Jun Xie

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 26

Top Venues

Nature communications

EMBO molecular medicine

Human gene therapy

bioRxiv : the preprint server for biology

University of Massachusetts Medical School

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Massachusetts Medical School

United States

Assistant Professor :: Horae Gene Therapy Center

Publications

Qing Xie, Xiupeng Chen, Hong Ma, Yunxiang Zhu, Yijie Ma, Leila Jalinous, Gerald F Cox, Fiona Weaver, Jun Yang, Zachary Kennedy, Alisha Gruntman, Ailing Du, Qin Su, Ran He, Phillip W L Tai, Guangping Gao, Jun Xie
Improved gene therapy for spinal muscular atrophy in mice using codon-optimized hSMN1 transgene and hSMN1 gene-derived promotor. EMBO molecular medicine 16 (4) (2024)
Nathan Bamidele, Han Zhang, Xiaolong Dong, Haoyang Cheng, Nicholas Gaston, Hailey Feinzig, Hanbing Cao, Karen Kelly, Jonathan K Watts, Jun Xie, Guangping Gao, Erik J Sontheimer
Domain-inlaid Nme2Cas9 adenine base editors with improved activity and targeting scope. Nature communications 15 (1) (2024)
Shun-Qing Liang, Andrew W Navia, Michelle Ramseier, Xuntao Zhou, Michele Martinez, Charles Lee, Chen Zhou, Joae Wu, Jun Xie, Qin Su, Dan Wang, Terence R Flotte, Daniel G Anderson, Alice F Tarantal, Alex K Shalek, Guangping Gao, Shun-Qing Liang
AAV5 Delivery of CRISPR/Cas9 Mediates Genome Editing in the Lungs of Young Rhesus Monkeys. Human gene therapy (2024)
Nathan Bamidele, Han Zhang, Xiaolong Dong, Haoyang Cheng, Nicholas Gaston, Hailey Feinzig, Hanbing Cao, Karen Kelly, Jonathan K Watts, Jun Xie, Guangping Gao, Erik J Sontheimer
Domain-inlaid Nme2Cas9 adenine base editors with improved activity and targeting scope. Nature communications 15 (1) (2024)
Qing Xie, Xiupeng Chen, Hong Ma, Yunxiang Zhu, Yijie Ma, Leila Jalinous, Gerald F Cox, Fiona Weaver, Jun Yang, Zachary Kennedy, Alisha Gruntman, Ailing Du, Qin Su, Ran He, Phillip W L Tai, Guangping Gao, Jun Xie
Improved gene therapy for spinal muscular atrophy in mice using codon-optimized hSMN1 transgene and hSMN1 gene-derived promotor. EMBO molecular medicine 16 (4) (2024)
Shun-Qing Liang, Andrew W Navia, Michelle Ramseier, Xuntao Zhou, Michele Martinez, Charles Lee, Chen Zhou, Joae Wu, Jun Xie, Qin Su, Dan Wang, Terence R Flotte, Daniel G Anderson, Alice F Tarantal, Alex K Shalek, Guangping Gao, Shun-Qing Liang
AAV5 Delivery of CRISPR/Cas9 Mediates Genome Editing in the Lungs of Young Rhesus Monkeys. Human gene therapy (2024)
Qing Xie, Xiupeng Chen, Hong Ma, Yunxiang Zhu, Yijie Ma, Leila Jalinous, Gerald F Cox, Fiona Weaver, Jun Yang, Zachary Kennedy, Alisha Gruntman, Ailing Du, Qin Su, Ran He, Phillip W L Tai, Guangping Gao, Jun Xie
Improved gene therapy for spinal muscular atrophy in mice using codon-optimized hSMN1 transgene and hSMN1 gene-derived promotor. EMBO molecular medicine 16 (4) (2024)
Qing Xie, Xiupeng Chen, Hong Ma, Yunxiang Zhu, Yijie Ma, Leila Jalinous, Gerald F Cox, Fiona Weaver, Jun Yang, Zachary Kennedy, Alisha Gruntman, Ailing Du, Qin Su, Ran He, Phillip W L Tai, Guangping Gao, Jun Xie
Improved gene therapy for spinal muscular atrophy in mice using codon-optimized hSMN1 transgene and hSMN1 gene-derived promotor. EMBO molecular medicine (2024)
Qing Xie, Xiupeng Chen, Hong Ma, Yunxiang Zhu, Yijie Ma, Leila Jalinous, Gerald F Cox, Fiona Weaver, Jun Yang, Zachary Kennedy, Alisha Gruntman, Ailing Du, Qin Su, Ran He, Phillip W L Tai, Guangping Gao, Jun Xie
Improved gene therapy for spinal muscular atrophy in mice using codon-optimized hSMN1 transgene and hSMN1 gene-derived promotor. EMBO molecular medicine 16 (4) (2024)
Nathan Bamidele, Han Zhang, Xiaolong Dong, Haoyang Cheng, Nicholas Gaston, Hailey Feinzig, Hanbing Cao, Karen Kelly, Jonathan K Watts, Jun Xie, Guangping Gao, Erik J Sontheimer
Domain-inlaid Nme2Cas9 adenine base editors with improved activity and targeting scope. Nature communications 15 (1) (2024)
Nathan Bamidele, Han Zhang, Xiaolong Dong, Haoyang Cheng, Nicholas Gaston, Hailey Feinzig, Hanbing Cao, Karen Kelly, Jonathan K Watts, Jun Xie, Guangping Gao, Erik J Sontheimer
Domain-inlaid Nme2Cas9 adenine base editors with improved activity and targeting scope. Nature communications 15 (1) (2024)
Shun-Qing Liang, Andrew W Navia, Michelle Ramseier, Xuntao Zhou, Michele Martinez, Charles Lee, Chen Zhou, Joae Wu, Jun Xie, Qin Su, Dan Wang, Terence R Flotte, Daniel G Anderson, Alice F Tarantal, Alex K Shalek, Guangping Gao, Shun-Qing Liang
AAV5 Delivery of CRISPR/Cas9 Mediates Genome Editing in the Lungs of Young Rhesus Monkeys. Human gene therapy (2024)
Han Zhang, Karen Kelly, Jonathan Lee, Dimas Echeverria Moreno, David A Cooper, Rebecca Panwala, Zexiang Chen, Nicholas Gaston, Gregory A Newby, Jun Xie, David R Liu, Guangping Gao, Scot A Wolfe, Anastasia Khvorova, Jonathan K Watts, Erik J Sontheimer
Self-delivering CRISPR RNAs for AAV Co-delivery and Genome Editing in vivo . bioRxiv : the preprint server for biology (2023)
Mandana Arbab, Zaneta Matuszek, Kaitlyn M Kray, Ailing Du, Gregory A Newby, Anton J Blatnik, Aditya Raguram, Michelle F Richter, Kevin Tianmeng Zhao, Jonathan M Levy, Max W Shen, William David Arnold, Dan Wang, Jun Xie, Guangping Gao, Arthur H M Burghes, David R Liu
Base editing rescue of spinal muscular atrophy in cells and in mice. Science (New York, N.Y.) (2023)
Han Zhang, Karen Kelly, Jonathan Lee, Dimas Echeverria Moreno, David Cooper, Rebecca Panwala, Nadia Amrani, Zexiang Chen, Nicholas Gaston, Atish Wagh, Gregory A Newby, Jun Xie, David R Liu, Guangping Gao, Scot A Wolfe, Anastasia Khvorova, Jonathan K Watts, Erik J Sontheimer
Self-delivering, chemically modified CRISPR RNAs for AAV co-delivery and genome editing in vivo. Nucleic acids research (2023)
Nathan Bamidele, Han Zhang, Xiaolong Dong, Nicholas Gaston, Haoyang Cheng, Karen Kelly, Jonathan K Watts, Jun Xie, Guangping Gao, Erik J Sontheimer
Engineering Nme2Cas9 Adenine Base Editors with Improved Activity and Targeting Scope. bioRxiv : the preprint server for biology (2023)
Nathan Bamidele, Han Zhang, Xiaolong Dong, Nicholas Gaston, Haoyang Cheng, Karen Kelly, Jonathan K Watts, Jun Xie, Guangping Gao, Erik J Sontheimer
Engineering Nme2Cas9 Adenine Base Editors with Improved Activity and Targeting Scope. bioRxiv : the preprint server for biology (2023)
Chujiao Lin, Qiyuan Yang, Dongsheng Guo, Jun Xie, Yeon-Suk Yang, Sachin Chaugule, Ngoc DeSouza, Won-Taek Oh, Rui Li, Zhihao Chen, Aijaz A John, Qiang Qiu, Julie Lihua Zhu, Matthew B Greenblatt, Sankar Ghosh, Shaoguang Li, Guangping Gao, Cole M Haynes, Charles P Emerson, Jae-Hyuck Shim
Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration. Nature communications 13 (1) (2022)
Suk Namkung, Ngoc Tam Tran, Sangeetha Manokaran, Ran He, Qin Su, Jun Xie, Guangping Gao, Phillip W L Tai
Direct ITR-to-ITR Nanopore Sequencing of AAV Vector Genomes. Human gene therapy 33 (21-22) (2022)
Yeon-Suk Yang, Jung-Min Kim, Jun Xie, Sachin Chaugule, Chujiao Lin, Hong Ma, Edward C Hsiao, Jaehyoung Hong, Hyonho Chun, Eileen M Shore, Frederick S Kaplan, Guangping Gao, Jae-Hyuck Shim
Suppression of heterotopic ossification in fibrodysplasia ossificans progressiva using AAV gene delivery. Nature communications 13 (1) (2022)
Shun-Yun Cheng, Yongwen Luo, Anneliese Malachi, Jihye Ko, Qin Su, Jun Xie, Bo Tian, Haijiang Lin, Xiao Ke, Qiang Zheng, Phillip W L Tai, Guangping Gao, Claudio Punzo
Low-Dose Recombinant Adeno-Associated Virus-Mediated Inhibition of Vascular Endothelial Growth Factor Can Treat Neovascular Pathologies Without Inducing Retinal Vasculitis. Human gene therapy 32 (13-14) (2022)
Matthew T N Yarnall, Eleonora I Ioannidi, Cian Schmitt-Ulms, Rohan N Krajeski, Justin Lim, Lukas Villiger, Wenyuan Zhou, Kaiyi Jiang, Sofya K Garushyants, Nathaniel Roberts, Liyang Zhang, Christopher A Vakulskas, John A Walker, Anastasia P Kadina, Adrianna E Zepeda, Kevin Holden, Hong Ma, Jun Xie, Guangping Gao, Lander Foquet, Greg Bial, Sara K Donnelly, Yoshinari Miyata, Daniel R Radiloff, Jordana M Henderson, Andrew Ujita, Omar O Abudayyeh, Jonathan Samuel Gootenberg
Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases. Nature biotechnology (2022)
Jiaming Wang, Yue Zhang, Craig A Mendonca, Onur Yukselen, Khaja Muneeruddin, Lingzhi Ren, Jialing Liang, Chen Zhou, Jun Xie, Jia Li, Zhong Jiang, Alper Kucukural, Scott A Shaffer, Guangping Gao, Dan Wang
AAV-delivered suppressor tRNA overcomes a nonsense mutation in mice. Nature 604 (7905) (2022)
Carlos Lopez-Gomez, Maria J Sanchez-Quintero, Eung Jeon Lee, Gulio Kleiner, Saba Tadesse, Jun Xie, Hasan Orhan Akman, Guangping Gao, Michio Hirano
Synergistic Deoxynucleoside and Gene Therapies for Thymidine Kinase 2 Deficiency. Annals of neurology 90 (4) (2021)
Wenjian Gan, Xiaoming Dai, Xiangpeng Dai, Jun Xie, Shasha Yin, Junjie Zhu, Chen Wang, Yuchen Liu, Jianping Guo, Min Wang, Jing Liu, Jia Hu, Ryan J Quinton, Neil J Ganem, Pengda Liu, John M Asara, Pier Paolo Pandolfi, Yingzi Yang, Zhigang He, Guangping Gao, Wenyi Wei
LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control. Nature cell biology 22 (2) (2020)
Yeon-Suk Yang, Jun Xie, Dan Wang, Jung-Min Kim, Phillip W L Tai, Ellen Gravallese, Guangping Gao, Jae-Hyuck Shim
Bone-targeting AAV-mediated silencing of Schnurri-3 prevents bone loss in osteoporosis. Nature communications 10 (1) (2019)

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Publication Activity (10 Years)

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Jun Xie