Jae-Hyuck Shim

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 34

Top Venues

Human gene therapy

Proceedings of the National Academy of Sciences of the United States of America

Nature communications

bioRxiv : the preprint server for biology

University of Massachusetts Medical School

Yale University School of Medicine (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Massachusetts Medical School Jul 01 2016

United States

Associate professor :: Medicine

Joan and Sanford I Weill Medical College of Cornell University Sep 02 2012 - Jun 30 2016

United States

Assistant professor :: Pathology

Harvard School of Public Health Apr 01 2010 - Aug 30 2012

United States

Research Scientist/Instructor :: Immunology and Infectious Diseases

Harvard School of Public Health Nov 01 2006 - Mar 31 2010

United States

Postdoctoral Fellow :: Immunology and Infectious Diseases

Education History

Yale University School of Medicine Sep 01 2000 - May 28 2006

United States

PHD :: Immunobiology

Yonsei University Mar 02 1996 - Aug 28 1998

South Korea

MSC :: Biotechnology

Yonsei University Mar 02 1992 - Feb 28 1996

South Korea

BSC :: Biotechnology

Publications

Afreen Anwar, Solimar Ramis De Ayreflor Reyes, Aijaz Ahmad John, Erik Breiling, Abigail M O'Connor, Stephanie Reis, Jae-Hyuck Shim, Ali Asghar Shah, Jagan Srinivasan, Natalie G Farny
Nucleic Acid Aptamers Protect Against Lead (Pb(II)) Toxicity. bioRxiv : the preprint server for biology (2024)
Tadatoshi Sato, Sachin Chaugule, Matthew B Greenblatt, Guangping Gao, Jae-Hyuck Shim
Advances in Bone-Targeting Drug Delivery: Emerging Strategies Using Adeno-Associated Virus. Human gene therapy 35 (9-10) (2024)
Chujiao Lin, Matthew B Greenblatt, Guangping Gao, Jae-Hyuck Shim
Development of AAV-Mediated Gene Therapy Approaches to Treat Skeletal Diseases. Human gene therapy 35 (9-10) (2024)
Chujiao Lin, Matthew B Greenblatt, Guangping Gao, Jae-Hyuck Shim
Development of AAV-Mediated Gene Therapy Approaches to Treat Skeletal Diseases. Human gene therapy 35 (9-10) (2024)
Tadatoshi Sato, Sachin Chaugule, Matthew B Greenblatt, Guangping Gao, Jae-Hyuck Shim
Advances in Bone-Targeting Drug Delivery: Emerging Strategies Using Adeno-Associated Virus. Human gene therapy (2024)
Tadatoshi Sato, Sachin Chaugule, Matthew B Greenblatt, Guangping Gao, Jae-Hyuck Shim
Advances in Bone-Targeting Drug Delivery: Emerging Strategies Using Adeno-Associated Virus. Human gene therapy 35 (9-10) (2024)
Afreen Anwar, Solimar Ramis De Ayreflor Reyes, Aijaz Ahmad John, Erik Breiling, Abigail M O'Connor, Stephanie Reis, Jae-Hyuck Shim, Ali Asghar Shah, Jagan Srinivasan, Natalie G Farny
Nucleic Acid Aptamers Protect Against Lead (Pb(II)) Toxicity. bioRxiv : the preprint server for biology (2024)
Chujiao Lin, Matthew B Greenblatt, Guangping Gao, Jae-Hyuck Shim
Development of AAV-Mediated Gene Therapy Approaches to Treat Skeletal Diseases. Human gene therapy (2024)
Afreen Anwar, Solimar Ramis De Ayreflor Reyes, Aijaz Ahmad John, Erik Breiling, Abigail M O'Connor, Stephanie Reis, Jae-Hyuck Shim, Ali Asghar Shah, Jagan Srinivasan, Natalie G Farny
Nucleic Acid Aptamers Protect Against Lead (Pb(II)) Toxicity. bioRxiv : the preprint server for biology (2024)
Chujiao Lin, Matthew B Greenblatt, Guangping Gao, Jae-Hyuck Shim
Development of AAV-Mediated Gene Therapy Approaches to Treat Skeletal Diseases. Human gene therapy 35 (9-10) (2024)
Tadatoshi Sato, Sachin Chaugule, Matthew B Greenblatt, Guangping Gao, Jae-Hyuck Shim
Advances in Bone-Targeting Drug Delivery: Emerging Strategies Using Adeno-Associated Virus. Human gene therapy 35 (9-10) (2024)
Zheni Stavre, Jung-Min Kim, Yeon-Suk Yang, Kerstin Nündel, Sachin Chaugule, Tadatoshi Sato, Kwang Hwan Park, Guangping Gao, Ellen M Gravallese, Jae-Hyuck Shim
Schnurri-3 inhibition suppresses bone and joint damage in models of rheumatoid arthritis. Proceedings of the National Academy of Sciences of the United States of America 120 (19) (2023)
Zheni Stavre, Jung-Min Kim, Yeon-Suk Yang, Kerstin Nündel, Sachin Chaugule, Tadatoshi Sato, Kwang Hwan Park, Guangping Gao, Ellen M Gravallese, Jae-Hyuck Shim
Schnurri-3 inhibition suppresses bone and joint damage in models of rheumatoid arthritis. Proceedings of the National Academy of Sciences of the United States of America 120 (19) (2023)
Zheni Stavre, Jung-Min Kim, Yeon-Suk Yang, Kerstin Nündel, Sachin Chaugule, Tadatoshi Sato, Kwang Hwan Park, Guangping Gao, Ellen M Gravallese, Jae-Hyuck Shim
Schnurri-3 inhibition suppresses bone and joint damage in models of rheumatoid arthritis. Proceedings of the National Academy of Sciences of the United States of America 120 (19) (2023)
Zheni Stavre, Jung-Min Kim, Yeon-Suk Yang, Kerstin Nündel, Sachin Chaugule, Tadatoshi Sato, Kwang Hwan Park, Guangping Gao, Ellen M Gravallese, Jae-Hyuck Shim
Schnurri-3 inhibition suppresses bone and joint damage in models of rheumatoid arthritis. Proceedings of the National Academy of Sciences of the United States of America 120 (19) (2023)
Zheni Stavre, Jung-Min Kim, Yeon-Suk Yang, Kerstin Nündel, Sachin Chaugule, Tadatoshi Sato, Kwang Hwan Park, Guangping Gao, Ellen M Gravallese, Jae-Hyuck Shim
Schnurri-3 inhibition suppresses bone and joint damage in models of rheumatoid arthritis. Proceedings of the National Academy of Sciences of the United States of America 120 (19) (2023)
Zheni Stavre, Jung-Min Kim, Yeon-Suk Yang, Kerstin Nündel, Sachin Chaugule, Tadatoshi Sato, Kwang Hwan Park, Guangping Gao, Ellen M Gravallese, Jae-Hyuck Shim
Schnurri-3 inhibition suppresses bone and joint damage in models of rheumatoid arthritis. Proceedings of the National Academy of Sciences of the United States of America 120 (19) (2023)
Yeon-Suk Yang, Chujiao Lin, Hong Ma, Jun Xie, Frederick S Kaplan, Guangping Gao, Jae-Hyuck Shim
AAV-Mediated Targeting of the Activin A-ACVR1 R206H Signaling in Fibrodysplasia Ossificans Progressiva. Biomolecules 13 (9) (2023)
Zheni Stavre, Jung-Min Kim, Yeon-Suk Yang, Kerstin Nündel, Sachin Chaugule, Tadatoshi Sato, Kwang Hwan Park, Guangping Gao, Ellen M Gravallese, Jae-Hyuck Shim
Schnurri-3 inhibition suppresses bone and joint damage in models of rheumatoid arthritis. Proceedings of the National Academy of Sciences of the United States of America 120 (19) (2023)
Zheni Stavre, Jung-Min Kim, Yeon-Suk Yang, Kerstin Nündel, Sachin Chaugule, Tadatoshi Sato, Kwang Hwan Park, Guangping Gao, Ellen M Gravallese, Jae-Hyuck Shim
Schnurri-3 inhibition suppresses bone and joint damage in models of rheumatoid arthritis. Proceedings of the National Academy of Sciences of the United States of America 120 (19) (2023)
Jung-Min Kim, Yeon-Suk Yang, Jaehyoung Hong, Sachin Chaugule, Hyonho Chun, Marjolein C H van der Meulen, Ren Xu, Matthew B Greenblatt, Jae-Hyuck Shim
Biphasic regulation of osteoblast development via the ERK MAPK-mTOR pathway. eLife 11 (2022)
Chujiao Lin, Qiyuan Yang, Dongsheng Guo, Jun Xie, Yeon-Suk Yang, Sachin Chaugule, Ngoc DeSouza, Won-Taek Oh, Rui Li, Zhihao Chen, Aijaz A John, Qiang Qiu, Julie Lihua Zhu, Matthew B Greenblatt, Sankar Ghosh, Shaoguang Li, Guangping Gao, Cole M Haynes, Charles P Emerson, Jae-Hyuck Shim
Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration. Nature communications 13 (1) (2022)
Jung-Min Kim, Yeon-Suk Yang, Jun Xie, Oksun Lee, JiHea Kim, Jaehyoung Hong, Brigitte Boldyreff, Odile Filhol-Cochet, Hyonho Chun, Matthew B Greenblatt, Guangping Gao, Jae-Hyuck Shim
Regulation of sclerostin by the SIRT1 stabilization pathway in osteocytes. Cell death and differentiation 29 (8) (2022)
Elisabeth M W Eekhoff, Ruben D de Ruiter, Bernard J Smilde, Ton Schoenmaker, Teun J de Vries, Coen Netelenbos, Edward C Hsiao, Christiaan Scott, Nobuhiko Haga, Zvi Grunwald, Carmen L De Cunto, Maja di Rocco, Patricia L R Delai, Robert J Diecidue, Vrisha Madhuri, Tae-Joon Cho, Rolf Morhart, Clive S Friedman, Michael Zasloff, Gerard Pals, Jae-Hyuck Shim, Guangping Gao, Frederick Kaplan, Robert J Pignolo, Dimitra Micha
Gene Therapy for Fibrodysplasia Ossificans Progressiva: Feasibility and Obstacles. Human gene therapy 33 (15-16) (2022)
Yeon-Suk Yang, Jung-Min Kim, Jun Xie, Sachin Chaugule, Chujiao Lin, Hong Ma, Edward C Hsiao, Jaehyoung Hong, Hyonho Chun, Eileen M Shore, Frederick S Kaplan, Guangping Gao, Jae-Hyuck Shim
Suppression of heterotopic ossification in fibrodysplasia ossificans progressiva using AAV gene delivery. Nature communications 13 (1) (2022)
Sachin Chaugule, Jung-Min Kim, Yeon-Suk Yang, Klaus-Peter Knobeloch, Xi He, Jae-Hyuck Shim
Deubiquitinating Enzyme USP8 Is Essential for Skeletogenesis by Regulating Wnt Signaling. International journal of molecular sciences 22 (19) (2021)
Jun Sun, Dong Yeon Shin, Mark Eiseman, Alisha R Yallowitz, Na Li, Sarfaraz Lalani, Zan Li, Michelle Cung, Seoyeon Bok, Shawon Debnath, Sofia Jenia Marquez, Tommy E White, Abdul G Khan, Ivo C Lorenz, Jae-Hyuck Shim, Francis S Lee, Ren Xu, Matthew B Greenblatt
SLITRK5 is a negative regulator of hedgehog signaling in osteoblasts. Nature communications 12 (1) (2021)
Yongkuk Park, Eugene Cheong, Jun-Goo Kwak, Ryan Carpenter, Jae-Hyuck Shim, Jungwoo Lee
Trabecular bone organoid model for studying the regulation of localized bone remodeling. Science advances 7 (4) (2021)
Jung-Min Kim, Chujiao Lin, Zheni Stavre, Matthew B Greenblatt, Jae-Hyuck Shim
Osteoblast-Osteoclast Communication and Bone Homeostasis. Cells 9 (9) (2020)
Jung-Min Kim, Yeon-Suk Yang, Kwang Hwan Park, Xianpeng Ge, Ren Xu, Na Li, Minkyung Song, Hyunho Chun, Seoyeon Bok, Julia Forgan-Farnam Charles, Odile Filhol-Cochet, Brigitte Boldyreff, Teresa Dinter, Paul B Yu, Ning Kon, Wei Gu, Takeshi Takarada, Matthew B Greenblatt, Jae-Hyuck Shim
A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation. Nature communications 11 (1) (2020)
Seoyeon Bok, Dong Yeon Shin, Alisha R Yallowitz, Mark Eiseman, Michelle Cung, Ren Xu, Na Li, Jun Sun, Alfred L Williams, John E Scott, Bing Su, Jae-Hyuck Shim, Matthew B Greenblatt
MEKK2 mediates aberrant ERK activation in neurofibromatosis type I. Nature communications 11 (1) (2020)
Jung-Min Kim, Yeon-Suk Yang, Kwang Hwan Park, Hwanhee Oh, Matthew B Greenblatt, Jae-Hyuck Shim
The ERK MAPK Pathway Is Essential for Skeletal Development and Homeostasis. International journal of molecular sciences 20 (8) (2019)
Ren Xu, Alisha Yallowitz, An Qin, Zhuhao Wu, Dong Yeon Shin, Jung-Min Kim, Shawon Debnath, Gang Ji, Mathias P Bostrom, Xu Yang, Chao Zhang, Han Dong, Pouneh Kermani, Sarfaraz Lalani, Na Li, Yifang Liu, Michael G Poulos, Amanda Wach, Yi Zhang, Kazuki Inoue, Annarita Di Lorenzo, Baohong Zhao, Jason M Butler, Jae-Hyuck Shim, Laurie H Glimcher, Matthew B Greenblatt
Targeting skeletal endothelium to ameliorate bone loss. Nature medicine 24 (6) (2018)
Jae-Hyuck Shim, Zheni Stavre, Ellen M Gravallese
Bone Loss in Rheumatoid Arthritis: Basic Mechanisms and Clinical Implications. Calcified tissue international 102 (5) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Jae-Hyuck Shim