Robert A Bonomo (R A Bonomo)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 163

Top Venues

Antimicrobial agents and chemotherapy

mBio

Journal of chemical information and modeling

ACS infectious diseases

This page only lists publications with an associated author ORCID identifier.

Publications

Yu Zhu, Jing Gu, Zhuoran Zhao, Ah Wing Edith Chan, Maria F Mojica, Andrea M Hujer, Robert A Bonomo, Shozeb M Haider
Deciphering the Coevolutionary Dynamics of L2 β-Lactamases via Deep Learning. Journal of chemical information and modeling 64 (9) (2024)
Alina Iovleva, Christi L McElheny, Erin L Fowler, Eric Cober, Erica S Herc, César A Arias, Carol Hill, Keri Baum, Vance G Fowler, Henry F Chambers, Kerryl E Greenwood-Quaintance, Robin Patel, David Van Duin, Robert A Bonomo, Yohei Doi
In vitro activity of sulbactam-durlobactam against colistin-resistant and/or cefiderocol-non-susceptible, carbapenem-resistant Acinetobacter baumannii collected in U.S. hospitals. Antimicrobial agents and chemotherapy 68 (3) (2024)
Dariusz A Hareza, Sara E Cosgrove, Robert A Bonomo, Kathryn Dzintars, Sara M Karaba, Armani M Hawes, Tsigereda Tekle, Patricia J Simner, Pranita D Tamma
Clinical outcomes and emergence of resistance of Pseudomonas aeruginosa infections treated with ceftolozane-tazobactam versus ceftazidime-avibactam. Antimicrobial agents and chemotherapy (2024)
Elsa De la Cadena, María Fernanda Mojica, Laura J Rojas, Betsy E Castro, Juan Carlos García-Betancur, Steven H Marshall, Natalia Restrepo, Nancy Patricia Castro-Caro, Magalis Fonseca-Carrillo, Christian Pallares, Robert A Bonomo, María Virginia Villegas
First report of KPC variants conferring ceftazidime-avibactam resistance in Colombia: introducing KPC-197. Microbiology spectrum 12 (6) (2024)
Daisuke Ono, María Fernanda Mojica, Christopher R Bethel, Yoshikazu Ishii, Salvador I Drusin, Diego Martín Moreno, Alejandro J Vila, Robert A Bonomo
Structural role of K224 in taniborbactam inhibition of NDM-1. Antimicrobial agents and chemotherapy 68 (2) (2024)
Yuanyuan Jiao, Jun Yan, Dhruvitkumar S Sutaria, Peggy Lu, Michael Vicchiarelli, Zeferino Reyna, Juan Ruiz-Delgado, Elizabeth Burk, Eugene Moon, Nirav R Shah, Brad Spellberg, Robert A Bonomo, George L Drusano, Arnold Louie, Brian M Luna, Juergen B Bulitta
Population pharmacokinetics and humanized dosage regimens matching the peak, area, trough, and range of amikacin plasma concentrations in immune-competent murine bloodstream and lung infection models. Antimicrobial agents and chemotherapy 68 (3) (2024)
Zishuo Cheng, Mahesh Aitha, Caitlyn A Thomas, Aidan Sturgill, Mitch Fairweather, Amy Hu, Christopher R Bethel, Dann D Rivera, Patricia Dranchak, Pei W Thomas, Han Li, Qi Feng, Kaicheng Tao, Minshuai Song, Na Sun, Shuo Wang, Surendra Bikram Silwal, Richard C Page, Walter Fast, Robert A Bonomo, Maria Weese, Waldyn Martinez, James Inglese, Michael W Crowder
Machine Learning Models Identify Inhibitors of New Delhi Metallo-β-lactamase. Journal of chemical information and modeling 64 (10) (2024)
Alina Iovleva, Christi L McElheny, Erin L Fowler, Eric Cober, Erica S Herc, César A Arias, Carol Hill, Keri Baum, Vance G Fowler, Henry F Chambers, Kerryl E Greenwood-Quaintance, Robin Patel, David Van Duin, Robert A Bonomo, Yohei Doi
In vitro activity of sulbactam-durlobactam against colistin-resistant and/or cefiderocol-non-susceptible, carbapenem-resistant Acinetobacter baumannii collected in U.S. hospitals. Antimicrobial agents and chemotherapy 68 (3) (2024)
Zishuo Cheng, Mahesh Aitha, Caitlyn A Thomas, Aidan Sturgill, Mitch Fairweather, Amy Hu, Christopher R Bethel, Dann D Rivera, Patricia Dranchak, Pei W Thomas, Han Li, Qi Feng, Kaicheng Tao, Minshuai Song, Na Sun, Shuo Wang, Surendra Bikram Silwal, Richard C Page, Walter Fast, Robert A Bonomo, Maria Weese, Waldyn Martinez, James Inglese, Michael W Crowder
Machine Learning Models Identify Inhibitors of New Delhi Metallo-β-lactamase. Journal of chemical information and modeling 64 (10) (2024)
Leila S Hojat, Brigid M Wilson, Michael J Satlin, Federico Perez, María Fernanda Mojica, Mendel E Singer, Robert A Bonomo, Lauren H Epstein
14-Year Epidemiologic study of Pseudomonas aeruginosa bloodstream infection incidence and resistance in the Veterans Health Administration system, 2009-2022. JAC-antimicrobial resistance 6 (2) (2024)
Yuanyuan Jiao, Jun Yan, Dhruvitkumar S Sutaria, Peggy Lu, Michael Vicchiarelli, Zeferino Reyna, Juan Ruiz-Delgado, Elizabeth Burk, Eugene Moon, Nirav R Shah, Brad Spellberg, Robert A Bonomo, George L Drusano, Arnold Louie, Brian M Luna, Juergen B Bulitta
Population pharmacokinetics and humanized dosage regimens matching the peak, area, trough, and range of amikacin plasma concentrations in immune-competent murine bloodstream and lung infection models. Antimicrobial agents and chemotherapy (2024)
Elsa De la Cadena, María Fernanda Mojica, Laura J Rojas, Betsy E Castro, Juan Carlos García-Betancur, Steven H Marshall, Natalia Restrepo, Nancy Patricia Castro-Caro, Magalis Fonseca-Carrillo, Christian Pallares, Robert A Bonomo, María Virginia Villegas
First report of KPC variants conferring ceftazidime-avibactam resistance in Colombia: introducing KPC-197. Microbiology spectrum (2024)
Lilian M Abbo, Kailynn DeRonde, Adriana Jimenez, Michael Piazza, Christine Vu, Octavio Martinez, Laura J Rojas, Steven Marshall, Mohamad Yasmin, Robert A Bonomo, Lilian M Abbo
Difficult-to-treat (DTR) Pseudomonas aeruginosa harboring Verona-Integron metallo-β-lactamase ( bla VIM ): infection management and molecular analysis. Antimicrobial agents and chemotherapy 68 (5) (2024)
Olivia Wong, Vyanka Mezcord, Christina Lopez, German Matias Traglia, Fernando Pasteran, Marisel R Tuttobene, Alejandra Corso, Marcelo E Tolmasky, Robert A Bonomo, Maria Soledad Ramirez
Hetero-antagonism of avibactam and sulbactam with cefiderocol in carbapenem-resistant Acinetobacter spp. Microbiology spectrum (2024)
Zishuo Cheng, Mahesh Aitha, Caitlyn A Thomas, Aidan Sturgill, Mitch Fairweather, Amy Hu, Christopher R Bethel, Dann D Rivera, Patricia Dranchak, Pei W Thomas, Han Li, Qi Feng, Kaicheng Tao, Minshuai Song, Na Sun, Shuo Wang, Surendra Bikram Silwal, Richard C Page, Walter Fast, Robert A Bonomo, Maria Weese, Waldyn Martinez, James Inglese, Michael W Crowder
Machine Learning Models Identify Inhibitors of New Delhi Metallo-β-lactamase. Journal of chemical information and modeling (2024)
Valentina Villamil, Maria-Agustina Rossi, Maria F Mojica, Philip Hinchliffe, Verónica Martínez, Valerie Castillo, Cecilia Saiz, Claudia Banchio, Mario A Macías, James Spencer, Robert A Bonomo, Alejandro Vila, Diego Martín Moreno, Graciela Mahler
Rational Design of Benzobisheterocycle Metallo-β-Lactamase Inhibitors: A Tricyclic Scaffold Enhances Potency against Target Enzymes. Journal of medicinal chemistry (2024)
Lilian M Abbo, Kailynn DeRonde, Adriana Jimenez, Michael Piazza, Christine Vu, Octavio Martinez, Laura J Rojas, Steven Marshall, Mohamad Yasmin, Robert A Bonomo, Lilian M Abbo
Difficult-to-treat (DTR) Pseudomonas aeruginosa harboring Verona-Integron metallo-β-lactamase ( bla VIM ): infection management and molecular analysis. Antimicrobial agents and chemotherapy (2024)
Yu Zhu, Jing Gu, Zhuoran Zhao, Ah Wing Edith Chan, Maria F Mojica, Andrea M Hujer, Robert A Bonomo, Shozeb M Haider
Deciphering the Coevolutionary Dynamics of L2 β-Lactamases via Deep Learning. Journal of chemical information and modeling 64 (9) (2024)
Bradford Becken, Khalid M Dousa, John L Johnson, Steven M Holland, Robert A Bonomo
Dual β-lactam for treatment of pulmonary Mycobacterium abscessus in a child. Antimicrobial agents and chemotherapy (2024)
Alina Iovleva, Christi L McElheny, Erin L Fowler, Eric Cober, Erica S Herc, César A Arias, Carol Hill, Keri Baum, Vance G Fowler, Henry F Chambers, Kerryl E Greenwood-Quaintance, Robin Patel, David Van Duin, Robert A Bonomo, Yohei Doi
In vitro activity of sulbactam-durlobactam against colistin-resistant and/or cefiderocol-non-susceptible, carbapenem-resistant Acinetobacter baumannii collected in U.S. hospitals. Antimicrobial agents and chemotherapy (2024)
Valentina Villamil, Maria-Agustina Rossi, Maria F Mojica, Philip Hinchliffe, Verónica Martínez, Valerie Castillo, Cecilia Saiz, Claudia Banchio, Mario A Macías, James Spencer, Robert A Bonomo, Alejandro Vila, Diego Martín Moreno, Graciela Mahler
Rational Design of Benzobisheterocycle Metallo-β-Lactamase Inhibitors: A Tricyclic Scaffold Enhances Potency against Target Enzymes. Journal of medicinal chemistry 67 (5) (2024)
Khalid M Dousa, Eunjeong Shin, Sebastian G Kurz, Mark Plummer, Mary Nantongo, Christopher R Bethel, David C Nguyen, Barry N Kreiswith, Charles L Daley, Kenneth E Remy, Steven M Holland, Robert A Bonomo
Synergistic effects of sulopenem in combination with cefuroxime or durlobactam against Mycobacterium abscessus . mBio 15 (6) (2024)
Daisuke Ono, Anna Cmolik, Christopher R Bethel, Yoshikazu Ishii, Salvador Iván Drusin, Diego Martín Moreno, Alejandro J Vila, Robert A Bonomo, María Fernanda Mojica
The interaction of the azetidine thiazole side chain with the active site loop (ASL) 3 drives the evolution of IMP metallo-β-lactamase against tebipenem. Antimicrobial agents and chemotherapy (2024)
Mary Nantongo, David C Nguyen, Christopher R Bethel, Magdalena A Taracila, Qing Li, Khalid M Dousa, Eunjeong Shin, Sebastian G Kurz, Liem Nguyen, Barry N Kreiswirth, W Henry Boom, Mark S Plummer, Robert A Bonomo
Durlobactam, a Diazabicyclooctane β-Lactamase Inhibitor, Inhibits BlaC and Peptidoglycan Transpeptidases of Mycobacterium tuberculosis . ACS infectious diseases (2024)
Elsa De la Cadena, María Fernanda Mojica, Laura J Rojas, Betsy E Castro, Juan Carlos García-Betancur, Steven H Marshall, Natalia Restrepo, Nancy Patricia Castro-Caro, Magalis Fonseca-Carrillo, Christian Pallares, Robert A Bonomo, María Virginia Villegas
First report of KPC variants conferring ceftazidime-avibactam resistance in Colombia: introducing KPC-197. Microbiology spectrum 12 (6) (2024)
Jieqiang Zhou, Yuli Qian, Yinzhi Lang, Yongzhen Zhang, Xun Tao, Bartolome Moya, Alaa R M Sayed, Cornelia B Landersdorfer, Eunjeong Shin, Carolin Werkman, Nicholas M Smith, Tae Hwan Kim, Monika Kumaraswamy, Beom Soo Shin, Brian T Tsuji, Robert A Bonomo, Richard E Lee, Juergen B Bulitta
Comprehensive stability analysis of 13 β-lactams and β-lactamase inhibitors in in vitro media, and novel supplement dosing strategy to mitigate thermal drug degradation. Antimicrobial agents and chemotherapy (2024)
Daisuke Ono, Anna Cmolik, Christopher R Bethel, Yoshikazu Ishii, Salvador Iván Drusin, Diego Martín Moreno, Alejandro J Vila, Robert A Bonomo, María Fernanda Mojica
The interaction of the azetidine thiazole side chain with the active site loop (ASL) 3 drives the evolution of IMP metallo-β-lactamase against tebipenem. Antimicrobial agents and chemotherapy 68 (8) (2024)
Mohamad Yasmin, Steven H Marshall, Liang Chen, Daniel D Rhoads, Michael R Jacobs, Laura J Rojas, Federico Perez, Andrea M Hujer, Kristine M Hujer, David Van Duin, Vance Fowler, Henry F Chambers, Barry N Kreiswirth, Robert A Bonomo, null null
A molecular analysis of meropenem-vaborbactam non-susceptible KPC-producing Klebsiella pneumoniae . Antimicrobial agents and chemotherapy (2024)
Olivia Wong, Vyanka Mezcord, Christina Lopez, German Matias Traglia, Fernando Pasteran, Marisel R Tuttobene, Alejandra Corso, Marcelo E Tolmasky, Robert A Bonomo, Maria Soledad Ramirez
Hetero-antagonism of avibactam and sulbactam with cefiderocol in carbapenem-resistant Acinetobacter spp. bioRxiv : the preprint server for biology (2024)
Leila S Hojat, Brigid M Wilson, Michael J Satlin, Federico Perez, María Fernanda Mojica, Mendel E Singer, Robert A Bonomo, Lauren H Epstein
14-Year Epidemiologic study of Pseudomonas aeruginosa bloodstream infection incidence and resistance in the Veterans Health Administration system, 2009-2022. JAC-antimicrobial resistance 6 (2) (2024)
Alina Iovleva, Christi L McElheny, Erin L Fowler, Eric Cober, Erica S Herc, César A Arias, Carol Hill, Keri Baum, Vance G Fowler, Henry F Chambers, Kerryl E Greenwood-Quaintance, Robin Patel, David Van Duin, Robert A Bonomo, Yohei Doi
In vitro activity of sulbactam-durlobactam against colistin-resistant and/or cefiderocol-non-susceptible, carbapenem-resistant Acinetobacter baumannii collected in U.S. hospitals. Antimicrobial agents and chemotherapy 68 (3) (2024)
Zishuo Cheng, Mahesh Aitha, Caitlyn A Thomas, Aidan Sturgill, Mitch Fairweather, Amy Hu, Christopher R Bethel, Dann D Rivera, Patricia Dranchak, Pei W Thomas, Han Li, Qi Feng, Kaicheng Tao, Minshuai Song, Na Sun, Shuo Wang, Surendra Bikram Silwal, Richard C Page, Walter Fast, Robert A Bonomo, Maria Weese, Waldyn Martinez, James Inglese, Michael W Crowder
Machine Learning Models Identify Inhibitors of New Delhi Metallo-β-lactamase. Journal of chemical information and modeling 64 (10) (2024)
Yuanyuan Jiao, Jun Yan, Dhruvitkumar S Sutaria, Peggy Lu, Michael Vicchiarelli, Zeferino Reyna, Juan Ruiz-Delgado, Elizabeth Burk, Eugene Moon, Nirav R Shah, Brad Spellberg, Robert A Bonomo, George L Drusano, Arnold Louie, Brian M Luna, Juergen B Bulitta
Population pharmacokinetics and humanized dosage regimens matching the peak, area, trough, and range of amikacin plasma concentrations in immune-competent murine bloodstream and lung infection models. Antimicrobial agents and chemotherapy 68 (3) (2024)
Jieqiang Zhou, Yuli Qian, Yinzhi Lang, Yongzhen Zhang, Xun Tao, Bartolome Moya, Alaa R M Sayed, Cornelia B Landersdorfer, Eunjeong Shin, Carolin Werkman, Nicholas M Smith, Tae Hwan Kim, Monika Kumaraswamy, Beom Soo Shin, Brian T Tsuji, Robert A Bonomo, Richard E Lee, Juergen B Bulitta
Comprehensive stability analysis of 13 β-lactams and β-lactamase inhibitors in in vitro media, and novel supplement dosing strategy to mitigate thermal drug degradation. Antimicrobial agents and chemotherapy 68 (3) (2024)
Olivia Wong, Vyanka Mezcord, Christina Lopez, German Matias Traglia, Fernando Pasteran, Marisel R Tuttobene, Alejandra Corso, Marcelo E Tolmasky, Robert A Bonomo, Maria Soledad Ramirez
Hetero-antagonism of avibactam and sulbactam with cefiderocol in carbapenem-resistant Acinetobacter spp. bioRxiv : the preprint server for biology (2024)
Khalid M Dousa, Eunjeong Shin, Sebastian G Kurz, Mark Plummer, Mary Nantongo, Christopher R Bethel, David C Nguyen, Barry N Kreiswith, Charles L Daley, Kenneth E Remy, Steven M Holland, Robert A Bonomo
Synergistic effects of sulopenem in combination with cefuroxime or durlobactam against Mycobacterium abscessus . mBio (2024)
Khalid M Dousa, Eunjeong Shin, Sebastian G Kurz, Mark Plummer, Mary Nantongo, Christopher R Bethel, David C Nguyen, Barry N Kreiswith, Charles L Daley, Kenneth E Remy, Steven M Holland, Robert A Bonomo
Synergistic effects of sulopenem in combination with cefuroxime or durlobactam against Mycobacterium abscessus . mBio 15 (6) (2024)
Daisuke Ono, Anna Cmolik, Christopher R Bethel, Yoshikazu Ishii, Salvador Iván Drusin, Diego Martín Moreno, Alejandro J Vila, Robert A Bonomo, María Fernanda Mojica
The interaction of the azetidine thiazole side chain with the active site loop (ASL) 3 drives the evolution of IMP metallo-β-lactamase against tebipenem. Antimicrobial agents and chemotherapy 68 (8) (2024)
Daisuke Ono, María Fernanda Mojica, Christopher R Bethel, Yoshikazu Ishii, Salvador I Drusin, Diego Martín Moreno, Alejandro J Vila, Robert A Bonomo
Structural role of K224 in taniborbactam inhibition of NDM-1. Antimicrobial agents and chemotherapy 68 (2) (2024)
Olivia Wong, Vyanka Mezcord, Christina Lopez, German Matias Traglia, Fernando Pasteran, Marisel R Tuttobene, Alejandra Corso, Marcelo E Tolmasky, Robert A Bonomo, Maria Soledad Ramirez
Hetero-antagonism of avibactam and sulbactam with cefiderocol in carbapenem-resistant Acinetobacter spp. Microbiology spectrum (2024)
Yuanyuan Jiao, Jun Yan, Dhruvitkumar S Sutaria, Peggy Lu, Michael Vicchiarelli, Zeferino Reyna, Juan Ruiz-Delgado, Elizabeth Burk, Eugene Moon, Nirav R Shah, Brad Spellberg, Robert A Bonomo, George L Drusano, Arnold Louie, Brian M Luna, Juergen B Bulitta
Population pharmacokinetics and humanized dosage regimens matching the peak, area, trough, and range of amikacin plasma concentrations in immune-competent murine bloodstream and lung infection models. Antimicrobial agents and chemotherapy 68 (3) (2024)
Jieqiang Zhou, Yuli Qian, Yinzhi Lang, Yongzhen Zhang, Xun Tao, Bartolome Moya, Alaa R M Sayed, Cornelia B Landersdorfer, Eunjeong Shin, Carolin Werkman, Nicholas M Smith, Tae Hwan Kim, Monika Kumaraswamy, Beom Soo Shin, Brian T Tsuji, Robert A Bonomo, Richard E Lee, Juergen B Bulitta
Comprehensive stability analysis of 13 β-lactams and β-lactamase inhibitors in in vitro media, and novel supplement dosing strategy to mitigate thermal drug degradation. Antimicrobial agents and chemotherapy 68 (3) (2024)
Alina Iovleva, Christi L McElheny, Erin L Fowler, Eric Cober, Erica S Herc, César A Arias, Carol Hill, Keri Baum, Vance G Fowler, Henry F Chambers, Kerryl E Greenwood-Quaintance, Robin Patel, David Van Duin, Robert A Bonomo, Yohei Doi
In vitro activity of sulbactam-durlobactam against colistin-resistant and/or cefiderocol-non-susceptible, carbapenem-resistant Acinetobacter baumannii collected in U.S. hospitals. Antimicrobial agents and chemotherapy 68 (3) (2024)
Lilian M Abbo, Kailynn DeRonde, Adriana Jimenez, Michael Piazza, Christine Vu, Octavio Martinez, Laura J Rojas, Steven Marshall, Mohamad Yasmin, Robert A Bonomo, Lilian M Abbo
Difficult-to-treat (DTR) Pseudomonas aeruginosa harboring Verona-Integron metallo-β-lactamase ( bla VIM ): infection management and molecular analysis. Antimicrobial agents and chemotherapy 68 (5) (2024)
Leila S Hojat, Brigid M Wilson, Michael J Satlin, Federico Perez, María Fernanda Mojica, Mendel E Singer, Robert A Bonomo, Lauren H Epstein
14-Year Epidemiologic study of Pseudomonas aeruginosa bloodstream infection incidence and resistance in the Veterans Health Administration system, 2009-2022. JAC-antimicrobial resistance 6 (2) (2024)
Zishuo Cheng, Mahesh Aitha, Caitlyn A Thomas, Aidan Sturgill, Mitch Fairweather, Amy Hu, Christopher R Bethel, Dann D Rivera, Patricia Dranchak, Pei W Thomas, Han Li, Qi Feng, Kaicheng Tao, Minshuai Song, Na Sun, Shuo Wang, Surendra Bikram Silwal, Richard C Page, Walter Fast, Robert A Bonomo, Maria Weese, Waldyn Martinez, James Inglese, Michael W Crowder
Machine Learning Models Identify Inhibitors of New Delhi Metallo-β-lactamase. Journal of chemical information and modeling 64 (10) (2024)
Mary Nantongo, David C Nguyen, Christopher R Bethel, Magdalena A Taracila, Qing Li, Khalid M Dousa, Eunjeong Shin, Sebastian G Kurz, Liem Nguyen, Barry N Kreiswirth, W Henry Boom, Mark S Plummer, Robert A Bonomo
Durlobactam, a Diazabicyclooctane β-Lactamase Inhibitor, Inhibits BlaC and Peptidoglycan Transpeptidases of Mycobacterium tuberculosis . ACS infectious diseases (2024)
Khalid M Dousa, Eunjeong Shin, Sebastian G Kurz, Mark Plummer, Mary Nantongo, Christopher R Bethel, David C Nguyen, Barry N Kreiswith, Charles L Daley, Kenneth E Remy, Steven M Holland, Robert A Bonomo
Synergistic effects of sulopenem in combination with cefuroxime or durlobactam against Mycobacterium abscessus . mBio 15 (6) (2024)
Alina Iovleva, Christi L McElheny, Erin L Fowler, Eric Cober, Erica S Herc, César A Arias, Carol Hill, Keri Baum, Vance G Fowler, Henry F Chambers, Kerryl E Greenwood-Quaintance, Robin Patel, David Van Duin, Robert A Bonomo, Yohei Doi
In vitro activity of sulbactam-durlobactam against colistin-resistant and/or cefiderocol-non-susceptible, carbapenem-resistant Acinetobacter baumannii collected in U.S. hospitals. Antimicrobial agents and chemotherapy 68 (3) (2024)
Yuanyuan Jiao, Jun Yan, Dhruvitkumar S Sutaria, Peggy Lu, Michael Vicchiarelli, Zeferino Reyna, Juan Ruiz-Delgado, Elizabeth Burk, Eugene Moon, Nirav R Shah, Brad Spellberg, Robert A Bonomo, George L Drusano, Arnold Louie, Brian M Luna, Juergen B Bulitta
Population pharmacokinetics and humanized dosage regimens matching the peak, area, trough, and range of amikacin plasma concentrations in immune-competent murine bloodstream and lung infection models. Antimicrobial agents and chemotherapy 68 (3) (2024)
Zishuo Cheng, Mahesh Aitha, Caitlyn A Thomas, Aidan Sturgill, Mitch Fairweather, Amy Hu, Christopher R Bethel, Dann D Rivera, Patricia Dranchak, Pei W Thomas, Han Li, Qi Feng, Kaicheng Tao, Minshuai Song, Na Sun, Shuo Wang, Surendra Bikram Silwal, Richard C Page, Walter Fast, Robert A Bonomo, Maria Weese, Waldyn Martinez, James Inglese, Michael W Crowder
Machine Learning Models Identify Inhibitors of New Delhi Metallo-β-lactamase. Journal of chemical information and modeling (2024)
Daisuke Ono, María Fernanda Mojica, Christopher R Bethel, Yoshikazu Ishii, Salvador I Drusin, Diego Martín Moreno, Alejandro J Vila, Robert A Bonomo
Structural role of K224 in taniborbactam inhibition of NDM-1. Antimicrobial agents and chemotherapy 68 (2) (2024)
Melina Ruggiero, Ivan Briceño Muñoz, Gabriel Gutkind, Andrea M Hujer, Robert A Bonomo, Pablo Power
Insights into the activity of cefiderocol against PER-2 producing Enterobacterales. Antimicrobial agents and chemotherapy (2024)
Daisuke Ono, Anna Cmolik, Christopher R Bethel, Yoshikazu Ishii, Salvador Iván Drusin, Diego Martín Moreno, Alejandro J Vila, Robert A Bonomo, María Fernanda Mojica
The interaction of the azetidine thiazole side chain with the active site loop (ASL) 3 drives the evolution of IMP metallo-β-lactamase against tebipenem. Antimicrobial agents and chemotherapy 68 (8) (2024)
Elsa De la Cadena, María Fernanda Mojica, Laura J Rojas, Betsy E Castro, Juan Carlos García-Betancur, Steven H Marshall, Natalia Restrepo, Nancy Patricia Castro-Caro, Magalis Fonseca-Carrillo, Christian Pallares, Robert A Bonomo, María Virginia Villegas
First report of KPC variants conferring ceftazidime-avibactam resistance in Colombia: introducing KPC-197. Microbiology spectrum 12 (6) (2024)
Lilian M Abbo, Kailynn DeRonde, Adriana Jimenez, Michael Piazza, Christine Vu, Octavio Martinez, Laura J Rojas, Steven Marshall, Mohamad Yasmin, Robert A Bonomo, Lilian M Abbo
Difficult-to-treat (DTR) Pseudomonas aeruginosa harboring Verona-Integron metallo-β-lactamase ( bla VIM ): infection management and molecular analysis. Antimicrobial agents and chemotherapy 68 (5) (2024)
Bradford Becken, Khalid M Dousa, John L Johnson, Steven M Holland, Robert A Bonomo
Dual β-lactam for treatment of pulmonary Mycobacterium abscessus in a child. Antimicrobial agents and chemotherapy 68 (7) (2024)
Alina Iovleva, Christi L McElheny, Erin L Fowler, Eric Cober, Erica S Herc, César A Arias, Carol Hill, Keri Baum, Vance G Fowler, Henry F Chambers, Kerryl E Greenwood-Quaintance, Robin Patel, David Van Duin, Robert A Bonomo, Yohei Doi
In vitro activity of sulbactam-durlobactam against colistin-resistant and/or cefiderocol-non-susceptible, carbapenem-resistant Acinetobacter baumannii collected in U.S. hospitals. Antimicrobial agents and chemotherapy 68 (3) (2024)
Yuanyuan Jiao, Jun Yan, Dhruvitkumar S Sutaria, Peggy Lu, Michael Vicchiarelli, Zeferino Reyna, Juan Ruiz-Delgado, Elizabeth Burk, Eugene Moon, Nirav R Shah, Brad Spellberg, Robert A Bonomo, George L Drusano, Arnold Louie, Brian M Luna, Juergen B Bulitta
Population pharmacokinetics and humanized dosage regimens matching the peak, area, trough, and range of amikacin plasma concentrations in immune-competent murine bloodstream and lung infection models. Antimicrobial agents and chemotherapy 68 (3) (2024)
Yuanyuan Jiao, Jun Yan, Dhruvitkumar S Sutaria, Peggy Lu, Michael Vicchiarelli, Zeferino Reyna, Juan Ruiz-Delgado, Elizabeth Burk, Eugene Moon, Nirav R Shah, Brad Spellberg, Robert A Bonomo, George L Drusano, Arnold Louie, Brian M Luna, Juergen B Bulitta
Population pharmacokinetics and humanized dosage regimens matching the peak, area, trough, and range of amikacin plasma concentrations in immune-competent murine bloodstream and lung infection models. Antimicrobial agents and chemotherapy 68 (3) (2024)
Bradford Becken, Khalid M Dousa, John L Johnson, Steven M Holland, Robert A Bonomo
Dual β-lactam for treatment of pulmonary Mycobacterium abscessus in a child. Antimicrobial agents and chemotherapy 68 (7) (2024)
Alina Iovleva, Christi L McElheny, Erin L Fowler, Eric Cober, Erica S Herc, César A Arias, Carol Hill, Keri Baum, Vance G Fowler, Henry F Chambers, Kerryl E Greenwood-Quaintance, Robin Patel, David Van Duin, Robert A Bonomo, Yohei Doi
In vitro activity of sulbactam-durlobactam against colistin-resistant and/or cefiderocol-non-susceptible, carbapenem-resistant Acinetobacter baumannii collected in U.S. hospitals. Antimicrobial agents and chemotherapy 68 (3) (2024)
Barbara Ghiglione, María Margarita Rodríguez, Pedro Penzotti, Christopher R Bethel, Gabriel Gutkind, Robert A Bonomo, Sebastián Klinke, Pablo Power
Crystal structure of the class A extended-spectrum β-lactamase CTX-M-96 in complex with relebactam at 1.03 Angstrom resolution. Antimicrobial agents and chemotherapy 68 (8) (2024)
Daisuke Ono, María Fernanda Mojica, Christopher R Bethel, Yoshikazu Ishii, Salvador I Drusin, Diego Martín Moreno, Alejandro J Vila, Robert A Bonomo
Structural role of K224 in taniborbactam inhibition of NDM-1. Antimicrobial agents and chemotherapy 68 (2) (2024)
Jieqiang Zhou, Yuli Qian, Yinzhi Lang, Yongzhen Zhang, Xun Tao, Bartolome Moya, Alaa R M Sayed, Cornelia B Landersdorfer, Eunjeong Shin, Carolin Werkman, Nicholas M Smith, Tae Hwan Kim, Monika Kumaraswamy, Beom Soo Shin, Brian T Tsuji, Robert A Bonomo, Richard E Lee, Juergen B Bulitta
Comprehensive stability analysis of 13 β-lactams and β-lactamase inhibitors in in vitro media, and novel supplement dosing strategy to mitigate thermal drug degradation. Antimicrobial agents and chemotherapy 68 (3) (2024)
Yu Zhu, Jing Gu, Zhuoran Zhao, Ah Wing Edith Chan, Maria F Mojica, Andrea M Hujer, Robert A Bonomo, Shozeb M Haider
Deciphering the Coevolutionary Dynamics of L2 β-Lactamases via Deep Learning. Journal of chemical information and modeling 64 (9) (2024)
Michael R Jacobs, Ayman M Abdelhamed, Caryn E Good, Andrew R Mack, Christopher R Bethel, Steven Marshall, Andrea M Hujer, Kristine M Hujer, Robin Patel, David Van Duin, Vance G Fowler, Daniel D Rhoads, David A Six, Greg Moeck, Tsuyoshi Uehara, Krisztina M Papp-Wallace, Robert A Bonomo
ARGONAUT-III and -V: susceptibility of carbapenem-resistant Klebsiella pneumoniae and multidrug-resistant Pseudomonas aeruginosa to the bicyclic boronate β-lactamase inhibitor taniborbactam combined with cefepime. Antimicrobial agents and chemotherapy (2024)
Jieqiang Zhou, Yuli Qian, Yinzhi Lang, Yongzhen Zhang, Xun Tao, Bartolome Moya, Alaa R M Sayed, Cornelia B Landersdorfer, Eunjeong Shin, Carolin Werkman, Nicholas M Smith, Tae Hwan Kim, Monika Kumaraswamy, Beom Soo Shin, Brian T Tsuji, Robert A Bonomo, Richard E Lee, Juergen B Bulitta
Comprehensive stability analysis of 13 β-lactams and β-lactamase inhibitors in in vitro media, and novel supplement dosing strategy to mitigate thermal drug degradation. Antimicrobial agents and chemotherapy 68 (3) (2024)
Daisuke Ono, María Fernanda Mojica, Christopher R Bethel, Yoshikazu Ishii, Salvador I Drusin, Diego Martín Moreno, Alejandro J Vila, Robert A Bonomo
Structural role of K224 in taniborbactam inhibition of NDM-1. Antimicrobial agents and chemotherapy 68 (2) (2024)
Jieqiang Zhou, Yuli Qian, Yinzhi Lang, Yongzhen Zhang, Xun Tao, Bartolome Moya, Alaa R M Sayed, Cornelia B Landersdorfer, Eunjeong Shin, Carolin Werkman, Nicholas M Smith, Tae Hwan Kim, Monika Kumaraswamy, Beom Soo Shin, Brian T Tsuji, Robert A Bonomo, Richard E Lee, Juergen B Bulitta
Comprehensive stability analysis of 13 β-lactams and β-lactamase inhibitors in in vitro media, and novel supplement dosing strategy to mitigate thermal drug degradation. Antimicrobial agents and chemotherapy 68 (3) (2024)
Alina Iovleva, Christi L McElheny, Erin L Fowler, Eric Cober, Erica S Herc, César A Arias, Carol Hill, Keri Baum, Vance G Fowler, Henry F Chambers, Kerryl E Greenwood-Quaintance, Robin Patel, David Van Duin, Robert A Bonomo, Yohei Doi
In vitro activity of sulbactam-durlobactam against colistin-resistant and/or cefiderocol-non-susceptible, carbapenem-resistant Acinetobacter baumannii collected in U.S. hospitals. Antimicrobial agents and chemotherapy 68 (3) (2024)
Lilian M Abbo, Kailynn DeRonde, Adriana Jimenez, Michael Piazza, Christine Vu, Octavio Martinez, Laura J Rojas, Steven Marshall, Mohamad Yasmin, Robert A Bonomo, Lilian M Abbo
Difficult-to-treat (DTR) Pseudomonas aeruginosa harboring Verona-Integron metallo-β-lactamase ( bla VIM ): infection management and molecular analysis. Antimicrobial agents and chemotherapy 68 (5) (2024)
Olivia Wong, Vyanka Mezcord, Christina Lopez, German Matias Traglia, Fernando Pasteran, Marisel R Tuttobene, Alejandra Corso, Marcelo E Tolmasky, Robert A Bonomo, Maria Soledad Ramirez
Hetero-antagonism of avibactam and sulbactam with cefiderocol in carbapenem-resistant Acinetobacter spp. bioRxiv : the preprint server for biology (2024)
Zishuo Cheng, Mahesh Aitha, Caitlyn A Thomas, Aidan Sturgill, Mitch Fairweather, Amy Hu, Christopher R Bethel, Dann D Rivera, Patricia Dranchak, Pei W Thomas, Han Li, Qi Feng, Kaicheng Tao, Minshuai Song, Na Sun, Shuo Wang, Surendra Bikram Silwal, Richard C Page, Walter Fast, Robert A Bonomo, Maria Weese, Waldyn Martinez, James Inglese, Michael W Crowder
Machine Learning Models Identify Inhibitors of New Delhi Metallo-β-lactamase. Journal of chemical information and modeling (2024)
Jieqiang Zhou, Yuli Qian, Yinzhi Lang, Yongzhen Zhang, Xun Tao, Bartolome Moya, Alaa R M Sayed, Cornelia B Landersdorfer, Eunjeong Shin, Carolin Werkman, Nicholas M Smith, Tae Hwan Kim, Monika Kumaraswamy, Beom Soo Shin, Brian T Tsuji, Robert A Bonomo, Richard E Lee, Juergen B Bulitta
Comprehensive stability analysis of 13 β-lactams and β-lactamase inhibitors in in vitro media, and novel supplement dosing strategy to mitigate thermal drug degradation. Antimicrobial agents and chemotherapy (2024)
Yu Zhu, Jing Gu, Zhuoran Zhao, Ah Wing Edith Chan, Maria F Mojica, Andrea M Hujer, Robert A Bonomo, Shozeb M Haider
Deciphering the Coevolutionary Dynamics of L2 β-Lactamases via Deep Learning. Journal of chemical information and modeling 64 (9) (2024)
Bradford Becken, Khalid M Dousa, John L Johnson, Steven M Holland, Robert A Bonomo
Dual β-lactam for treatment of pulmonary Mycobacterium abscessus in a child. Antimicrobial agents and chemotherapy 68 (7) (2024)
Daisuke Ono, María Fernanda Mojica, Christopher R Bethel, Yoshikazu Ishii, Salvador I Drusin, Diego Martín Moreno, Alejandro J Vila, Robert A Bonomo
Structural role of K224 in taniborbactam inhibition of NDM-1. Antimicrobial agents and chemotherapy 68 (2) (2024)
Barbara Ghiglione, María Margarita Rodríguez, Pedro Penzotti, Christopher R Bethel, Gabriel Gutkind, Robert A Bonomo, Sebastián Klinke, Pablo Power
Crystal structure of the class A extended-spectrum β-lactamase CTX-M-96 in complex with relebactam at 1.03 Angstrom resolution. Antimicrobial agents and chemotherapy 68 (8) (2024)
Mary Nantongo, David C Nguyen, Christopher R Bethel, Magdalena A Taracila, Qing Li, Khalid M Dousa, Eunjeong Shin, Sebastian G Kurz, Liem Nguyen, Barry N Kreiswirth, W Henry Boom, Mark S Plummer, Robert A Bonomo
Durlobactam, a Diazabicyclooctane β-Lactamase Inhibitor, Inhibits BlaC and Peptidoglycan Transpeptidases of Mycobacterium tuberculosis . ACS infectious diseases 10 (5) (2024)
Zishuo Cheng, Mahesh Aitha, Caitlyn A Thomas, Aidan Sturgill, Mitch Fairweather, Amy Hu, Christopher R Bethel, Dann D Rivera, Patricia Dranchak, Pei W Thomas, Han Li, Qi Feng, Kaicheng Tao, Minshuai Song, Na Sun, Shuo Wang, Surendra Bikram Silwal, Richard C Page, Walter Fast, Robert A Bonomo, Maria Weese, Waldyn Martinez, James Inglese, Michael W Crowder
Machine Learning Models Identify Inhibitors of New Delhi Metallo-β-lactamase. Journal of chemical information and modeling 64 (10) (2024)
Bradford Becken, Khalid M Dousa, John L Johnson, Steven M Holland, Robert A Bonomo
Dual β-lactam for treatment of pulmonary Mycobacterium abscessus in a child. Antimicrobial agents and chemotherapy (2024)
Mary Nantongo, David C Nguyen, Christopher R Bethel, Magdalena A Taracila, Qing Li, Khalid M Dousa, Eunjeong Shin, Sebastian G Kurz, Liem Nguyen, Barry N Kreiswirth, W Henry Boom, Mark S Plummer, Robert A Bonomo
Durlobactam, a Diazabicyclooctane β-Lactamase Inhibitor, Inhibits BlaC and Peptidoglycan Transpeptidases of Mycobacterium tuberculosis . ACS infectious diseases 10 (5) (2024)
Mary Nantongo, David C Nguyen, Christopher R Bethel, Magdalena A Taracila, Qing Li, Khalid M Dousa, Eunjeong Shin, Sebastian G Kurz, Liem Nguyen, Barry N Kreiswirth, W Henry Boom, Mark S Plummer, Robert A Bonomo
Durlobactam, a Diazabicyclooctane β-Lactamase Inhibitor, Inhibits BlaC and Peptidoglycan Transpeptidases of Mycobacterium tuberculosis . ACS infectious diseases 10 (5) (2024)
Daisuke Ono, María Fernanda Mojica, Christopher R Bethel, Yoshikazu Ishii, Salvador I Drusin, Diego Martín Moreno, Alejandro J Vila, Robert A Bonomo
Structural role of K224 in taniborbactam inhibition of NDM-1. Antimicrobial agents and chemotherapy 68 (2) (2024)
Barbara Ghiglione, María Margarita Rodríguez, Pedro Penzotti, Christopher R Bethel, Gabriel Gutkind, Robert A Bonomo, Sebastián Klinke, Pablo Power
Crystal structure of the class A extended-spectrum β-lactamase CTX-M-96 in complex with relebactam at 1.03 Angstrom resolution. Antimicrobial agents and chemotherapy (2024)
Jieqiang Zhou, Yuli Qian, Yinzhi Lang, Yongzhen Zhang, Xun Tao, Bartolome Moya, Alaa R M Sayed, Cornelia B Landersdorfer, Eunjeong Shin, Carolin Werkman, Nicholas M Smith, Tae Hwan Kim, Monika Kumaraswamy, Beom Soo Shin, Brian T Tsuji, Robert A Bonomo, Richard E Lee, Juergen B Bulitta
Comprehensive stability analysis of 13 β-lactams and β-lactamase inhibitors in in vitro media, and novel supplement dosing strategy to mitigate thermal drug degradation. Antimicrobial agents and chemotherapy 68 (3) (2024)
Valentina Villamil, Maria-Agustina Rossi, Maria F Mojica, Philip Hinchliffe, Verónica Martínez, Valerie Castillo, Cecilia Saiz, Claudia Banchio, Mario A Macías, James Spencer, Robert A Bonomo, Alejandro Vila, Diego Martín Moreno, Graciela Mahler
Rational Design of Benzobisheterocycle Metallo-β-Lactamase Inhibitors: A Tricyclic Scaffold Enhances Potency against Target Enzymes. Journal of medicinal chemistry 67 (5) (2024)
Zishuo Cheng, Mahesh Aitha, Caitlyn A Thomas, Aidan Sturgill, Mitch Fairweather, Amy Hu, Christopher R Bethel, Dann D Rivera, Patricia Dranchak, Pei W Thomas, Han Li, Qi Feng, Kaicheng Tao, Minshuai Song, Na Sun, Shuo Wang, Surendra Bikram Silwal, Richard C Page, Walter Fast, Robert A Bonomo, Maria Weese, Waldyn Martinez, James Inglese, Michael W Crowder
Machine Learning Models Identify Inhibitors of New Delhi Metallo-β-lactamase. Journal of chemical information and modeling 64 (10) (2024)
Zishuo Cheng, Mahesh Aitha, Caitlyn A Thomas, Aidan Sturgill, Mitch Fairweather, Amy Hu, Christopher R Bethel, Dann D Rivera, Patricia Dranchak, Pei W Thomas, Han Li, Qi Feng, Kaicheng Tao, Minshuai Song, Na Sun, Shuo Wang, Surendra Bikram Silwal, Richard C Page, Walter Fast, Robert A Bonomo, Maria Weese, Waldyn Martinez, James Inglese, Michael W Crowder
Machine Learning Models Identify Inhibitors of New Delhi Metallo-β-lactamase. Journal of chemical information and modeling 64 (10) (2024)
Barbara Ghiglione, María Margarita Rodríguez, Pedro Penzotti, Christopher R Bethel, Gabriel Gutkind, Robert A Bonomo, Sebastián Klinke, Pablo Power
Crystal structure of the class A extended-spectrum β-lactamase CTX-M-96 in complex with relebactam at 1.03 Angstrom resolution. Antimicrobial agents and chemotherapy 68 (8) (2024)
Daisuke Ono, María Fernanda Mojica, Christopher R Bethel, Yoshikazu Ishii, Salvador I Drusin, Diego Martín Moreno, Alejandro J Vila, Robert A Bonomo
Structural role of K224 in taniborbactam inhibition of NDM-1. Antimicrobial agents and chemotherapy (2024)
Yu Zhu, Jing Gu, Zhuoran Zhao, Ah Wing Edith Chan, Maria F Mojica, Andrea M Hujer, Robert A Bonomo, Shozeb M Haider
Deciphering the Coevolutionary Dynamics of L2 β-Lactamases via Deep Learning. Journal of chemical information and modeling (2024)
Morgan K Morelli, Amy Kloosterboer, Scott A Fulton, Jennifer Furin, Nicholas Newman, Ahmed F Omar, Laura J Rojas, Steven H Marshall, Mohamad Yasmin, Robert A Bonomo
Investigating and Treating a Corneal Ulcer Due to Extensively Drug-Resistant Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy (2023)
T A Alsenani, S L Viviani, Krisztina M Papp-Wallace, Robert A Bonomo, Focco van den Akker
Exploring avibactam and relebactam inhibition of Klebsiella pneumoniae carbapenemase D179N variant: role of the Ω loop-held deacylation water. Antimicrobial agents and chemotherapy (2023)
Yinong Young-Xu, Caroline Korves, Gabrielle Zwain, Sacha Satram, Myriam Drysdale, Carolina Reyes, Mindy M Cheng, Robert A Bonomo, Lauren Epstein, Vincent C Marconi, Adit A Ginde
Effectiveness of Sotrovimab in Preventing COVID-19-Related Hospitalizations or Deaths Among US Veterans During Omicron BA.1. Open forum infectious diseases 10 (12) (2023)
Lisa T Hong, Kevin James Downes, Alireza FakhriRavari, Jacinda C Abdul-Mutakabbir, Joseph L Kuti, Sarah C J Jorgensen, David C Young, Mohammad H Alshaer, Matteo Bassetti, Robert A Bonomo, Mark Gilchrist, Soo Min Jang, Thomas P Lodise, Jason Alexander Roberts, Thomas Tängdén, Athena Zuppa, Marc H Scheetz
International consensus recommendations for the use of prolonged-infusion beta-lactam antibiotics: Endorsed by the American College of Clinical Pharmacy, British Society for Antimicrobial Chemotherapy, Cystic Fibrosis Foundation, European Society of Clinical Microbiology and Infectious Diseases, Infectious Diseases Society of America, Society of Critical Care Medicine, and Society of Infectious Diseases Pharmacists. Pharmacotherapy 43 (8) (2023)
Lisa T Hong, Kevin James Downes, Alireza FakhriRavari, Jacinda C Abdul-Mutakabbir, Joseph L Kuti, Sarah C J Jorgensen, David C Young, Mohammad H Alshaer, Matteo Bassetti, Robert A Bonomo, Mark Gilchrist, Soo Min Jang, Thomas P Lodise, Jason Alexander Roberts, Thomas Tängdén, Athena Zuppa, Marc H Scheetz
International consensus recommendations for the use of prolonged-infusion beta-lactam antibiotics: Endorsed by the American College of Clinical Pharmacy, British Society for Antimicrobial Chemotherapy, Cystic Fibrosis Foundation, European Society of Clinical Microbiology and Infectious Diseases, Infectious Diseases Society of America, Society of Critical Care Medicine, and Society of Infectious Diseases Pharmacists: An executive summary. Pharmacotherapy 43 (8) (2023)
Tahani A Alsenani, María Margarita Rodríguez, Barbara Ghiglione, Magdalena A Taracila, Maria F Mojica, Laura J Rojas, Andrea M Hujer, Gabriel Gutkind, Christopher R Bethel, Philip N Rather, Maria Luisa Introvigne, Fabio Prati, Emilia Caselli, Pablo Power, Focco van den Akker, Robert A Bonomo
Boronic Acid Transition State Inhibitors as Potent Inactivators of KPC and CTX-M β-Lactamases: Biochemical and Structural Analyses. Antimicrobial agents and chemotherapy 67 (1) (2023)
Tahani A Alsenani, María Margarita Rodríguez, Barbara Ghiglione, Magdalena A Taracila, Maria F Mojica, Laura J Rojas, Andrea M Hujer, Gabriel Gutkind, Christopher R Bethel, Philip N Rather, Maria Luisa Introvigne, Fabio Prati, Emilia Caselli, Pablo Power, Focco van den Akker, Robert A Bonomo
Boronic Acid Transition State Inhibitors as Potent Inactivators of KPC and CTX-M β-Lactamases: Biochemical and Structural Analyses. Antimicrobial agents and chemotherapy 67 (1) (2023)

Robert A Bonomo.css-eqlu8i{font-size:small;padding-left:4px;} (R A Bonomo)

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Robert A Bonomo (R A Bonomo)