Jack Hearn

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 22

Top Topics

Plasmodium Falciparum

Molecularly Imprinted

Gene Expression

Top Venues

Molecular ecology

Journal of applied microbiology

This page only lists publications with an associated author ORCID identifier.

Publications

Leon M J Mugenzi, Theofelix A Tekoh, Stevia T Ntadoun, Achille D Chi, Mahamat Gadji, Benjamin D Menze, Magellan Tchouakui, Helen Irving, Murielle J Wondji, Gareth D Weedall, Jack Hearn, Charles S Wondji
Association of a rapidly selected 4.3kb transposon-containing structural variation with a P450-based resistance to pyrethroids in the African malaria vector Anopheles funestus. PLoS genetics 20 (7) (2024)
Leon M J Mugenzi, Theofelix A Tekoh, Stevia T Ntadoun, Achille D Chi, Mahamat Gadji, Benjamin D Menze, Magellan Tchouakui, Helen Irving, Murielle J Wondji, Gareth D Weedall, Jack Hearn, Charles S Wondji
Association of a rapidly selected 4.3kb transposon-containing structural variation with a P450-based resistance to pyrethroids in the African malaria vector Anopheles funestus. PLoS genetics 20 (7) (2024)
Leon M J Mugenzi, Theofelix A Tekoh, Stevia T Ntadoun, Achille D Chi, Mahamat Gadji, Benjamin D Menze, Magellan Tchouakui, Helen Irving, Murielle J Wondji, Gareth D Weedall, Jack Hearn, Charles S Wondji
Association of a rapidly selected 4.3kb transposon-containing structural variation with a P450-based resistance to pyrethroids in the African malaria vector Anopheles funestus. PLoS genetics 20 (7) (2024)
Leon M J Mugenzi, Theofelix A Tekoh, Stevia T Ntadoun, Achille D Chi, Mahamat Gadji, Benjamin D Menze, Magellan Tchouakui, Helen Irving, Murielle J Wondji, Gareth D Weedall, Jack Hearn, Charles S Wondji
Association of a rapidly selected 4.3kb transposon-containing structural variation with a P450-based resistance to pyrethroids in the African malaria vector Anopheles funestus. PLoS genetics 20 (7) (2024)
Leon M J Mugenzi, Theofelix A Tekoh, Sulaiman S Ibrahim, Abdullahi Muhammad, Mersimine Kouamo, Murielle J Wondji, Helen Irving, Jack Hearn, Charles Sinclair Wondji
The duplicated P450s CYP6P9a/b drive carbamates and pyrethroids cross-resistance in the major African malaria vector Anopheles funestus. PLoS genetics 19 (3) (2023)
Jack Hearn, Carlos S Djoko Tagne, Sulaiman S Ibrahim, Billy Tene-Fossog, Leon M J Mugenzi, Helen Irving, Jacob M Riveron, Gareth D Weedall, Charles Sinclair Wondji
Multi-omics analysis identifies a CYP9K1 haplotype conferring pyrethroid resistance in the malaria vector Anopheles funestus in East Africa. Molecular ecology 31 (13) (2022)
Jack Hearn, Jacob M Riveron, Helen Irving, Gareth D Weedall, Charles Sinclair Wondji
Gene Conversion Explains Elevated Diversity in the Immunity Modulating APL1 Gene of the Malaria Vector Anopheles funestus . Genes 13 (6) (2022)
Rachel L Byrne, Derek Cocker, Ghaith Alyayyoussi, Madalitso Mphasa, Mary Charles, Tamandani Mandula, Christopher T Williams, Jonathan Rigby, Jack Hearn, Nicholas Feasey, Emily R Adams, Thomas Edwards
A novel, magnetic bead-based extraction method for the isolation of antimicrobial resistance genes with a case study in river water in Malawi. Journal of applied microbiology 133 (5) (2022)
Charles Sinclair Wondji, Jack Hearn, Helen Irving, Murielle J Wondji, Gareth Weedall
RNAseq-based gene expression profiling of the Anopheles funestus pyrethroid-resistant strain FUMOZ highlights the predominant role of the duplicated CYP6P9a/b cytochrome P450s. G3 (Bethesda, Md.) (2021)
Mersimine F M Kouamo, Sulaiman S Ibrahim, Jack Hearn, Jacob M Riveron, Michael O Kusimo, Magellan Tchouakui, Terence Ebai, Williams Tchapga, Murielle J Wondji, Helen Irving, Thaddée Boudjeko, Fabrice Fekam Boyom, Charles Sinclair Wondji
Genome-Wide Transcriptional Analysis and Functional Validation Linked a Cluster of Epsilon Glutathione S-Transferases with Insecticide Resistance in the Major Malaria Vector Anopheles funestus across Africa. Genes 12 (4) (2021)
Nicholas Wheelhouse, Jack Hearn, Morag Livingstone, Allen Flockhart, Mark Dagleish, David Longbottom
Identification of Parachlamydiaceae DNA in nasal and rectal passages of healthy dairy cattle. Journal of applied microbiology 132 (4) (2021)
Jack Hearn, Fiona Plenderleith, Tom J Little
DNA methylation differs extensively between strains of the same geographical origin and changes with age in Daphnia magna. Epigenetics & chromatin 14 (1) (2021)
Lisa Cooper, Lynsey Bunnefeld, Jack Hearn, James M Cook, Konrad Lohse, Graham N Stone
Low-coverage genomic data resolve the population divergence and gene flow history of an Australian rain forest fig wasp. Molecular ecology 29 (19) (2020)
Gareth D Weedall, Jacob M Riveron, Jack Hearn, Helen Irving, Colince Kamdem, Caroline Fouet, Bradley J White, Charles Sinclair Wondji
An Africa-wide genomic evolution of insecticide resistance in the malaria vector Anopheles funestus involves selective sweeps, copy number variations, gene conversion and transposons. PLoS genetics 16 (6) (2020)
Sulaiman S Ibrahim, Muhammad M Mukhtar, Helen Irving, Jacob M Riveron, Amen N Fadel, Williams Tchapga, Jack Hearn, Abdullahi Muhammad, Faruk Sarkinfada, Charles Sinclair Wondji
Exploring the Mechanisms of Multiple Insecticide Resistance in a Highly Plasmodium-Infected Malaria Vector Anopheles funestus Sensu Stricto from Sahel of Northern Nigeria. Genes 11 (4) (2020)
Jack Hearn, Jessica Clark, Philip J Wilson, Thomas J Little
Daphnia magna modifies its gene expression extensively in response to caloric restriction revealing a novel effect on haemoglobin isoform preference. Molecular ecology 29 (17) (2020)
Leon M J Mugenzi, Benjamin D Menze, Magellan Tchouakui, Murielle J Wondji, Helen Irving, Micareme Tchoupo, Jack Hearn, Gareth D Weedall, Jacob M Riveron, Fidelis Cho-Ngwa, Charles S Wondji
A 6.5-kb intergenic structural variation enhances P450-mediated resistance to pyrethroids in malaria vectors lowering bed net efficacy. Molecular ecology 29 (22) (2020)
Delia Doreen Djuicy, Jack Hearn, Magellan Tchouakui, Murielle J Wondji, Helen Irving, Fredros O Okumu, Charles Sinclair Wondji
CYP6P9-Driven Signatures of Selective Sweep of Metabolic Resistance to Pyrethroids in the Malaria Vector Anopheles funestus Reveal Contemporary Barriers to Gene Flow. Genes 11 (11) (2020)
Jack Hearn, Mark L Blaxter, Karsten Schönrogge, José-Luis Nieves-Aldrey, Juli Pujade-Villar, Elisabeth Huguet, Jean-Michel Drezen, Joseph D Shorthouse, Graham N Stone
Genomic dissection of an extended phenotype: Oak galling by a cynipid gall wasp. PLoS genetics 15 (11) (2019)
Leon M J Mugenzi, Benjamin D Menze, Magellan Tchouakui, Murielle J Wondji, Helen Irving, Micareme Tchoupo, Jack Hearn, Gareth D Weedall, Jacob M Riveron, Charles Sinclair Wondji
Cis-regulatory CYP6P9b P450 variants associated with loss of insecticide-treated bed net efficacy against Anopheles funestus. Nature communications 10 (1) (2019)
Jack Hearn, Marianne Pearson, Mark Blaxter, Philip J Wilson, Tom J Little
Genome-wide methylation is modified by caloric restriction in Daphnia magna. BMC genomics 20 (1) (2019)
Jack Hearn, Franklin Wang-Ngai Chow, Harriet Barton, Matthew Tung, Philip J Wilson, Mark Blaxter, Amy Buck, Tom J Little
Daphnia magna microRNAs respond to nutritional stress and ageing but are not transgenerational. Molecular ecology 27 (6) (2018)