal dysfunction in Alzheimer's disease. Brain : a journal of neurology (2024)
Christy Hung, Emre Fertan, Frederick J Livesey, David Klenerman, Rickie Patani
APP antisense oligonucleotides reduce amyloid-β aggregation and rescue endolysosomal dysfunction in Alzheimer's disease. Brain : a journal of neurology 147 (7) (2024)
Christy Hung, Emre Fertan, Frederick J Livesey, David Klenerman, Rickie Patani
APP antisense oligonucleotides reduce amyloid-β aggregation and rescue endolysosomal dysfunction in Alzheimer's disease. Brain : a journal of neurology 147 (7) (2024)
Pierre Klein, Marija Petrić Howe, Jasmine Harley, Harry Crook, Sofia Esteban Serna, Theodoros I Roumeliotis, Jyoti Sharma Choudhary, Anob M Chakrabarti, Raphaëlle Luisier, Rickie Patani, Andres Ramos
m6a methylation orchestrates IMP1 regulation of microtubules during human neuronal differentiation. Nature communications 15 (1) (2024)
Pierre Klein, Marija Petrić Howe, Jasmine Harley, Harry Crook, Sofia Esteban Serna, Theodoros I Roumeliotis, Jyoti Sharma Choudhary, Anob M Chakrabarti, Raphaëlle Luisier, Rickie Patani, Andres Ramos
m6a methylation orchestrates IMP1 regulation of microtubules during human neuronal differentiation. Nature communications 15 (1) (2024)
Pierre Klein, Marija Petrić Howe, Jasmine Harley, Harry Crook, Sofia Esteban Serna, Theodoros I Roumeliotis, Jyoti Sharma Choudhary, Anob M Chakrabarti, Raphaëlle Luisier, Rickie Patani, Andres Ramos
m6a methylation orchestrates IMP1 regulation of microtubules during human neuronal differentiation. Nature communications 15 (1) (2024)
Pierre Klein, Marija Petrić Howe, Jasmine Harley, Harry Crook, Sofia Esteban Serna, Theodoros I Roumeliotis, Jyoti Sharma Choudhary, Anob M Chakrabarti, Raphaëlle Luisier, Rickie Patani, Andres Ramos
m6a methylation orchestrates IMP1 regulation of microtubules during human neuronal differentiation. Nature communications 15 (1) (2024)
Pierre Klein, Marija Petrić Howe, Jasmine Harley, Harry Crook, Sofia Esteban Serna, Theodoros I Roumeliotis, Jyoti Sharma Choudhary, Anob M Chakrabarti, Raphaëlle Luisier, Rickie Patani, Andres Ramos
m6a methylation orchestrates IMP1 regulation of microtubules during human neuronal differentiation. Nature communications 15 (1) (2024)
Oliver Jonathan Ziff, Jacob Neeves, Jamie Mitchell, Giulia E Tyzack, Carlos Martínez-Ruiz, Raphaelle Luisier, Anob M Chakrabarti, Nicholas McGranahan, Kevin Litchfield, Simon J Boulton, Ammar Al Chalabi, Gavin P Kelly, Jack Humphrey, Rickie Patani
Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology. Nature communications 14 (1) (2023)
Oliver Jonathan Ziff, Jacob Neeves, Jamie Mitchell, Giulia E Tyzack, Carlos Martínez-Ruiz, Raphaelle Luisier, Anob M Chakrabarti, Nicholas McGranahan, Kevin Litchfield, Simon J Boulton, Ammar Al Chalabi, Gavin P Kelly, Jack Humphrey, Rickie Patani
Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology. Nature communications 14 (1) (2023)
Giuseppe Nicastro, Giancarlo Abis, Pierre Klein, Sofia Esteban Serna, Christopher Gallagher, Belen Chaves-Arquero, Yuyang Cai, Angelo Miguel Figueiredo, Stephen R Martin, Rickie Patani, Ian A Taylor, Andres Ramos
Direct m6A recognition by IMP1 underlays an alternative model of target selection for non-canonical methyl-readers. Nucleic acids research (2023)
Federica Raguseo, Yiran Wang, Jessica Li, Marija Petrić Howe, Rubika Balendra, Anouk Huyghebaert, Devkee M Vadukul, Diana A Tanase, Thomas E Maher, Layla Malouf, Roger Rubio-Sánchez, Francesco Antonio Aprile, Yuval Elani, Rickie Patani, Lorenzo Di Michele, Marco Di Antonio
The ALS/FTD-related C9orf72 hexanucleotide repeat expansion forms RNA condensates through multimolecular G-quadruplexes. Nature communications 14 (1) (2023)
Oliver Jonathan Ziff, Jacob Neeves, Jamie Mitchell, Giulia E Tyzack, Carlos Martínez-Ruiz, Raphaelle Luisier, Anob M Chakrabarti, Nicholas McGranahan, Kevin Litchfield, Simon J Boulton, Ammar Al Chalabi, Gavin P Kelly, Jack Humphrey, Rickie Patani
Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology. Nature communications 14 (1) (2023)
Oliver Jonathan Ziff, Jacob Neeves, Jamie Mitchell, Giulia E Tyzack, Carlos Martínez-Ruiz, Raphaelle Luisier, Anob M Chakrabarti, Nicholas McGranahan, Kevin Litchfield, Simon J Boulton, Ammar Al Chalabi, Gavin P Kelly, Jack Humphrey, Rickie Patani
Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology. Nature communications 14 (1) (2023)
Christy Hung, Rickie Patani
Elevated 4R tau contributes to endolysosomal dysfunction and neurodegeneration in VCP-related frontotemporal dementia. Brain : a journal of neurology (2023)
Rickie Patani, Giles E Hardingham, Shane A Liddelow
Functional roles of reactive astrocytes in neuroinflammation and neurodegeneration. Nature reviews. Neurology (2023)
Oliver Jonathan Ziff, Jacob Neeves, Jamie Mitchell, Giulia E Tyzack, Carlos Martínez-Ruiz, Raphaelle Luisier, Anob M Chakrabarti, Nicholas McGranahan, Kevin Litchfield, Simon J Boulton, Ammar Al Chalabi, Gavin P Kelly, Jack Humphrey, Rickie Patani
Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology. Nature communications 14 (1) (2023)
Oliver Jonathan Ziff, Jacob Neeves, Jamie Mitchell, Giulia E Tyzack, Carlos Martínez-Ruiz, Raphaelle Luisier, Anob M Chakrabarti, Nicholas McGranahan, Kevin Litchfield, Simon J Boulton, Ammar Al Chalabi, Gavin P Kelly, Jack Humphrey, Rickie Patani
Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology. Nature communications 14 (1) (2023)
Oliver Jonathan Ziff, Jacob Neeves, Jamie Mitchell, Giulia E Tyzack, Carlos Martínez-Ruiz, Raphaelle Luisier, Anob M Chakrabarti, Nicholas McGranahan, Kevin Litchfield, Simon J Boulton, Ammar Al Chalabi, Gavin P Kelly, Jack Humphrey, Rickie Patani
Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology. Nature communications 14 (1) (2023)
Phillip Smethurst, Hannah Franklin, Benjamin E Clarke, Katie Sidle, Rickie Patani
The role of astrocytes in prion-like mechanisms of neurodegeneration. Brain : a journal of neurology 145 (1) (2022)
Doaa M Taha, Benjamin E Clarke, Claire E Hall, Giulia E Tyzack, Oliver J Ziff, Linda Greensmith, Bernadett Kalmar, Mhoriam Ahmed, Aftab Alam, Eric Peter Thelin, Nuria Marco Garcia, Adel Helmy, Christopher R Sibley, Rickie Patani
Astrocytes display cell autonomous and diverse early reactive states in familial amyotrophic lateral sclerosis. Brain : a journal of neurology 145 (2) (2022)
Marija Petrić Howe, Hamish Crerar, Jacob Neeves, Jasmine Harley, Giulia E Tyzack, Pierre Klein, Andres Ramos, Rickie Patani, Raphaëlle Luisier
Physiological intron retaining transcripts in the cytoplasm abound during human motor neurogenesis. Genome research 32 (10) (2022)
Virenkumar A Pandya, Hamish Crerar, Jamie S Mitchell, Rickie Patani
A Non-Toxic Concentration of Telomerase Inhibitor BIBR1532 Fails to Reduce TERT Expression in a Feeder-Free Induced Pluripotent Stem Cell Model of Human Motor Neurogenesis. International journal of molecular sciences 22 (6) (2021)
Giulia E Tyzack, Jacob Neeves, Hamish Crerar, Pierre Klein, Oliver Ziff, Doaa M Taha, Raphaëlle Luisier, Nicholas M Luscombe, Rickie Patani
Aberrant cytoplasmic intron retention is a blueprint for RNA binding protein mislocalization in VCP-related amyotrophic lateral sclerosis. Brain : a journal of neurology 144 (7) (2021)
Roberto Simone, Faiza Javad, Warren Emmett, Oscar G Wilkins, Filipa Lourenço Almeida, Natalia Barahona-Torres, Justyna Zareba-Paslawska, Mazdak Ehteramyan, Paola Zuccotti, Angelika Modelska, Kavitha Siva, Gurvir S Virdi, Jamie S Mitchell, Jasmine Harley, Victoria A Kay, Geshanthi Hondhamuni, Daniah Trabzuni, Mina Ryten, Selina Wray, Elisavet Preza, Demis A Kia, Alan M Pittman, Raffaele Ferrari, Claudia Manzoni, Andrew Lees, John A Hardy, Michela A Denti, Alessandro Quattrone, Rickie Patani, Per Svenningsson, Thomas Treharne Warner, Vincent Plagnol, Jernej Ule, Rohan de Silva
MIR-NATs repress MAPT translation and aid proteostasis in neurodegeneration. Nature 594 (7861) (2021)
Colombine Verzat, Jasmine Harley, Rickie Patani, Raphaëlle Luisier
Image-based deep learning reveals the responses of human motor neurons to stress and VCP-related ALS. Neuropathology and applied neurobiology (2021)
Jasmine Harley, Cathleen Hagemann, Andrea Serio, Rickie Patani
TDP-43 and FUS mislocalization in VCP mutant motor neurons is reversed by pharmacological inhibition of the VCP D2 ATPase domain. Brain communications 3 (3) (2021)
Cathleen Hagemann, Giulia E Tyzack, Doaa M Taha, Helen Devine, Linda Greensmith, Jia Newcombe, Rickie Patani, Andrea Serio, Raphaëlle Luisier
Automated and unbiased discrimination of ALS from control tissue at single cell resolution. Brain pathology (Zurich, Switzerland) 31 (4) (2021)
Jasmine Harley, Benjamin E Clarke, Rickie Patani
The Interplay of RNA Binding Proteins, Oxidative Stress and Mitochondrial Dysfunction in ALS. Antioxidants (Basel, Switzerland) 10 (4) (2021)
Benjamin E Clarke, Doaa M Taha, Giulia E Tyzack, Rickie Patani
Regionally encoded functional heterogeneity of astrocytes in health and disease: A perspective. Glia 69 (1) (2020)
Jasmine Harley, Rickie Patani
Stress-Specific Spatiotemporal Responses of RNA-Binding Proteins in Human Stem-Cell-Derived Motor Neurons. International journal of molecular sciences 21 (21) (2020)
Marie A Brunet, Jean-Francois Jacques, Sonya Nassari, Giulia E Tyzack, Philip McGoldrick, Lorne Zinman, Steve Jean, Janice Robertson, Rickie Patani, Xavier Roucou
The FUS gene is dual-coding with both proteins contributing to FUS-mediated toxicity. EMBO reports 22 (1) (2020)
Yiran Wang, Rickie Patani
Novel therapeutic targets for amyotrophic lateral sclerosis: ribonucleoproteins and cellular autonomy. Expert opinion on therapeutic targets 24 (10) (2020)
Roberto Simone, Rubika Balendra, Thomas G Moens, Elisavet Preza, Katherine M Wilson, Amanda Heslegrave, Nathan S Woodling, Teresa Niccoli, Javier Gilbert-Jaramillo, Samir Abdelkarim, Emma L Clayton, Mica Clarke, Marie-Therese Konrad, Andrew J Nicoll, Jamie S Mitchell, Andrea Calvo, Adriano Chio, Henry Houlden, James M Polke, Mohamed A Ismail, Chad E Stephens, Tam Vo, Abdelbasset A Farahat, W David Wilson, David W Boykin, Henrik Zetterberg, Linda Partridge, Selina Wray, Gary Parkinson, Stephen Neidle, Rickie Patani, Pietro Fratta, Adrian M Isaacs
G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo. EMBO molecular medicine 10 (1) (2019)
Oliver Jonathan Ziff, Rickie Patani
Harnessing cellular aging in human stem cell models of amyotrophic lateral sclerosis. Aging cell 18 (1) (2018)
Andrea Serio, Rickie Patani
Concise Review: The Cellular Conspiracy of Amyotrophic Lateral Sclerosis. Stem cells (Dayton, Ohio) 36 (3) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Rickie Patani