James W Dear (J W Dear, James Dear, J Dear)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 34

Top Topics

Anti Inflammatory

Top Venues

British journal of clinical pharmacology

Nature communications

Science translational medicine

Clinical toxicology (Philadelphia, Pa.)

This page only lists publications with an associated author ORCID identifier.

Publications

Susan K Armstrong, Robert W Hunter, Wilna Oosthyuzen, Maciej Parys, Adam George Gow, Silke Salavati Schmitz, James W Dear, Richard John Mellanby
Candidate circulating microRNA biomarkers in dogs with chronic pancreatitis. Journal of veterinary internal medicine (2024)
D Nicholas Bateman, Richard C Dart, James W Dear, Laurie F Prescott, Barry H Rumack
Fifty years of paracetamol (acetaminophen) poisoning: the development of risk assessment and treatment 1973-2023 with particular focus on contributions published from Edinburgh and Denver. Clinical toxicology (Philadelphia, Pa.) 61 (12) (2024)
D Nicholas Bateman, Richard C Dart, James W Dear, Laurie F Prescott, Barry H Rumack
Fifty years of paracetamol (acetaminophen) poisoning: the development of risk assessment and treatment 1973-2023 with particular focus on contributions published from Edinburgh and Denver. Clinical toxicology (Philadelphia, Pa.) 61 (12) (2024)
Susan K Armstrong, Robert W Hunter, Wilna Oosthyuzen, Maciej Parys, Adam George Gow, Silke Salavati Schmitz, James W Dear, Richard John Mellanby
Candidate circulating microRNA biomarkers in dogs with chronic pancreatitis. Journal of veterinary internal medicine 38 (2) (2024)
D Nicholas Bateman, Richard C Dart, James W Dear, Laurie F Prescott, Barry H Rumack
Fifty years of paracetamol (acetaminophen) poisoning: the development of risk assessment and treatment 1973-2023 with particular focus on contributions published from Edinburgh and Denver. Clinical toxicology (Philadelphia, Pa.) (2024)
Susan K Armstrong, Robert W Hunter, Wilna Oosthyuzen, Maciej Parys, Adam George Gow, Silke Salavati Schmitz, James W Dear, Richard John Mellanby
Candidate circulating microRNA biomarkers in dogs with chronic pancreatitis. Journal of veterinary internal medicine 38 (2) (2024)
Susan K Armstrong, Robert W Hunter, Wilna Oosthyuzen, Maciej Parys, Adam George Gow, Silke Salavati Schmitz, James W Dear, Richard John Mellanby
Candidate circulating microRNA biomarkers in dogs with chronic pancreatitis. Journal of veterinary internal medicine 38 (2) (2024)
Kodihalli C Ravindra, Vishal S Vaidya, Zhenyu Wang, Joel D Federspiel, Richard Virgen-Slane, Robert A Everley, Jane I Grove, Camilla Stephens, Mireia F Ocana, Mercedes Robles-Díaz, María Isabel Lucena, Raúl Jesús Andrade, Edmond Atallah, Alexander L Gerbes, Sabine Weber, Helena Cortez-Pinto, Andrew J Fowell, Hyder Hussaini, Einar S Bjornsson, Janisha Patel, Guido Stirnimann, Sumita Verma, Ahmed M Elsharkawy, William J H Griffiths, Craig L Hyde, James W Dear, Guruprasad Padur Aithal, Shashi K Ramaiah
Tandem mass tag-based quantitative proteomic profiling identifies candidate serum biomarkers of drug-induced liver injury in humans. Nature communications 14 (1) (2023)
Kodihalli C Ravindra, Vishal S Vaidya, Zhenyu Wang, Joel D Federspiel, Richard Virgen-Slane, Robert A Everley, Jane I Grove, Camilla Stephens, Mireia F Ocana, Mercedes Robles-Díaz, María Isabel Lucena, Raúl Jesús Andrade, Edmond Atallah, Alexander L Gerbes, Sabine Weber, Helena Cortez-Pinto, Andrew J Fowell, Hyder Hussaini, Einar S Bjornsson, Janisha Patel, Guido Stirnimann, Sumita Verma, Ahmed M Elsharkawy, William J H Griffiths, Craig L Hyde, James W Dear, Guruprasad Padur Aithal, Shashi K Ramaiah
Tandem mass tag-based quantitative proteomic profiling identifies candidate serum biomarkers of drug-induced liver injury in humans. Nature communications 14 (1) (2023)
Kodihalli C Ravindra, Vishal S Vaidya, Zhenyu Wang, Joel D Federspiel, Richard Virgen-Slane, Robert A Everley, Jane I Grove, Camilla Stephens, Mireia F Ocana, Mercedes Robles-Díaz, María Isabel Lucena, Raúl Jesús Andrade, Edmond Atallah, Alexander L Gerbes, Sabine Weber, Helena Cortez-Pinto, Andrew J Fowell, Hyder Hussaini, Einar S Bjornsson, Janisha Patel, Guido Stirnimann, Sumita Verma, Ahmed M Elsharkawy, William J H Griffiths, Craig L Hyde, James W Dear, Guruprasad Padur Aithal, Shashi K Ramaiah
Tandem mass tag-based quantitative proteomic profiling identifies candidate serum biomarkers of drug-induced liver injury in humans. Nature communications 14 (1) (2023)
Tariq E Farrah, Dan Pugh, Fiona A Chapman, Emily Godden, Craig Balmforth, Gabriel C Oniscu, David John Webb, Baljean Dhillon, James W Dear, Matthew A Bailey, Peter J Gallacher, Neeraj Dhaun
Choroidal and retinal thinning in chronic kidney disease independently associate with eGFR decline and are modifiable with treatment. Nature communications 14 (1) (2023)
Eleanor Grace Dixon, Shaista Rasool, Brian Otaalo, Ashmika Motee, James W Dear, Derek Sloan, Helen R Stagg
No action is without its side effects: adverse drug reactions and missed doses of anti-tuberculosis therapy, a scoping review. British journal of clinical pharmacology (2023)
Kodihalli C Ravindra, Vishal S Vaidya, Zhenyu Wang, Joel D Federspiel, Richard Virgen-Slane, Robert A Everley, Jane I Grove, Camilla Stephens, Mireia F Ocana, Mercedes Robles-Díaz, María Isabel Lucena, Raúl Jesús Andrade, Edmond Atallah, Alexander L Gerbes, Sabine Weber, Helena Cortez-Pinto, Andrew J Fowell, Hyder Hussaini, Einar S Bjornsson, Janisha Patel, Guido Stirnimann, Sumita Verma, Ahmed M Elsharkawy, William J H Griffiths, Craig L Hyde, James W Dear, Guruprasad Padur Aithal, Shashi K Ramaiah
Tandem mass tag-based quantitative proteomic profiling identifies candidate serum biomarkers of drug-induced liver injury in humans. Nature communications 14 (1) (2023)
Luke D Tyson, Stephen Atkinson, Robert W Hunter, Michael Allison, Andrew Austin, James W Dear, Ewan H Forrest, Tong Liu, Emma Lord, Steven Masson, Joao Nunes, Paul Richardson, Stephen D Ryder, Mark Wright, Mark Thursz, Nikhil Vergis
In severe alcohol-related hepatitis, acute kidney injury is prevalent, associated with mortality independent of liver disease severity, and can be predicted using IL-8 and micro-RNAs. Alimentary pharmacology & therapeutics (2023)
Priyanga Ranasinghe, Melisande L Addison, James W Dear, David John Webb
Small interfering RNA: Discovery, pharmacology and clinical development-An introductory review. British journal of pharmacology (2022)
Robert Likić, James W Dear, Lionel D Lewis
Spotlight commentary: Navigating between financial risks and improved treatment outcomes with immune checkpoint inhibitors in cancer patients: The need for biomarker identification and dose optimization. British journal of clinical pharmacology 88 (12) (2022)
Alicja Czopek, Rebecca Moorhouse, Peter J Gallacher, Dan Pugh, Jessica R Ivy, Tariq E Farrah, Emily Godden, Robert W Hunter, David John Webb, Pierre-Louis Tharaux, David C Kluth, James W Dear, Matthew A Bailey, Neeraj Dhaun
Endothelin blockade prevents the long-term cardiovascular and renal sequelae of acute kidney injury in mice. Science translational medicine 14 (675) (2022)
Alicja Czopek, Rebecca Moorhouse, Peter J Gallacher, Dan Pugh, Jessica R Ivy, Tariq E Farrah, Emily Godden, Robert W Hunter, David John Webb, Pierre-Louis Tharaux, David C Kluth, James W Dear, Matthew A Bailey, Neeraj Dhaun
Endothelin blockade prevents the long-term cardiovascular and renal sequelae of acute kidney injury in mice. Science translational medicine 14 (675) (2022)
James W Dear
Fomepizole should not be used more liberally in paracetamol overdose. British journal of clinical pharmacology (2022)
Alicja Czopek, Rebecca Moorhouse, Peter J Gallacher, Dan Pugh, Jessica R Ivy, Tariq E Farrah, Emily Godden, Robert W Hunter, David John Webb, Pierre-Louis Tharaux, David C Kluth, James W Dear, Matthew A Bailey, Neeraj Dhaun
Endothelin blockade prevents the long-term cardiovascular and renal sequelae of acute kidney injury in mice. Science translational medicine 14 (675) (2022)
Alicja Czopek, Rebecca Moorhouse, Peter J Gallacher, Dan Pugh, Jessica R Ivy, Tariq E Farrah, Emily Godden, Robert W Hunter, David John Webb, Pierre-Louis Tharaux, David C Kluth, James W Dear, Matthew A Bailey, Neeraj Dhaun
Endothelin blockade prevents the long-term cardiovascular and renal sequelae of acute kidney injury in mice. Science translational medicine 14 (675) (2022)
Alicja Czopek, Rebecca Moorhouse, Peter J Gallacher, Dan Pugh, Jessica R Ivy, Tariq E Farrah, Emily Godden, Robert W Hunter, David John Webb, Pierre-Louis Tharaux, David C Kluth, James W Dear, Matthew A Bailey, Neeraj Dhaun
Endothelin blockade prevents the long-term cardiovascular and renal sequelae of acute kidney injury in mice. Science translational medicine 14 (675) (2022)
Irene González-Recio, Jorge Simón, Naroa Goikoetxea-Usandizaga, Marina Serrano-Maciá, Maria Mercado-Gómez, Rubén Rodríguez-Agudo, Sofia Lachiondo-Ortega, Clàudia Gil-Pitarch, Carmen Fernández-Rodríguez, Donatello Castellana, Maria U Latasa, Leticia Abecia, Juan Anguita, Teresa Cardoso Delgado, Paula Iruzubieta, Javier Crespo, Serge Hardy, Petar D Petrov, Ramiro Jover, Matias A Avila, César Martín, Ute Schaeper, Michel L Tremblay, James W Dear, Steven Masson, Misti Vanette McCain, Helen L Reeves, Raúl Jesús Andrade, María Isabel Lucena, Debra R Rooker, Luis Alfonso Martinez-Cruz, María Luz Martínez-Chantar
Restoring cellular magnesium balance through Cyclin M4 protects against acetaminophen-induced liver damage. Nature communications 13 (1) (2022)
Robert W Hunter, James W Dear
Urinary Vesicles: Are They Ready for Real-World Use? Journal of the American Society of Nephrology : JASN 32 (5) (2021)
Anissa Anindya Widjaja, Jinrui Dong, Eleonora Adami, Sivakumar Viswanathan, Benjamin Ng, Leroy S Pakkiri, Sonia P Chothani, Brijesh Kumar Singh, Wei Wen Lim, Jin Zhou, Shamini G Shekeran, Jessie Tan, Sze Yun Lim, Joyce Goh, Mao Wang, Robert Holgate, Arron Hearn, Leanne E Felkin, Paul M Yen, James W Dear, Chester Lee Drum, Sebastian Schafer, Stuart Alexander Cook
Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury. Science translational medicine 13 (597) (2021)
Sarah A E Rupprechter, Derek J Sloan, Wilna Oosthuyzen, Till T Bachmann, Adam T Hill, Kevin Dhaliwal, Kate Templeton, Joshua Matovu, Christine Sekaggya-Wiltshire, James W Dear
MicroRNA-122 and cytokeratin-18 have potential as a biomarkers of drug-induced liver injury in European and African patients on treatment for mycobacterial infection. British journal of clinical pharmacology 87 (8) (2021)
James W Dear, Paul I Dargan, David N Juurlink, H K Ruben Thanacoody, David M Wood
Introduction to a series of Pro/Con papers in Clinical Toxicology. British journal of clinical pharmacology (2021)
D Nicholas Bateman, James W Dear, Michael Eddleston, J Allister Vale
Comment on Fomepizole as an adjunctive treatment in severe acetaminophen ingestions. Clinical toxicology (Philadelphia, Pa.) 59 (1) (2020)
Karen Osinski, H Ross, L Clarke, James W Dear, A Veiraiah
A case of ingestion of two vape cartridges. Clinical toxicology (Philadelphia, Pa.) 59 (7) (2020)
null null, James W Dear
Randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with the 12-h regimen of N-acetylcysteine for paracetamol overdose-the PP100-01 for Overdose of Paracetamol (POP) trial: study protocol for a randomised controlled trial. Trials 20 (1) (2019)
Thomas M Caparrotta, James W Dear, Helen Martina Colhoun, David John Webb
Pharmacoepidemiology: Using randomised control trials and observational studies in clinical decision-making. British journal of clinical pharmacology 85 (9) (2019)
D Nicholas Bateman, James W Dear
Acetylcysteine in paracetamol poisoning: a perspective of 45 years of use. Toxicology research 8 (4) (2019)
W Oosthuyzen, P W L Ten Berg, B Francis, S Campbell, V Macklin, E Milne, A G Gow, C Fisher, R J Mellanby, James W Dear
Sensitivity and specificity of microRNA-122 for liver disease in dogs. Journal of veterinary internal medicine 32 (5) (2018)
J C McCrae, E E Morrison, Iain M MacIntyre, James W Dear, David John Webb
Long-term adverse effects of paracetamol - a review. British journal of clinical pharmacology 84 (10) (2018)