James P Tam

ResearcherID Scopus Author ID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 30

Top Venues

Angewandte Chemie (International ed. in English)

Bioconjugate chemistry

Journal of the American Chemical Society

The Journal of organic chemistry

Nanyang Technological University

University of Wisconsin (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Nanyang Technological University

Singapore

Director, Synzymes and Natural Products Center (SYNC) :: School of Biological Sciences

Nanyang Technological University

Singapore

Lee Wee Nam Professor :: School of Biological Sciences

Nanyang Technological University

Singapore

Professor, Herbalomics and Drug Discovery Laboratory :: School of Biological Sciences

Nanyang Technological University

Singapore

Director, Double Degree Programme in Biomedical Sciences and Chinese Medicine :: Biochemistry

The Scripps Research Institute

United States

Professor :: Biochemistry

Nanyang Technological University

Singapore

Founding Dean and Director :: School of Biological Sciences

Vanderbilt University

United States

Professor :: Department of Microbiology

The Rockefeller University

United States

Associate Professor :: Biochemistry

The Rockefeller University

United States

Assistant Professor :: Biochemistry

The Rockefeller University

United States

Research Associate :: Biochemistry

The Rockefeller University

United States

Postdoctoral Fellow :: Biochemistry

Education History

University of Wisconsin

United States

PHD :: Medicinal Chemistry

University of Wisconsin Sep 01 1968 - Jun 15 1971

United States

BSC :: Chemistry

Publications

Antony Kam, Shining Loo, Yibo Qiu, Chuan Fa Liu, James P Tam
Ultrafast Biomimetic Oxidative Folding of Cysteine-rich Peptides and Microproteins in Organic Solvents. Angewandte Chemie (International ed. in English) 63 (14) (2024)
Antony Kam, Shining Loo, Yibo Qiu, Chuan Fa Liu, James P Tam
Ultrafast Biomimetic Oxidative Folding of Cysteine-rich Peptides and Microproteins in Organic Solvents. Angewandte Chemie (International ed. in English) (2024)
Antony Kam, Shining Loo, Yibo Qiu, Chuan Fa Liu, James P Tam
Ultrafast Biomimetic Oxidative Folding of Cysteine-rich Peptides and Microproteins in Organic Solvents. Angewandte Chemie (International ed. in English) 63 (14) (2024)
Antony Kam, Shining Loo, Yibo Qiu, Chuan Fa Liu, James P Tam
Ultrafast Biomimetic Oxidative Folding of Cysteine-rich Peptides and Microproteins in Organic Solvents. Angewandte Chemie (International ed. in English) 63 (14) (2024)
James P Tam, Jiayi Huang, Shining Loo, Yimeng Li, Antony Kam
Ginsentide-like Coffeetides Isolated from Coffee Waste Are Cell-Penetrating and Metal-Binding Microproteins. Molecules (Basel, Switzerland) 28 (18) (2023)
Janet To, Xiaohong Zhang, James P Tam
Design of Potent and Salt-Insensitive Antimicrobial Branched Peptides. Polymers 15 (17) (2023)
Yiyin Xia, Fupeng Li, Xiaohong Zhang, Seetharamsing Balamkundu, Fan Tang, Side Hu, Julien Lescar, James P Tam, Chuan Fa Liu
A Cascade Enzymatic Reaction Scheme for Irreversible Transpeptidative Protein Ligation. Journal of the American Chemical Society (2023)
Bamaprasad Dutta, Shining Loo, Antony Kam, Siu Kwan Sze, James P Tam
Ginsentide TP1 Protects Hypoxia-Induced Dysfunction and ER Stress-Linked Apoptosis. Cells 12 (10) (2023)
Xinya Hemu, Ning-Yu Chan, Heng Tai Liew, Side Hu, Xiaohong Zhang, Aida Serra, Julien Lescar, Chuan-Fa Liu, James P Tam
Substrate-binding Glycine Residues are Major Determinants for Hydrolase and Ligase Activity of Plant Legumains. The New phytologist (2023)
Bamaprasad Dutta, Shining Loo, Antony Kam, James P Tam
Plant-derived cell-penetrating microprotein α-astratide aM1 targets Akt signaling and alleviates insulin resistance. Cellular and molecular life sciences : CMLS 80 (10) (2023)
Xinya Hemu, Ning-Yu Chan, Heng Tai Liew, Side Hu, Xiaohong Zhang, Aida Serra, Julien Lescar, Chuan Fa Liu, James P Tam
Substrate-binding glycine residues are major determinants for hydrolase and ligase activity of plant legumains. The New phytologist (2023)
Dingpeng Zhang, Zhen Wang, Side Hu, Ning-Yu Chan, Heng Tai Liew, Julien Lescar, James P Tam, Chuan Fa Liu
Asparaginyl Endopeptidase-Mediated Protein C-Terminal Hydrazinolysis for the Synthesis of Bioconjugates. Bioconjugate chemistry 33 (1) (2022)
Side Hu, Abbas El Sahili, Srujana Kishore, Yee Hwa Wong, Xinya Hemu, Boon Chong Goh, Zhi-Pei Sang, Zhen Wang, James P Tam, Chuan Fa Liu, Julien Lescar
Structural basis for proenzyme maturation, substrate recognition, and ligation by a hyperactive peptide asparaginyl ligase. The Plant cell 34 (12) (2022)
Shining Loo, Antony Kam, Bin Bin Li, Nan Feng, Xiao-Liang Wang, James P Tam
Discovery of Hyperstable Noncanonical Plant-Derived Epidermal Growth Factor Receptor Agonist and Analogs. Journal of medicinal chemistry 64 (11) (2021)
Yiyin Xia, Janet To, Ning-Yu Chan, Side Hu, Heng Tai Liew, Seetharamsing Balamkundu, Xiaohong Zhang, Julien Lescar, Surajit Bhattacharjya, James P Tam, Chuan Fa Liu
Nγ -Hydroxyasparagine: A Multifunctional Unnatural Amino Acid That is a Good P1 Substrate of Asparaginyl Peptide Ligases. Angewandte Chemie (International ed. in English) 60 (41) (2021)
Xinya Hemu, Xiaohong Zhang, Giang K T Nguyen, Janet To, Aida Serra, Shining Loo, Siu Kwan Sze, Chuan Fa Liu, James P Tam
Characterization and application of natural and recombinant butelase-1 to improve industrial enzymes by end-to-end circularization. RSC advances 11 (37) (2021)
Dingpeng Zhang, Zhen Wang, Side Hu, Julien Lescar, James P Tam, Chuan-Fa Liu
Vypal2: A Versatile Peptide Ligase for Precision Tailoring of Proteins. International journal of molecular sciences 23 (1) (2021)
Shining Loo, Stephanie V Tay, Antony Kam, Fan Tang, Jing-Song Fan, Daiwen Yang, James P Tam
Anti-Fungal Hevein-like Peptides Biosynthesized from Quinoa Cleavable Hololectins. Molecules (Basel, Switzerland) 26 (19) (2021)
Dingpeng Zhang, Zhen Wang, Side Hu, Seetharamsing Balamkundu, Janet To, Xiaohong Zhang, Julien Lescar, James P Tam, Chuan Fa Liu
pH-Controlled Protein Orthogonal Ligation Using Asparaginyl Peptide Ligases. Journal of the American Chemical Society 143 (23) (2021)
Xinya Hemu, Janet To, Xiaohong Zhang, James P Tam
Correction to Immobilized Peptide Asparaginyl Ligases Enhance Stability and Facilitate Macrocyclization and Site-Specific Ligation. The Journal of organic chemistry 85 (6) (2020)
Xiaobao Bi, Juan Yin, Dingpeng Zhang, Xiaohong Zhang, Seetharamsing Balamkundu, Julien Lescar, Peter C Dedon, James P Tam, Chuan Fa Liu
Tagging Transferrin Receptor with a Disulfide FRET Probe To Gauge the Redox State in Endosomal Compartments. Analytical chemistry 92 (18) (2020)
Xinya Hemu, Janet To, Xiaohong Zhang, James P Tam
Immobilized Peptide Asparaginyl Ligases Enhance Stability and Facilitate Macrocyclization and Site-Specific Ligation. The Journal of organic chemistry 85 (3) (2020)
Jiayi Huang, Ka H Wong, Stephanie V Tay, Aida Serra, Newman Siu Kwan Sze, James P Tam
Astratides: Insulin-Modulating, Insecticidal, and Antifungal Cysteine-Rich Peptides from Astragalus membranaceus. Journal of natural products 82 (2) (2019)
Xinya Hemu, Xiaohong Zhang, James P Tam
Ligase-Controlled Cyclo-oligomerization of Peptides. Organic letters 21 (7) (2019)
Xinya Hemu, Abbas El Sahili, Side Hu, Kaho Wong, Yu Chen, Yee Hwa Wong, Xiaohong Zhang, Aida Serra, Boon Chong Goh, Dina A Darwis, Ming Wei Chen, Siu Kwan Sze, Chuan-Fa Liu, Julien Lescar, James P Tam
Structural determinants for peptide-bond formation by asparaginyl ligases. Proceedings of the National Academy of Sciences of the United States of America 116 (24) (2019)
Thibault J Harmand, Djenet Bousbaine, Alix I Chan, Xiaohong Zhang, David R Liu, James P Tam, Hidde L Ploegh
One-Pot Dual Labeling of IgG 1 and Preparation of C-to-C Fusion Proteins Through a Combination of Sortase A and Butelase 1. Bioconjugate chemistry 29 (10) (2018)
Geeta Kumari, Ka Ho Wong, Aida Serra, Joon Shin, Ho Sup Yoon, Siu Kwan Sze, James P Tam
Molecular diversity and function of jasmintides from Jasminum sambac. BMC plant biology 18 (1) (2018)
Xiaobao Bi, Juan Yin, Xinya Hemu, Chang Rao, James P Tam, Chuan Fa Liu
Immobilization and Intracellular Delivery of Circular Proteins by Modifying a Genetically Incorporated Unnatural Amino Acid. Bioconjugate chemistry 29 (7) (2018)
Renliang Yang, Yee Hwa Wong, Giang K T Nguyen, James P Tam, Julien Lescar, Bin Wu
Engineering a Catalytically Efficient Recombinant Protein Ligase. Journal of the American Chemical Society 139 (15) (2017)
Yibo Qiu, Misako Taichi, Na Wei, Huan Yang, Kathy Qian Luo, James P Tam
An Orally Active Bradykinin B1 Receptor Antagonist Engineered as a Bifunctional Chimera of Sunflower Trypsin Inhibitor. Journal of medicinal chemistry 60 (1) (2016)
Phuong Quoc Thuc Nguyen, Justin Seng Geap Ooi, Ngan Thi Kim Nguyen, Shujing Wang, Mei Huang, Ding Xiang Liu, James P Tam
Antiviral Cystine Knot α-Amylase Inhibitors from Alstonia scholaris. The Journal of biological chemistry 290 (52) (2015)

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Publication Activity (10 Years)

Top Topics

Top Venues

James P Tam