Matthew P Blakeley (Matthew Blakeley)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 18

Top Venues

Nature communications

IUCrJ

Research square

Communications chemistry

Institut Laue-Langevin

University of Manchester (BSC)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Institut Laue-Langevin Jan 01 2007

France

Research scientist :: Large Scale Structures group

EMBL Oct 01 2003 - Dec 31 2006

France

Post-doctoral research scientist :: Neutron diffraction group

Education History

University of Manchester Sep 01 1996 - Jun 01 1999

United Kingdom

BSC :: Chemistry

Publications

Victoria N Drago, Claudia Campos, Mattea Hooper, Aliyah Collins, Oksana Gerlits, Kevin L Weiss, Matthew P Blakeley, Robert S Phillips, Andrey Y Kovalevsky
Revealing protonation states and tracking substrate in serine hydroxymethyltransferase with room-temperature X-ray and neutron crystallography. Communications chemistry 6 (1) (2023)
H V Sørensen, Mateu Montserrat-Canals, Jennifer S M Loose, S Zoë Fisher, Martine Moulin, Matthew P Blakeley, Gabriele Cordara, Kaare Bjerregaard-Andersen, Ute Krengel
Perdeuterated GbpA Enables Neutron Scattering Experiments of a Lytic Polysaccharide Monooxygenase. ACS omega 8 (32) (2023)
Lukas Gajdos, Matthew P Blakeley, Michael Haertlein, V Trevor Forsyth, Juliette M Devos, Anne Imberty
Neutron crystallography reveals mechanisms used by Pseudomonas aeruginosa for host-cell binding. Nature communications 13 (1) (2022)
Victoria N Drago, Steven Dajnowicz, Jerry M Parks, Matthew P Blakeley, David A Keen, Nicolas Coquelle, Kevin L Weiss, Oksana Gerlits, Andrey Y Kovalevsky, Timothy C Mueser
An N⋯H⋯N low-barrier hydrogen bond preorganizes the catalytic site of aspartate aminotransferase to facilitate the second half-reaction. Chemical science 13 (34) (2022)
Victoria N Drago, Juliette M Devos, Matthew P Blakeley, V Trevor Forsyth, Andrey Y Kovalevsky, Constance A Schall, Timothy C Mueser
Microgravity crystallization of perdeuterated tryptophan synthase for neutron diffraction. NPJ microgravity 8 (1) (2022)
Daniel Kneller, Hui Li, Gwyndalyn Phillips, Kevin L Weiss, Qiu Zhang, Mark A Arnould, Colleen Jonsson, Surekha Surendranathan, Jyothi Parvathareddy, Matthew P Blakeley, Leighton Coates, John M Louis, Peter V Bonnesen, Andrey Y Kovalevsky
Covalent narlaprevir- and boceprevir-derived hybrid inhibitors of SARS-CoV-2 main protease: room-temperature X-ray and neutron crystallography, binding thermodynamics, and antiviral activity. Research square (2022)
Daniel W Kneller, Hui Li, Gwyndalyn Phillips, Kevin L Weiss, Qiu Zhang, Mark A Arnould, Colleen B Jonsson, Surekha Surendranathan, Jyothi Parvathareddy, Matthew P Blakeley, Leighton Coates, John M Louis, Peter V Bonnesen, Andrey Y Kovalevsky
Covalent narlaprevir- and boceprevir-derived hybrid inhibitors of SARS-CoV-2 main protease. Nature communications 13 (1) (2022)
Vinardas Kelpšas, Octav Caldararu, Matthew P Blakeley, Nicolas Coquelle, Rikkert K Wierenga, Ulf Ryde, Claes von Wachenfeldt, Esko Oksanen
Neutron structures of Leishmania mexicana triosephosphate isomerase in complex with reaction-intermediate mimics shed light on the proton-shuttling steps. IUCrJ 8 (Pt 4) (2021)
Lindsay McGregor, Tamás Földes, Soi Bui, Martine Moulin, Nicolas Coquelle, Matthew P Blakeley, Edina Rosta, Roberto A Steiner
Joint neutron/X-ray crystal structure of a mechanistically relevant complex of perdeuterated urate oxidase and simulations provide insight into the hydration step of catalysis. IUCrJ 8 (Pt 1) (2021)
Hanna Kwon, Jaswir Basran, Juliette M Devos, Reynier Suardíaz, Marc W van der Kamp, Adrian J Mulholland, Tobias E Schrader, Andreas Ostermann, Matthew P Blakeley, Peter C E Moody, Emma L Raven
Visualizing the protons in a metalloenzyme electron proton transfer pathway. Proceedings of the National Academy of Sciences of the United States of America 117 (12) (2020)
Vinardas Kelpšas, Bénédicte Lafumat, Matthew P Blakeley, Nicolas Coquelle, Esko Oksanen, Claes von Wachenfeldt
Perdeuteration, large crystal growth and neutron data collection of Leishmania mexicana triose-phosphate isomerase E65Q variant. Acta crystallographica. Section F, Structural biology communications 75 (Pt 4) (2019)
Thomas P Halsted, Keitaro Yamashita, Chai C Gopalasingam, Rajesh T Shenoy, Kunio Hirata, Hideo Ago, Go Ueno, Matthew P Blakeley, Robert R Eady, Svetlana V Antonyuk, Masaki Yamamoto, S Samar Hasnain
Catalytically important damage-free structures of a copper nitrite reductase obtained by femtosecond X-ray laser and room-temperature neutron crystallography. IUCrJ 6 (Pt 4) (2019)
Ai Woon Yee, Matteo Aldeghi, Matthew P Blakeley, Andreas Ostermann, Philippe J Mas, Martine Moulin, Daniele de Sanctis, Matthew W Bowler, Christoph Mueller-Dieckmann, Edward P Mitchell, Michael Haertlein, Bert L de Groot, Elisabetta Boeri Erba, V Trevor Forsyth
A molecular mechanism for transthyretin amyloidogenesis. Nature communications 10 (1) (2019)
Oksana Gerlits, Kevin L Weiss, Matthew P Blakeley, Gianluigi Veglia, Susan S Taylor, Andrey Y Kovalevsky
Zooming in on protons: Neutron structure of protein kinase A trapped in a product complex. Science advances 5 (3) (2019)
Ai Woon Yee, Matthew P Blakeley, Martine Moulin, Michael Haertlein, Edward Mitchell, V Trevor Forsyth
Back-exchange of deuterium in neutron crystallography: characterization by IR spectroscopy. Journal of applied crystallography 50 (Pt 2) (2017)
Oksana Gerlits, David A Keen, Matthew P Blakeley, John M Louis, Irene T Weber, Andrey Y Kovalevsky
Room Temperature Neutron Crystallography of Drug Resistant HIV-1 Protease Uncovers Limitations of X-ray Structural Analysis at 100 K. Journal of medicinal chemistry 60 (5) (2017)
Steven Dajnowicz, Ryne C Johnston, Jerry M Parks, Matthew P Blakeley, David A Keen, Kevin L Weiss, Oksana Gerlits, Andrey Y Kovalevsky, Timothy C Mueser
Direct visualization of critical hydrogen atoms in a pyridoxal 5'-phosphate enzyme. Nature communications 8 (1) (2017)
Hanna Kwon, Jaswir Basran, Cecilia M Casadei, Alistair J Fielding, Tobias E Schrader, Andreas Ostermann, Juliette M Devos, Pierre Aller, Matthew P Blakeley, Peter C E Moody, Emma L Raven
Direct visualization of a Fe(IV)-OH intermediate in a heme enzyme. Nature communications 7 (2016)

Matthew P Blakeley.css-eqlu8i{font-size:small;padding-left:4px;} (Matthew Blakeley)

Publication Activity (10 Years)

Top Topics

Top Venues

Matthew P Blakeley (Matthew Blakeley)