Jack B Greisman

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 26

Top Topics

Molecular Dynamics Simulations

Magnetic Resonance

Top Venues

Journal of chemical information and modeling

Proceedings of the National Academy of Sciences of the United States of America

Nature communications

bioRxiv : the preprint server for biology

This page only lists publications with an associated author ORCID identifier.

Publications

Jack B Greisman, Kevin M Dalton, Dennis E Brookner, Margaret A Klureza, Candice J Sheehan, In-Sik Kim, Robert W Henning, Silvia Russi, Doeke R Hekstra
Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Jack B Greisman, Kevin M Dalton, Dennis E Brookner, Margaret A Klureza, Candice J Sheehan, In-Sik Kim, Robert W Henning, Silvia Russi, Doeke R Hekstra
Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Rick A Hewitt, Kevin M Dalton, Derek Mendez, Harrison K Wang, Margaret A Klureza, Dennis E Brookner, Jack B Greisman, David McDonagh, Vukica Šrajer, Nicholas K Sauter, Aaron S Brewster, Doeke R Hekstra
Laue-DIALS: open-source software for polychromatic X-ray diffraction data. bioRxiv : the preprint server for biology (2024)
Jack B Greisman, Kevin M Dalton, Dennis E Brookner, Margaret A Klureza, Candice J Sheehan, In-Sik Kim, Robert W Henning, Silvia Russi, Doeke R Hekstra
Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Doeke R Hekstra, Harrison K Wang, Margaret A Klureza, Jack B Greisman, Kevin M Dalton
Sensitive Detection of Structural Differences using a Statistical Framework for Comparative Crystallography. bioRxiv : the preprint server for biology (2024)
Doeke R Hekstra, Harrison K Wang, Margaret A Klureza, Jack B Greisman, Kevin M Dalton
Sensitive Detection of Structural Differences using a Statistical Framework for Comparative Crystallography. bioRxiv : the preprint server for biology (2024)
Rick A Hewitt, Kevin M Dalton, Derek Mendez, Harrison K Wang, Margaret A Klureza, Dennis E Brookner, Jack B Greisman, David McDonagh, Vukica Šrajer, Nicholas K Sauter, Aaron S Brewster, Doeke R Hekstra
Laue-DIALS: open-source software for polychromatic X-ray diffraction data. bioRxiv : the preprint server for biology (2024)
Jack B Greisman, Kevin M Dalton, Dennis E Brookner, Margaret A Klureza, Candice J Sheehan, In-Sik Kim, Robert W Henning, Silvia Russi, Doeke R Hekstra
Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Jack B Greisman, Kevin M Dalton, Dennis E Brookner, Margaret A Klureza, Candice J Sheehan, In-Sik Kim, Robert W Henning, Silvia Russi, Doeke R Hekstra
Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Alexander M Taylor, Bret R Williams, Fabrizio Giordanetto, Elizabeth H Kelley, André Lescarbeau, Kelley Shortsleeves, Yong Tang, W Patrick Walters, Alfonso Arrazate, Christine Bowman, Erin Brophy, Emily W Chan, Gauri Deshmukh, Jack B Greisman, Thomas L Hunsaker, D Randal Kipp, Pablo Saenz Lopez-Larrocha, Danilo Maddalo, Iain J Martin, Paul Maragakis, Mark Merchant, Mark Murcko, Hunter M Nisonoff, Vi Nguyen, Vy Nguyen, Olivia Orozco, Christopher Owen, Levi Pierce, Molly Schmidt, David E Shaw, Sherri Smith, Eric Therrien, John C Tran, Jim Watters, Nigel J Waters, Jeremy Wilbur, Lindsay Willmore
Identification of GDC-1971 (RLY-1971), a SHP2 Inhibitor Designed for the Treatment of Solid Tumors. Journal of medicinal chemistry (2023)
Jack B Greisman, Lindsay Willmore, Christine Yiwen Yeh, Fabrizio Giordanetto, Sahar Shahamadtar, Hunter Nisonoff, Paul Maragakis, David E Shaw
Discovery and Validation of the Binding Poses of Allosteric Fragment Hits to Protein Tyrosine Phosphatase 1b: From Molecular Dynamics Simulations to X-ray Crystallography. Journal of chemical information and modeling 63 (9) (2023)
Jack B Greisman, Kevin M Dalton, Dennis E Brookner, Margaret A Klureza, Candice J Sheehan, In-Sik Kim, Robert W Henning, Silvia Russi, Doeke R Hekstra
Resolving conformational changes that mediate a two-step catalytic mechanism in a model enzyme. bioRxiv : the preprint server for biology (2023)
Jack B Greisman, Lindsay Willmore, Christine Yiwen Yeh, Fabrizio Giordanetto, Sahar Shahamadtar, Hunter Nisonoff, Paul Maragakis, David E Shaw
Discovery and Validation of the Binding Poses of Allosteric Fragment Hits to Protein Tyrosine Phosphatase 1b: From Molecular Dynamics Simulations to X-ray Crystallography. Journal of chemical information and modeling (2023)
Jack B Greisman, Lindsay Willmore, Christine Yiwen Yeh, Fabrizio Giordanetto, Sahar Shahamadtar, Hunter Nisonoff, Paul Maragakis, David E Shaw
Discovery and Validation of the Binding Poses of Allosteric Fragment Hits to Protein Tyrosine Phosphatase 1b: From Molecular Dynamics Simulations to X-ray Crystallography. Journal of chemical information and modeling 63 (9) (2023)
Jack B Greisman, Lindsay Willmore, Christine Yiwen Yeh, Fabrizio Giordanetto, Sahar Shahamadtar, Hunter Nisonoff, Paul Maragakis, David E Shaw
Discovery and Validation of the Binding Poses of Allosteric Fragment Hits to Protein Tyrosine Phosphatase 1b: From Molecular Dynamics Simulations to X-ray Crystallography. Journal of chemical information and modeling (2023)
Jack B Greisman, Lindsay Willmore, Christine Yiwen Yeh, Fabrizio Giordanetto, Sahar Shahamadtar, Hunter Nisonoff, Paul Maragakis, David E Shaw
Discovery and Validation of the Binding Poses of Allosteric Fragment Hits to Protein Tyrosine Phosphatase 1b: From Molecular Dynamics Simulations to X-ray Crystallography. Journal of chemical information and modeling (2023)
Jack B Greisman, Lindsay Willmore, Christine Yiwen Yeh, Fabrizio Giordanetto, Sahar Shahamadtar, Hunter Nisonoff, Paul Maragakis, David E Shaw
Discovery and Validation of the Binding Poses of Allosteric Fragment Hits to Protein Tyrosine Phosphatase 1b: From Molecular Dynamics Simulations to X-ray Crystallography. Journal of chemical information and modeling 63 (9) (2023)
Jack B Greisman, Lindsay Willmore, Christine Yiwen Yeh, Fabrizio Giordanetto, Sahar Shahamadtar, Hunter Nisonoff, Paul Maragakis, David E Shaw
Discovery and Validation of the Binding Poses of Allosteric Fragment Hits to Protein Tyrosine Phosphatase 1b: From Molecular Dynamics Simulations to X-ray Crystallography. Journal of chemical information and modeling 63 (9) (2023)
Christine Yiwen Yeh, Jesus A Izaguirre, Jack B Greisman, Lindsay Willmore, Paul Maragakis, David E Shaw
A Conserved Local Structural Motif Controls the Kinetics of PTP1B Catalysis. Journal of chemical information and modeling (2023)
Jack B Greisman, Kevin M Dalton, Candice J Sheehan, Margaret A Klureza, Igor Kurinov, Doeke R Hekstra
Native SAD phasing at room temperature. Acta crystallographica. Section D, Structural biology 78 (Pt 8) (2022)
Kevin M Dalton, Jack B Greisman, Doeke R Hekstra
A unifying Bayesian framework for merging X-ray diffraction data. Nature communications 13 (1) (2022)
Kevin M Dalton, Jack B Greisman, Doeke R Hekstra
A unifying Bayesian framework for merging X-ray diffraction data. Nature communications 13 (1) (2022)
Kevin M Dalton, Jack B Greisman, Doeke R Hekstra
A unifying Bayesian framework for merging X-ray diffraction data. Nature communications 13 (1) (2022)
Kevin M Dalton, Jack B Greisman, Doeke R Hekstra
A unifying Bayesian framework for merging X-ray diffraction data. Nature communications 13 (1) (2022)
Kevin M Dalton, Jack B Greisman, Doeke R Hekstra
A unifying Bayesian framework for merging X-ray diffraction data. Nature communications 13 (1) (2022)
Jack B Greisman, Kevin M Dalton, Doeke R Hekstra
reciprocalspaceship: a Python library for crystallographic data analysis. Journal of applied crystallography 54 (Pt 5) (2021)