Irmgard Sinning

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 49

Top Topics

Listeria Monocytogenes

Structural Basis

Top Venues

Nature communications

Nature structural & molecular biology

Genome research

This page only lists publications with an associated author ORCID identifier.

Publications

Valentin Bohl, Nele Merret Hollmann, Tobias Melzer, Panagiotis Katikaridis, Lena Meins, Bernd Simon, Dirk Flemming, Irmgard Sinning, Janosch Hennig, Axel Mogk
The Listeria monocytogenes persistence factor ClpL is a potent stand-alone disaggregase. eLife 12 (2024)
Laura Armbruster, Marlena Pożoga, Zhongshou Wu, Jürgen Eirich, Karen Thulasi Devendrakumar, Carolina de la Torre, Pavlína Miklánková, Monika Huber, Fabian Bradic, Gernot Poschet, Jonas Weidenhausen, Sabine Merker, Thomas Ruppert, Carsten Sticht, Irmgard Sinning, Iris Finkemeier, Xin Li, Ruediger Hell, Ruediger Hell
Nα-acetyltransferase NAA50 mediates plant immunity independent of the Nα-acetyltransferase A complex. Plant physiology 195 (4) (2024)
Valentin Bohl, Nele Merret Hollmann, Tobias Melzer, Panagiotis Katikaridis, Lena Meins, Bernd Simon, Dirk Flemming, Irmgard Sinning, Janosch Hennig, Axel Mogk
The Listeria monocytogenes persistence factor ClpL is a potent stand-alone disaggregase. eLife 12 (2024)
Laura Armbruster, Marlena Pożoga, Zhongshou Wu, Jürgen Eirich, Karen Thulasi Devendrakumar, Carolina de la Torre, Pavlína Miklánková, Monika Huber, Fabian Bradic, Gernot Poschet, Jonas Weidenhausen, Sabine Merker, Thomas Ruppert, Carsten Sticht, Irmgard Sinning, Iris Finkemeier, Xin Li, Ruediger Hell, Ruediger Hell
Nα-acetyltransferase NAA50 mediates plant immunity independent of the Nα-acetyltransferase A complex. Plant physiology (2024)
Marius A Klein, Klemens Wild, Miglė Kišonaitė, Irmgard Sinning
Methionine aminopeptidase 2 and its autoproteolysis product have different binding sites on the ribosome. Nature communications 15 (1) (2024)
Marius Klein, Klemens Wild, Irmgard Sinning
Multi-protein assemblies orchestrate co-translational enzymatic processing on the human ribosome. Nature communications 15 (1) (2024)
Alexander Hirth, Edoardo Fatti, Eugen Netz, Sergio P Acebron, Dimitris Papageorgiou, Andrea Švorinić, Cristina-Maria Cruciat, Emil Karaulanov, Alexandr Gopanenko, Tianheng Zhu, Irmgard Sinning, Jeroen Krijgsveld, Oliver Kohlbacher, Christof Niehrs
DEAD box RNA helicases are pervasive protein kinase interactors and activators. Genome research (2024)
Marius A Klein, Klemens Wild, Miglė Kišonaitė, Irmgard Sinning
Methionine aminopeptidase 2 and its autoproteolysis product have different binding sites on the ribosome. Nature communications 15 (1) (2024)
Alexander Hirth, Edoardo Fatti, Eugen Netz, Sergio P Acebron, Dimitris Papageorgiou, Andrea Švorinić, Cristina-Maria Cruciat, Emil Karaulanov, Alexandr Gopanenko, Tianheng Zhu, Irmgard Sinning, Jeroen Krijgsveld, Oliver Kohlbacher, Christof Niehrs
DEAD box RNA helicases are pervasive protein kinase interactors and activators. Genome research 34 (6) (2024)
Valentin Bohl, Nele Merret Hollmann, Tobias Melzer, Panagiotis Katikaridis, Lena Meins, Bernd Simon, Dirk Flemming, Irmgard Sinning, Janosch Hennig, Axel Mogk
The Listeria monocytogenes persistence factor ClpL is a potent stand-alone disaggregase. eLife 12 (2024)
Laura Armbruster, Marlena Pożoga, Zhongshou Wu, Jürgen Eirich, Karen Thulasi Devendrakumar, Carolina de la Torre, Pavlína Miklánková, Monika Huber, Fabian Bradic, Gernot Poschet, Jonas Weidenhausen, Sabine Merker, Thomas Ruppert, Carsten Sticht, Irmgard Sinning, Iris Finkemeier, Xin Li, Ruediger Hell, Ruediger Hell
Nα-acetyltransferase NAA50 mediates plant immunity independent of the Nα-acetyltransferase A complex. Plant physiology 195 (4) (2024)
Alexander Hirth, Edoardo Fatti, Eugen Netz, Sergio P Acebron, Dimitris Papageorgiou, Andrea Švorinić, Cristina-Maria Cruciat, Emil Karaulanov, Alexandr Gopanenko, Tianheng Zhu, Irmgard Sinning, Jeroen Krijgsveld, Oliver Kohlbacher, Christof Niehrs
DEAD box RNA helicases are pervasive protein kinase interactors and activators. Genome research 34 (6) (2024)
Alexander Hirth, Edoardo Fatti, Eugen Netz, Sergio P Acebron, Dimitris Papageorgiou, Andrea Švorinić, Cristina-Maria Cruciat, Emil Karaulanov, Alexandr Gopanenko, Tianheng Zhu, Irmgard Sinning, Jeroen Krijgsveld, Oliver Kohlbacher, Christof Niehrs
DEAD box RNA helicases are pervasive protein kinase interactors and activators. Genome research 34 (6) (2024)
Marius Klein, Klemens Wild, Irmgard Sinning
Multi-protein assemblies orchestrate co-translational enzymatic processing on the human ribosome. Nature communications 15 (1) (2024)
Valentin Bohl, Nele Merret Hollmann, Tobias Melzer, Panagiotis Katikaridis, Lena Meins, Bernd Simon, Dirk Flemming, Irmgard Sinning, Janosch Hennig, Axel Mogk
The Listeria monocytogenes persistence factor ClpL is a potent stand-alone disaggregase. eLife 12 (2024)
Marius A Klein, Klemens Wild, Miglė Kišonaitė, Irmgard Sinning
Methionine aminopeptidase 2 and its autoproteolysis product have different binding sites on the ribosome. Nature communications 15 (1) (2024)
Valentin Bohl, Nele Merret Hollmann, Tobias Melzer, Panagiotis Katikaridis, Lena Meins, Bernd Simon, Dirk Flemming, Irmgard Sinning, Janosch Hennig, Axel Mogk
The Listeria monocytogenes persistence factor ClpL is a potent stand-alone disaggregase. eLife 12 (2024)
Miglė Kišonaitė, Klemens Wild, Karine Lapouge, Genís Valentín Gesé, Nikola Kellner, Ed Hurt, Irmgard Sinning
Structural inventory of cotranslational protein folding by the eukaryotic RAC complex. Nature structural & molecular biology (2023)
Komal Soni, Anusree Sivadas, Attila Horvath, Nikolay Dobrev, Rippei Hayashi, Leo Kiss, Bernd Simon, Klemens Wild, Irmgard Sinning, Tamas Fischer
Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex. Nature communications 14 (1) (2023)
Edoardo Fatti, Alexander Hirth, Andrea Švorinić, Matthias Günther, Gunter Stier, Cristina-Maria Cruciat, Sergio P Acebrón, Dimitris Papageorgiou, Irmgard Sinning, Jeroen Krijgsveld, Thomas Höfer, Christof Niehrs
DEAD box RNA helicases act as nucleotide exchange factors for casein kinase 2. Science signaling 16 (782) (2023)
Miglė Kišonaitė, Klemens Wild, Karine Lapouge, Genís Valentín Gesé, Nikola Kellner, Ed Hurt, Irmgard Sinning
Structural inventory of cotranslational protein folding by the eukaryotic RAC complex. Nature structural & molecular biology (2023)
Edoardo Fatti, Alexander Hirth, Andrea Švorinić, Matthias Günther, Gunter Stier, Cristina-Maria Cruciat, Sergio P Acebrón, Dimitris Papageorgiou, Irmgard Sinning, Jeroen Krijgsveld, Thomas Höfer, Christof Niehrs
DEAD box RNA helicases act as nucleotide exchange factors for casein kinase 2. Science signaling 16 (782) (2023)
Miglė Kišonaitė, Klemens Wild, Karine Lapouge, Genís Valentín Gesé, Nikola Kellner, Ed Hurt, Irmgard Sinning
Structural inventory of cotranslational protein folding by the eukaryotic RAC complex. Nature structural & molecular biology 30 (5) (2023)
Komal Soni, Anusree Sivadas, Attila Horvath, Nikolay Dobrev, Rippei Hayashi, Leo Kiss, Bernd Simon, Klemens Wild, Irmgard Sinning, Tamas Fischer
Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex. Nature communications 14 (1) (2023)
Miglė Kišonaitė, Klemens Wild, Karine Lapouge, Genís Valentín Gesé, Nikola Kellner, Ed Hurt, Irmgard Sinning
Structural inventory of cotranslational protein folding by the eukaryotic RAC complex. Nature structural & molecular biology (2023)
Leo Kiss, Tyler Rhinesmith, Jakub Luptak, Claire F Dickson, Jonas Weidenhausen, Shannon Smyly, Ji-Chun Yang, Sarah L Maslen, Irmgard Sinning, David Neuhaus, Dean Clift, Leo C James
Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates. Nature communications 14 (1) (2023)
Miglė Kišonaitė, Klemens Wild, Karine Lapouge, Genís Valentín Gesé, Nikola Kellner, Ed Hurt, Irmgard Sinning
Structural inventory of cotranslational protein folding by the eukaryotic RAC complex. Nature structural & molecular biology (2023)
Komal Soni, Anusree Sivadas, Attila Horvath, Nikolay Dobrev, Rippei Hayashi, Leo Kiss, Bernd Simon, Klemens Wild, Irmgard Sinning, Tamas Fischer
Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex. Nature communications 14 (1) (2023)
Miglė Kišonaitė, Klemens Wild, Karine Lapouge, Genís Valentín Gesé, Nikola Kellner, Ed Hurt, Irmgard Sinning
Structural inventory of cotranslational protein folding by the eukaryotic RAC complex. Nature structural & molecular biology 30 (5) (2023)
Miglė Kišonaitė, Klemens Wild, Karine Lapouge, Genís Valentín Gesé, Nikola Kellner, Ed Hurt, Irmgard Sinning
Structural inventory of cotranslational protein folding by the eukaryotic RAC complex. Nature structural & molecular biology 30 (5) (2023)
Melanie A McDowell, Michael Heimes, Giray Enkavi, Ákos Farkas, Daniel Saar, Klemens Wild, Blanche Schwappach, Ilpo Vattulainen, Irmgard Sinning
The GET insertase exhibits conformational plasticity and induces membrane thinning. Nature communications 14 (1) (2023)
Komal Soni, Anusree Sivadas, Attila Horvath, Nikolay Dobrev, Rippei Hayashi, Leo Kiss, Bernd Simon, Klemens Wild, Irmgard Sinning, Tamas Fischer
Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex. Nature communications 14 (1) (2023)
Komal Soni, Anusree Sivadas, Attila Horvath, Nikolay Dobrev, Rippei Hayashi, Leo Kiss, Bernd Simon, Klemens Wild, Irmgard Sinning, Tamas Fischer
Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex. Nature communications 14 (1) (2023)
Jonas Weidenhausen, Jürgen Kopp, Carmen Ruger-Herreros, Frank Stein, Per Haberkant, Karine Lapouge, Irmgard Sinning
Extended N-Terminal Acetyltransferase Naa50 in Filamentous Fungi Adds to Naa50 Diversity. International journal of molecular sciences 23 (18) (2022)
Pavlína Miklánková, Eric Linster, Jean-Baptiste Boyer, Jonas Weidenhausen, Johannes B Müller, Laura Armbruster, Karine Lapouge, Carolina de la Torre, Willy V Bienvenut, Carsten Sticht, Matthias Mann, Thierry Meinnel, Irmgard Sinning, Carmela Giglione, Ruediger Hell, Ruediger Hell
HYPK promotes the activity of the N α -acetyltransferase A complex to determine proteostasis of nonAc-X 2 /N-degron-containing proteins. Science advances 8 (24) (2022)
Miglė Kišonaitė, Klemens Wild, Karine Lapouge, Thomas Ruppert, Irmgard Sinning
High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation. Nature communications 13 (1) (2022)
Lucía Martín Caballero, Matías Capella, Ramón Ramos Barrales, Nikolay Dobrev, Thomas S van Emden, Yasuhiro Hirano, Vishnu N Suma Sreechakram, Sabine Fischer-Burkart, Yasuha Kinugasa, Alicia Nevers, Mathieu Rougemaille, Irmgard Sinning, Tamas Fischer, Yasushi Hiraoka, Sigurd Braun
The inner nuclear membrane protein Lem2 coordinates RNA degradation at the nuclear periphery. Nature structural & molecular biology 29 (9) (2022)
Dominik Layer, Jürgen Kopp, Miriam Fontanillo, Maja Köhn, Karine Lapouge, Irmgard Sinning
Structural basis of Naa20 activity towards a canonical NatB substrate. Communications biology 4 (1) (2021)
Melanie A McDowell, Michael Heimes, Irmgard Sinning
Structural and molecular mechanisms for membrane protein biogenesis by the Oxa1 superfamily. Nature structural & molecular biology 28 (3) (2021)
Komal Soni, Georg Kempf, Karen Manalastas-Cantos, Astrid Hendricks, Dirk Flemming, Julien Guizetti, Bernd Simon, Friedrich Frischknecht, Dmitri I Svergun, Klemens Wild, Irmgard Sinning
Structural analysis of the SRP Alu domain from Plasmodium falciparum reveals a non-canonical open conformation. Communications biology 4 (1) (2021)
Nikolay Dobrev, Yasar Luqman Ahmed, Anusree Sivadas, Komal Soni, Tamas Fischer, Irmgard Sinning
The zinc-finger protein Red1 orchestrates MTREC submodules and binds the Mtl1 helicase arch domain. Nature communications 12 (1) (2021)
Jeremy Sloan, Jana P Hakenjos, Michael Gebert, Olga Ermakova, Andrea Gumiero, Gunter Stier, Klemens Wild, Irmgard Sinning, Jan U Lohmann
Structural basis for the complex DNA binding behavior of the plant stem cell regulator WUSCHEL. Nature communications 11 (1) (2020)
Eric Linster, Dominik Layer, Willy V Bienvenut, Trinh V Dinh, Felix A Weyer, Wiebke Leemhuis, Annika Brünje, Marion Hoffrichter, Pavlína Miklánková, Jürgen Kopp, Karine Lapouge, Julia Sindlinger, Dirk Schwarzer, Thierry Meinnel, Iris Finkemeier, Carmela Giglione, Ruediger Hell, Irmgard Sinning, Ruediger Hell
The Arabidopsis Nα -acetyltransferase NAA60 locates to the plasma membrane and is vital for the high salt stress response. The New phytologist 228 (2) (2020)
Klemens Wild, Milan Aleksić, Karine Lapouge, Keven D Juaire, Dirk Flemming, Stefan Pfeffer, Irmgard Sinning
MetAP-like Ebp1 occupies the human ribosomal tunnel exit and recruits flexible rRNA expansion segments. Nature communications 11 (1) (2020)
Antonella Chiapparino, Antonija Grbavac, Hendrik R A Jonker, Yvonne Hackmann, Sofia Mortensen, Ewa Zatorska, Andrea Schott, Gunter Stier, Krishna Saxena, Klemens Wild, Harald Schwalbe, Natalie Rinis, Irmgard Sinning
Functional implications of MIR domains in protein O-mannosylation. eLife 9 (2020)
Laura Armbruster, Eric Linster, Jean-Baptiste Boyer, Annika Brünje, Jürgen Eirich, Iwona Stephan, Willy V Bienvenut, Jonas Weidenhausen, Thierry Meinnel, Ruediger Hell, Irmgard Sinning, Iris Finkemeier, Carmela Giglione, Ruediger Hell
NAA50 Is an Enzymatically Active N α-Acetyltransferase That Is Crucial for Development and Regulation of Stress Responses. Plant physiology 183 (4) (2020)
Ying Zhang, Genis Valentin Gese, Charlotte Conz, Karine Lapouge, Jürgen Kopp, Tina Wölfle, Sabine Rospert, Irmgard Sinning
The ribosome-associated complex RAC serves in a relay that directs nascent chains to Ssb. Nature communications 11 (1) (2020)
Yasar Luqman Ahmed, Matthias Thoms, Valentin Mitterer, Irmgard Sinning, Ed Hurt
Crystal structures of Rea1-MIDAS bound to its ribosome assembly factor ligands resembling integrin-ligand-type complexes. Nature communications 10 (1) (2019)
Fabiola R Calviño, Markus Kornprobst, Géza Schermann, Fabienne Birkle, Klemens Wild, Tamas Fischer, Ed Hurt, Yasar Luqman Ahmed, Irmgard Sinning
Structural basis for 5'-ETS recognition by Utp4 at the early stages of ribosome biogenesis. PloS one 12 (6) (2017)