Wei Gu

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 42

Top Topics

Histone Deacetylase

Top Venues

Nature communications

Angewandte Chemie (International ed. in English)

Nature cell biology

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Zhe Wang, Xin Yang, Delin Chen, Yanqing Liu, Zhiming Li, Shoufu Duan, Zhiguo Zhang, Xuejun Jiang, Brent R Stockwell, Wei Gu
GAS41 modulates ferroptosis by anchoring NRF2 on chromatin. Nature communications 15 (1) (2024)
Zhenyi Su, Yanqing Liu, Zhangchuan Xia, Anil K Rustgi, Wei Gu
An unexpected role for the ketogenic diet in triggering tumor metastasis by modulating BACH1-mediated transcription. Science advances 10 (23) (2024)
Svetlana N Samovich, Karolina Mikulska-Ruminska, Haider H Dar, Yulia Y Tyurina, Vladimir A Tyurin, Austin B Souryavong, Alexander A Kapralov, Andrew A Amoscato, Ofer Beharier, S Ananth Karumanchi, Claudette M St Croix, Xin Yang, Theodore R Holman, Andrew P VanDemark, Yoel Sadovsky, Rama K Mallampalli, Sally E Wentzel, Wei Gu, Yuri L Bunimovich, Ivet Bahar, Valerian E Kagan, Hülya Bayır
Strikingly High Activity of 15-Lipoxygenase Towards Di-Polyunsaturated Arachidonoyl/Adrenoyl-Phosphatidylethanolamines Generates Peroxidation Signals of Ferroptotic Cell Death. Angewandte Chemie (International ed. in English) 63 (9) (2024)
Enyong Dai, Xin Chen, Andreas Linkermann, Xuejun Jiang, Rui Kang, Valerian E Kagan, Hülya Bayir, Wan Seok Yang, Ana J Garcia-Saez, Maria S Ioannou, Tobias Janowitz, Qitao Ran, Wei Gu, Boyi Gan, Dmitri V Krysko, Xiao-Feng Zhu, Jiayi Wang, Stefan Krautwald, Shinya Toyokuni, Yangchun Xie, Florian R Greten, Qing Yi, Joel A Schick, Jiao Liu, Dmitry I Gabrilovich, Jin-Bao Liu, Herbert J Zeh, Donna D Zhang, Minghua Yang, Juan Iovanna, Manfred Kopf, Timon Erik Adolph, Jen-Tsan Chi, Changfeng Li, Hidenori Ichijo, Michael Karin, Vijay G Sankaran, Weiping Zou, Lorenzo Galluzzi, Ashley I Bush, Binghui Li, Gerry Melino, Eric H Baehrecke, Michael T Lotze, Daniel J Klionsky, Brent R Stockwell, Guido Kroemer, Daolin Tang
A guideline on the molecular ecosystem regulating ferroptosis. Nature cell biology (2024)
Zhe Wang, Xin Yang, Delin Chen, Yanqing Liu, Zhiming Li, Shoufu Duan, Zhiguo Zhang, Xuejun Jiang, Brent R Stockwell, Wei Gu
GAS41 modulates ferroptosis by anchoring NRF2 on chromatin. Nature communications 15 (1) (2024)
Zhe Wang, Xin Yang, Delin Chen, Yanqing Liu, Zhiming Li, Shoufu Duan, Zhiguo Zhang, Xuejun Jiang, Brent R Stockwell, Wei Gu
GAS41 modulates ferroptosis by anchoring NRF2 on chromatin. Nature communications 15 (1) (2024)
Svetlana N Samovich, Karolina Mikulska-Ruminska, Haider H Dar, Yulia Y Tyurina, Vladimir A Tyurin, Austin B Souryavong, Alexander A Kapralov, Andrew A Amoscato, Ofer Beharier, S Ananth Karumanchi, Claudette M St Croix, Xin Yang, Theodore R Holman, Andrew P VanDemark, Yoel Sadovsky, Rama K Mallampalli, Sally E Wentzel, Wei Gu, Yuri L Bunimovich, Ivet Bahar, Valerian E Kagan, Hülya Bayır
Strikingly High Activity of 15-Lipoxygenase Towards Di-Polyunsaturated Arachidonoyl/Adrenoyl-Phosphatidylethanolamines Generates Peroxidation Signals of Ferroptotic Cell Death. Angewandte Chemie (International ed. in English) 63 (9) (2024)
Enyong Dai, Xin Chen, Andreas Linkermann, Xuejun Jiang, Rui Kang, Valerian E Kagan, Hülya Bayir, Wan Seok Yang, Ana J Garcia-Saez, Maria S Ioannou, Tobias Janowitz, Qitao Ran, Wei Gu, Boyi Gan, Dmitri V Krysko, Xiao-Feng Zhu, Jiayi Wang, Stefan Krautwald, Shinya Toyokuni, Yangchun Xie, Florian R Greten, Qing Yi, Joel A Schick, Jiao Liu, Dmitry I Gabrilovich, Jin-Bao Liu, Herbert J Zeh, Donna D Zhang, Minghua Yang, Juan Iovanna, Manfred Kopf, Timon Erik Adolph, Jen-Tsan Chi, Changfeng Li, Hidenori Ichijo, Michael Karin, Vijay G Sankaran, Weiping Zou, Lorenzo Galluzzi, Ashley I Bush, Binghui Li, Gerry Melino, Eric H Baehrecke, Michael T Lotze, Daniel J Klionsky, Brent R Stockwell, Guido Kroemer, Daolin Tang
A guideline on the molecular ecosystem regulating ferroptosis. Nature cell biology (2024)
Svetlana N Samovich, Karolina Mikulska-Ruminska, Haider H Dar, Yulia Y Tyurina, Vladimir A Tyurin, Austin B Souryavong, Alexander A Kapralov, Andrew A Amoscato, Ofer Beharier, S Ananth Karumanchi, Claudette M St Croix, Xin Yang, Theodore R Holman, Andrew P VanDemark, Yoel Sadovsky, Rama K Mallampalli, Sally E Wentzel, Wei Gu, Yuri L Bunimovich, Ivet Bahar, Valerian E Kagan, Hülya Bayır
Strikingly High Activity of 15-Lipoxygenase Towards Di-Polyunsaturated Arachidonoyl/Adrenoyl-Phosphatidylethanolamines Generates Peroxidation Signals of Ferroptotic Cell Death. Angewandte Chemie (International ed. in English) 63 (9) (2024)
Zhe Wang, Xin Yang, Delin Chen, Yanqing Liu, Zhiming Li, Shoufu Duan, Zhiguo Zhang, Xuejun Jiang, Brent R Stockwell, Wei Gu
GAS41 modulates ferroptosis by anchoring NRF2 on chromatin. Nature communications 15 (1) (2024)
Enyong Dai, Xin Chen, Andreas Linkermann, Xuejun Jiang, Rui Kang, Valerian E Kagan, Hülya Bayir, Wan Seok Yang, Ana J Garcia-Saez, Maria S Ioannou, Tobias Janowitz, Qitao Ran, Wei Gu, Boyi Gan, Dmitri V Krysko, Xiao-Feng Zhu, Jiayi Wang, Stefan Krautwald, Shinya Toyokuni, Yangchun Xie, Florian R Greten, Qing Yi, Joel A Schick, Jiao Liu, Dmitry I Gabrilovich, Jin-Bao Liu, Herbert J Zeh, Donna D Zhang, Minghua Yang, Juan Iovanna, Manfred Kopf, Timon Erik Adolph, Jen-Tsan Chi, Changfeng Li, Hidenori Ichijo, Michael Karin, Vijay G Sankaran, Weiping Zou, Lorenzo Galluzzi, Ashley I Bush, Binghui Li, Gerry Melino, Eric H Baehrecke, Michael T Lotze, Daniel J Klionsky, Brent R Stockwell, Guido Kroemer, Daolin Tang
A guideline on the molecular ecosystem regulating ferroptosis. Nature cell biology (2024)
Svetlana N Samovich, Karolina Mikulska-Ruminska, Haider H Dar, Yulia Y Tyurina, Vladimir A Tyurin, Austin B Souryavong, Alexander A Kapralov, Andrew A Amoscato, Ofer Beharier, S Ananth Karumanchi, Claudette M St Croix, Xin Yang, Theodore R Holman, Andrew P VanDemark, Yoel Sadovsky, Rama K Mallampalli, Sally E Wentzel, Wei Gu, Yuri L Bunimovich, Ivet Bahar, Valerian E Kagan, Hülya Bayır
Strikingly High Activity of 15-Lipoxygenase Towards Di-Polyunsaturated Arachidonoyl/Adrenoyl-Phosphatidylethanolamines Generates Peroxidation Signals of Ferroptotic Cell Death. Angewandte Chemie (International ed. in English) 63 (9) (2024)
Weiwei Cui, Meng Guo, Dong Liu, Peng Xiao, Chuancheng Yang, Haidi Huang, Chunhui Liang, Yinghong Yang, Xiaolong Fu, Yudan Zhang, Jiaxing Liu, Shuang Shi, Jingjing Cong, Zili Han, Yunfei Xu, Chuanxin Wang, Chengqian Yin, Yongchun Zhang, Jinpeng Sun, Wei Gu, Ren-Jie Chai, Shu Zhu, Bo Chu
Gut microbial metabolite facilitates colorectal cancer development via ferroptosis inhibition. Nature cell biology 26 (1) (2024)
Svetlana N Samovich, Karolina Mikulska-Ruminska, Haider H Dar, Yulia Y Tyurina, Vladimir A Tyurin, Austin B Souryavong, Alexander A Kapralov, Andrew A Amoscato, Ofer Beharier, S Ananth Karumanchi, Claudette M St Croix, Xin Yang, Theodore R Holman, Andrew P VanDemark, Yoel Sadovsky, Rama K Mallampalli, Sally E Wentzel, Wei Gu, Yuri L Bunimovich, Ivet Bahar, Valerian E Kagan, Hülya Bayır
Strikingly High Activity of 15-Lipoxygenase Towards Di-Polyunsaturated Arachidonoyl/Adrenoyl-Phosphatidylethanolamines Generates Peroxidation Signals of Ferroptotic Cell Death. Angewandte Chemie (International ed. in English) 63 (9) (2024)
Svetlana N Samovich, Karolina Mikulska-Ruminska, Haider H Dar, Yulia Y Tyurina, Vladimir A Tyurin, Austin B Souryavong, Alexander A Kapralov, Andrew A Amoscato, Ofer Beharier, S Ananth Karumanchi, Claudette M St Croix, Xin Yang, Theodore R Holman, Andrew P VanDemark, Yoel Sadovsky, Rama K Mallampalli, Sally E Wentzel, Wei Gu, Yuri L Bunimovich, Ivet Bahar, Valerian E Kagan, Hülya Bayır
Strikingly High Activity of 15-Lipoxygenase Towards Di-Polyunsaturated Arachidonoyl/Adrenoyl-Phosphatidylethanolamines Generates Peroxidation Signals of Ferroptotic Cell Death. Angewandte Chemie (International ed. in English) 63 (9) (2024)
Svetlana N Samovich, Karolina Mikulska-Ruminska, Haider H Dar, Yulia Y Tyurina, Vladimir A Tyurin, Austin B Souryavong, Alexander A Kapralov, Andrew A Amoscato, Ofer Beharier, S Ananth Karumanchi, Claudette M St Croix, Xin Yang, Theodore R Holman, Andrew P VanDemark, Yoel Sadovsky, Rama K Mallampalli, Sally E Wentzel, Wei Gu, Yuri L Bunimovich, Ivet Bahar, Valerian E Kagan, Hülya Bayır
Strikingly High Activity of 15-Lipoxygenase Towards Di-Polyunsaturated Arachidonoyl/Adrenoyl-Phosphatidylethanolamines Generates Peroxidation Signals of Ferroptotic Cell Death. Angewandte Chemie (International ed. in English) (2024)
Weiwei Cui, Meng Guo, Dong Liu, Peng Xiao, Chuancheng Yang, Haidi Huang, Chunhui Liang, Yinghong Yang, Xiaolong Fu, Yudan Zhang, Jiaxing Liu, Shuang Shi, Jingjing Cong, Zili Han, Yunfei Xu, Chuanxin Wang, Chengqian Yin, Yongchun Zhang, Jinpeng Sun, Wei Gu, Ren-Jie Chai, Shu Zhu, Bo Chu
Gut microbial metabolite facilitates colorectal cancer development via ferroptosis inhibition. Nature cell biology 26 (1) (2024)
Svetlana N Samovich, Karolina Mikulska-Ruminska, Haider H Dar, Yulia Y Tyurina, Vladimir A Tyurin, Austin B Souryavong, Alexander A Kapralov, Andrew A Amoscato, Ofer Beharier, S Ananth Karumanchi, Claudette M St Croix, Xin Yang, Theodore R Holman, Andrew P VanDemark, Yoel Sadovsky, Rama K Mallampalli, Sally E Wentzel, Wei Gu, Yuri L Bunimovich, Ivet Bahar, Valerian E Kagan, Hülya Bayır
Strikingly High Activity of 15-Lipoxygenase Towards Di-Polyunsaturated Arachidonoyl/Adrenoyl-Phosphatidylethanolamines Generates Peroxidation Signals of Ferroptotic Cell Death. Angewandte Chemie (International ed. in English) 63 (9) (2024)
Zhe Wang, Xin Yang, Delin Chen, Yanqing Liu, Zhiming Li, Shoufu Duan, Zhiguo Zhang, Xuejun Jiang, Brent R Stockwell, Wei Gu
GAS41 modulates ferroptosis by anchoring NRF2 on chromatin. Nature communications 15 (1) (2024)
Zhenyi Su, Yanqing Liu, Zhangchuan Xia, Anil K Rustgi, Wei Gu
An unexpected role for the ketogenic diet in triggering tumor metastasis by modulating BACH1-mediated transcription. Science advances 10 (23) (2024)
Svetlana N Samovich, Karolina Mikulska-Ruminska, Haider H Dar, Yulia Y Tyurina, Vladimir A Tyurin, Austin B Souryavong, Alexander A Kapralov, Andrew A Amoscato, Ofer Beharier, S Ananth Karumanchi, Claudette M St Croix, Xin Yang, Theodore R Holman, Andrew P VanDemark, Yoel Sadovsky, Rama K Mallampalli, Sally E Wentzel, Wei Gu, Yuri L Bunimovich, Ivet Bahar, Valerian E Kagan, Hülya Bayır
Strikingly High Activity of 15-Lipoxygenase Towards Di-Polyunsaturated Arachidonoyl/Adrenoyl-Phosphatidylethanolamines Generates Peroxidation Signals of Ferroptotic Cell Death. Angewandte Chemie (International ed. in English) 63 (9) (2024)
Zhe Wang, Xin Yang, Delin Chen, Yanqing Liu, Zhiming Li, Shoufu Duan, Zhiguo Zhang, Xuejun Jiang, Brent R Stockwell, Wei Gu
GAS41 modulates ferroptosis by anchoring NRF2 on chromatin. Nature communications 15 (1) (2024)
Weiwei Cui, Meng Guo, Dong Liu, Peng Xiao, Chuancheng Yang, Haidi Huang, Chunhui Liang, Yinghong Yang, Xiaolong Fu, Yudan Zhang, Jiaxing Liu, Shuang Shi, Jingjing Cong, Zili Han, Yunfei Xu, Chuanxin Wang, Chengqian Yin, Yongchun Zhang, Jinpeng Sun, Wei Gu, Ren-Jie Chai, Shu Zhu, Bo Chu
Gut microbial metabolite facilitates colorectal cancer development via ferroptosis inhibition. Nature cell biology (2024)
Zhenyi Su, Yanqing Liu, Zhangchuan Xia, Anil K Rustgi, Wei Gu
An unexpected role for the ketogenic diet in triggering tumor metastasis by modulating BACH1-mediated transcription. Science advances 10 (23) (2024)
Weiwei Cui, Meng Guo, Dong Liu, Peng Xiao, Chuancheng Yang, Haidi Huang, Chunhui Liang, Yinghong Yang, Xiaolong Fu, Yudan Zhang, Jiaxing Liu, Shuang Shi, Jingjing Cong, Zili Han, Yunfei Xu, Chuanxin Wang, Chengqian Yin, Yongchun Zhang, Jinpeng Sun, Wei Gu, Ren-Jie Chai, Shu Zhu, Bo Chu
Gut microbial metabolite facilitates colorectal cancer development via ferroptosis inhibition. Nature cell biology 26 (1) (2024)
Zhe Wang, Xin Yang, Delin Chen, Yanqing Liu, Zhiming Li, Shoufu Duan, Zhiguo Zhang, Xuejun Jiang, Brent R Stockwell, Wei Gu
GAS41 modulates ferroptosis by anchoring NRF2 on chromatin. Nature communications 15 (1) (2024)
Zhenyi Su, Ning Kon, Jingjie Yi, Haiqing Zhao, Wanwei Zhang, Qiaosi Tang, Huan Li, Hiroki Kobayashi, Zhiming Li, Shou-Fu Duan, Yanqing Liu, Kenneth P Olive, Zhiguo Zhang, Barry Honig, James J Manfredi, Anil K Rustgi, Wei Gu
Specific regulation of BACH1 by the hotspot mutant p53 R175H reveals a distinct gain-of-function mechanism. Nature cancer (2023)
Jingjie Yi, Huan Li, Bo Chu, Ning Kon, Xiaoping Hu, Jianping Hu, Yan Xiong, H Umit Kaniskan, Jian Jin, Wei Gu
Inhibition of USP7 induces p53-independent tumor growth suppression in triple-negative breast cancers by destabilizing FOXM1. Cell death and differentiation (2023)
Jingjie Yi, Omid Tavana, Huan Li, Donglai Wang, Richard J Baer, Wei Gu
Targeting USP2 regulation of VPRBP-mediated degradation of p53 and PD-L1 for cancer therapy. Nature communications 14 (1) (2023)
Yanqing Liu, Wei Gu
p53 in ferroptosis regulation: the new weapon for the old guardian. Cell death and differentiation 29 (5) (2022)
Yan Mo, Shou-Fu Duan, Xu Zhang, Xu Hua, Hui Zhou, Hong-Jian Wei, Jun Watanabe, Nicholas McQuillan, Zhenyi Su, Wei Gu, Cheng-Chia Wu, Christopher R Vakoc, Rintaro Hashizume, Kenneth Chang, Zhiguo Zhang
Epigenome Programming by H3.3K27M Mutation Creates a Dependence of Pediatric Glioma on SMARCA4. Cancer discovery 12 (12) (2022)
Zhangchuan Xia, Ning Kon, Alyssa P Gu, Omid Tavana, Wei Gu
Deciphering the acetylation code of p53 in transcription regulation and tumor suppression. Oncogene 41 (22) (2022)
Xin Yang, Xingwu Wang, Zhiming Li, Shoufu Duan, Huan Li, Jian Jin, Zhiguo Zhang, Wei Gu
An unexpected role for Dicer as a reader of the unacetylated DNA binding domain of p53 in transcriptional regulation. Science advances 7 (44) (2021)
Chunjie Meng, Jun Zhan, Delin Chen, Genze Shao, Hongquan Zhang, Wei Gu, Jianyuan Luo
The deubiquitinase USP11 regulates cell proliferation and ferroptotic cell death via stabilization of NRF2 USP11 deubiquitinates and stabilizes NRF2. Oncogene 40 (9) (2021)
Pingzhao Zhang, Kun Gao, Liang Zhang, Huiru Sun, Xiaying Zhao, Yajuan Liu, Zeheng Lv, Qing Shi, Yingji Chen, Dongyue Jiao, Yao Li, Wei Gu, Chenji Wang
CRL2-KLHDC3 E3 ubiquitin ligase complex suppresses ferroptosis through promoting p14ARF degradation. Cell death and differentiation (2021)
Delin Chen, Bo Chu, Xin Yang, Zhaoqi Liu, Ying Jin, Ning Kon, Raúl Rabadán, Xuejun Jiang, Brent R Stockwell, Wei Gu
iPLA2β-mediated lipid detoxification controls p53-driven ferroptosis independent of GPX4. Nature communications 12 (1) (2021)
Zhijie Cao, Ning Kon, Yajing Liu, Wenbin Xu, Jia Wen, Han Yao, Mi Zhang, Zhen Wu, Xiaojun Yan, Wei-Guo Zhu, Wei Gu, Donglai Wang
An unexpected role for p53 in regulating cancer cell-intrinsic PD-1 by acetylation. Science advances 7 (14) (2021)
Jung-Min Kim, Yeon-Suk Yang, Kwang Hwan Park, Xianpeng Ge, Ren Xu, Na Li, Minkyung Song, Hyunho Chun, Seoyeon Bok, Julia Forgan-Farnam Charles, Odile Filhol-Cochet, Brigitte Boldyreff, Teresa Dinter, Paul B Yu, Ning Kon, Wei Gu, Takeshi Takarada, Matthew B Greenblatt, Jae-Hyuck Shim
A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation. Nature communications 11 (1) (2020)
Ya-Fei Lu, Xiao-Peng Xu, Xiao-Peng Lu, Qian Zhu, Ge Liu, Yan-Tao Bao, He Wen, Ying-Lu Li, Wei Gu, Wei-Guo Zhu
SIRT7 activates p53 by enhancing PCAF-mediated MDM2 degradation to arrest the cell cycle. Oncogene 39 (24) (2020)
Michael A Badgley, Daniel M Kremer, Hans Carlo Maurer, Kathleen E DelGiorno, Ho-Joon Lee, Vinee Purohit, Irina R Sagalovskiy, Alice Ma, Jonathan Kapilian, Christina E M Firl, Amanda R Decker, Steve A Sastra, Carmine F Palermo, Leonardo R Andrade, Peter Sajjakulnukit, Li Zhang, Zachary P Tolstyka, Tal Hirschhorn, Candice Lamb, Tong Liu, Wei Gu, E Scott Seeley, Everett Stone, George Georgiou, Uri Manor, Alina Iuga, Geoffrey M Wahl, Brent R Stockwell, Costas Andreas Lyssiotis, Kenneth P Olive
Cysteine depletion induces pancreatic tumor ferroptosis in mice. Science (New York, N.Y.) 368 (6486) (2020)
Xuexian Fang, Hao Wang, Dan Han, Enjun Xie, Xiang Yang, Jiayu Wei, Shanshan Gu, Feng Gao, Nali Zhu, Xiangju Yin, Qi Cheng, Pan Zhang, Wei Dai, Jinghai Chen, Fuquan Yang, Huang-Tian Yang, Andreas Linkermann, Wei Gu, Junxia Min, Fudi Wang
Ferroptosis as a target for protection against cardiomyopathy. Proceedings of the National Academy of Sciences of the United States of America 116 (7) (2019)
Bo Chu, Ning Kon, Delin Chen, Tongyuan Li, Tong Liu, Le Jiang, Shujuan Song, Omid Tavana, Wei Gu
ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway. Nature cell biology 21 (5) (2019)