James Richard Baker (James R Baker, James R Baker)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 38

Top Topics

Human Serum Albumin

Positron Emission Tomography

Top Venues

Bioconjugate chemistry

Chemical science

Journal of the American Chemical Society

Chemical communications (Cambridge, England)

This page only lists publications with an associated author ORCID identifier.

Publications

Anders Dinesen, Veronica L Andersen, Marwa Elkhashab, Diego Pilati, Pernille Bech, Elisabeth Fuchs, Torbjørn R Samuelsen, Alexander Winther, Yunpeng Cai, Anders Märcher, Archie Wall, Marjan Omer, Jesper S Nielsen, Vijay Chudasama, James Richard Baker, Kurt Vesterager Gothelf, Jesper Wengel, Jørgen Kjems, Kenneth A Howard
An Albumin-Holliday Junction Biomolecular Modular Design for Programmable Multifunctionality and Prolonged Circulation. Bioconjugate chemistry 35 (2) (2024)
Anders Dinesen, Veronica L Andersen, Marwa Elkhashab, Diego Pilati, Pernille Bech, Elisabeth Fuchs, Torbjørn R Samuelsen, Alexander Winther, Yunpeng Cai, Anders Märcher, Archie Wall, Marjan Omer, Jesper S Nielsen, Vijay Chudasama, James Richard Baker, Kurt Vesterager Gothelf, Jesper Wengel, Jørgen Kjems, Kenneth A Howard
An Albumin-Holliday Junction Biomolecular Modular Design for Programmable Multifunctionality and Prolonged Circulation. Bioconjugate chemistry (2024)
Anders Dinesen, Veronica L Andersen, Marwa Elkhashab, Diego Pilati, Pernille Bech, Elisabeth Fuchs, Torbjørn R Samuelsen, Alexander Winther, Yunpeng Cai, Anders Märcher, Archie Wall, Marjan Omer, Jesper S Nielsen, Vijay Chudasama, James Richard Baker, Kurt Vesterager Gothelf, Jesper Wengel, Jørgen Kjems, Kenneth A Howard
An Albumin-Holliday Junction Biomolecular Modular Design for Programmable Multifunctionality and Prolonged Circulation. Bioconjugate chemistry 35 (2) (2024)
Anders Dinesen, Veronica L Andersen, Marwa Elkhashab, Diego Pilati, Pernille Bech, Elisabeth Fuchs, Torbjørn R Samuelsen, Alexander Winther, Yunpeng Cai, Anders Märcher, Archie Wall, Marjan Omer, Jesper S Nielsen, Vijay Chudasama, James Richard Baker, Kurt Vesterager Gothelf, Jesper Wengel, Jørgen Kjems, Kenneth A Howard
An Albumin-Holliday Junction Biomolecular Modular Design for Programmable Multifunctionality and Prolonged Circulation. Bioconjugate chemistry 35 (2) (2024)
Anders Dinesen, Veronica L Andersen, Marwa Elkhashab, Diego Pilati, Pernille Bech, Elisabeth Fuchs, Torbjørn R Samuelsen, Alexander Winther, Yunpeng Cai, Anders Märcher, Archie Wall, Marjan Omer, Jesper S Nielsen, Vijay Chudasama, James Richard Baker, Kurt Vesterager Gothelf, Jesper Wengel, Jørgen Kjems, Kenneth A Howard
An Albumin-Holliday Junction Biomolecular Modular Design for Programmable Multifunctionality and Prolonged Circulation. Bioconjugate chemistry 35 (2) (2024)
Steven Y Yap, Tobias Butcher, Richard J Spears, Clíona McMahon, Ioanna A Thanasi, James Richard Baker, Vijay Chudasama
Chemo- and regio-selective differential modification of native cysteines on an antibody via the use of dehydroalanine forming reagents. Chemical science 15 (22) (2024)
Steven Y Yap, Tobias Butcher, Richard J Spears, Clíona McMahon, Ioanna A Thanasi, James Richard Baker, Vijay Chudasama
Chemo- and regio-selective differential modification of native cysteines on an antibody via the use of dehydroalanine forming reagents. Chemical science 15 (22) (2024)
Anders Dinesen, Veronica L Andersen, Marwa Elkhashab, Diego Pilati, Pernille Bech, Elisabeth Fuchs, Torbjørn R Samuelsen, Alexander Winther, Yunpeng Cai, Anders Märcher, Archie Wall, Marjan Omer, Jesper S Nielsen, Vijay Chudasama, James Richard Baker, Kurt Vesterager Gothelf, Jesper Wengel, Jørgen Kjems, Kenneth A Howard
An Albumin-Holliday Junction Biomolecular Modular Design for Programmable Multifunctionality and Prolonged Circulation. Bioconjugate chemistry 35 (2) (2024)
Mikesh Patel, Nafsika Forte, Charlie R Bishop, Michael J Porter, Matthew Dagwell, Kersti Karu, Vijay Chudasama, James Richard Baker
The Nitrile Bis-Thiol Bioconjugation Reaction. Journal of the American Chemical Society 146 (1) (2023)
Fabien Thoreau, Léa N C Rochet, James Richard Baker, Vijay Chudasama
Enabling the formation of native mAb, Fab' and Fc-conjugates using a bis-disulfide bridging reagent to achieve tunable payload-to-antibody ratios (PARs). Chemical science 14 (14) (2023)
Mikesh Patel, Nafsika Forte, Charlie R Bishop, Michael J Porter, Matthew Dagwell, Kersti Karu, Vijay Chudasama, James Richard Baker
The Nitrile Bis-Thiol Bioconjugation Reaction. Journal of the American Chemical Society 146 (1) (2023)
Mikesh Patel, Nafsika Forte, Charlie R Bishop, Michael J Porter, Matthew Dagwell, Kersti Karu, Vijay Chudasama, James Richard Baker
The Nitrile Bis-Thiol Bioconjugation Reaction. Journal of the American Chemical Society (2023)
Fabien Thoreau, Peter A Szijj, Michelle K Greene, Léa N C Rochet, Ioanna A Thanasi, Jaine K Blayney, Antoine Maruani, James Richard Baker, Christopher J Scott, Vijay Chudasama
Modular Chemical Construction of IgG-like Mono- and Bispecific Synthetic Antibodies (SynAbs). ACS central science 9 (3) (2023)
Mikesh Patel, Nafsika Forte, Charlie R Bishop, Michael J Porter, Matthew Dagwell, Kersti Karu, Vijay Chudasama, James Richard Baker
The Nitrile Bis-Thiol Bioconjugation Reaction. Journal of the American Chemical Society 146 (1) (2023)
Fabien Thoreau, Peter A Szijj, Michelle K Greene, Léa N C Rochet, Ioanna A Thanasi, Jaine K Blayney, Antoine Maruani, James Richard Baker, Christopher J Scott, Vijay Chudasama
Modular Chemical Construction of IgG-like Mono- and Bispecific Synthetic Antibodies (SynAbs). ACS central science 9 (3) (2023)
Yanbo Zhao, Vijay Chudasama, James Richard Baker
Trifunctional Dibromomaleimide Reagents Built Around A Lysine Scaffold Deliver Site-selective Dual-modality Antibody Conjugation. Chembiochem : a European journal of chemical biology (2023)
Mikesh Patel, Nafsika Forte, Charlie R Bishop, Michael J Porter, Matthew Dagwell, Kersti Karu, Vijay Chudasama, James Richard Baker
The Nitrile Bis-Thiol Bioconjugation Reaction. Journal of the American Chemical Society 146 (1) (2023)
Léa N C Rochet, Calise Bahou, Jonathan P Wojciechowski, Ilias Koutsopetras, Phyllida Britton, Richard J Spears, Ioanna A Thanasi, Baihao Shao, Lisha Zhong, Dejan-Krešimir Bučar, Abil E Aliev, Michael J Porter, Molly M Stevens, James Richard Baker, Vijay Chudasama
Use of pyridazinediones for tuneable and reversible covalent cysteine modification applied to peptides, proteins and hydrogels. Chemical science 14 (47) (2023)
Mikesh Patel, Nafsika Forte, Charlie R Bishop, Michael J Porter, Matthew Dagwell, Kersti Karu, Vijay Chudasama, James Richard Baker
The Nitrile Bis-Thiol Bioconjugation Reaction. Journal of the American Chemical Society 146 (1) (2023)
Alina Chrzastek, Ioanna A Thanasi, James A Irving, Vijay Chudasama, James Richard Baker
Dual reactivity disulfide bridging reagents; enabling new approaches to antibody fragment bioconjugation. Chemical science 13 (39) (2022)
Richard J Spears, Alina Chrzastek, Steven Y Yap, Kersti Karu, Abil E Aliev, James Richard Baker, Vijay Chudasama
Unearthing the unique stability of thiophosphonium-C-terminal cysteine adducts on peptides and proteins. Chemical communications (Cambridge, England) 58 (35) (2022)
Anders Dinesen, Alexander Winther, Archie Wall, Anders Märcher, Johan Palmfeldt, Vijay Chudasama, Jesper Wengel, Kurt Vesterager Gothelf, James Richard Baker, Kenneth A Howard
Albumin Biomolecular Drug Designs Stabilized through Improved Thiol Conjugation and a Modular Locked Nucleic Acid Functionalized Assembly. Bioconjugate chemistry 33 (2) (2022)
Roshni Malde, Michael A Parkes, Michael Staniforth, Jack M Woolley, Vasilios G Stavros, Vijay Chudasama, Helen H Fielding, James Richard Baker
Intramolecular thiomaleimide [2 + 2] photocycloadditions: stereoselective control for disulfide stapling and observation of excited state intermediates by transient absorption spectroscopy. Chemical science 13 (10) (2022)
Faiza Javaid, Camilla Pilotti, Carlotta Camilli, David Kallenberg, Calise Bahou, Jack Blackburn, James Richard Baker, John Greenwood, Stephen E Moss, Vijay Chudasama
Leucine-rich alpha-2-glycoprotein 1 (LRG1) as a novel ADC target. RSC chemical biology 2 (4) (2021)
Matthew Farleigh, Truc Thuy Pham, Zilin Yu, Jana Kim, Kavitha Sunassee, George Firth, Nafsika Forte, Vijay Chudasama, James Richard Baker, Nicholas J Long, Charlotte Rivas, Michelle T Ma
New Bifunctional Chelators Incorporating Dibromomaleimide Groups for Radiolabeling of Antibodies with Positron Emission Tomography Imaging Radioisotopes. Bioconjugate chemistry 32 (7) (2021)
Richard J Spears, Clíona McMahon, Monika Shamsabadi, Calise Bahou, Ioanna A Thanasi, Léa N C Rochet, Nafsika Forte, Fabien Thoreau, James Richard Baker, Vijay Chudasama
A novel thiol-labile cysteine protecting group for peptide synthesis based on a pyridazinedione (PD) scaffold. Chemical communications (Cambridge, England) (2021)
Calise Bahou, Peter A Szijj, Richard J Spears, Archie Wall, Faiza Javaid, Afrah Sattikar, Elizabeth A Love, James Richard Baker, Vijay Chudasama
A Plug-and-Play Platform for the Formation of Trifunctional Cysteine Bioconjugates that also Offers Control over Thiol Cleavability. Bioconjugate chemistry 32 (4) (2021)
Muhammed Haque, Nafsika Forte, James Richard Baker
Site-selective lysine conjugation methods and applications towards antibody-drug conjugates. Chemical communications (Cambridge, England) 57 (82) (2021)
Antoine Maruani, Peter A Szijj, Calise Bahou, João C F Nogueira, Stephen Caddick, James Richard Baker, Vijay Chudasama
A Plug-and-Play Approach for the De Novo Generation of Dually Functionalized Bispecifics. Bioconjugate chemistry 31 (3) (2020)
Mohammed Aljuaid, Evelina Liarou, James S Town, James Richard Baker, David M Haddleton, Paul Wilson
Synthesis and [2+2]-photodimerisation of monothiomaleimide functionalised linear and brush-like polymers. Chemical communications (Cambridge, England) 56 (66) (2020)
Marı A Maneiro, Nafsika Forte, Maria M Shchepinova, Cyrille S Kounde, Vijay Chudasama, James Richard Baker, Edward William Tate
Antibody-PROTAC Conjugates Enable HER2-Dependent Targeted Protein Degradation of BRD4. ACS chemical biology 15 (6) (2020)
Archie Wall, Karl Nicholls, Mikael B Caspersen, Stig Skrivergaard, Kenneth A Howard, Kersti Karu, Vijay Chudasama, James Richard Baker
Optimised approach to albumin-drug conjugates using monobromomaleimide-C-2 linkers. Organic & biomolecular chemistry 17 (34) (2020)
Archie Wall, Alfie G Wills, Nafsika Forte, Calise Bahou, Lisa Bonin, Karl Nicholls, Michelle T Ma, Vijay Chudasama, James Richard Baker
One-pot thiol-amine bioconjugation to maleimides: simultaneous stabilisation and dual functionalisation. Chemical science 11 (42) (2020)
Calise Bahou, Daniel A Richards, Antoine Maruani, Elizabeth A Love, Faiza Javaid, Stephen Caddick, James Richard Baker, Vijay Chudasama
Highly homogeneous antibody modification through optimisation of the synthesis and conjugation of functionalised dibromopyridazinediones. Organic & biomolecular chemistry 16 (8) (2019)
Nafsika Forte, Irene Benni, Kersti Karu, Vijay Chudasama, James Richard Baker
Cysteine-to-lysine transfer antibody fragment conjugation. Chemical science 10 (47) (2019)
Calise Bahou, Elizabeth A Love, Siobhán Leonard, Richard J Spears, Antoine Maruani, Kathryn Armour, James Richard Baker, Vijay Chudasama
Disulfide Modified IgG1: An Investigation of Biophysical Profile and Clinically Relevant Fc Interactions. Bioconjugate chemistry 30 (4) (2019)
Maurício Morais, João P M Nunes, Kersti Karu, Nafsika Forte, Irene Benni, Mark E B Smith, Stephen Caddick, Vijay Chudasama, James Richard Baker
Optimisation of the dibromomaleimide (DBM) platform for native antibody conjugation by accelerated post-conjugation hydrolysis. Organic & biomolecular chemistry 15 (14) (2018)
Nafsika Forte, Maria Livanos, Enrique Miranda, Maurício Morais, Xiaoping Yang, Vineeth S Rajkumar, Kerry Ann Chester, Vijay Chudasama, James Richard Baker
Tuning the Hydrolytic Stability of Next Generation Maleimide Cross-Linkers Enables Access to Albumin-Antibody Fragment Conjugates and tri-scFvs. Bioconjugate chemistry 29 (2) (2018)