Jacob G Scott (Jacob Scott, J Scott)

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 44

Top Venues

bioRxiv : the preprint server for biology

PLoS computational biology

Proceedings of the National Academy of Sciences of the United States of America

Nature communications

Cleveland Clinic

US Naval Academy (BSC)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Cleveland Clinic Aug 08 2016

United States

Associate Staff :: Translational Hematology and Oncology Research

Education History

US Naval Academy Jun 01 1994 - May 23 1998

United States

BSC :: Physics

Publications

Davis T Weaver, Eshan S King, Jeff Maltas, Jacob G Scott
Reinforcement learning informs optimal treatment strategies to limit antibiotic resistance. Proceedings of the National Academy of Sciences of the United States of America 121 (16) (2024)
Eshan S King, Dagim S Tadele, Beck Pierce, Michael Hinczewski, Jacob G Scott
Diverse mutant selection windows shape spatial heterogeneity in evolving populations. PLoS computational biology 20 (2) (2024)
Davis T Weaver, Eshan S King, Jeff Maltas, Jacob G Scott
Reinforcement learning informs optimal treatment strategies to limit antibiotic resistance. Proceedings of the National Academy of Sciences of the United States of America 121 (16) (2024)
Davis T Weaver, Eshan S King, Jeff Maltas, Jacob G Scott
Reinforcement learning informs optimal treatment strategies to limit antibiotic resistance. Proceedings of the National Academy of Sciences of the United States of America 121 (16) (2024)
Eshan S King, Dagim S Tadele, Beck Pierce, Michael Hinczewski, Jacob G Scott
Diverse mutant selection windows shape spatial heterogeneity in evolving populations. PLoS computational biology 20 (2) (2024)
Davis T Weaver, Eshan S King, Jeff Maltas, Jacob G Scott
Reinforcement learning informs optimal treatment strategies to limit antibiotic resistance. Proceedings of the National Academy of Sciences of the United States of America 121 (16) (2024)
Eshan S King, Dagim S Tadele, Beck Pierce, Michael Hinczewski, Jacob G Scott
Diverse mutant selection windows shape spatial heterogeneity in evolving populations. PLoS computational biology 20 (2) (2024)
Eshan S King, Dagim S Tadele, Beck Pierce, Michael Hinczewski, Jacob G Scott
Diverse mutant selection windows shape spatial heterogeneity in evolving populations. PLoS computational biology 20 (2) (2024)
Bina Desai, Tatiana Miti, Sandhya Prabhakaran, Daria Miroshnychenko, Menkara Henry, Viktoriya Marusyk, Chandler D Gatenbee, Marilyn M Bui, Jacob G Scott, Philipp M Altrock, Eric B Haura, Alexander A R A Anderson, David Basanta, Andriy Marusyk
Peristromal niches protect lung cancers from targeted therapies through a combined effect of multiple molecular mediators. bioRxiv : the preprint server for biology (2024)
Eshan S King, Anna E Stacy, Jacob G Scott
A low-footprint, fluorescence-based bacterial time-kill assay for estimating dose-dependent cell death dynamics. bioRxiv : the preprint server for biology (2024)
Davis T Weaver, Eshan S King, Jeff Maltas, Jacob G Scott
Reinforcement learning informs optimal treatment strategies to limit antibiotic resistance. Proceedings of the National Academy of Sciences of the United States of America 121 (16) (2024)
Davis T Weaver, Eshan S King, Jeff Maltas, Jacob G Scott
Reinforcement learning informs optimal treatment strategies to limit antibiotic resistance. Proceedings of the National Academy of Sciences of the United States of America 121 (16) (2024)
Eshan S King, Anna E Stacy, Jacob G Scott
A low-footprint, fluorescence-based bacterial time-kill assay for estimating dose-dependent cell death dynamics. bioRxiv : the preprint server for biology (2024)
Eshan S King, Dagim S Tadele, Beck Pierce, Michael Hinczewski, Jacob G Scott
Diverse mutant selection windows shape spatial heterogeneity in evolving populations. PLoS computational biology 20 (2) (2024)
Davis T Weaver, Jeff A Maltas, Jacob G Scott
Reinforcement Learning informs optimal treatment strategies to limit antibiotic resistance. bioRxiv : the preprint server for biology (2023)
Jessica A Scarborough, Steven A Eschrich, Javier Torres-Roca, Andrew Dhawan, Jacob G Scott
Exploiting convergent phenotypes to derive a pan-cancer cisplatin response gene expression signature. NPJ precision oncology 7 (1) (2023)
Mina N Dinh, Masahiro Hitomi, Zahraa A Al-Turaihi, Jacob G Scott
Alamar Blue assay optimization to minimize drug interference and inter-assay viability. bioRxiv : the preprint server for biology (2023)
Davis T Weaver, Jeff A Maltas, Jacob G Scott
Reinforcement Learning informs optimal treatment strategies to limit antibiotic resistance. bioRxiv : the preprint server for biology (2023)
Eashwar Somasundaram, Raoul R Wadhwa, Adam Litzler, Rowan Barker-Clarke, Peng Qi, Gregory M M Videtic, Kevin Stephans, Nathan A Pennell, Daniel P Raymond, Kailin Yang, Michael W Kattan, Jacob G Scott
Clinical Nomogram Using Novel Computed Tomography-Based Radiomics Predicts Survival in Patients With Non-Small-Cell Lung Cancer Treated With Stereotactic Body Radiation Therapy. JCO clinical cancer informatics 7 (2023)
Rowan Barker-Clarke, Jason Gray, Dagim Shiferaw Tadele, Michael Hinczewski, Jacob G Scott
Masking, maintenance and mimicry: the interplay of cell-intrinsic and cell-extrinsic effects in evolutionary games. bioRxiv : the preprint server for biology (2023)
Davis T Weaver, Jacob G Scott
Crosstalkr: An open-source R package to facilitate drug target identification. bioRxiv : the preprint server for biology (2023)
J Arvid Ågren, Jacob G Scott
Viruses, cancers, and evolutionary biology in the clinic: a commentary on Leeks et al. 2023. Journal of evolutionary biology 36 (11) (2023)
Eshan S King, Beck Pierce, Michael Hinczewski, Jacob G Scott
Diverse mutant selection windows shape spatial heterogeneity in evolving populations. bioRxiv : the preprint server for biology (2023)
Sara J Hamis, Panu Somervuo, J Arvid Ågren, Dagim Shiferaw Tadele, Juha Kesseli, Jacob G Scott, Matti Nykter, Philip Gerlee, Dmitri Finkelshtein, Otso Ovaskainen
Spatial cumulant models enable spatially informed treatment strategies and analysis of local interactions in cancer systems. Journal of mathematical biology 86 (5) (2023)
Davis T Weaver, Jeff A Maltas, Jacob G Scott
Reinforcement Learning informs optimal treatment strategies to limit antibiotic resistance. bioRxiv : the preprint server for biology (2023)
Dena Crozier, Jason Gray, Jeff A Maltas, Robert A Bonomo, Kyle J Card, Jacob G Scott
The evolution of diverse antimicrobial responses in vancomycin-intermediate Staphylococcus aureus and its therapeutic implications. bioRxiv : the preprint server for biology (2023)
Emily Ho, Loris De Cecco, Stefano Cavalieri, Geoffrey Sedor, Frank Hoebers, Ruud H Brakenhoff, Kathrin Scheckenbach, Tito Poli, Kailin Yang, Jessica A Scarborough, Shauna Campbell, Shlomo Koyfman, Steven A Eschrich, Jimmy J Caudell, Michael W Kattan, Lisa Licitra, Javier F Torres-Roca, Jacob G Scott
A clinicogenomic model including GARD predicts outcome for radiation treated patients with HPV+ oropharyngeal squamous cell carcinoma. medRxiv : the preprint server for health sciences (2023)
Eashwar Somasundaram, Raoul R Wadhwa, Adam Litzler, Rowan Barker-Clarke, Peng Qi, Gregory M M Videtic, Kevin Stephans, Nathan A Pennell, Daniel P Raymond, Kailin Yang, Michael W Kattan, Jacob G Scott
Clinical Nomogram Using Novel Computed Tomography-Based Radiomics Predicts Survival in Patients With Non-Small-Cell Lung Cancer Treated With Stereotactic Body Radiation Therapy. JCO clinical cancer informatics 7 (2023)
Vishhvaan Gopalakrishnan, Dena Crozier, Kyle J Card, Lacy D Chick, Nikhil P Krishnan, Erin McClure, Julia Pelesko, Drew F K Williamson, Daniel Nichol, Soumyajit Mandal, Robert A Bonomo, Jacob G Scott
A low-cost, open-source evolutionary bioreactor and its educational use. eLife 11 (2022)
Nathan Farrokhian, Jeff A Maltas, Mina N Dinh, Arda Durmaz, Patrick Ellsworth, Masahiro Hitomi, Erin McClure, Andriy Marusyk, Artem Kaznatcheev, Jacob G Scott
Measuring competitive exclusion in non-small cell lung cancer. Science advances 8 (26) (2022)
Davis T Weaver, Benjamin D McElvany, Vishhvaan Gopalakrishnan, Kyle J Card, Dena Crozier, Andrew Dhawan, Mina N Dinh, Emily Dolson, Nathan Farrokhian, Masahiro Hitomi, Emily Ho, Tanush Jagdish, Eshan S King, Jennifer L Cadnum, Curtis J Donskey, Nikhil Krishnan, Gleb Kuzmin, Ju Li, Jeff A Maltas, Jinhan Mo, Julia Pelesko, Jessica A Scarborough, Geoff Sedor, Enze Tian, Gary C An, Sean A Diehl, Jacob G Scott
UV decontamination of personal protective equipment with idle laboratory biosafety cabinets during the COVID-19 pandemic. PloS one 16 (7) (2021)
Davis T Weaver, Kathleen I Pishas, Drew F K Williamson, Jessica A Scarborough, Kirsten M Johnson, Andrew Dhawan, Jacob G Scott
Network potential identifies therapeutic miRNA cocktails in Ewing sarcoma. PLoS computational biology 17 (10) (2021)
Nara Yoon, Nikhil Krishnan, Jacob G Scott
Theoretical modeling of collaterally sensitive drug cycles: shaping heterogeneity to allow adaptive therapy. Journal of mathematical biology 83 (5) (2021)
Hassan Awada, Arda Durmaz, Carmelo Gurnari, Ashwin Kishtagari, Manja Meggendorfer, Cassandra M Kerr, Teodora Kuzmanovic, Jibran Durrani, Jacob Shreve, Yasunobu Nagata, Tomas Radivoyevitch, Anjali S Advani, Farhad Ravandi, Hetty E Carraway, Aziz Nazha, Claudia Haferlach, Yogen Saunthararajah, Jacob G Scott, Valeria Visconte, Hagop Kantarjian, Tapan Kadia, Mikkael A Sekeres, Torsten Haferlach, Jaroslaw P Maciejewski
Machine learning integrates genomic signatures for subclassification beyond primary and secondary acute myeloid leukemia. Blood 138 (19) (2021)
Nathaniel J Robinson, Masaru Miyagi, Jessica A Scarborough, Jacob G Scott, Derek J Taylor, William P Schiemann
SLX4IP promotes RAP1 SUMOylation by PIAS1 to coordinate telomere maintenance through NF-κB and Notch signaling. Science signaling 14 (689) (2021)
Andrew Dhawan, Jacob G Scott, Purnima Sundaresan, Michael Veness, Sandro Porceddu, Eric Hau, Adrian L Harris, Francesca M Buffa, Harriet E Gee
Role of gene signatures combined with pathology in classification of oropharynx head and neck cancer. Scientific reports 10 (1) (2020)
Robert Vander Velde, Nara Yoon, Viktoriya Marusyk, Arda Durmaz, Andrew Dhawan, Daria Miroshnychenko, Diego Lozano-Peral, Bina Desai, Olena Balynska, Jan Poleszhuk, Liu Kenian, Mingxiang Teng, Mohamed Abazeed, Omar Mian, Aik Choon Tan, Eric Haura, Jacob G Scott, Andriy Marusyk
Resistance to targeted therapies as a multifactorial, gradual adaptation to inhibitor specific selective pressures. Nature communications 11 (1) (2020)
Artem Kaznatcheev, Jeffrey Peacock, David Basanta, Andriy Marusyk, Jacob G Scott
Fibroblasts and alectinib switch the evolutionary games played by non-small cell lung cancer. Nature ecology & evolution 3 (3) (2019)
Daniel Nichol, Joseph Rutter, Christopher Bryant, Andrea M Hujer, Sai Lek, Mark D Adams, Peter Jeavons, Alexander R A Anderson, Robert A Bonomo, Jacob G Scott
Antibiotic collateral sensitivity is contingent on the repeatability of evolution. Nature communications 10 (1) (2019)
Andrew Dhawan, Alessandro Barberis, Wei-Chen Cheng, Enric Domingo, Catharine West, Tim Maughan, Jacob G Scott, Adrian L Harris, Francesca M Buffa
Guidelines for using sigQC for systematic evaluation of gene signatures. Nature protocols 14 (5) (2019)
Roberto Vargas, Priyanka Gopal, Gwendolyn B Kuzmishin, Robert DeBernardo, Shlomo A Koyfman, Babal K Jha, Omar Y Mian, Jacob G Scott, Drew J Adams, Craig D Peacock, Mohamed E Abazeed
Case study: patient-derived clear cell adenocarcinoma xenograft model longitudinally predicts treatment response. NPJ precision oncology 2 (2018)
Andrew Dhawan, Jacob G Scott, Adrian L Harris, Francesca M Buffa
Pan-cancer characterisation of microRNA across cancer hallmarks reveals microRNA-mediated downregulation of tumour suppressors. Nature communications 9 (1) (2018)
M Zhou, Jacob G Scott, B Chaudhury, Lawrence O Hall, Dmitry B Goldgof, Kristen W Yeom, Michael Iv, Yangming Ou, Jayashree Kalpathy-Cramer, Sandy Napel, Robert James Gillies, Olivier Gevaert, Robert A Gatenby
Radiomics in Brain Tumor: Image Assessment, Quantitative Feature Descriptors, and Machine-Learning Approaches. AJNR. American journal of neuroradiology 39 (2) (2017)
Bertrand Ottino-Loffler, Jacob G Scott, Steven H Strogatz
Evolutionary dynamics of incubation periods. eLife 6 (2017)

Jacob G Scott.css-eqlu8i{font-size:small;padding-left:4px;} (Jacob Scott, J Scott)

Publication Activity (10 Years)

Top Topics

Top Venues

Jacob G Scott (Jacob Scott, J Scott)