Irene T Weber

ORCID

Publication Activity (10 Years)

Years Active: 2016-2021
Publications (10 Years): 9

Top Venues

Journal of medicinal chemistry

Biochemistry

PloS one

Viruses

Georgia State University

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Georgia State University

United States

Professor

Publications

Archana Iyer, Renata A G Reis, Swathi Gannavaram, Mohamed Momin, Alexander M Spring-Connell, Yoelvis Orozco-Gonzalez, Johnson Agniswamy, Donald Hamelberg, Irene T Weber, Samer Gozem, Siming Wang, Markus W Germann, Giovanni Gadda
A Single-Point Mutation in d-Arginine Dehydrogenase Unlocks a Transient Conformational State Resulting in Altered Cofactor Reactivity. Biochemistry 60 (9) (2021)
Irene T Weber, Yuan-Fang Wang, Robert W Harrison
HIV Protease: Historical Perspective and Current Research. Viruses 13 (5) (2021)
Daniel W Kneller, Johnson Agniswamy, Robert W Harrison, Irene T Weber
Highly drug-resistant HIV-1 protease reveals decreased intra-subunit interactions due to clusters of mutations. The FEBS journal 287 (15) (2020)
Arun K Ghosh, Satish Kovela, Heather L Osswald, Masayuki Amano, Manabu Aoki, Johnson Agniswamy, Yuan-Fang Wang, Irene T Weber, Hiroaki Mitsuya
Structure-Based Design of Highly Potent HIV-1 Protease Inhibitors Containing New Tricyclic Ring P2-Ligands: Design, Synthesis, Biological, and X-ray Structural Studies. Journal of medicinal chemistry 63 (9) (2020)
Arun K Ghosh, Prasanth R Nyalapatla, Satish Kovela, Kalapala Venkateswara Rao, Margherita Brindisi, Heather L Osswald, Masayuki Amano, Manabu Aoki, Johnson Agniswamy, Yuan-Fang Wang, Irene T Weber, Hiroaki Mitsuya
Design and Synthesis of Highly Potent HIV-1 Protease Inhibitors Containing Tricyclic Fused Ring Systems as Novel P2 Ligands: Structure-Activity Studies, Biological and X-ray Structural Analysis. Journal of medicinal chemistry 61 (10) (2018)
Arun K Ghosh, Jacqueline N Williams, Rachel Y Ho, Hannah M Simpson, Shin-Ichiro Hattori, Hironori Hayashi, Johnson Agniswamy, Yuan-Fang Wang, Irene T Weber, Hiroaki Mitsuya
Design and Synthesis of Potent HIV-1 Protease Inhibitors Containing Bicyclic Oxazolidinone Scaffold as the P2 Ligands: Structure-Activity Studies and Biological and X-ray Structural Studies. Journal of medicinal chemistry 61 (21) (2018)
Arun K Ghosh, Kalapala Venkateswara Rao, Prasanth R Nyalapatla, Heather L Osswald, Cuthbert D Martyr, Manabu Aoki, Hironori Hayashi, Johnson Agniswamy, Yuan-Fang Wang, Haydar Bulut, Debananda Das, Irene T Weber, Hiroaki Mitsuya
Design and Development of Highly Potent HIV-1 Protease Inhibitors with a Crown-Like Oxotricyclic Core as the P2-Ligand To Combat Multidrug-Resistant HIV Variants. Journal of medicinal chemistry 60 (10) (2017)
Oksana Gerlits, David A Keen, Matthew P Blakeley, John M Louis, Irene T Weber, Andrey Y Kovalevsky
Room Temperature Neutron Crystallography of Drug Resistant HIV-1 Protease Uncovers Limitations of X-ray Structural Analysis at 100 K. Journal of medicinal chemistry 60 (5) (2017)
Johnson Agniswamy, John M Louis, Julien Roche, Robert W Harrison, Irene T Weber
Structural Studies of a Rationally Selected Multi-Drug Resistant HIV-1 Protease Reveal Synergistic Effect of Distal Mutations on Flap Dynamics. PloS one 11 (12) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Irene T Weber