Jean M Fletcher (J M Fletcher)

Scopus Author ID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 14

Top Venues

The British journal of dermatology

International journal of molecular sciences

Clinical and experimental immunology

Journal of immunology (Baltimore, Md. : 1950)

Trinity College Dublin

University of London (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Trinity College Dublin

Ireland

Assistant Professor in Translational Immunology :: Schhol of Medicine/School of Biochemistry and Immunology

University of Dublin Trinity College

Ireland

SFI SIRG PI :: School of Biochemistry and Immunology

University of Dublin Trinity College

Ireland

HRB Research Fellow :: School of Biochemistry and Immunology

University College Dublin

Ireland

Post Doctoral Researcher

Education History

University of London

United Kingdom

PHD :: Royal Free Hospital UCL

University of Cape Town Medical School

South Africa

MSC :: Clinical Immunology

University of Cape Town

South Africa

BSC :: Biochemistry

University of Cape Town

South Africa

BSC :: Biochemistry and Microbiology

Publications

Adina N MacMahon Copas, Sarah F McComish, Andreea Petrasca, Rachel McCormack, Daniel Ivers, Anna Stricker, Jean M Fletcher, Maeve A Caldwell
CD4 + T cell-associated cytokines induce a chronic pro-inflammatory phenotype in induced pluripotent stem cell-derived midbrain astrocytes. Glia (2024)
Ciara Campbell, Jay M Mayatra, Ashish J Neve, Jean M Fletcher, Daniel G W Johnston
Inflammasomes: emerging therapeutic targets in hidradenitis suppurativa? The British journal of dermatology (2024)
Barry Moran, Conor M Smith, Alexandra Zabarowski, Mark Ryan, Jozsef Karman, Robert W Dunstan, Kathleen M Smith, Roisin Hambly, Jana Musilova, Andreea Petrasca, Aurelie Fabre, Margaret O'Donnell, Karsten Hokamp, Kingston H G Mills, William J Housley, Desmond C Winter, Brian Kirby, Jean M Fletcher
Targeting the NLRP3 inflammasome reduces inflammation in hidradenitis suppurativa skin. The British journal of dermatology (2023)
Roisin A Hambly, Solene Gatault, Conor M Smith, Luis F Iglesias-Martinez, Sean Kearns, Helen Rea, Vivien Marasigan, Kate Lynam-Loane, Shivashini Kirthi, Rosalind Hughes, Jean M Fletcher, Walter Kolch, Brian Kirby
B-cell and complement signature in severe hidradenitis suppurativa that does not respond to adalimumab. The British journal of dermatology 188 (1) (2023)
Roisin A Hambly, Niamh Kearney, Rosalind Hughes, Jean M Fletcher, Brian Kirby
Metformin Treatment of Hidradenitis Suppurativa: Effect on Metabolic Parameters, Inflammation, Cardiovascular Risk Biomarkers, and Immune Mediators. International journal of molecular sciences 24 (8) (2023)
Roisin A Hambly, Niamh Kearney, Rosalind Hughes, Jean M Fletcher, Brian Kirby
Metformin Treatment of Hidradenitis Suppurativa: Effect on Metabolic Parameters, Inflammation, Cardiovascular Risk Biomarkers, and Immune Mediators. International journal of molecular sciences 24 (8) (2023)
Conor M Smith, Roisin A Hambly, Solene Gatault, Luis F Iglesias-Martinez, Sean Kearns, Helen Rea, Vivien Marasigan, Kate Lynam-Loane, Shivashini Kirthi, Rosalind Hughes, Jean M Fletcher, Walter Kolch, Brian Kirby
B-cell-derived transforming growth factor-β may drive the activation of inflammatory macrophages and contribute to scarring in hidradenitis suppurativa. The British journal of dermatology 188 (2) (2023)
Conor M Smith, Roisin A Hambly, Solene Gatault, Luis F Iglesias-Martinez, Sean Kearns, Helen Rea, Vivien Marasigan, Kate Lynam-Loane, Shivashini Kirthi, Rosalind Hughes, Jean M Fletcher, Walter Kolch, Brian Kirby
B-cell-derived transforming growth factor-β may drive the activation of inflammatory macrophages and contribute to scarring in hidradenitis suppurativa. The British journal of dermatology 188 (2) (2023)
Roisin A Hambly, Niamh Kearney, Rosalind Hughes, Jean M Fletcher, Brian Kirby
Metformin Treatment of Hidradenitis Suppurativa: Effect on Metabolic Parameters, Inflammation, Cardiovascular Risk Biomarkers, and Immune Mediators. International journal of molecular sciences 24 (8) (2023)
Andreea Petrasca, Roisin A Hambly, Niamh Kearney, Conor M Smith, Emily K Pender, Julie Mac Mahon, Aoife M O'Rourke, Mohamed Ismaiel, Patrick A Boland, Jose P Almeida, Czara A Kennedy, Alexandra Zaborowski, Siun Murphy, Desmond Winter, Brian Kirby, Jean M Fletcher
Metformin has anti-inflammatory effects and induces immunometabolic reprogramming in hidradenitis suppurativa via multiple mechanisms. The British journal of dermatology (2023)
Brian Kirby, Jean M Fletcher
Mechanism of action of dimethyl fumarate: a small molecule with big effects. The British journal of dermatology 185 (3) (2021)
Jean M Fletcher, B Moran, Andreea Petrasca, Conor M Smith
IL-17 in inflammatory skin diseases psoriasis and hidradenitis suppurativa. Clinical and experimental immunology 201 (2) (2020)
J Sulaimani, D Cluxton, Julianne Clowry, Andreea Petrasca, Oonagh Molloy, B Moran, C M Sweeney, Anna Malara, Nuala McNicholas, C McGuigan, Brian Kirby, Jean M Fletcher
Dimethyl fumarate modulates the Treg-Th17 cell axis in patients with psoriasis. The British journal of dermatology 184 (3) (2020)
Sharee A Basdeo, Deborah Cluxton, Jamal Sulaimani, Barry Moran, Mary Canavan, Carl Orr, Douglas J Veale, Ursula Fearon, Jean M Fletcher
Ex-Th17 (Nonclassical Th1) Cells Are Functionally Distinct from Classical Th1 and Th17 Cells and Are Not Constrained by Regulatory T Cells. Journal of immunology (Baltimore, Md. : 1950) 198 (6) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Jean M Fletcher (J M Fletcher)